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    SYSTEMS AND METHODS FOR MESO-DISSECTION
    2.
    发明申请
    SYSTEMS AND METHODS FOR MESO-DISSECTION 审中-公开

    公开(公告)号：US20170322124A1

    公开(公告)日：2017-11-09

    申请号：US15659566

    申请日：2017-07-25

    申请人： ROCHE SEQUENCING SYSTEMS, INC.

    发明人： Michael Barnes ,  Srinivas Chukka ,  Mohammad Qadri

    IPC分类号： G01N1/28 ,  G06T7/00 ,  G06T7/33 ,  G01N1/38

    CPC分类号： G01N1/286 ,  G01N2001/2873 ,  G01N2001/383 ,  G01N2800/00 ,  G06T7/0014 ,  G06T7/33 ,  G06T2207/10056 ,  G06T2207/30024

    摘要： The subject disclosure provides systems, computer-implemented methods, and clinical workflows for meso-dissection of biological specimens and tissue slides by incorporating annotation and inter-marker registration modules within digital pathology imaging and meso-dissection (or milling) systems. Images of a reference slide a milling slide may be acquired using the same imaging system, with the annotations on the image associated with the milling slide being based on the inter-marker registration. Each image along with its respective annotations and meta-data may be associated with a project or a case, and stored in an image management system. A same-marker registration may be used to map annotations from the annotated image of the milling slide to a live image of the milling slide. The milling slide may be milled based on the annotations, with milled tissue output into a contained that is labeled in association with the labeled input slides.

    Semi-dry type electrostatic cyclone sampler and method for sampling gas and/or water sample
    3.
    发明授权
    Semi-dry type electrostatic cyclone sampler and method for sampling gas and/or water sample 有权

    公开(公告)号：US09671320B2

    公开(公告)日：2017-06-06

    申请号：US14831574

    申请日：2015-08-20

    申请人： JUSUN INSTRUMENTS CO., LTD.

    发明人： Jonathan Yang ,  Chuen-Jinn Tsai

    IPC分类号： G01N1/22 ,  G01N1/38

    CPC分类号： G01N1/2202 ,  G01N1/2211 ,  G01N1/38 ,  G01N2001/383

    摘要： A semi-dry type electrostatic cyclone sampler includes a cyclone body, an insulate element, a discharge electrode, an air tube, an air introducing means, a discharging means and a flushing means. The insulate element is disposed at a top of the cyclone body and co-defines a cyclone chamber with the cyclone body. The discharging electrode is disposed on the insulate element. The air tube is disposed at a bottom of the cyclone body. The air introducing means is for introducing a particulate-containing air stream into the cyclone chamber. The discharging means is for charging the particulates so that the particulates can attach to an inside of the cyclone body. The flushing means is for flushing the inside of the cyclone body and collecting part of the particulates. When the discharging means activates, the air introducing means activates simultaneously. When the flushing means activates, the discharging means is deactivated.

    MICROFLUIDIC SERIAL DILUTION PLATFORM BASED WELL-PLATE USING AN OIL-FREE IMMISCIBLE PHASE DRIVEN BY MANUAL OR ELECTRONIC PIPETTORS
    4.
    发明申请
    MICROFLUIDIC SERIAL DILUTION PLATFORM BASED WELL-PLATE USING AN OIL-FREE IMMISCIBLE PHASE DRIVEN BY MANUAL OR ELECTRONIC PIPETTORS 审中-公开
    使用手动或电子管驱动的无油无油相的微流控系列平板式平板

    公开(公告)号：US20160214108A1

    公开(公告)日：2016-07-28

    申请号：US15005341

    申请日：2016-01-25

    申请人： Neofluidics LLC

    发明人： Deepak Solomon ,  Nilesh Gupta

    IPC分类号： B01L3/00 ,  G01N1/38

    CPC分类号： B01L3/502715 ,  B01F13/0083 ,  B01F15/0404 ,  B01L2200/0605 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0864 ,  B01L2300/0883 ,  B01L2400/0406 ,  B01L2400/0688 ,  G01N1/38 ,  G01N2001/383

    摘要： Described is a microfluidic serial dilution platform based well-plate using an oil-free immiscible phase driven by manual or electronic pipettors. The well-plate includes a plurality of fluidic traps, a plurality of hydrophilic capillary constriction channels and a plurality of bypass channels. Each of the plurality of bypass channels is associated with one of the plurality of fluidic traps, each of the plurality of hydrophilic capillary constriction channels is associated with one of the plurality of fluidic traps, and each of the plurality of fluidic traps is associated with one of the plurality of bypass channels and one of the plurality of hydrophilic capillary constriction channels. The well-plate further includes an inlet, an outlet, and a main channel with a plurality of portions that connects the inlet to the plurality of fluidic traps, associated hydrophilic capillary constriction channels and associated bypass channels, and the outlet.

