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公开(公告)号:US08311635B2
公开(公告)日:2012-11-13
申请号:US12487498
申请日:2009-06-18
IPC分类号: A61F9/08
CPC分类号: A61F9/08 , A61N1/36036 , A61N1/36046 , A61N1/36185
摘要: The present invention is a system for mapping a high resolution image to a lower resolution electrode array and, by applying varying stimulus to neighboring electrodes, creating a perceived image greater in resolution than the electrode array. The invention is applicable to a wide range of neural stimulation devices including artificial vision and artificial hearing. By applying a sub-threshold stimulus to two neighboring electrodes where the sum of the stimuli is above the threshold of perception, a perception is created in neural tissue between the two electrodes. By adjusting the stimulus on neighboring electrodes, the location of stimulation can be altered. Further, noise can be applied to the stimulating electrode or its neighboring electrodes to reduce the threshold of stimulation.
摘要翻译: 本发明是一种用于将高分辨率图像映射到较低分辨率电极阵列的系统,并且通过对相邻电极施加变化的刺激,产生比电极阵列更大的分辨率的感知图像。 本发明适用于包括人造视觉和人造听觉在内的各种神经刺激装置。 通过对刺激总和高于感知阈值的两个相邻电极施加亚阈值刺激,在两个电极之间的神经组织中产生感知。 通过调整相邻电极的刺激,可以改变刺激的位置。 此外,可以将刺激电极或其相邻电极施加噪声以降低刺激阈值。
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公开(公告)号:US07962221B2
公开(公告)日:2011-06-14
申请号:US11493471
申请日:2006-07-25
IPC分类号: A61N1/36
CPC分类号: A61N1/36046
摘要: A method and apparatus for adjusting a visual image provided to a patient. In one embodiment, an image may be presented to the patient to obtain the patient's subjective perception of the image, and the patient may either manipulate the image to obtain a desired adjustment, or guide a clinician performing the adjustment. In another embodiment, the clinician may make objective observations of, for example, the position of an electrode array on the patient's retina, and make adjustments accordingly. The adjustment may be a spatial adjustment comprising a re-mapping performed to decreases image distortion resulting from differences in the patient's perception of stimulation of different areas of the retina. Such distortion may result from differences between the patient's perception of stimulation falling within the macula, and stimulation falling within the periphery surrounding the macula. The adjustment may also compensate for translations or rotations of the electrode array on the retina.
摘要翻译: 一种用于调整提供给患者的视觉图像的方法和装置。 在一个实施例中,可以向患者呈现图像以获得患者对图像的主观感知,并且患者可以操纵图像以获得期望的调整,或指导进行调整的临床医师。 在另一个实施例中,临床医生可以对例如患者视网膜上的电极阵列的位置进行客观观察,并进行相应的调整。 调整可以是空间调整,其包括执行的重新映射,以减少由于患者对视网膜的不同区域的刺激的感知的差异而导致的图像失真。 这种变形可能由患者对黄斑内的刺激感知以及落在黄斑周围周边的刺激之间的差异引起。 该调整还可以补偿视网膜上的电极阵列的平移或旋转。
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公开(公告)号:US20090259276A1
公开(公告)日:2009-10-15
申请号:US12487498
申请日:2009-06-18
CPC分类号: A61F9/08 , A61N1/36036 , A61N1/36046 , A61N1/36185
摘要: The present invention is a system for mapping a high resolution image to a lower resolution electrode array and, by applying varying stimulus to neighboring electrodes, creating a perceived image greater in resolution than the electrode array. The invention is applicable to a wide range of neural stimulation devices including artificial vision and artificial hearing. By applying a sub-threshold stimulus to two neighboring electrodes where the sum of the stimuli is above the threshold of perception, a perception is created in neural tissue between the two electrodes. By adjusting the stimulus on neighboring electrodes, the location of stimulation can be altered. Further, noise can be applied to the stimulating electrode or its neighboring electrodes to reduce the threshold of stimulation.
摘要翻译: 本发明是一种用于将高分辨率图像映射到较低分辨率电极阵列的系统,并且通过对相邻电极施加变化的刺激,产生比电极阵列更大的分辨率的感知图像。 本发明适用于包括人造视觉和人造听觉在内的各种神经刺激装置。 通过对刺激总和高于感知阈值的两个相邻电极施加亚阈值刺激,在两个电极之间的神经组织中产生感知。 通过调整相邻电极的刺激,可以改变刺激的位置。 此外,可以将刺激电极或其相邻电极施加噪声以降低刺激阈值。
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公开(公告)号:US08014869B2
公开(公告)日:2011-09-06
申请号:US11493474
申请日:2006-07-25
IPC分类号: A61N1/36
CPC分类号: A61N1/36046
摘要: A method and apparatus for adjusting a visual image provided to a patient. In one embodiment, an image may be presented to the patient to obtain the patient's subjective perception of the image, and the patient may either manipulate the image to obtain a desired adjustment, or guide a clinician performing the adjustment. In another embodiment, the clinician may make objective observations of, for example, the position of an electrode array on the patient's retina, and make adjustments accordingly. The adjustment may be a spatial adjustment comprising a re-mapping performed to decreases image distortion resulting from differences in the patient's perception of stimulation of different areas of the retina. Such distortion may result from differences between the patient's perception of stimulation falling within the macula, and stimulation falling within the periphery surrounding the macula. The adjustment may also compensate for translations or rotations of the electrode array on the retina.
