公开(公告)号：US20050016300A1

公开(公告)日：2005-01-27

申请号：US10495115

申请日：2002-11-19

申请人： Per Mansson ,  Jan Smith ,  Ann-Charlotte Hellgren

发明人： Per Mansson ,  Jan Smith ,  Ann-Charlotte Hellgren

IPC分类号： G01N1/22 ,  G01N1/00 ,  G01N1/36 ,  G01N1/38 ,  G01N1/40 ,  G01N1/44

CPC分类号： G01N1/40 ,  G01N2001/2282 ,  G01N2001/383 ,  G01N2001/4033

摘要： An apparatus (10) and a method for concentrating and transferring volatile compounds contained in a sample on a detachable solid support (12) into a liquid for subsequent detection and/or analysis of the volatile compounds, are described. The apparatus comprises a holder (14) for the solid support (12), means (16) for transporting the holder (14) to a heating position on a heatable plate (18), a closed room-creating arrangement comprising the heatable plate (18) attached to a movable housing (30), the holder (14), the solid support (12), a funnel (20) on the solid support (12), and inside the funnel (20) a cold spot (22), means inside the housing (30) for heating the heatable plate (18) to evaporate the volatile compounds which then are condensed on the cold spot (22), means (24) for transporting the cold spot (22) from a cooler (26) to the inside of the funnel (20) and from there to a position (28) where condensed compounds are removed from the cold spot (22) into a liquid.

摘要翻译： 描述了用于将包含在样品中的挥发性化合物浓缩并转移到可分离的固体支持物（12）上的装置（10）和用于随后检测和/或分析挥发性化合物的液体的方法。 该设备包括用于固体支撑件（12）的保持器（14），用于将保持器（14）运送到可加热板（18）上的加热位置的装置（16），包括可加热板 18），固定支架（12），固体支撑件（12）上的漏斗（20），漏斗（20）内的冷点（22）， ，用于加热可加热板（18）以蒸发在冷点（22）上冷凝的挥发性化合物的装置（30）内的装置，用于将冷点（22）从冷却器（26）输送的装置 ）到漏斗（20）的内部并从那里到达冷凝化合物从冷点（22）去除成液体的位置（28）。

公开(公告)号：US07089812B2

公开(公告)日：2006-08-15

申请号：US10495115

申请日：2002-11-19

申请人： Per Månsson ,  Jan Smith ,  Ann-Charlotte Hellgren

发明人： Per Månsson ,  Jan Smith ,  Ann-Charlotte Hellgren

IPC分类号： G01N1/40

CPC分类号： G01N1/40 ,  G01N2001/2282 ,  G01N2001/383 ,  G01N2001/4033

摘要： An apparatus (10) and a method for concentrating and transferring volatile compounds contained in a sample on a detachable solid support (12) into a liquid for subsequent detection and/or analysis of the volatile compounds, are described. The apparatus comprises a holder (14) for the solid support (12), means (16) for transporting the holder (14) to a heating position on a heatable plate (18), an enclosed space-creating arrangement comprising the heatable plate (18) attached to a movable housing (30), the holder (14), the solid support (12), a funnel (20) on the solid support (12), and inside the funnel (20) a chilled member (22), means inside the housing (30) for heating the heatable plate (18) to evaporate the volatile compounds which then are condensed on the chilled member (22), means (24) for transporting the chilled member (22) from a cooler (26) to the inside of the funnel (20) and from there to a position (28) where condensed compounds are removed from the chilled member (22) into a liquid.

摘要翻译： 描述了用于将包含在样品中的挥发性化合物浓缩并转移到可分离的固体支持物（12）上的装置（10）和用于随后检测和/或分析挥发性化合物的液体的方法。 该装置包括用于固体支撑件（12）的保持器（14），用于将保持器（14）运送到可加热板（18）上的加热位置的装置（16），包括可加热板 18），固定支架（12），固体支撑件（12）上的漏斗（20），以及漏斗（20）内部的冷却部件（22）， ，用于加热所述可加热板（18）以蒸发所述挥发性化合物的装置（30），所述挥发性化合物然后冷凝在所述冷冻构件（22）上，用于将冷冻构件（22）从冷却器（26）输送的装置 ）到漏斗（20）的内部并且从那里到达冷凝的化合物从冷冻构件（22）移除到液体中的位置（28）。

