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    Medicament Preparation Devices, Methods, and Systems
    2.
    发明申请
    Medicament Preparation Devices, Methods, and Systems 有权

    公开(公告)号：US20220313884A1

    公开(公告)日：2022-10-06

    申请号：US17708923

    申请日：2022-03-30

    申请人： NxStage Medical, Inc.

    发明人： Goetz FRIEDERICHS ,  Gregory YANTZ

    IPC分类号： A61M1/28 ,  A61M39/28

    摘要： A system for preparing a medicament for use by a medicament user includes a proportioning machine with a controller and pumping and clamping actuators to engage a fluid circuit having pumping and clamping portions that engage with respective actuators of the proportioning machine. The fluid circuit includes a mixing container that is initially empty and later filled with two different concentrated medicaments from different concentrate containers and with purified water. The proportioning machine is configured to receive purified water and to mix it with the concentrated medicaments to produce a medicament and to output the medicament to a medicament consumer in such a way that to the medicament consumer the medicament appears to be provided from a bag of medicament. Custom mini batches of medicament may be produced by varying the amount of the concentrates and water.

    Medicament Preparation Devices, Methods, and Systems
    5.
    发明申请
    Medicament Preparation Devices, Methods, and Systems 有权

    公开(公告)号：US20220305180A1

    公开(公告)日：2022-09-29

    申请号：US17702206

    申请日：2022-03-23

    申请人： NxStage Medical, Inc.

    发明人： Goetz FRIEDERICHS ,  Gregory YANTZ

    IPC分类号： A61M1/16 ,  A61M1/28 ,  B01F35/71 ,  B01F25/60

    摘要： A system for preparing a medicament for use by a medicament user includes a proportioning machine with a controller and pumping and clamping actuators to engage a fluid circuit having pumping and clamping portions that engage with respective actuators of the proportioning machine. The fluid circuit includes a mixing container that is initially empty and later filled with two different concentrated medicaments from different concentrate containers and with purified water. The circuit may include one or more pre-connected fluid quality sensors, such as conductivity sensors, in fluid communication with the mixing container. The proportioning machine is configured to receive purified water and to mix it with the concentrated medicaments to produce a medicament and to output the medicament to a medicament consumer. Little or no mixed fluid is lost during conductivity testing and custom mini batches of medicament may be produced by varying the amount of the concentrates and water.

    Water Treatment Systems, Devices, and Methods for Fluid Preparation
    7.
    发明申请
    Water Treatment Systems, Devices, and Methods for Fluid Preparation 有权

    公开(公告)号：US20210178041A1

    公开(公告)日：2021-06-17

    申请号：US17189879

    申请日：2021-03-02

    申请人： NxStage Medical, Inc.

    发明人： Goetz FRIEDERICHS ,  Dennis M. TREU ,  Jeffrey H. BURBANK ,  Yuriy N. TATASHIN

    IPC分类号： A61M1/16 ,  C02F1/28 ,  C02F1/42

    摘要： A method of automatically ensuring against chloramine contamination in purified product water includes supplying input water to the system and purifying the water to generate the purified product water. The purifying includes removing chlorine and chloramine contamination from the water using a carbon filter and supplying chlorine-depleted water to a deionization filter, and deionizing the chlorine-depleted water using said deionization filter. The product water is supplied to a sensor for continuous monitoring of the resistivity of the purified product water by the first sensor, and an alarm is generated indicating possible chloramine breakthrough when the resistivity of the product water falls below a predetermined resistivity level, which is selected to provide a reserve filter capacity before breakthrough would occur. The carbon filter is replaced at least responsively to the alarm to ensure excess capacity of said carbon filter sufficient to prevent chloramine breakthrough in said product water.

    Medicament Preparation Devices, Methods, and Systems
    9.
    发明申请
    Medicament Preparation Devices, Methods, and Systems 有权

    公开(公告)号：US20220305182A1

    公开(公告)日：2022-09-29

    申请号：US17704710

    申请日：2022-03-25

    申请人： NxStage Medical, Inc.

    发明人： Goetz FRIEDERICHS ,  Gregory YANTZ

    IPC分类号： A61M1/28 ,  A61M1/16 ,  A61M39/28

    摘要： A system for preparing a medicament for use by a medicament user includes a proportioning machine with a controller and pumping and clamping actuators to engage a fluid circuit having pumping and clamping portions that engage with respective actuators of the proportioning machine. The fluid circuit includes a mixing container that is initially empty and later filled with two different concentrated medicaments from different concentrate containers and with purified water. The circuit may include one or more pre-connected fluid quality sensors, such as conductivity sensors, in fluid communication with the mixing container. A single sterilizing filter is fluidly connected to two different medicament concentrates and the concentrates pass through the sterilizing filter. The sterilizing filter is tested to ensure its integrity. Little or no mixed fluid is lost during conductivity testing and custom mini batches of medicament may be produced by varying the amount of the concentrates and water.

    Medicament Preparation Devices, Methods, and Systems
    10.
    发明申请
    Medicament Preparation Devices, Methods, and Systems 有权

    公开(公告)号：US20220296795A1

    公开(公告)日：2022-09-22

    申请号：US17695176

    申请日：2022-03-15

    申请人： NxStage Medical, Inc.

    发明人： Goetz FRIEDERICHS ,  Gregory YANTZ

    IPC分类号： A61M1/28 ,  A61M39/28 ,  A61M39/24 ,  A61M1/16

    摘要： A system for preparing a medicament for use by a medicament user includes a proportioning machine with a controller and pumping and clamping actuators to engage a fluid circuit having pumping and clamping portions that engage with respective actuators of the proportioning machine. The fluid circuit includes a mixing container that is prefilled with concentrated medicament. The proportioning machine is configured to receive purified water and to mix it with the concentrated medicament to produce a medicament and to output the medicament to a medicament consumer in such a way that to the medicament consumer the medicament appears to be provided from a bag of medicament.