Abstract:
Devices, systems, and methods for delivering fluid are provided. Devices include a housing configured for intravaginal deployment and retention, at least one reservoir configured to contain a fluid, and a fluid dispensing mechanism configured to dispense the fluid past the cervix and to the uterus of the subject. Methods include intravaginally deploying and retaining a device in the subject, and dispensing the fluid from the device such that the fluid is driven past the cervix to the uterus of the subject.
Abstract:
A neutron detector that utilizes cells in which a liquid scintillator is contained in elongated detector tubes, with photo-detectors disposed at each end of the tube to measure scintillation light generated by incident neutrons. The liquid scintillator is an interblended mixture including an ionic liquid blended with a scintillation enhancer and/or a moderator and/or a controlled optical attenuator. A longitudinal position of an incident neutron is determined by the magnitudes of the scintillation light portions arriving at each photo-detector, which are proportional to the distances between the neutron interaction point and the photo-detectors. The cells are arranged in a closely-spaced parallel planar array to facilitate determining incident neutron location in two dimensions. A detector system utilizes a first detector array to detect fast neutrons, a thermalizer (e.g., polyethylene) to convert fast incident neutrons to thermal neutrons, and a second detector array to detect the thermal neutrons.
Abstract:
Devices, systems, and methods for detecting estrus in subjects are provided. Devices include a housing configured for intravaginal/intrauterine deployment and retention and a sensor disposed in or on the housing, and are configured to use condition information sensed by the sensor to determine an estrus condition of the subject. Methods include deploying a device in the subject, sensing the condition information, and determining an estrus condition using the condition information. Systems include a device configured to communicate with a base station and/or with other implanted devices, which are located within a reception radius thereof, regarding the determined estrus condition.
Abstract:
Embodiments are directed to a host structure that includes a waveguide configured to deliver measurement light to a compartment at least partially within the host structure. The compartment is configured to reversibly engage a fluidic optical cartridge. The host structure also includes a detector configured to receive and process output light emanating from the fluidic optical cartridge as well as electronics to process signals from the detector.
Abstract:
Retention devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and at least one reservoir contained within the housing. The at least one reservoir may have an actuation end and a release end and contain at least one drug formulation. A plug may be contained within the at least one reservoir and be moveable from the actuation end toward the release end. The device may also include an actuation system operably connected to the actuation end of the at least one reservoir and configured to drive the at least one drug formulation from the reservoir. The device may also include at least one retention member affixed to the housing and movable between a non-stressed position, a deployment position, and a retention position for retaining the device in an intraluminal location in the subject.
Abstract:
A method of joining fiberglass-reinforced composite pipes includes joining an inner tube of each pipe by fusion to form a fused bond, joining fiber reinforced polymer tubes of each pipe by depositing a silica glass particle epoxy directly on the fused bond and on bonded edges of the fiber reinforced polymer tubes as a composition to cover tube edges and the fused inner tube bond, and curing the composition.
Abstract:
Retention devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and at least one reservoir contained within the housing. The at least one reservoir may have an actuation end and a release end and contain at least one drug formulation. A plug may be contained within the at least one reservoir and be moveable from the actuation end toward the release end. The device may also include an actuation system operably connected to the actuation end of the at least one reservoir and configured to drive the at least one drug formulation from the reservoir. The device may also include at least one retention member affixed to the housing and movable between a non-stressed position, a deployment position, and a retention position for retaining the device in an intraluminal location in the subject.
Abstract:
Devices, systems, and methods for detecting estrus in subjects are provided. Devices include a housing configured for intravaginal/intrauterine deployment and retention and a sensor disposed in or on the housing, and are configured to use condition information sensed by the sensor to determine an estrus condition of the subject. Methods include deploying a device in the subject, sensing the condition information, and determining an estrus condition using the condition information. Systems include a device configured to communicate with a base station and/or with other implanted devices, which are located within a reception radius thereof, regarding the determined estrus condition.
Abstract:
Devices, systems, and methods for delivering fluid are provided. Devices include a housing configured for intravaginal deployment and retention, at least one reservoir configured to contain a fluid, and a fluid dispensing mechanism configured to dispense the fluid past the cervix and to the uterus of the subject. Methods include intravaginally deploying and retaining a device in the subject, and dispensing the fluid from the device such that the fluid is driven past the cervix to the uterus of the subject.
Abstract:
A neutron detector that utilizes cells in which a liquid scintillator is contained in elongated detector tubes, with photo-detectors disposed at each end of the tube to measure scintillation light generated by incident neutrons. The liquid scintillator is an interblended mixture including an ionic liquid blended with a scintillation enhancer and/or a moderator and/or a controlled optical attenuator. A longitudinal position of an incident neutron is determined by the magnitudes of the scintillation light portions arriving at each photo-detector, which are proportional to the distances between the neutron interaction point and the photo-detectors. The cells are arranged in a closely-spaced parallel planar array to facilitate determining incident neutron location in two dimensions. A detector system utilizes a first detector array to detect fast neutrons, a thermalizer (e.g., polyethylene) to convert fast incident neutrons to thermal neutrons, and a second detector array to detect the thermal neutrons.