公开(公告)号：US06124242A

公开(公告)日：2000-09-26

申请号：US336731

申请日：1999-06-21

申请人： Oliver Wagner ,  Franz Rohl ,  Klaus Grossmann ,  Ralf-Michael Schmidt ,  Uwe Sonnewald ,  Mohammad Hajirezaei

发明人： Oliver Wagner ,  Franz Rohl ,  Klaus Grossmann ,  Ralf-Michael Schmidt ,  Uwe Sonnewald ,  Mohammad Hajirezaei

IPC分类号： A01N43/78 ,  C07D277/82

CPC分类号： C07D277/82 ,  A01N43/78

摘要： There are described ferredoxin:NADP reductase inhibitors, an assay system for the search for such inhibitors, and their use as herbicides.

摘要翻译： 描述了铁氧还蛋白：NADP还原酶抑制剂，用于寻找这些抑制剂的测定系统及其作为除草剂的用途。

公开(公告)号：US20070113300A1

公开(公告)日：2007-05-17

申请号：US10581293

申请日：2004-11-30

申请人： Thomas Ehrhardt ,  Andreas Reindl ,  Annette Freund ,  Ralf-Michael Schmidt ,  Uwe Sonnewald ,  Marc Nigel ,  Wolfgang Lein ,  Frederik Bornke ,  Kirsten Deist

发明人： Thomas Ehrhardt ,  Andreas Reindl ,  Annette Freund ,  Ralf-Michael Schmidt ,  Uwe Sonnewald ,  Marc Nigel ,  Wolfgang Lein ,  Frederik Bornke ,  Kirsten Deist

IPC分类号： A01H1/00 ,  C12Q1/37 ,  C12P21/06 ,  A01N25/00 ,  C12N9/48 ,  C12N5/04 ,  C12N15/82 ,  C07H21/04

CPC分类号： C12N9/14 ,  C12N15/8261 ,  C12Q1/37 ,  G01N33/56961 ,  G01N33/573 ,  Y02A40/146

摘要： The present invention relates to Clp-protease, which, when absent, brings about reduced growth and chlorotic leaves as target for herbicides. For this purpose, novel nucleic acid sequences encompassing SEQ ID NO:3, SEQ ID NO:11 and SEQ ID NO: 17 and functional equivalents of SEQ ID NO:3, SEQ ID NO:11 and SEQ ID NO: 17 are provided. Moreover, the present invention relates to the use of Clp-protease in a method for identifying compounds with herbicidal or growth-regulatory activity, and to the use of the compounds identified by this method as herbicides or growth regulators.

摘要翻译： 本发明涉及Clp-蛋白酶，当不存在时，会产生减少的生长和褪绿叶作为除草剂的靶标。 为此，提供包含SEQ ID NO：3，SEQ ID NO：11和SEQ ID NO：17的新型核酸序列和SEQ ID NO：3，SEQ ID NO：11和SEQ ID NO：17的功能等同物。 此外，本发明涉及Clp-蛋白酶在鉴定具有除草或生长调节活性的化合物的方法中的用途，以及通过该方法鉴定的化合物作为除草剂或生长调节剂的用途。

公开(公告)号：US06610840B2

公开(公告)日：2003-08-26

申请号：US09799895

申请日：2001-03-07

申请人： Uwe Sonnewald ,  Marcus Ebneth ,  Ralf-Michael Schmidt

发明人： Uwe Sonnewald ,  Marcus Ebneth ,  Ralf-Michael Schmidt

IPC分类号： C12N1529

CPC分类号： C12N15/8225 ,  C12N15/8222 ,  C12N15/8234

摘要： The present invention relates to a method of isolating a promoter, which causes, in plants, permanent Mesophyll-specific expression of an operably linked encoding nucleotide sequence, for example a sequence which imparts resistance or an increase in the photosynthetic performance.

摘要翻译： 本发明涉及一种分离启动子的方法，其在植物中引起可操作地连接的编码核苷酸序列的永久性叶肉特异性表达，例如赋予抗性或增加光合性能的序列。

公开(公告)号：US20070042451A1

公开(公告)日：2007-02-22

申请号：US10578637

申请日：2004-10-27

申请人： Thomas Ehrhardt ,  Andreas Reindl ,  Annette Freund ,  Ralf-Michael Schmidt ,  Uwe Sonnewald ,  Marc Nigel ,  Wolfgang Lein ,  Frederik Bornke ,  Kirsten Deist

发明人： Thomas Ehrhardt ,  Andreas Reindl ,  Annette Freund ,  Ralf-Michael Schmidt ,  Uwe Sonnewald ,  Marc Nigel ,  Wolfgang Lein ,  Frederik Bornke ,  Kirsten Deist

IPC分类号： C12Q1/48 ,  A01N63/00

CPC分类号： C12N15/8274 ,  C12N9/00

摘要： The invention relates to the use of glycine decarboxylase complex, which is used as a target for herbicides in the absence of growth retardations and chlorotic leaves. Novel nucleic acid sequences comprising SEQ ID NO:1 and functional equivalents of SEQ ID NO:1 are thus disclosed. The invention also relates to the use of glycine decarboxylase complex and the functional equivalents thereof in a method for identifying compounds having a herbicidal or growth-regulatory effect, in addition to the use of said compounds identified via said method as herbicides or growth regulators.

