Protein kinases
    9.
    发明申请
    Protein kinases 审中-公开
    蛋白激酶

    公开(公告)号:US20060121475A1

    公开(公告)日:2006-06-08

    申请号:US10526722

    申请日:2003-09-05

    摘要: The present invention relates to novel proteins, termed INSP081, INSP082, and INSP091, herein identified as members of the Germinal Center Kinase (GCK) subfamily of the STE20 family of protein kinases, preferably as NCK-interacting kinases (NIKs) and more preferably as NIK-like embryo specific kinases (NESKs), and to the use of these and nucleic acid sequences from the encoding genes in the diagnosis, prevention, and treatment of disease.

    摘要翻译: 本发明涉及称为INSP081,INSP082和INSP091的新蛋白质,其在本文中被鉴定为STE20家族蛋白激酶的生发中心激酶(GCK)亚家族的成员,优选作为NCK相互作用的激酶(NIK),更优选为 NIK样胚胎特异性激酶(NESKs),以及来自编码基因的这些和核酸序列在疾病的诊断,预防和治疗中的应用。