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公开(公告)号：US08716204B2
公开(公告)日：2014-05-06
申请号：US13191193
申请日：2011-07-26
IPC分类号： C10M169/06 , G01N3/56
CPC分类号： A61K35/16 , A61K31/685 , A61K31/728 , A61K38/1722 , A61K38/38 , A61K45/06 , A61K2300/00
摘要： Artificial or synthetic synovial fluids and methods for making such fluids are disclosed. The fluid includes selected proteins, phospholipids and hyaluronic acid and mimics the properties of human synovial fluid.
摘要翻译： 公开了人造或合成滑液和制造这种流体的方法。 流体包括选定的蛋白质，磷脂和透明质酸，并且模拟人滑液的性质。
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公开(公告)号：US20120186356A1
公开(公告)日：2012-07-26
申请号：US13191193
申请日：2011-07-26
IPC分类号： G01B5/30 , C10M113/00
CPC分类号： A61K35/16 , A61K31/685 , A61K31/728 , A61K38/1722 , A61K38/38 , A61K45/06 , A61K2300/00
摘要： Artificial or synthetic synovial fluids and methods for making such fluids are disclosed. The fluid includes selected proteins, phospholipids and hyaluronic acid and mimics the properties of human synovial fluid.
摘要翻译： 公开了人造或合成滑液和制造这种流体的方法。 流体包括选定的蛋白质，磷脂和透明质酸，并且模拟人滑液的性质。
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公开(公告)号：US08467648B2
公开(公告)日：2013-06-18
申请号：US13448003
申请日：2012-04-16
申请人： Liang Dong , Brian Thomas , Libin Fu
发明人： Liang Dong , Brian Thomas , Libin Fu
CPC分类号： G02F1/365 , C03B37/0122 , C03B2201/82 , C03B2201/86 , C03B2203/10 , C03B2203/14 , C03B2203/42 , C03B2205/08 , C03B2205/10 , G02B6/02214 , G02B6/02333 , G02B6/02357 , G02F1/395 , H01S3/0057 , H01S3/06729 , H01S3/06754
摘要： Various embodiments of optical fiber designs and fabrication processes for ultra small core fibers (USCF) are disclosed. In some embodiments, the USCF includes a core that is at least partially surrounded by a region comprising first features. The USCF further includes a second region at least partially surrounding the first region. The second region includes second features. In an embodiment, the first features are smaller than the second features, and the second features have a filling fraction greater than about 90 percent. The first features and/or the second features may include air holes. Embodiments of the USCF may provide dispersion tailoring. Embodiments of the USCF may be used with nonlinear optical devices configured to provide, for example, a frequency comb or a supercontinuum.
摘要翻译： 公开了用于超小芯纤维（USCF）的光纤设计和制造工艺的各种实施例。 在一些实施例中，USCF包括至少部分地被包括第一特征的区域包围的芯。 USCF还包括至少部分围绕第一区域的第二区域。 第二个区域包括第二个特征。 在一个实施例中，第一特征小于第二特征，并且第二特征具有大于约90％的填充分数。 第一特征和/或第二特征可以包括气孔。 USCF的实施例可以提供色散调整。 USCF的实施例可以与被配置为提供例如频率梳或超连续谱的非线性光学装置一起使用。
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公开(公告)号：US08262730B2
公开(公告)日：2012-09-11
申请号：US11608128
申请日：2006-12-07
申请人： Brian Thomas , Kai Zhang , Garryl Hudgins , Robert Hodorek
发明人： Brian Thomas , Kai Zhang , Garryl Hudgins , Robert Hodorek
CPC分类号： A61L24/06 , A61L24/0031 , A61L27/16 , A61L27/52 , C08L29/04
摘要： This invention provides methods and processes to attach or bond hydrogels to suitable surfaces using irradiation techniques and also provides methods and processes to create crosslinked regions in hydrogel articles using these irradiation techniques. Specifically, lasers at wavelengths tuned to the irradiation absorption bands of hydroxyl groups, carboxylic acid groups or water may be used to attach or bond hydrogels to surfaces such as soft tissue and hydrogel surfaces or to crosslink regions in hydrogel articles.