摘要翻译： 本发明涉及甘氨酸脱羧酶复合物的使用，其在不存在生长迟缓和褪绿叶的情况下用作除草剂的靶标。 因此，公开了包含SEQ ID NO：1和SEQ ID NO：1的功能等同物的新型核酸序列。 本发明还涉及除用于通过所述方法鉴定的所述化合物作为除草剂或生长调节剂之外，甘氨酸脱羧酶复合物及其功能等同物用于鉴定具有除草或生长调节作用的化合物的方法中。

公开(公告)号：US20070003934A1

公开(公告)日：2007-01-04

申请号：US10581223

申请日：2004-11-30

申请人： Thomas Ehrhardt ,  Andreas Reindl ,  Annette Freund ,  Ralf-Michael Schmidt ,  Uwe Sonnewald ,  Marc Nigel ,  Wolfgang Lein ,  Frederik Bornke

发明人： Thomas Ehrhardt ,  Andreas Reindl ,  Annette Freund ,  Ralf-Michael Schmidt ,  Uwe Sonnewald ,  Marc Nigel ,  Wolfgang Lein ,  Frederik Bornke

IPC分类号： C12Q1/68 ,  C12Q1/48 ,  C12P19/34 ,  A01N25/00

CPC分类号： A01N61/00 ,  C12N9/1007 ,  C12N15/8274 ,  G01N2333/91011 ,  G01N2500/00

摘要： The present invention relates to the use of 2-methyl-6-solanylbenzoquinone methyltransferase which, when absent, brings about retarded growth and chlorotic leaves, as target for herbicides. In this context, there are provided novel nucleic acid sequences comprising SEQ ID NO:5 and SEQ ID NO:7 and corresponding functional equivalents. Moreover, the present invention relates to the use of 2-methyl-6-solanylbenzoquinone methyltransferase and its functional equivalents in a method for identifying herbicidal or growth-regulatory compounds, and to the use of the compounds identifed via the method as herbicides or growth regulators.

摘要翻译： 本发明涉及2-甲基-6-苯甲酰基苯并醌甲基转移酶的用途，当不存在时，会导致延迟生长和褪绿叶作为除草剂的靶标。 在本文中，提供了包含SEQ ID NO：5和SEQ ID NO：7的新型核酸序列和相应的功能等同物。 此外，本发明涉及2-甲基-6-苯基苯醌基甲基转移酶及其功能等同物在鉴定除草或生长调节化合物的方法中的用途，以及通过该方法鉴定的化合物作为除草剂或生长调节剂的用途 。

公开(公告)号：US20060058190A1

公开(公告)日：2006-03-16

申请号：US10538544

申请日：2003-12-17

申请人： Thomas Ehrhardt ,  Andreas Reindl ,  Annette Freund ,  Ralf-Michael Schmidt ,  Kirsten Deist ,  Uwe Sonnewald ,  Marc Nigel ,  Wolfgang Lein ,  Frederik Bornke

发明人： Thomas Ehrhardt ,  Andreas Reindl ,  Annette Freund ,  Ralf-Michael Schmidt ,  Kirsten Deist ,  Uwe Sonnewald ,  Marc Nigel ,  Wolfgang Lein ,  Frederik Bornke

IPC分类号： A01N25/00 ,  C12Q1/48

CPC分类号： C12N9/0006 ,  C12N15/8274 ,  C12Q1/32

摘要： The present invention relates to malate dehydrogenase, which, when absent, brings about reduced growth and chlorotic leaves and is encoded by the nucleic acid sequence SEQ ID NO:2 or by a functional equivalent of this nucleic acid sequence, as target for herbicides. For this purpose, novel nucleic acid sequences encompassing SEQ ID NO:2 and functional equivalents of SEQ ID NO:2 are provided. Moreover, the present invention relates to the use of the abovementioned malate dehydrogenase and its functional equivalents in a method for identifying compounds with herbicidal or growth-regulatory activity, and to the use of the compounds identified by this method as herbicides or growth regulators.