公开(公告)号：US20060014270A1

公开(公告)日：2006-01-19

申请号：US10517321

申请日：2003-06-18

申请人： Per Mansson ,  Henrik Andersson ,  Jan Smith ,  Kjeld Jensen ,  Teodor Aastrup

发明人： Per Mansson ,  Henrik Andersson ,  Jan Smith ,  Kjeld Jensen ,  Teodor Aastrup

IPC分类号： C12M1/34

CPC分类号： G01N35/1097 ,  G01N5/02 ,  G01N29/036 ,  G01N33/946 ,  G01N2291/106

摘要： A system, device and method for detection of several individual analytes in a test solution aliquot (83) with an array of individually operated piezoelectric crystal microbalances are described. The system comprises a connecting station (100) that receives a plurality of individually specific piezoelectric crystal microbalance flow-trough cells (10), each containing a piezoelectric crystal (50) carrying electrodes (56,62) and a coating (66,46) exposing a first member of an interaction pair specific for an individual analyte being a second member of the interaction pair. Flowing means (70) flows a solution (75) and the test solution aliquot (83) to and through a cell compartment of each of the cells (10) via the connecting station (100). Power and measurement means (130) oscillate the piezoelectric crystal(s) (50). A change in oscillating characteristics of the crystal(s) (50), following interaction between the first and second members of the interaction pair, detects presence of the individual analyte(s). Further, disposable flow cells (10) for use in an array of individually operated piezoelectric crystal microbalances (112) is described.

摘要翻译： 描述了具有独立操作的压电晶体微量平衡阵列的测试溶液等分试样（83）中检测几种单独分析物的系统，装置和方法。 该系统包括接收多个单独特定的压电晶体微量天平流槽电池（10）的连接站（100），每个单元包含承载电极（56,62）和涂层（66,46）的压电晶体（50） 暴露对于作为相互作用对的第二成员的单个分析物特异性的相互作用对的第一成员。 流动装置（70）通过连接站（100）将溶液（75）和测试溶液等分试样（83）流经并通过每个电池（10）的电池室。 功率和测量装置（130）振荡压电晶体（50）。 在相互作用对的第一和第二成员之间的相互作用之后，晶体（50）的振荡特性的变化检测各个分析物的存在。 此外，描述了用于独立操作的压电晶体微量平衡阵列（112）的一次性流通池（10）。

公开(公告)号：US20060129080A1

公开(公告)日：2006-06-15

申请号：US11009429

申请日：2004-12-10

申请人： Sten Bjornberg ,  Jan Smith

发明人： Sten Bjornberg ,  Jan Smith

IPC分类号： A61F15/00 ,  A61F13/00

CPC分类号： A61F13/00063 ,  A61F13/00042 ,  A61F2013/00182 ,  A61F2013/00263 ,  A61F2013/00412 ,  A61F2013/00582 ,  A61F2013/00604 ,  A61F2013/00727 ,  A61F2013/00846 ,  A61F2013/00876 ,  A61L15/44 ,  A61L15/46 ,  A61L15/58

摘要： A wound dressing product, combining both a traditional dressing with a mounted absorbent material and a hydrophobic fabric attached thereto, which is to be placed towards the wound, and is capable of binding unwanted microorganisms. The wound dressing product protects the wound, absorbs exudate and reduces the number of pathogenic microorganisms, without using antimicrobial substances, and consists of three bonded layers: hydrophobic cellulose acetate fabric which binds microorganisms, an attached efficient absorbent material, and a backing (cover) which is preferably visually transparent, semi-permeable and self-adhesive.

公开(公告)号：US20060141608A1

公开(公告)日：2006-06-29

申请号：US10539065

申请日：2003-12-18

申请人： Teodor Aastrup ,  Jan Smith ,  Henrik Anderson

发明人： Teodor Aastrup ,  Jan Smith ,  Henrik Anderson

IPC分类号： C12M1/34

CPC分类号： G01N29/036 ,  G01N2291/0256

摘要： A piezoelectric sensor arrangement for analysis of fluid samples includes a signal source, a measuring device and a docking system. The sensor arrangement comprises a first part provided with means for receiving a sensor element that exposes a piezoelectric quartz crystal, a second part comprising fluid channels for the sample and a flow cell element, which preferably is removable and which comprises a recess, and inlet and outlet fluid channels for leading a fluid through the recess. The first and second parts are movable in relation to each other between a closed position and an open position and are arranged such that in the closed position the recess of the flow cell element is sealingly covered by the piezoelectric quartz crystal so that a flow cell is formed by said flow cell element and the quartz crystal.

