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公开(公告)号：US07980491B2
公开(公告)日：2011-07-19
申请号：US12036730
申请日：2008-02-25
CPC分类号： B05B1/3421 , A61M11/002 , A61M15/0021 , A61M15/009 , A61M2206/16 , B05B1/00 , B65D83/30
摘要： An improved atomization system for aerosolizing liquids including a vortexing nozzle and a flat or protruding face on the nozzle exit orifice. The system can also include a diverging mouthpiece insert. The present invention can produce a high fine particle fraction and modest throat deposition in conjunction with reduced aerosol plume velocity and impact force.
摘要翻译： 一种用于雾化液体的改进的雾化系统，包括涡流喷嘴和喷嘴出口上的平坦或突出的表面。 该系统还可以包括发散的接口插件。 本发明可以产生高细小颗粒分数和适度的咽喉沉积以及降低的气雾剂羽流速度和冲击力。
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公开(公告)号：US20080203193A1
公开(公告)日：2008-08-28
申请号：US12036730
申请日：2008-02-25
IPC分类号： B05B1/34
CPC分类号： B05B1/3421 , A61M11/002 , A61M15/0021 , A61M15/009 , A61M2206/16 , B05B1/00 , B65D83/30
摘要： An improved atomization system for aerosolizing liquids including a vortexing nozzle and a flat or protruding face on the nozzle exit orifice. The system can also include a diverging mouthpiece insert. The present invention can produce a high fine particle fraction and modest throat deposition in conjunction with reduced aerosol plume velocity and impact force.
摘要翻译： 一种用于雾化液体的改进的雾化系统，包括涡流喷嘴和喷嘴出口上的平坦或突出的表面。 该系统还可以包括发散的接口插件。 本发明可以产生高细小颗粒分数和适度的咽喉沉积以及降低的气雾剂羽流速度和冲击力。
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公开(公告)号：US20080178872A1
公开(公告)日：2008-07-31
申请号：US11947019
申请日：2007-11-29
IPC分类号： A61M15/00
CPC分类号： A61M15/0091 , A61M15/0026 , A61M15/0065 , A61M15/0066 , A61M15/008 , A61M15/009 , A61M15/0096 , A61M2205/3372 , A61M2205/502 , A61M2205/581 , A61M2205/582 , A61M2205/587 , A61M2205/8212
摘要： A dose selective breath actuated inhaler including a meterless canister storing a pressurized medicament, and a vacuum actuated release, where application of a vacuum to the inhaler initiates a release of the medicament in the canister. The inhaler includes a mechanism for dialing a proper dose of pressurized medicament, a computer for generating a plurality of signals including a solenoid trigger signal, and a solenoid which upon receipt of a solenoid trigger signal actuates a solenoid arm to end the release of the medicament from the canister.
摘要翻译： 剂量选择性呼吸致动吸入器，其包括存储加压药物的无量纲罐和真空致动释放器，其中向吸入器施加真空引发药剂在罐中的释放。 吸入器包括用于拨打适当剂量的加压药物的机构，用于产生包括螺线管触发信号的多个信号的计算机以及在接收到螺线管触发信号时致动电磁臂以终止药物释放的螺线管 从罐子。
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4.发明授权Method for cutting a suture to create tissue retainers of a desired shape and size 有权切割缝合线以形成所需形状和尺寸的组织保持器的方法公开(公告)号：US08015678B2
公开(公告)日：2011-09-13
申请号：US12850433
申请日：2010-08-04
IPC分类号： B21F25/00
CPC分类号： B26D3/08 , A61B17/06166 , A61B17/064 , A61B2017/00526 , A61B2017/06176 , Y10T29/20 , Y10T83/02 , Y10T83/0333 , Y10T83/0341 , Y10T83/0385 , Y10T83/04 , Y10T83/202 , Y10T83/4607 , Y10T83/896
摘要： A method for manufacturing self-retaining suture is disclosed. The method provides for creating and supporting a suture during cutting of tissue-grasping elements at different angular positions. A cutting device is moved through the suture thread along a path which can include longitudinal, transverse, oscillating and depth components to create a desired tissue-grasping element on the surface of the suture. The path of the cutting device and the rotation of the suture relative to the cutting device are controlled so that a plurality of angularly-displaced tissue-grasping elements can be created on the suture.