    摘要翻译： 描述了一种基于微流控系列稀释平台的平板，使用由手动或电子移液器驱动的无油不混溶相。 井板包括多个流体捕集器，多个亲水性毛细收缩通道和多个旁通通道。 多个旁路通道中的每一个与多个流体捕集器中的一个相关联，多个亲水性毛细收缩通道中的每一个与多个流体捕集器中的一个相关联，并且多个流体捕集器中的每一个与一个流体捕集器中的一个相关联 的多个旁路通道中的一个和多个亲水性毛细收缩通道中的一个。 井板还包括入口，出口和主通道，其具有将入口连接到多个流体捕集器，相关联的亲水性毛细收缩通道和相关联的旁路通道的多个部分以及出口。

    Device and Methods
    5.
    发明申请
    Device and Methods 审中-公开
    设备和方法

    公开(公告)号：US20160153878A1

    公开(公告)日：2016-06-02

    申请号：US14765247

    申请日：2014-02-04

    申请人： EPONA BIOTECH LTD

    发明人： Ruth Candon ,  Heinrich Anhold ,  Di-Sien Chan

    IPC分类号： G01N1/38 ,  B01L3/02 ,  G01N33/68

    CPC分类号： G01N1/38 ,  B01L3/0203 ,  B01L3/0241 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/0689 ,  B01L2300/0838 ,  B01L2300/161 ,  G01N33/543 ,  G01N33/558 ,  G01N33/6893 ,  G01N2001/383 ,  G01N2333/75 ,  G01N2333/775 ,  G01N2333/91188 ,  G01N2333/9123 ,  G01N2800/40 ,  Y02A50/57

    摘要： The present invention relates generally to methods and materials pertaining to assays, for example immunoassays, for biomarkers in body fluids e.g. blood. The invention also relates to diagnostic or screening methods for infections, and methods of differentiating between infectious and non-infectious conditions in mammals, particularly equines, for monitoring response to anti-infective/antibiotic therapy. The invention further relates to a test fluid collection system adapted to permit dilution and analysis of the collected test fluid. The invention further relates to monitoring exertional rhabdomyolysis in equines, and assay devices for all these things.

    摘要翻译： 本发明一般涉及关于测定的方法和材料，例如免疫测定，用于体液中的生物标志物。 血液。 本发明还涉及用于感染的诊断或筛选方法，以及区分哺乳动物，特别是马中的感染性和非感染性病症之间用于监测对抗感染/抗生素治疗的应答​​的方法。 本发明还涉及适于允许对所收集的测试流体进行稀释和分析的测试流体收集系统。 本发明还涉及监测马的运动性横纹肌溶解，以及所有这些事情的测定装置。

    Extraction system
    6.
    发明授权
    Extraction system 有权
    提取系统

    公开(公告)号：US08975085B2

    公开(公告)日：2015-03-10

    申请号：US13058828

    申请日：2009-08-06

    申请人： Jonathan Spencer Howells ,  Kevin Deane

    发明人： Jonathan Spencer Howells ,  Kevin Deane

    IPC分类号： G01N1/38 ,  G01N1/40 ,  B01F1/00 ,  B01F5/10 ,  B01F11/02 ,  B01F15/04 ,  B01F15/00 ,  G01N35/00

    CPC分类号： B01F1/0027 ,  B01F1/0038 ,  B01F5/10 ,  B01F11/0266 ,  B01F11/0283 ,  B01F15/00123 ,  B01F15/0437 ,  B01F2001/0061 ,  G01N1/38 ,  G01N1/4055 ,  G01N2001/383 ,  G01N2001/4061 ,  G01N2035/00554 ,  Y10T436/25

    摘要： An extraction system for distributing a test product in an extraction fluid, the system including a flow cell and a pump The flow cell has walls defining an internal passageway having an extraction region for holding the test product and also an upstream end and a downstream end between which the extraction region extends. The internal cross-sectional area of the upstream end is larger than the internal cross-sectional area of the downstream end the and extraction region tapers from the upstream end to the downstream end. The pump has an inlet in fluid communication with the downstream end and an outlet in fluid communication with the upstream end. The pump re-circulates extraction fluid from the downstream end back to the upstream end so as to progressively erode the test product and distribute the test product in the extraction fluid.

