公开(公告)号：US4306780A

公开(公告)日：1981-12-22

申请号：US57204

申请日：1979-07-13

申请人： Niro Tarumi ,  Makoto Tsuchiya ,  Shigeo Komiya ,  Eiichi Masuhara

发明人： Niro Tarumi ,  Makoto Tsuchiya ,  Shigeo Komiya ,  Eiichi Masuhara

IPC分类号： C08F20/00 ,  B29C33/00 ,  C08F20/10 ,  C08F220/30 ,  C08F251/00 ,  G02B1/04 ,  G02B5/30 ,  C08F220/20 ,  C08F228/04

CPC分类号： G02B1/041 ,  B29C33/0038 ,  C08F220/30 ,  B29L2031/7602

摘要： The present invention relates to a copolymer for high refractive lens having a refractive index equal to or higher than 1.55, obtained by copolymerization of one or more of the first monomer component having the formula (I) ##STR1## wherein R.sub.1 signifies hydrogen atom or methyl radical, R.sub.2 signifies hydrogen atom or methyl radical, and m and n signify integers 0 to 4 in total, with one or more of the radically polymerizable second monomer component, homo-polymer of which has a refractive index equal to or higher than 1.55 and, if necessary, with the radically polymerizable third monomer component, the homo-polymer of which has a refractive index lower than 1.55 and to the lens prepared from said copolymer.

摘要翻译： 本发明涉及一种折射率等于或高于1.55的高折射率透镜用共聚物，该共聚物通过一种或多种具有式（I）的第一单体组分（I）＆lt; IMAGE＆gt; R1表示氢原子或甲基，R2表示氢原子或甲基，m和n表示总共为0-4的整数，其中一个或多个可自由基聚合的第二单体组分的均聚物具有折射率相等 至1.55以上，以及如果需要，其可聚合的第三单体成分的折射率低于1.55的可自由基聚合的第三单体组分和由所述共聚物制备的透镜。

公开(公告)号：US3988274A

公开(公告)日：1976-10-26

申请号：US547543

申请日：1975-02-06

申请人： Eiichi Masuhara ,  Niro Tarumi ,  Makoto Tsuchiya

发明人： Eiichi Masuhara ,  Niro Tarumi ,  Makoto Tsuchiya

IPC分类号： G02C7/04 ,  C08F2/00 ,  C08F2/02 ,  C08F20/00 ,  C08F20/26 ,  C08F220/00 ,  C08F220/04 ,  G02B1/04 ,  C08F18/24 ,  B29D11/00 ,  C08F216/02

CPC分类号： G02B1/043

摘要： A soft contact lens having a water content of at least 45% and a tensile strength of at least 100 g/mm.sup.2 can be produced by pouring into a mold a composition consisting of 70 to 93% by weight of an alkylene glycol monoacrylate or monomethacrylate, 0.3 to 2.0% by weight of a polyfunctional monomer, 1 to 10% by weight of a monomer having at least one carboxyl group in its molecule and 5 to 20% by weight of an acrylic or methacrylic acid derivative, raising the temperature of the composition from 35.degree. C to 110.degree. C continuously to effect polymerization, processing the resulting formed product into a lens, and then swelling the lens thus obtained by hydration treatment including alkali treatment.

摘要翻译： 水分含量至少为45％，拉伸强度至少为100g / mm2的软性隐形眼镜可以通过向模具中注入由70-93％（重量）的亚烷基二醇单丙烯酸酯或单甲基丙烯酸酯组成的组合物， 0.3〜2.0重量％的多官能单体，1〜10重量％的分子中具有至少一个羧基的单体和5〜20重量％的丙烯酸或甲基丙烯酸衍生物，提高组合物的温度 从35℃至110℃持续进行聚合，将所得成形体加工成透镜，然后通过包括碱处理的水合处理使由此获得的透镜膨胀。

公开(公告)号：US4650843A

公开(公告)日：1987-03-17

申请号：US687501

申请日：1985-01-02

申请人： Yuuichi Yokoyama ,  Eiichi Masuhara ,  Yoshinori Kadoma ,  Niro Tarumi ,  Makoto Tsuchiya

