公开(公告)号：US20100179445A1

公开(公告)日：2010-07-15

申请号：US12687963

申请日：2010-01-15

申请人： Richard J. O'Brien ,  D. Curtis Deno ,  David A. Anderson ,  David R. Bloem

发明人： Richard J. O'Brien ,  D. Curtis Deno ,  David A. Anderson ,  David R. Bloem

IPC分类号： A61B5/0402 ,  G08B23/00

CPC分类号： A61B5/0002 ,  A61B5/0006 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/7207

摘要： A medical device includes one or more sensors used to acquire a multi-dimensional signal. In one embodiment, principal component analysis is performed on the multi-dimensional signal to produce signal data. The principal component analysis results are used to cancel signal artifact in one embodiment. A medical device controller produces one of a therapy control and a diagnostic output in response to the signal data.

公开(公告)号：US08391944B2

公开(公告)日：2013-03-05

申请号：US12687954

申请日：2010-01-15

申请人： Richard J. O'Brien ,  D. Curtis Deno ,  David A. Anderson ,  David R. Bloem

发明人： Richard J. O'Brien ,  D. Curtis Deno ,  David A. Anderson ,  David R. Bloem

IPC分类号： A61B5/1455 ,  A61N1/365

CPC分类号： A61N1/36514 ,  A61B5/0084 ,  A61B5/0086 ,  A61B5/02028 ,  A61B5/0464 ,  A61B5/7207

摘要： A medical device includes one or more sensors used to acquire a multi-dimensional signal. In one embodiment, principal component analysis is performed on the multi-dimensional signal to produce signal data. The principal component analysis results are used to cancel signal artifact in one embodiment. A medical device controller produces one of a therapy control and a diagnostic output in response to the signal data.

摘要翻译： 医疗装置包括用于获取多维信号的一个或多个传感器。 在一个实施例中，对多维信号执行主成分分析以产生信号数据。 在一个实施例中，主成分分析结果用于消除信号伪像。 医疗设备控制器响应于信号数据产生治疗控制和诊断输出之一。

公开(公告)号：US20100179444A1

公开(公告)日：2010-07-15

申请号：US12687946

申请日：2010-01-15

申请人： Richard J. O'Brien ,  D. Curtis Deno ,  David A. Anderson ,  David R. Bloem

发明人： Richard J. O'Brien ,  D. Curtis Deno ,  David A. Anderson ,  David R. Bloem

IPC分类号： A61B5/0402 ,  G08B23/00

CPC分类号： A61B5/0205 ,  A61B5/1455 ,  A61B5/7207 ,  A61N1/3718 ,  A61N1/3925 ,  G06K9/00503 ,  G06K9/6247 ,  G06K2009/00939

摘要： A medical device having a sensor sensing an n-dimensional signal during a first known variable condition and during a second known variable condition different from the first known variable condition, a processor performing principal component analysis (PCA) on the sensed n-dimensional signal to generate a first template corresponding to a principal component of variation associated with the first known variable condition and a second template corresponding to a principal component of variation associated with the second known variable condition, a storage device storing the first template and the second template, and a controller detecting a patient condition in response to the stored templates.

摘要翻译： 一种医疗装置，其具有在第一已知可变条件期间和在与第一已知可变条件不同的第二已知可变条件期间感测n维信号的传感器，处理器对所感测的n维信号执行主分量分析（PCA） 生成对应于与第一已知可变条件相关联的变化的主成分的第一模板和对应于与第二已知可变条件相关联的变化的主成分的第二模板，存储第一模板和第二模板的存储装置，以及 响应于所存储的模板检测患者状况的控制器。

公开(公告)号：US08706202B2

公开(公告)日：2014-04-22

申请号：US12687946

申请日：2010-01-15

申请人： Richard J. O'Brien ,  D. Curtis Deno ,  David A. Anderson ,  David R. Bloem

发明人： Richard J. O'Brien ,  D. Curtis Deno ,  David A. Anderson ,  David R. Bloem

IPC分类号： A61B5/04

CPC分类号： A61B5/0205 ,  A61B5/1455 ,  A61B5/7207 ,  A61N1/3718 ,  A61N1/3925 ,  G06K9/00503 ,  G06K9/6247 ,  G06K2009/00939

摘要： A medical device having a sensor sensing an n-dimensional signal during a first known variable condition and during a second known variable condition different from the first known variable condition, a processor performing principal component analysis (PCA) on the sensed n-dimensional signal to generate a first template corresponding to a principal component of variation associated with the first known variable condition and a second template corresponding to a principal component of variation associated with the second known variable condition, a storage device storing the first template and the second template, and a controller detecting a patient condition in response to the stored templates.