摘要翻译： 公开了一种用于制造自固位缝合线的方法。 该方法提供在切割不同角位置处的组织抓取元件时产生和支撑缝合线。 切割装置沿着可以包括纵向，横向，摆动和深度部件的路径移动穿过缝合线，以在缝合线的表面上产生期望的组织抓握元件。 控制切割装置的路径和缝合线相对于切割装置的旋转，使得可以在缝合线上形成多个角位移的组织抓握元件。
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公开(公告)号：US07624487B2
公开(公告)日：2009-12-01
申请号：US10437144
申请日：2003-05-13
CPC分类号： B26D1/0006 , A61B17/06166 , A61B2017/00526 , A61B2017/06176 , B26D7/01 , B26D2001/006 , Y10T29/20 , Y10T83/929 , Y10T428/29
摘要： An apparatus for cutting barbs into a suture having a filament supply. The apparatus also has an in-feed collet for holding one end of a filament threaded therethrough. Further the apparatus has an out-feed collet for holding a second end of a filament threaded therethrough. Additionally, the apparatus has a holder positioned between said in-feed and out-feed collets for holding a filament suspended between the in-feed and out-feed collets. The apparatus also has a cutting assembly for cutting barbs in the filament tensioned between the in-feed and out-feed collets.
摘要翻译： 一种用于将倒钩切割成具有丝线供应的缝合线的装置。 该装置还具有用于保持丝杠穿过的长丝的一端的进给夹头。 此外，该装置具有用于保持穿过其中的细丝的第二端的出料夹头。 另外，该装置具有定位在所述进料和出料夹头之间的保持器，用于保持悬挂在进料和出料夹头之间的细丝。 该设备还具有切割组件，用于切割在进给和出料夹头之间张紧的细丝中的倒钩。
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公开(公告)号：US08020263B2
公开(公告)日：2011-09-20
申请号：US12850498
申请日：2010-08-04
IPC分类号： B21F25/00
CPC分类号： B26D3/08 , A61B17/06166 , A61B17/064 , A61B2017/00526 , A61B2017/06176 , Y10T29/20 , Y10T83/02 , Y10T83/0333 , Y10T83/0341 , Y10T83/0385 , Y10T83/04 , Y10T83/202 , Y10T83/4607 , Y10T83/896
摘要： An automated system for manufacturing self-retaining suture is disclosed. The system includes a cutting bed to which a suture is mounted. A power-operated cutting arm moves a cutting device through the suture along a preselected path and at a preselected angle to create a tissue retainer having a desired geometry. An indexing mechanism moves the suture relative to the cutting device. The operation of the cutting arm in conjunction with the geometry of the cutting device and movement of the suture thread allows for creating a plurality of tissue retainers having a desired geometry distributed along the length of the suture thread.
摘要翻译： 公开了一种用于制造自固定缝线的自动化系统。 该系统包括切割床，缝合线被安装在该切割床上。 动力操作的切割臂沿着预选路径并且以预选的角度移动切割装置穿过缝合线，以产生具有期望几何形状的组织保持器。 分度机构相对于切割装置移动缝合线。 切割臂的操作结合切割装置的几何形状和缝合线的运动允许创建具有沿着缝合线的长度分布的期望几何形状的多个组织保持器。
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7.发明授权System for variable-angle cutting of a suture to create tissue retainers of a desired shape and size 有权用于可变角度切割缝合线以产生所需形状和尺寸的组织保持器的系统公开(公告)号：US07996967B2
公开(公告)日：2011-08-16
申请号：US12850397
申请日：2010-08-04
CPC分类号： B26D3/08 , A61B17/06166 , A61B17/064 , A61B2017/00526 , A61B2017/06176 , Y10T29/20 , Y10T83/02 , Y10T83/0333 , Y10T83/0341 , Y10T83/0385 , Y10T83/04 , Y10T83/202 , Y10T83/4607 , Y10T83/896
摘要： A system for manufacturing a self-retaining suture is disclosed. The system includes a cutting bed which supports the suture during cutting. A cutting device makes cuts in the suture thread having a preselected geometry. A cutting arm is articulated to allow change of the angle of the cutting device during cutting. The change in the angle of the cutting device is used to control the depth of cut and/or elevate a tissue-retainer away from the suture to better engage tissue.