发明人： Yuuichi Yokoyama ,  Eiichi Masuhara ,  Yoshinori Kadoma ,  Niro Tarumi ,  Makoto Tsuchiya

IPC分类号： C08F220/28 ,  G02B1/04 ,  C08F214/18 ,  G02C7/04

CPC分类号： C08F220/28 ,  G02B1/043

摘要： When trifluoroethyl methacrylate, hexafluoroisopropyl methacrylate, pentafluoro-n-propyl methacrylate and/or pentafluoro-n-butyl methacrylate which are fluorine-containing monomers, are added to a conventional monomer mixture for producing a soft contact lens, the resulting soft contact lens has the same optical properties and elasticity as conventional soft contact lenses have, and is very superior to the conventional ones in resistance to deposit and in shape stability.

摘要翻译： 当将甲基丙烯酸六氟异丙酯，甲基丙烯酸六氟异丙酯，甲基丙烯酸五氟正丙酯和/或甲基丙烯酸五氟正丁酯作为含氟单体添加到用于制备软性隐形眼镜的常规单体混合物中时，所得软性隐形眼镜具有 与传统的软性隐形眼镜相同的光学性质和弹性具有并且非常优于传统的柔性隐形眼镜在抵抗沉积和形状稳定性方面。

公开(公告)号：US4373076A

公开(公告)日：1983-02-08

申请号：US315127

申请日：1981-10-26

申请人： Niro Tarumi ,  Mitsuo Sugimura ,  Shigeo Komiya ,  Makoto Tsuchiya

发明人： Niro Tarumi ,  Mitsuo Sugimura ,  Shigeo Komiya ,  Makoto Tsuchiya

IPC分类号： C08F218/00 ,  G02B1/04 ,  C08F26/06

CPC分类号： C08F218/00 ,  G02B1/04 ,  Y10T428/31649

摘要： A high refractive lens of a terpolymer produced by the polymerization of ternary monomers comprising diethylene glycol bisallyl carbonate, triallylisocyanurate, and benzyl methacrylate. This lens is considerably improved in its physical properties necessary for lens such as superficial hardness, transmittance, and adhesion strength of glass film coated on the surface, as well as having a high refractive index.

摘要翻译： 通过聚合包含二甘醇双烯丙基碳酸酯，三烯丙基异氰脲酸酯和甲基丙烯酸苄酯的三元单体的聚合产生的三元共聚物的高折射透镜。 这种透镜在透镜所需的物理性能方面有显着改善，例如表面硬度，透光率和涂覆在表面上的玻璃膜的粘附强度以及具有高折射率。

公开(公告)号：US4329378A

公开(公告)日：1982-05-11

申请号：US102348

申请日：1979-12-11

申请人： Niro Tarumi ,  Makoto Tsuchiya ,  Kunio Sasaki

发明人： Niro Tarumi ,  Makoto Tsuchiya ,  Kunio Sasaki

IPC分类号： B29D11/00 ,  B41M1/30 ,  B41M3/06 ,  G02B1/04 ,  G02C7/02 ,  B05D5/06

CPC分类号： G02C7/021 ,  B29D11/00 ,  B41M1/30 ,  B41M3/06 ,  G02B1/041 ,  B29K2995/0018

摘要： Plastic eyeglass lenses and the like are marked with an identifying character or symbol by applying to the surface thereof or dissolving or comelting therein a flourescent dyestuff according to the disclosed method. When the proper amount of flourescent dyestuff is included the lens appears normal in sunlight but is characteristically marked in whole or in part under ultraviolet light depending on the area treated.

摘要翻译： 根据所公开的方法，塑料眼镜镜片等通过施加到其表面或溶解或熔化荧光染料来标记识别字符或符号。 当包含适量的荧光染料时，透镜在阳光下看起来正常，但是根据所处理的区域，全部或部分地在紫外光下标记。

公开(公告)号：US5426050A

公开(公告)日：1995-06-20

申请号：US167112

申请日：1993-12-16

申请人： Yasushi Morinaga ,  Makoto Tsuchiya

发明人： Yasushi Morinaga ,  Makoto Tsuchiya

IPC分类号： C12N15/09 ,  C12N1/21 ,  C12N15/00 ,  C12N15/70 ,  C12N15/77 ,  C12R1/13 ,  C12R1/15

CPC分类号： C12N15/77 ,  C12N15/70

摘要： A recombinant plasmid vector is provided which is capable of replicating and expressing in a Coryneform bacterial cell, which plasmid vector is pEC 701, pEC 702, pEC 801, pEC 830 or pEC 901.