摘要翻译： 本发明提供了使用照射技术将水凝胶附着或粘合到合适表面上的方法和方法，并且还提供使用这些照射技术在水凝胶制品中产生交联区域的方法和方法。 具体地，可以使用调谐到羟基，羧酸基团或水的照射吸收带的波长的激光器将水凝胶附着或粘合到表面，例如软组织和水凝胶表面，或者在水凝胶制品中交联区域。
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公开(公告)号：US08062739B2
公开(公告)日：2011-11-22
申请号：US11848698
申请日：2007-08-31
申请人： Kaifeng Liu , Brian Thomas , Steven Charlebois
发明人： Kaifeng Liu , Brian Thomas , Steven Charlebois
摘要： The present invention provides a hydrogel article having a multi-layered structure and exhibiting a gradient in polymer molecular weight. The invention also provides a method of forming a hydrogel article having a multi-layered structure and exhibiting a gradient in polymer molecular weight.
摘要翻译： 本发明提供具有多层结构且呈现聚合物分子量梯度的水凝胶制品。 本发明还提供了形成具有多层结构且呈现聚合物分子量梯度的水凝胶制品的方法。
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6.发明申请Synthetic Polymer Adhesives And Methods For Making, Using And Delivering The Same 有权合成聚合物粘合剂及其制备，使用和提供方法公开(公告)号：US20110276088A1
公开(公告)日：2011-11-10
申请号：US13099549
申请日：2011-05-03
申请人： Brian Thomas , Donald Yakimicki
发明人： Brian Thomas , Donald Yakimicki
CPC分类号： A61B17/00491 , A61B2017/00495 , A61B2017/00707 , A61L24/043 , C08K3/22 , C08K3/38 , C09J129/04 , G09B23/285
摘要： A synthetic polymer based adhesive formulation that has properties substantially simulating selected properties of fibrin glue, and methods of making and using the same. The adhesive formulation includes a discrete acid solution and discrete base solution that when combined form a synthetic polymer based adhesive that substantially simulates selected properties of fibrin glue. The discrete acid solution includes a polymer and a cross-linking agent precursor. The discrete base solution includes a polymer and a base.
摘要翻译： 具有基本上模拟纤维蛋白胶的选择性质的性质的合成聚合物基粘合剂制剂及其制备和使用方法。 粘合剂制剂包括离散的酸溶液和离散的碱性溶液，当组合形成基本上模拟纤维蛋白胶的选定性质的基于合成聚合物的粘合剂时。 离散酸溶液包括聚合物和交联剂前体。 离散碱溶液包括聚合物和碱。
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公开(公告)号：US20110047170A1
公开(公告)日：2011-02-24
申请号：US12916410
申请日：2010-10-29
申请人： Shawn Thomas , Gregory Gray , Michael Woodfin , Warner Mizell , Brian Thomas
发明人： Shawn Thomas , Gregory Gray , Michael Woodfin , Warner Mizell , Brian Thomas
CPC分类号： G06F17/30864 , G06F9/4451 , G06F17/211 , G06F17/24 , G06F17/30 , G06Q10/06 , G06Q30/02 , G06Q40/02 , G06Q99/00 , Y10S707/99948
摘要： The method and system of the present invention provides an improved technique for replacing, implementing and managing computer-related assets. A technician accesses the World Wide Web through a user's computer. The information resident on the computer, including information regarding the computer and the user's preferences, are downloaded to a remote storage medium through the World Wide Web. Once downloaded, all information may be removed from the user's computer. Subsequently, the technician accesses another computer such as, for example, a new computer that has been assigned to the same user. The technician accesses the World Wide Web through the new computer and downloads the information previously stored on the remote storage medium. This information can then be used to install the user's prior applications, settings and preferences on the new computer.
摘要翻译： 本发明的方法和系统提供了一种用于替换，实施和管理计算机相关资产的改进技术。 技术人员通过用户的计算机访问万维网。 计算机上驻留的信息（包括有关计算机的信息和用户的偏好）通过万维网下载到远程存储介质。 一旦下载，所有信息可能会从用户的计算机中删除。 随后，技术人员访问另一台计算机，例如已分配给同一用户的新计算机。 技术人员通过新计算机访问万维网，并下载先前存储在远程存储介质上的信息。 然后，可以将此信息用于在新计算机上安装用户的先前应用程序，设置和首选项。
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公开(公告)号：US20100330306A1
公开(公告)日：2010-12-30
申请号：US12490464
申请日：2009-06-24
CPC分类号： B41M5/44 , B41M2205/02 , B41M2205/06 , B41M2205/32 , B41M2205/36 , B41M2205/38 , G03G7/0026 , G03G7/004 , G03G7/0046 , G03G7/0053 , Y10T428/24975 , Y10T428/31725 , Y10T428/31786 , Y10T428/31902 , Y10T428/31938
摘要： An image receiving element is a composite of two or more extruded layers on a support including, in order, an extruded compliant layer, an extruded antistatic tie layer, and an image receiving layer that may also be extruded. The extruded compliant layer is non-voided and comprises from about 10 to about 40 weight % of at least one elastomeric polymer. This image receiving element can be disposed on a support to form a thermal dye transfer receiver element, an electrophotographic image receiver element, or a thermal wax receiver element. Two or more extruded layers can be co-extruded.