摘要翻译： 公开了一种用于制造自固定缝合线的系统。 该系统包括在切割期间支撑缝合线的切割床。 切割装置使缝合线中的切口具有预选的几何形状。 切割臂被铰接以允许在切割期间改变切割装置的角度。 切割装置的角度变化用于控制切割深度和/或使组织保持器远离缝合线，以更好地接合组织。
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8.发明申请SYSTEM FOR CUTTING A SUTURE TO CREATE TISSUE RETAINERS OF A DESIRED SHAPE AND SIZE 有权用于切割产生所需形状和尺寸的组织保持器的系统公开(公告)号：US20100313723A1
公开(公告)日：2010-12-16
申请号：US12850480
申请日：2010-08-04
IPC分类号： B26D7/01
CPC分类号： B26D3/08 , A61B17/06166 , A61B17/064 , A61B2017/00526 , A61B2017/06176 , Y10T29/20 , Y10T83/02 , Y10T83/0333 , Y10T83/0341 , Y10T83/0385 , Y10T83/04 , Y10T83/202 , Y10T83/4607 , Y10T83/896
摘要： A system for manufacturing self-retaining suture is disclosed. The system includes a cutting bed for creating and supporting a suture during cutting of tissue-grasping elements at different angular positions. A cutting device is moved through the suture thread along a path which can include longitudinal, transverse, oscillating and depth components to create a desired tissue-grasping element on the surface of the suture. The path of the cutting device and the rotation of the suture relative to the cutting device are controlled so that a plurality of angularly-displaced tissue-grasping elements can be created on the suture.
摘要翻译： 公开了一种用于制造自固定缝线的系统。 该系统包括切割床，用于在不同角度位置切割组织抓握元件期间产生和支撑缝合线。 切割装置沿着可以包括纵向，横向，摆动和深度部件的路径移动穿过缝合线，以在缝合线的表面上产生期望的组织抓握元件。 控制切割装置的路径和缝合线相对于切割装置的旋转，使得可以在缝合线上形成多个角位移的组织抓握元件。
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公开(公告)号：US20100294104A1
公开(公告)日：2010-11-25
申请号：US12850447
申请日：2010-08-04
IPC分类号： B26D3/08
CPC分类号： B26D3/08 , A61B17/06166 , A61B17/064 , A61B2017/00526 , A61B2017/06176 , Y10T29/20 , Y10T83/02 , Y10T83/0333 , Y10T83/0341 , Y10T83/0385 , Y10T83/04 , Y10T83/202 , Y10T83/4607 , Y10T83/896
摘要： An automated method for manufacturing self-retaining suture is disclosed. The suture is mounted to a support. A power-operated cutting arm moves a cutting device through the suture along a preselected path and at a preselected angle to create a tissue retainer having a desired shape and size. The suture is indexed relative to the cutting device. The operation of the cutting arm in conjunction with the geometry of the cutting device and linear advancement of the suture thread allows for creating a plurality of tissue-retainers having a desired geometry along the length of the suture thread.
摘要翻译： 公开了一种用于制造自固位缝线的自动化方法。 缝合线安装在支架上。 动力操作的切割臂沿着预选路径并且以预选的角度移动切割装置穿过缝合线，以产生具有期望的形状和尺寸的组织保持器。 缝合线相对于切割装置进行索引。 切割臂的操作结合切割装置的几何形状和缝合线的线性前进允许创建沿着缝合线的长度具有所需几何形状的多个组织保持器。
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公开(公告)号：US08926659B2
公开(公告)日：2015-01-06
申请号：US12972802
申请日：2010-12-20
IPC分类号： A61B17/04 , B26D3/08 , A61B17/06 , A61B17/064 , A61B17/00
CPC分类号： B26D3/08 , A61B17/06166 , A61B17/064 , A61B2017/00526 , A61B2017/06176 , Y10T29/20 , Y10T83/02 , Y10T83/0333 , Y10T83/0341 , Y10T83/0385 , Y10T83/04 , Y10T83/202 , Y10T83/4607 , Y10T83/896
摘要： A barbed suture is disclosed having barbs defined by a variable-angle cut surface. A cutting bed supports the suture during cutting. A cutting device is moved through the suture thread along a selected path. The angle of the cutting device is changed during cutting so that there is a corresponding change in the angle of the cut surface which defines each barb. A cutting arm is articulated to allow change of the angle of the cutting device. The change in the angle of the cutting device is used to control the shape and depth of cut of the barbs.
摘要翻译： 公开了一种有倒钩的缝合线，其具有由可变角度切割表面限定的倒钩。 切割床在切割过程中支撑缝合线。 切割装置沿选定的路径移动穿过缝合线。 在切割期间切割装置的角度发生变化，从而限定每个倒钩的切割面的角度相应变化。 切割臂被铰接以允许切割装置的角度改变。 切割装置的角度变化用于控制倒钩的形状和深度。
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