摘要翻译： 提供了能够在棒状细菌细胞中复制和表达的重组质粒载体，该质粒载体是pEC 701，pEC 702，pEC 801，pEC 830或pEC 901。

公开(公告)号：US06211965B1

公开(公告)日：2001-04-03

申请号：US09377181

申请日：1999-08-19

申请人： Makoto Tsuchiya ,  Junji Hazama

发明人： Makoto Tsuchiya ,  Junji Hazama

IPC分类号： G01B902

CPC分类号： G03F7/70775

摘要： A laser interferometer for detecting the position of a moving object in a Y-direction when the object moves in an X-direction has a separating optical system that moves in the X-direction at a speed different from that of the moving object. A laser beam is separated by the separating optical system into a reference beam and a measurement beam, which are individually directed toward a reference mirror and a moving mirror on the moving object. The light of the measurement beam reflected from the moving mirror, and the light of the reference beam reflected from the reference mirror are received by a photodetector via the separating optical system, and the photoelectric conversion signal of the interference light is output as information concerning the position of the moving object in the Y-direction. A fixed mirror that is shorter than the moving object can be used because the separating optical system also moves in the X-direction.

摘要翻译： 当物体沿X方向移动时，用于检测运动物体在Y方向上的位置的激光干涉仪具有以与运动物体不同的速度在X方向上移动的分离光学系统。 激光束被分离光学系统分离成参考光束和测量光束，它们分别指向移动物体上的参考反射镜和移动反射镜。 从移动镜反射的测量光的光和从参考反射镜反射的参考光的光经由分离光学系统被光电检测器接收，并且干涉光的光电转换信号作为关于 移动物体在Y方向上的位置。 由于分离光学系统也沿X方向移动，所以可以使用比移动物体短的固定镜。

公开(公告)号：US06178667B2

公开(公告)日：2001-01-30

申请号：US09296543

申请日：1999-04-22

申请人： Yasunori Kaneko ,  Makoto Tsuchiya

发明人： Yasunori Kaneko ,  Makoto Tsuchiya

IPC分类号： A43B500

CPC分类号： A43B7/1425 ,  A43B7/1435 ,  A43B7/144 ,  A43B7/145 ,  A43C15/16

摘要： A sole of a baseball spiked shoe has a toe portion projection, a first metatarsal head projection, a stepping portion projection, and a fifth metatarsal head projection provided at a fore foot portion at the bottom plane of the shoe sole, and a heel medial projection, a heel anterior projection, a heel posterior projection, and a heel lateral projection provided at the heel portion. Each projection is provided at an appropriate angle with respect to the longitudinal line of the foot.

摘要翻译： 棒球加注鞋的鞋底具有脚趾部分突出部，第一跖骨头部突出部，步进部分突出部和设置在鞋底底面的前脚部处的第五跖骨头突起，以及脚跟内侧突起 ，跟部前突起，后跟后突出部和设置在脚跟部分处的跟部侧向突出部。 每个突起相对于脚的纵向线以适当的角度设置。