    摘要翻译： 一种用于将检测产品分配在提取流体中的提取系统，该系统包括流动池和泵。流动池具有限定内部通道的壁，该内部通道具有用于保持测试产品的提取区域，以及用于保持测试产品的上游端和下游端 提取区域延伸。 上游端的内部横截面积大于下游端的内部横截面积，并且提取区域从上游端到下游端逐渐变细。 泵具有与下游端流体连通的入口和与上游端流体连通的出口。 泵将下游端的萃取液再循环回上游端，以逐渐侵蚀试验产品并将试验产品分配到萃取液中。

    MEASUREMENT CHIP, MICROFLUIDIC DEVICE AND METHOD
    8.
    发明申请
    MEASUREMENT CHIP, MICROFLUIDIC DEVICE AND METHOD 有权
    测量芯片，微流体装置和方法

    公开(公告)号：US20130323125A1

    公开(公告)日：2013-12-05

    申请号：US13985383

    申请日：2012-02-09

    申请人： Steven Charles Deane

    发明人： Steven Charles Deane

    IPC分类号： G01N33/50

    CPC分类号： G01N33/5094 ,  B01L3/5027 ,  B01L2200/0652 ,  B01L2200/10 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/0883 ,  G01N15/1056 ,  G01N2001/383 ,  Y10T29/49117

    摘要： A measurement chip (100) is disclosed for use with a microfluidic resistance network (20) comprising a microfluidic sample preparation stage (34, 38), a sample outlet (42) and a waste outlet (44) both in fluidic communication with said preparation stage. The measurement chip comprises a sample channel (104) for receiving a sample from said sample outlet (42), the sample channel comprising measurement means (120, 130) and having a first fluidic resistance; and a waste channel (114) for receiving a waste stream from said waste outlet (44) and having a second fluidic resistance.

    摘要翻译： 公开了一种与微流体阻力网络（20）一起使用的测量芯片（100），该微流控阻抗网络（20）包括与所述制剂流体连通的微流体样品制备阶段（34,38），样品出口（42）和废物出口（44） 阶段。 测量芯片包括用于从所述样品出口（42）接收样品的样品通道（104），所述样品通道包括测量装置（120,130）并且具有第一流体阻力; 以及用于从所述废物出口（44）接收废物流并具有第二流体阻力的废物通道（114）。

    SYSTEMS AND METHODS FOR LASER ASSISTED SAMPLE TRANSFER TO SOLUTION FOR CHEMICAL ANALYSIS
    9.
    发明申请
    SYSTEMS AND METHODS FOR LASER ASSISTED SAMPLE TRANSFER TO SOLUTION FOR CHEMICAL ANALYSIS 有权
    用于激光辅助样品转移到化学分析方法的系统和方法

    公开(公告)号：US20130298701A1

    公开(公告)日：2013-11-14

    申请号：US13949777

    申请日：2013-07-24

    申请人： University of Tennessee Research Foundation ,  UT-Batelle, LLC

    发明人： Gary J. VAN BERKEL ,  Vilmos KERTESZ ,  Olga S. OVCHINNIKOVA

    IPC分类号： G01N1/22

    CPC分类号： G01N1/04 ,  G01N1/22 ,  G01N1/38 ,  G01N2001/045 ,  G01N2001/383 ,  G01Q30/02 ,  H01J49/0463 ,  H01J49/165

    摘要： Systems and methods are described for laser ablation of an analyte from a specimen and capturing of the analyte in a dispensed solvent to form a testing solution. A solvent dispensing and extraction system can form a liquid microjunction with the specimen. The solvent dispensing and extraction system can include a surface sampling probe. The laser beam can be directed through the surface sampling probe. The surface sampling probe can also serve as an atomic force microscopy probe. The surface sampling probe can form a seal with the specimen. The testing solution including the analyte can then be analyzed using an analytical instrument or undergo further processing.

    摘要翻译： 描述了用于从样品激光烧蚀分析物并在分配的溶剂中捕获分析物以形成测试溶液的系统和方法。 溶剂分配和萃取系统可以与样品形成液体微结构。 溶剂分配和提取系统可以包括表面取样探针。 激光束可以通过表面取样探针引导。 表面采样探头也可以用作原子力显微镜探针。 表面采样探头可以与样品形成密封。 然后可以使用分析仪器分析包括分析物的测试溶液或进行进一步处理。