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公开(公告)号：US11241475B2
公开(公告)日：2022-02-08
申请号：US16306419
申请日：2017-06-27
发明人： Chihiro Suzuki , Utano Nakamura , Mujo Kim
IPC分类号： A61K38/07 , A61K38/04 , C07K5/00 , C07K5/04 , C07K5/10 , A61P19/08 , A61P19/02 , A61K38/08 , A61K9/00
摘要： Provided is an agent for preventing and/or treating osteogenesis imperfecta, osteoporosis and/or osteoarthritis, the agent comprising a peptide consisting of one of the following amino acid sequences: (a) Val-Asn-Pro-Glu-Ser-Glu-Glu-Glu (SEQ ID NO: 1) and (b) Val-Asn-Pro-Glu (SEQ ID NO: 2). The agent of the present invention can be orally ingested, has osteogenic function, and has a preventive and/or healing-promoting effect on bone fractures and is therefore very useful for prevention and/or treatment of osteogenesis imperfecta, osteoporosis and/or osteoarthritis.
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公开(公告)号：US10154684B2
公开(公告)日：2018-12-18
申请号：US15522231
申请日：2015-10-30
发明人： Seiyu Harada , Toshio Nakamura , Mujo Kim
摘要： The present invention provides a hair regrowth promoter comprising an egg-yolk protein hydrolysate as an active ingredient. The egg-yolk protein hydrolysate is a safe ingredient produced from a natural source, and therefore can be widely used in daily consumable products, such as food and drink products, medicaments, animal feeds, and dietary supplements, or as a food additive, etc. The promoter etc. of the present invention can be orally administered and is thus very advantageous.
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公开(公告)号：US20180036350A1
公开(公告)日：2018-02-08
申请号：US15670918
申请日：2017-08-07
发明人： Isafumi Maru , Ji-Yeong An , Sayuri Tanaka , Maya Sakashita , Seiyu Harada , Kazuya Watabe , Masayoshi Aosasa , Mujo Kim , Toshio Nakamura , Utano Nakamura , Hiroaki Iitsuka
IPC分类号： A61K35/57 , A61K38/05 , A61K8/98 , A61K8/64 , A23L33/00 , A61Q19/00 , A61Q19/08 , A23L2/52 , A23C9/123 , A23C19/00 , A61K31/7004 , A61K8/60
CPC分类号： A61K35/57 , A23C9/123 , A23C9/1322 , A23C19/00 , A23C19/093 , A23L2/52 , A23L2/56 , A23L2/60 , A23L33/18 , A23L33/30 , A23V2002/00 , A61K8/60 , A61K8/64 , A61K8/65 , A61K8/735 , A61K8/981 , A61K9/2068 , A61K9/4875 , A61K31/7004 , A61K38/012 , A61K38/014 , A61K38/05 , A61Q19/007 , A61Q19/08 , A23V2250/542
摘要： An agent of the present invention comprising poultry feet or a processed product thereof, preferably a hydrolysate of an extract of poultry feet, promotes hyaluronic acid production, thereby exhibiting excellent effects of preventing or treating a joint disorder, improving skin dryness, wrinkles or skin tension, moisturizing the skin, etc. The agent is thus useful as a medicament, a quasi-drug, a cosmetic product, a food product or an animal feed.
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公开(公告)号：US10538564B2
公开(公告)日：2020-01-21
申请号：US15121471
申请日：2015-02-25
发明人： Chihiro Yamazaki , Ji-Yeong An , Seiyu Harada , Kazuya Watabe , Mujo Kim
IPC分类号： A61K38/04 , A61K38/08 , A61K38/10 , C07K7/04 , C07K7/06 , C07K7/08 , A23L33/18 , C07K14/51 , A61K8/64 , A61K38/00
摘要： The present invention provides a novel peptide having bone formation-promoting effect and chondrocyte growth-promoting effect, in particular, a peptide having osteoblast growth-promoting activity, having 100 amino acid residues or less comprising an amino acid sequence selected from(a) Val-Asn-Pro-Glu-Ser-Glu-Glu-Glu-Asp-Glu-Ser-Ser-Pro-Tyr-Glu (SEQ ID NO: 1),(b) an amino acid sequence derived from the amino acid sequence (a) by conservative substitution or deletion of 1 to 3 amino acids, and(c) an amino acid sequence consisting of at least four contiguous amino acids of the amino acid sequence (a) or (b), ora derivative thereof or a salt thereof.
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5.发明申请公开(公告)号：US20210268053A1
公开(公告)日：2021-09-02
申请号：US17183646
申请日：2021-02-24
发明人： Hiroaki Iitsuka , Sayo Morita , Keita Koga , Atsushi Yamatsu , Mujo Kim , Toma Furuta
IPC分类号： A61K36/185 , A61P3/04 , A23L33/00 , A23L33/105 , A23L25/00 , A23K10/30
摘要： Problem to be solved: An object of the present invention is to provide a novel fat absorption inhibiting agent.