摘要翻译： 一种医疗装置，其具有在第一已知可变条件期间和在与第一已知可变条件不同的第二已知可变条件期间感测n维信号的传感器，处理器对所感测的n维信号执行主分量分析（PCA） 生成对应于与第一已知可变条件相关联的变化的主成分的第一模板和对应于与第二已知可变条件相关联的变化的主成分的第二模板，存储第一模板和第二模板的存储装置，以及 响应于所存储的模板检测患者状况的控制器。

公开(公告)号：US20100179611A1

公开(公告)日：2010-07-15

申请号：US12687954

申请日：2010-01-15

申请人： Richard J. O'Brien ,  D. Curtis Deno ,  David A. Anderson ,  David R. Bloem

发明人： Richard J. O'Brien ,  D. Curtis Deno ,  David A. Anderson ,  David R. Bloem

IPC分类号： A61N1/00 ,  G08B23/00 ,  A61B5/00

CPC分类号： A61N1/36514 ,  A61B5/0084 ,  A61B5/0086 ,  A61B5/02028 ,  A61B5/0464 ,  A61B5/7207

摘要： A medical device includes one or more sensors used to acquire a multi-dimensional signal. In one embodiment, principal component analysis is performed on the multi-dimensional signal to produce signal data. The principal component analysis results are used to cancel signal artifact in one embodiment. A medical device controller produces one of a therapy control and a diagnostic output in response to the signal data.

摘要翻译： 医疗装置包括用于获取多维信号的一个或多个传感器。 在一个实施例中，对多维信号执行主分量分析以产生信号数据。 在一个实施例中，主成分分析结果用于消除信号伪像。 医疗设备控制器响应于信号数据产生治疗控制和诊断输出之一。

公开(公告)号：US10362959B2

公开(公告)日：2019-07-30

申请号：US12465337

申请日：2009-05-13

申请人： Robert D. Aiken ,  D. Curtis Deno ,  Glen H. Kastner ,  Stephan P. Miller

发明人： Robert D. Aiken ,  D. Curtis Deno ,  Glen H. Kastner ,  Stephan P. Miller

IPC分类号： A61B5/053 ,  A61B5/06 ,  A61B18/12 ,  A61B18/14 ,  A61B18/16

摘要： A method and system for assessing proximity between an electrode and tissue is provided. The system includes an electronic control unit (ECU). The ECU is configured to acquire values for first and second components of a complex impedance between the electrode and the tissue, and to calculate an electrical coupling index (ECI) responsive to the first and second values. The ECU is further configured to process the ECI to determine the proximity of the electrode to the tissue. The ECU may be configured to calculate an electrical coupling index rate (ECIR) based on the calculated ECI and information relating to the change in location of the electrode, and to assess proximity based on the ECIR. Alternatively, the ECU may be configured to assess the proximity using the calculated ECI, as opposed to the ECIR.

公开(公告)号：US09186081B2

公开(公告)日：2015-11-17

申请号：US13977147

申请日：2011-12-20

申请人： Valtino X. Afonso ,  Jiazheng Shi ,  Steven J. Kim ,  D. Curtis Deno ,  Dennis J. Morgan

发明人： Valtino X. Afonso ,  Jiazheng Shi ,  Steven J. Kim ,  D. Curtis Deno ,  Dennis J. Morgan

IPC分类号： A61B5/042 ,  A61B5/044 ,  A61B5/06 ,  A61B5/00 ,  A61B5/053 ,  A61B18/14 ,  A61B19/00 ,  A61B18/00

CPC分类号： A61B5/0422 ,  A61B5/0044 ,  A61B5/04017 ,  A61B5/044 ,  A61B5/0452 ,  A61B5/0538 ,  A61B5/065 ,  A61B5/066 ,  A61B5/068 ,  A61B5/4836 ,  A61B5/6852 ,  A61B5/6855 ,  A61B18/1492 ,  A61B34/20 ,  A61B34/25 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2562/043 ,  A61B2576/023

摘要： An efficient system for diagnosing arrhythmias and directing catheter therapies may allow for measuring, classifying, analyzing, and mapping spatial electrophysiological (EP) patterns within a body. The efficient system may further guide arrhythmia therapy and update maps as treatment is delivered. The efficient system may use a medical device having a high density of sensors with a known spatial configuration for collecting EP data and positioning data. Further, the efficient system may also use an electronic control system (ECU) for computing and providing the user with a variety of metrics, derivative metrics, high definition (HD) maps, HD composite maps, and general visual aids for association with a geometrical anatomical model shown on a display device.

摘要翻译： 用于诊断心律失常和引导导管治疗的有效系统可以允许测量，分类，分析和映射身体内的空间电生理（EP）模式。 有效的系统可以进一步指导心律失常治疗并且随着治疗的进行更新地图。 有效的系统可以使用具有已知空间配置的高密度传感器的医疗装置来收集EP数据和定位数据。 此外，有效系统还可以使用电子控制系统（ECU）来计算并向用户提供各种度量，导数度量，高清（HD）地图，高清复合地图和用于与几何学 解剖模型显示在显示设备上。