摘要翻译： 图像接收元件是在支撑体上的两个或更多个挤出层的复合物，其依次包括挤出的柔顺层，挤出的抗静电粘结层和也可以挤出的图像接收层。 挤出的柔顺层是无孔的并且包含约10至约40重量％的至少一种弹性体聚合物。 该图像接收元件可以设置在支撑件上以形成热染料转移接受元件，电子照相图像接收元件或热蜡接收元件。 可以共挤出两个或多个挤出层。
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公开(公告)号：US20090035344A1
公开(公告)日：2009-02-05
申请号：US11833549
申请日：2007-08-03
申请人： Brian Thomas , Kai Zhang
发明人： Brian Thomas , Kai Zhang
CPC分类号： A61L27/52 , C08J3/075 , C08J2300/00 , C08J2329/04
摘要： The invention provides a multi-polymer hydrogel article having a first polymeric, water-swellable material and a second polymeric material, organized such that a first region substantially comprises the first polymeric, water-swellable material, a second region adjacent the first region comprises a mixture of the first polymeric, water-swellable material and the second polymeric material, and a third region adjacent the second region substantially comprises the second polymeric material. The article exhibits an increasing concentration gradient of the second polymeric material moving from the first region, through the second region, to the third region. The invention also provides methods for forming a multi-polymer hydrogel article by (a) forming a hydrogel structure using a first polymeric, water-swellable material, (b) creating an aerogel structure having a plurality of open pores by dehydrating the hydrogel structure, (c) contacting the aerogel structure with a second polymeric material to incorporate the second polymeric material into at least a portion of the plurality of open pores to form the multi-polymer hydrogel article, and (d) rehydrating the multi-polymer hydrogel article.
摘要翻译： 本发明提供了具有第一聚合物，水可溶胀材料和第二聚合物材料的多聚物水凝胶制品，其被组织成使得第一区域基本上包含第一聚合物，水可溶胀材料，与第一区域相邻的第二区域包括 第一聚合物，水可溶胀材料和第二聚合物材料的混合物以及与第二区域相邻的第三区域基本上包括第二聚合物材料。 该制品表现出第二聚合物材料从第一区域通过第二区域移动到第三区域的浓度梯度增加。 本发明还提供了通过（a）使用第一聚合物，水可溶胀材料形成水凝胶结构来形成多聚物水凝胶制品的方法，（b）通过使水凝胶结构脱水来产生具有多个开孔的气凝胶结构， （c）使所述气凝胶结构与第二聚合物材料接触，以将所述第二聚合物材料结合到所述多个开孔中的至少一部分中以形成所述多聚物水凝胶制品，和（d）使所述多聚物水凝胶制品再水化。
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10.发明申请公开(公告)号：US20060178707A1
公开(公告)日：2006-08-10
申请号：US11055731
申请日：2005-02-10
申请人： Brian Thomas , Jay Millerhagen , Michael Gebauer
发明人： Brian Thomas , Jay Millerhagen , Michael Gebauer
IPC分类号： A61N1/362
CPC分类号： A61B5/0472 , A61N1/37247 , A61N1/37258 , G06F19/00 , G16H40/63
摘要： A medical device programmer or other external system capable of programming an implantable CRM device includes a wide-QRS detection and alerting system. Upon detection of a wide QRS complex, a wide-QRS indicator produces a visual indication of the detection using one or more presentation devices such as a display screen and a printer to alert a physician or other caregiver.
摘要翻译： 能够编程可植入CRM设备的医疗设备编程器或其它外部系统包括宽QRS检测和警报系统。 在检测到宽QRS波段时，宽QRS指示器使用一个或多个呈现装置（诸如显示屏和打印机）产生检测的视觉指示，以警告医生或其他看护者。
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