Solution to the problem: The present invention provides a fat absorption inhibiting agent comprising pulverized defatted sesame seeds or a processed product thereof. The present invention also provides a fat absorption inhibiting agent comprising defatted sesame seeds having a 50th percentile particle size of 1 to 200 μm as determined by laser diffraction/scattering and a compressibility index of to 80%. The fat absorption inhibiting agent of the present invention preferably has lipase inhibitory activity. The present invention also provides a food comprising the agent. The present invention also provides defatted sesame seeds having a 50th percentile particle size of 1 to 200 μm as determined by laser diffraction/scattering and a compressibility index of 30 to 80%. The present invention provides a method for inhibiting obesity in a human or animal, the method comprising administering to a human or animal the agent, the food or the defatted sesame seeds.-
公开(公告)号：US20210128640A1
公开(公告)日：2021-05-06
申请号：US17098112
申请日：2020-11-13
发明人： Isafumi Maru , Ji-Yeong An , Sayuri Tanaka , Maya Sakashita , Seiyu Harada , Kazuya Watabe , Masayoshi Aosasa , Mujo Kim , Toshio Nakamura , Utano Nakamura , Hiroaki Iitsuka
IPC分类号： A61K35/57 , A23C19/093 , A61K38/01 , A23C9/13 , A23L2/60 , A61K9/20 , A61K9/48 , A61K8/73 , A23L2/56 , A23L33/18 , A61K8/65 , A23L33/00 , A23C9/123 , A23C19/00 , A23L2/52 , A61K8/60 , A61K8/64 , A61K8/98 , A61K31/7004 , A61K38/05 , A61Q19/00 , A61Q19/08
摘要： An agent of the present invention comprising poultry feet or a processed product thereof, preferably a hydrolysate of an extract of poultry feet, promotes hyaluronic acid production, thereby exhibiting excellent effects of preventing or treating a joint disorder, improving skin dryness, wrinkles or skin tension, moisturizing the skin, etc. The agent is thus useful as a medicament, a quasi-drug, a cosmetic product, a food product or an animal feed.
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公开(公告)号：US20200316161A1
公开(公告)日：2020-10-08
申请号：US16306419
申请日：2017-06-27
发明人： Chihiro Suzuki , Utano Nakamura , Mujo Kim
摘要： Provided is an agent for preventing and/or treating osteogenesis imperfecta, osteoporosis and/or osteoarthritis, the agent comprising a peptide consisting of one of the following amino acid sequences: (a) Val-Asn-Pro-Glu-Ser-Glu-Glu-Glu (SEQ ID NO: 1) and (b) Val-Asn-Pro-Glu (SEQ ID NO: 2). The agent of the present invention can be orally ingested, has osteogenic function, and has a preventive and/or healing-promoting effect on bone fractures and is therefore very useful for prevention and/or treatment of osteogenesis imperfecta, osteoporosis and/or osteoarthritis.
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公开(公告)号：US11179424B2
公开(公告)日：2021-11-23
申请号：US15670918
申请日：2017-08-07
发明人： Isafumi Maru , Ji-Yeong An , Sayuri Tanaka , Maya Sakashita , Seiyu Harada , Kazuya Watabe , Masayoshi Aosasa , Mujo Kim , Toshio Nakamura , Utano Nakamura , Hiroaki Iitsuka
IPC分类号： A61K38/05 , A61K35/57 , A23C19/093 , A61K38/01 , A23C9/13 , A23L2/60 , A61K9/20 , A61K9/48 , A61K8/73 , A23L2/56 , A23L33/18 , A61K8/65 , A23L33/00 , A23C9/123 , A23C19/00 , A23L2/52 , A61K8/60 , A61K8/64 , A61K8/98 , A61K31/7004 , A61Q19/00 , A61Q19/08
摘要： An agent of the present invention comprising poultry feet or a processed product thereof, preferably a hydrolysate of an extract of poultry feet, promotes hyaluronic acid production, thereby exhibiting excellent effects of preventing or treating a joint disorder, improving skin dryness, wrinkles or skin tension, moisturizing the skin, etc. The agent is thus useful as a medicament, a quasi-drug, a cosmetic product, a food product or an animal feed.
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公开(公告)号：US10034911B2
公开(公告)日：2018-07-31
申请号：US14412770
申请日：2013-07-04
发明人： Mujo Kim , Kazuya Watabe , Jiyeong An , Masayoshi Aosasa , Noriko Horie , Kazuyuki Masuda , Katsuhito Asai
CPC分类号： A61K38/012 , A23L33/18 , A61K38/02 , C12P21/06 , C12Y304/00
摘要： The present invention provides a novel active ingredient which can be safely used in preventing, ameliorating or treating diseases related to the cartilage such as cartilage damages and cartilage disorders. Since the egg yolk protein hydrolyzate has an effect on chondrocyte proliferation promotion, it is useful as an active ingredient for preventing, ameliorating or treating cartilage disorders and for preventing, ameliorating or treating joint pain. The egg yolk protein hydrolyzate is a natural-origin material with high safety and, therefore, can be widely used in foods and drinks, medicines, feeds and the like which can be daily ingested.
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公开(公告)号：US20170332688A1
公开(公告)日：2017-11-23
申请号：US15522231
申请日：2015-10-30
发明人： Seiyu Harada , Toshio Nakamura , Mujo Kim
CPC分类号： A23L33/18 , A23L27/21 , A61K8/64 , A61K8/982 , A61K31/00 , A61K35/57 , A61K38/012 , A61K2800/92 , A61Q7/00
摘要： The present invention provides a hair regrowth promoter comprising an egg-yolk protein hydrolysate as an active ingredient. The egg-yolk protein hydrolysate is a safe ingredient produced from a natural source, and therefore can be widely used in daily consumable products, such as food and drink products, medicaments, animal feeds, and dietary supplements, or as a food additive, etc. The promoter etc. of the present invention can be orally administered and is thus very advantageous.
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