摘要翻译： 用于分析流体样品的压电传感器装置包括信号源，测量装置和对接系统。 该传感器装置包括：第一部分，其设置有用于接收暴露压电石英晶体的传感器元件的装置;第二部分包括用于样品的流体通道;以及流动池元件，其优选地是可移除的并且包括凹槽， 出口流体通道，用于引导流体通过凹槽。 第一和第二部分可以在关闭位置和打开位置之间相对于彼此移动，并且被布置成使得在关闭位置中，流动电池元件的凹部被压电石英晶体密封地覆盖，使得流动池是 由所述流动池元件和石英晶体形成。

公开(公告)号：US20060107733A1

公开(公告)日：2006-05-25

申请号：US10542616

申请日：2004-02-11

申请人： Teodor Aastrup ,  Jan Smith ,  Henrik Anderson

发明人： Teodor Aastrup ,  Jan Smith ,  Henrik Anderson

IPC分类号： G01N29/02

CPC分类号： H03H9/132 ,  G01N9/002 ,  G01N11/16 ,  G01N29/022 ,  G01N29/036 ,  G01N29/222 ,  G01N2291/0256 ,  G01N2291/02818 ,  G01N2291/0421 ,  G01N2291/0422 ,  H03H9/19

摘要： A piezoelectric resonator for use in a sensor arrangement for detecting or measuring an analyte in a medium, comprises a quartz crystal plate, face. The first crystal surface is provided with a first electrode, which has a surface area of less than 15 mm2 and the second crystal surface is provided with a second electrode. The first electrode may have a rectangular surface shape. A flow cell for use in an apparatus for detecting or measuring an analyte in a medium, comprises walls that form a sensing chamber together with the resonator, and inlet and outlet openings for leading a fluid through the sensing chamber. A part of the resonator constitutes one of the walls of the sensing chamber and is arranged such that the first electrode is situated inside the sensing chamber.

摘要翻译： 用于检测或测量介质中的分析物的传感器装置中的压电谐振器包括石英晶片，面。 第一晶体表面设置有表面积小于15mm 2的第一电极，第二晶体表面设置有第二电极。 第一电极可以具有矩形表面形状。 用于检测或测量介质中的分析物的装置中的流动池包括与谐振器一起形成检测室的壁和用于引导流体通过感测室的入口和出口。 谐振器的一部分构成感测室的一个壁，并且被布置为使得第一电极位于感测室内。

公开(公告)号：US07771657B2

公开(公告)日：2010-08-10

申请号：US10517321

申请日：2003-06-18

申请人： Per Månsson ,  Henrik Andersson ,  Jan Smith ,  Kjeld Jensen ,  Teodor Aastrup

发明人： Per Månsson ,  Henrik Andersson ,  Jan Smith ,  Kjeld Jensen ,  Teodor Aastrup

IPC分类号： G01N21/00 ,  G01N27/00 ,  G01N31/00 ,  G01N33/22 ,  G01N33/53 ,  G01N33/567 ,  C12Q1/00 ,  C12Q1/68

CPC分类号： G01N35/1097 ,  G01N5/02 ,  G01N29/036 ,  G01N33/946 ,  G01N2291/106

摘要： A system, device and method for detection of several individual analytes in a test solution aliquot (83) with an array of individually operated piezoelectric crystal microbalances are described. The system comprises a connecting station (100) that receives a plurality of individually specific piezoelectric crystal microbalance flow-trough cells (10), each containing a piezoelectric crystal (50) carrying electrodes (56,62) and a coating (66,46) exposing a first member of an interaction pair specific for an individual analyte being a second member of the interaction pair. Flowing means (70) flows a solution (75) and the test solution aliquot (83) to and through a cell compartment of each of the cells (10) via the connecting station (100). Power and measurement means (130) oscillate the piezoelectric crystal(s) (50). A change in oscillating characteristics of the crystal(s) (50), following interaction between the first and second members of the interaction pair, detects presence of the individual analyte(s). Further, disposable flow cells (10) for use in an array of individually operated piezoelectric crystal microbalances (112) is described.