摘要翻译： 本发明涉及苹果酸脱氢酶，当不存在时，其产生减少的生长和褪绿叶，并由核酸序列SEQ ID NO：2编码，或通过该核酸序列的功能等同物作为除草剂的靶标。 为此，提供了包含SEQ ID NO：2和SEQ ID NO：2的功能等同物的新型核酸序列。 此外，本发明涉及上述苹果酸脱氢酶及其功能等同物在鉴定具有除草或生长调节活性的化合物的方法中的用途，以及通过该方法鉴定的化合物作为除草剂或生长调节剂的用途。

公开(公告)号：US20050142553A1

公开(公告)日：2005-06-30

申请号：US10507989

申请日：2003-03-13

申请人： Uwe Sonnewald ,  Frederik Bornke ,  Kirsten Deist ,  Marc Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

发明人： Uwe Sonnewald ,  Frederik Bornke ,  Kirsten Deist ,  Marc Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

IPC分类号： A01H1/00 ,  A01H5/00 ,  A01K67/027 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/10 ,  C12N15/09 ,  C12N15/82 ,  C12Q1/02 ,  C12Q1/48 ,  C12Q1/68 ,  A01N25/00 ,  C12N9/24 ,  G01N33/48 ,  G01N33/50 ,  G06F19/00

CPC分类号： C12N9/1014 ,  C12N15/8274

摘要： The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.

摘要翻译： 本发明涉及丝氨酸羟甲基转移酶（EC 2.1.2.1）作为除草剂的新靶标，以及编码具有丝氨酸羟甲基转移酶生物活性的多肽的核酸序列，当不存在时，其产生生长迟缓症状和褪绿叶 包括核酸序列SEQ ID No：3和上述核酸序列或核酸序列SEQ ID NO：7的功能等同物和上述核酸序列的功能等同物。 此外，本发明涉及上述核酸序列，SEQ ID NO：3或SEQ ID NO：7的功能类似物或由上述核酸序列之一编码的多肽在除草方法中的用途 抑制丝氨酸羟甲基转移酶的活性化合物，以及通过该方法鉴定的这些化合物作为除草剂的用途。

公开(公告)号：US06229067B1

公开(公告)日：2001-05-08

申请号：US09284418

申请日：1999-04-14

申请人： Uwe Sonnewald ,  Marcus Ebneth ,  Ralf-Michael Schmidt

发明人： Uwe Sonnewald ,  Marcus Ebneth ,  Ralf-Michael Schmidt

IPC分类号： C12N504

CPC分类号： C12N15/8225 ,  C12N15/8222 ,  C12N15/8234

摘要： The present invention relates to promoters which cause, in plants, permanent leaf-specific expression of an encoding nucleotide sequence under the control of said promoters, for example a sequence which imparts resistance or an increase in the photosynthetic performance.

摘要翻译： 本发明涉及在植物中引起编码核苷酸序列在所述启动子控制下的永久性叶特异性表达的启动子，例如赋予抗性或增加光合性能的序列。

公开(公告)号：US20110113494A1

公开(公告)日：2011-05-12

申请号：US12645976

申请日：2009-12-23

申请人： Uwe Sonnewald ,  Frederik Börnke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

发明人： Uwe Sonnewald ,  Frederik Börnke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

IPC分类号： A61K49/00 ,  C40B30/04 ,  A01H5/00 ,  A01K67/00 ,  C12N1/19 ,  C12N1/15 ,  C12N1/21 ,  C12Q1/68 ,  G01N33/573 ,  C12Q1/02 ,  C40B30/06 ,  A01H1/06

CPC分类号： C12N9/1014 ,  C12N15/8274

摘要： The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.

摘要翻译： 本发明涉及丝氨酸羟甲基转移酶（EC 2.1.2.1）作为除草剂的新靶标，以及编码具有丝氨酸羟甲基转移酶生物活性的多肽的核酸序列，当不存在时，其产生生长迟缓症状和褪绿叶 包括核酸序列SEQ ID No：3和上述核酸序列或核酸序列SEQ ID NO：7的功能等同物和上述核酸序列的功能等同物。 此外，本发明涉及上述核酸序列，SEQ ID NO：3或SEQ ID NO：7的功能类似物或由上述核酸序列之一编码的多肽在除草方法中的用途 抑制丝氨酸羟甲基转移酶的活性化合物，以及通过该方法鉴定的这些化合物作为除草剂的用途。

公开(公告)号：US07662603B2

公开(公告)日：2010-02-16

申请号：US11949874

申请日：2007-12-04

申请人： Uwe Sonnewald ,  Frederik Boernke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

发明人： Uwe Sonnewald ,  Frederik Boernke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

IPC分类号： C12N9/00 ,  C12N9/10 ,  C12N1/20 ,  C12N15/00 ,  C07H21/04

CPC分类号： C12N9/1014 ,  C12N15/8274

摘要： The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.

摘要翻译： 本发明涉及丝氨酸羟甲基转移酶（EC 2.1.2.1）作为除草剂的新靶标，以及编码具有丝氨酸羟甲基转移酶生物活性的多肽的核酸序列，当不存在时，其产生生长迟缓症状和褪绿叶 包括核酸序列SEQ ID No：3和上述核酸序列或核酸序列SEQ ID NO：7的功能等同物和上述核酸序列的功能等同物。 此外，本发明涉及上述核酸序列，SEQ ID NO：3或SEQ ID NO：7的功能类似物或由上述核酸序列之一编码的多肽在除草方法中的用途 抑制丝氨酸羟甲基转移酶的活性化合物，以及通过该方法鉴定的这些化合物作为除草剂的用途。