公开(公告)号：US5547864A

公开(公告)日：1996-08-20

申请号：US295670

申请日：1994-09-08

申请人： Hisashi Kawasaki ,  Makoto Tsuchiya ,  Kiyoshi Miwa ,  Yoshio Kawahara

发明人： Hisashi Kawasaki ,  Makoto Tsuchiya ,  Kiyoshi Miwa ,  Yoshio Kawahara

IPC分类号： C07K14/345 ,  C12N15/31 ,  C12N15/77 ,  C12P13/04 ,  C12P1/04 ,  C07K14/34 ,  C12N1/20

CPC分类号： C12P13/04 ,  C07K14/345 ,  C12N15/77

摘要： A DNA fragment containing a gene coding for a novel cell surface layer protein derived from Brevibacterium lactofermentum and having two sequences of:(1)Thr-Leu-Arg-Gln-His-Tyr-Ser-Ser-Leu-Ile-Pro-Asn-Leu-Phe-Ile-Ala-Ala-Val-Gly-Asn-Ile-Asn-Glu-Leu-Asn-Asn-Ala-Asp-Gln-Ala-Ala-Arg-Glu-Leu-Phe-Leu-Asp-Trp-Asp-Thr (SEQ ID NO: 1) and:(2)Asn-Lys-Thr-Asp-Phe-Ala-Glu-Ile-Glu-Leu-Tyr-Asp-Val-Leu-Tyr-Thr-Asp-Ala-Asp-Ile-Ser-Gly-Asp-Ala-Pro-Leu-Leu-Ala-Pro-Ala-Tyr-Lys (SEQ ID NO: 2)in the molecule, and having a molecular weight of about 63,000 dalton is introduced into Coryneform bacteria to obtain a transformant, or originate a mutant strain being sufficient in the novel cell surface layer protein, which is used for producing a useful substance such as an L-amino acid by an L-amino acid fermentation method.

摘要翻译： PCT No.PCT / JP94 / 00039 Sec。 371日期1994年9月8日 102（e）1994年9月8日PCT PCT 1994年1月13日PCT公布。 公开号WO94 / 15963 日期1994年7月21日包含编码来自乳发酵短杆菌的新型细胞表面蛋白质的基因的DNA片段，具有以下两个序列：（1）Thr-Leu-Arg-Gln-His-Tyr-Ser-Ser-Leu- Ile-Pro-Asn-Leu-Phe-Ile-Ala-Ala-Val-Gly-Asn-Ile-Asn-Glu-Leu-Asn-Asn-Ala-Asp-Gln-Ala-Ala-Arg-Glu-Leu- Phe-Leu-Asp-Trp-Asp-Thr（SEQ ID NO：1）和（2）Asn-Lys-Thr-Asp-Phe-Ala-Glu-Ile-Glu-Leu-Tyr-Asp-Val-Leu -Tyr-Thr-Asp-Ala-Asp-Ala-Ser-Gly-Asp-Ala-Pro-Leu-Leu-Ala-Pro-Ala-Tyr-Lys（SEQ ID NO：2） 将约63,000道尔顿的分子量引入棒状细菌以获得转化体，或产生在新型细胞表面层蛋白中足够的突变菌株，其用于通过L-乳酸生产有用物质如L-氨基酸， 氨基酸发酵法。

公开(公告)号：US5374663A

公开(公告)日：1994-12-20

申请号：US7027

申请日：1993-01-21

申请人： Masanori Daicho ,  Yuuichi Yokoyama ,  Makoto Tsuchiya

发明人： Masanori Daicho ,  Yuuichi Yokoyama ,  Makoto Tsuchiya

IPC分类号： A61F2/16 ,  A61L27/50 ,  A61L27/00

CPC分类号： A61L27/50 ,  A61F2/1613 ,  A61L2430/16 ,  Y10S514/912 ,  Y10S514/972

摘要： The present invention relates to a process for producing a cyanopsia-correctable intraocular lens, which process is characterized by, in polymerizing a monomer capable of forming a transparent lens material upon polymerization to obtain an intraocular lens, adding, as an essential component, at least one member of yellow, yellowish brown and orange colorants and, as an optional components, an U.V. absorber and a crosslinking monomer. The intraocular lens obtained by the present invention has a light absorption characteristic close to that of human crystalline lens and is effective for correction of cyanopsia.

摘要翻译： 本发明涉及一种可产生蓝斑修正眼内透镜的方法，该方法的特征在于在聚合时聚合能够形成透明晶状体材料的单体以获得眼内透镜，至少添加作为必需组分的 黄色，黄棕色和橙色着色剂的一个成员，以及作为任选组分的UV 吸收剂和交联单体。 通过本发明获得的眼内透镜具有接近于人晶状体的光吸收特性，对于修正蓝斑有效。