摘要翻译： 描述了具有独立操作的压电晶体微量平衡阵列的测试溶液等分试样（83）中检测几种单独分析物的系统，装置和方法。 该系统包括接收多个单独特定的压电晶体微量天平流槽电池（10）的连接站（100），每个单元包含承载电极（56,62）和涂层（66,46）的压电晶体（50） 暴露对于作为相互作用对的第二成员的单个分析物特异性的相互作用对的第一成员。 流动装置（70）通过连接站（100）将溶液（75）和测试溶液等分试样（83）流经并通过每个电池（10）的电池室。 功率和测量装置（130）振荡压电晶体（50）。 在相互作用对的第一和第二成员之间的相互作用之后，晶体（50）的振荡特性的变化检测各个分析物的存在。 此外，描述了用于独立操作的压电晶体微量平衡阵列（112）的一次性流通池（10）。

公开(公告)号：USD489319S1

公开(公告)日：2004-05-04

申请号：US29166236

申请日：2002-08-23

申请人： Per Månsson ,  Kjeld Jensen ,  Teodor Aastrup ,  Henrik Andersson ,  Jan Smith

设计人： Per Månsson ,  Kjeld Jensen ,  Teodor Aastrup ,  Henrik Andersson ,  Jan Smith

公开(公告)号：US09762204B2

公开(公告)日：2017-09-12

申请号：US13329894

申请日：2011-12-19

申请人： Teodor Aastrup ,  Jan Smith ,  Henrik Anderson

发明人： Teodor Aastrup ,  Jan Smith ,  Henrik Anderson

IPC分类号： H03H9/13 ,  G01N9/00 ,  G01N11/16 ,  G01N29/02 ,  G01N29/036 ,  G01N29/22 ,  H03H9/19

CPC分类号： H03H9/132 ,  G01N9/002 ,  G01N11/16 ,  G01N29/022 ,  G01N29/036 ,  G01N29/222 ,  G01N2291/0256 ,  G01N2291/02818 ,  G01N2291/0421 ,  G01N2291/0422 ,  H03H9/19

摘要： A piezoelectric resonator for use in a sensor arrangement for detecting or measuring an analyte in a medium, comprises a quartz crystal plate, having a first crystal surface and a second crystal surface. The first crystal surface is provided with a first electrode, which has a surface area of less than 15 mm2 and the second crystal surface is provided with a second electrode. The first electrode may have a rectangular surface shape. A flow cell for use in an apparatus for detecting or measuring an analyte in a medium, comprises walls that form a sensing chamber together with the resonator, and inlet and outlet openings for leading a fluid through the sensing chamber. A part of the resonator constitutes one of the walls of the sensing chamber and is arranged such that the first electrode is situated inside the sensing chamber.

公开(公告)号：US08591812B2

公开(公告)日：2013-11-26

申请号：US10539065

申请日：2003-12-18

申请人： Teodor Aastrup ,  Jan Smith ,  Henrik Anderson

发明人： Teodor Aastrup ,  Jan Smith ,  Henrik Anderson

IPC分类号： G01N11/16

CPC分类号： G01N29/036 ,  G01N2291/0256

摘要： A piezoelectric sensor arrangement for analysis of fluid samples includes a signal source, a measuring device and a docking system. The sensor arrangement comprises a first part capable of receiving a sensor element that exposes a piezoelectric quartz crystal, a second part comprising fluid channels for the sample and a flow cell element, which preferably is removable and which comprises a recess, and inlet and outlet fluid channels for leading a fluid through the recess. The first and second parts are movable in relation to each other between a closed position and an open position and are arranged such that in the closed position the recess of the flow cell element is sealingly covered by the piezoelectric quartz crystal so that a flow cell is formed by the flow cell element and the quartz crystal.

摘要翻译： 用于分析流体样品的压电传感器装置包括信号源，测量装置和对接系统。 传感器装置包括能够接收暴露压电石英晶体的传感器元件的第一部分，包括用于样品的流体通道的第二部分和流动元件，其优选地是可移除的并且包括凹部，以及入口和出口流体 用于引导流体通过凹槽的通道。 第一和第二部分可以在关闭位置和打开位置之间相对于彼此移动，并且被布置成使得在关闭位置中，流动电池元件的凹部被压电石英晶体密封地覆盖，使得流动池是 由流动池元件和石英晶体形成。