公开(公告)号：US08900150B2

公开(公告)日：2014-12-02

申请号：US12982968

申请日：2010-12-31

申请人： D. Curtis Deno ,  Anthony D. Hill ,  Hua Zhong

发明人： D. Curtis Deno ,  Anthony D. Hill ,  Hua Zhong

IPC分类号： A61B8/12 ,  A61B5/06 ,  A61B18/14 ,  A61B18/00 ,  A61B19/00 ,  A61B5/00

CPC分类号： A61B8/0883 ,  A61B5/0422 ,  A61B5/06 ,  A61B5/061 ,  A61B5/063 ,  A61B5/7217 ,  A61B8/12 ,  A61B8/463 ,  A61B8/5238 ,  A61B18/14 ,  A61B34/20 ,  A61B2018/00755 ,  A61B2018/00839 ,  A61B2018/00875 ,  A61B2034/2051 ,  A61B2034/2053 ,  A61B2562/0209 ,  A61B2562/046 ,  Y10S128/916

摘要： A three dimensional physiological mapping system utilizing an intracardiac echo catheter capable of being located in six degrees of freedom by a visualization, navigation, or mapping system. An echocardiography image of the intracardiac echo catheter may be projected within a geometric model of the visualization, navigation, or mapping system where the location of the projected image is adjusted in response to user input identifying a structure present in the echocardiography image and the geometric model.

摘要翻译： 利用心内回波导管的三维生理测绘系统能够通过可视化，导航或绘图系统位于六自由度。 心内回波导管的超声心动图可以投射在可视化，导航或映射系统的几何模型内，其中根据用户输入来调整投影图像的位置，该用户输入识别存在于超声心动图图像和几何模型中的结构 。

公开(公告)号：US20120172724A1

公开(公告)日：2012-07-05

申请号：US12983013

申请日：2010-12-31

申请人： Anthony D. Hill ,  D. Curtis Deno ,  Hua Zhong ,  Martin M. Grasse

发明人： Anthony D. Hill ,  D. Curtis Deno ,  Hua Zhong ,  Martin M. Grasse

IPC分类号： A61B8/14

CPC分类号： A61B8/12 ,  A61B8/0841 ,  A61B8/0883 ,  A61B8/4245 ,  A61B8/461 ,  A61B8/463 ,  A61B8/5246 ,  G06T19/00 ,  G06T2210/41

摘要： An intracardiac imaging system configured to display electrode visualization elements within an intracardiac echocardiography image where the electrode visualization elements represent intracardiac electrodes in close proximity to the plane of the image. The system further allows cross sections of tissue structures embodied in intracardiac echocardiography images to be modeled within a visualization, navigation, or mapping system when automatically segmented to generate shell elements for modifying the modeled tissue structures.

摘要翻译： 心室内成像系统被配置为在心内超声心动图图像中显示电极可视化元件，其中电极可视化元件代表紧邻图像平面的心脏内电极。 当自动分段以产生用于修改建模的组织结构的壳单元时，系统进一步允许体现在心内超声心动图图像中的组织结构的横截面被建模在可视化，导航或映射系统内。

公开(公告)号：US20100168560A1

公开(公告)日：2010-07-01

申请号：US12347271

申请日：2008-12-31

申请人： John A. Hauck ,  Lubomir V. Dragnev ,  D. Curtis Deno ,  Eric J. Wilkowske

发明人： John A. Hauck ,  Lubomir V. Dragnev ,  D. Curtis Deno ,  Eric J. Wilkowske

IPC分类号： A61B5/05

CPC分类号： A61B5/068 ,  A61B5/06 ,  A61B5/062 ,  A61B5/6869 ,  A61B8/12 ,  A61B34/20 ,  A61B2017/003 ,  A61B2017/00336 ,  A61B2034/2051 ,  A61B2034/2053 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B2562/046 ,  A61M25/00 ,  A61M25/0105 ,  A61M25/0133

摘要： A medical device can be localized by providing at least three non-colinear localization elements (e.g., electrodes) thereon. Once placed in a non-ionizing localization field, three adjacent localization elements, at least one of which will typically be a spot electrode, may be selected, and the non-ionizing localization field may be used to measure their locations. A cylinder is defined to fit the measured locations of the selected localization elements. The cylinder is rotationally oriented using the measured location of a spot electrode. Location and rotational attitude information may be used to construct a three-dimensional representation of the medical device within the localization field. The electrodes may be provided on the medical device or on a sheath into which the medical device is inserted. The invention also provides systems and methods for identifying and calibrating deflection planes where the medical device and/or sheath are deflectable.

摘要翻译： 可通过在其上提供至少三个非共线定位元件（例如电极）来定位医疗装置。 一旦放置在非电离定位场中，可以选择三个相邻的定位元件，其中至少一个定位元件通常是点电极，并且非电离定位域可用于测量它们的位置。 气缸被定义为适合所选定位元件的测量位置。 圆柱体使用点电极的测量位置进行旋转定向。 位置和旋转姿态信息可以用于构建定位领域内的医疗装置的三维表示。 电极可以设置在医疗装置上或医疗装置插入的护套中。 本发明还提供用于识别和校准偏转平面的系统和方法，其中医疗装置和/或护套是可偏转的。