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公开(公告)号:US07574263B2
公开(公告)日:2009-08-11
申请号:US10355791
申请日:2003-01-31
IPC分类号: A61N1/36
CPC分类号: A61N1/36046
摘要: A method and apparatus for adjusting a visual image provided to a patient. In one embodiment, an image may be presented to the patient to obtain the patient's subjective perception of the image, and the patient may either manipulate the image to obtain a desired adjustment, or guide a clinician performing the adjustment. In another embodiment, the clinician may make objective observations of, for example, the position of an electrode array on the patient's retina, and make adjustments accordingly. The adjustment may be a spatial adjustment comprising a re-mapping performed to decreases image distortion resulting from differences in the patient's perception of stimulation of different areas of the retina. Such distortion may result from differences between the patient's perception of stimulation falling within the macula, and stimulation falling within the periphery surrounding the macula. The adjustment may also compensate for translations or rotations of the electrode array on the retina.
摘要翻译: 一种用于调整提供给患者的视觉图像的方法和装置。 在一个实施例中,可以向患者呈现图像以获得患者对图像的主观感知,并且患者可以操纵图像以获得期望的调整,或指导进行调整的临床医师。 在另一个实施例中,临床医生可以对例如患者视网膜上的电极阵列的位置进行客观观察,并进行相应的调整。 调整可以是空间调整,其包括执行的重新映射,以减少由于患者对视网膜的不同区域的刺激的感知的差异而导致的图像失真。 这种变形可能由患者对黄斑内的刺激感知以及落在黄斑周围周边的刺激之间的差异引起。 该调整还可以补偿视网膜上的电极阵列的平移或旋转。
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公开(公告)号:US07565202B2
公开(公告)日:2009-07-21
申请号:US10355793
申请日:2003-01-31
IPC分类号: A61N1/18
CPC分类号: A61N1/0543 , A61N1/36036 , A61N1/36046
摘要: The present invention is a system for mapping a high resolution image to a lower resolution electrode array and, by applying varying stimulus to neighboring electrodes, creating a perceived image greater in resolution than the electrode array. The invention is applicable to a wide range of neural stimulation devices including artificial vision and artificial hearing. By applying a sub-threshold stimulus to two neighboring electrodes where the sum of the stimuli is above the threshold of perception, a perception is created in neural tissue between the two electrodes. By adjusting the stimulus on neighboring electrodes, the location of stimulation can be altered. Further, noise can be applied to the stimulating electrode or its neighboring electrodes to reduce the threshold of stimulation.
摘要翻译: 本发明是一种用于将高分辨率图像映射到较低分辨率电极阵列的系统,并且通过对相邻电极施加变化的刺激,产生比电极阵列更大的分辨率的感知图像。 本发明适用于包括人造视觉和人造听觉在内的各种神经刺激装置。 通过对刺激总和高于感知阈值的两个相邻电极施加亚阈值刺激,在两个电极之间的神经组织中产生感知。 通过调整相邻电极的刺激,可以改变刺激的位置。 此外,可以将刺激电极或其相邻电极施加噪声以降低刺激阈值。
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公开(公告)号:US10065036B2
公开(公告)日:2018-09-04
申请号:US11906167
申请日:2007-09-28
摘要: The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.
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公开(公告)号:US09943688B2
公开(公告)日:2018-04-17
申请号:US13163506
申请日:2011-06-17
CPC分类号: A61N1/36046 , A61N1/086 , G01R33/4806
摘要: The present invention is wireless visual prosthesis with a remote driver for the external coils this, among other things, provides for a magnetic resonance image (MRI) safe visual prosthesis. fMRI is an effective tool for analyzing cortical responses to neural stimulation, such as from a visual prosthesis. However, the external electronics of a visual prosthesis cannot operate in a MRI field. The present invention provides a radio frequency shielded link between a video processing unit, driver circuitry and the coils used for communicating with the implantable portion of the visual prosthesis.
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9.
公开(公告)号:US09643002B2
公开(公告)日:2017-05-09
申请号:US13167074
申请日:2011-06-23
申请人: Robert J. Greenberg , Neil Hamilton Talbot , Jordan Matthew Neysmith , James Singleton Little , Brian V. Mech
发明人: Robert J. Greenberg , Neil Hamilton Talbot , Jordan Matthew Neysmith , James Singleton Little , Brian V. Mech
CPC分类号: A61N1/0543 , A61N1/36046 , H05K1/036 , H05K1/0393 , H05K1/118 , H05K3/0014 , H05K2201/05 , H05K2201/053 , H05K2201/09063 , H05K2201/09409 , Y10T29/49002 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156 , Y10T29/49158 , Y10T29/49174 , Y10T29/49176
摘要: The present invention provides a flexible circuit electrode array adapted for neural stimulation, comprising: a polymer base layer; metal traces deposited on the polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on the polymer base layer and the metal traces at least one tack opening. The present invention provides further a method of making a flexible circuit electrode array comprising depositing a polymer base layer; depositing metal on the polymer base layer; patterning the metal to form metal traces; depositing a polymer top layer on the polymer base layer and the metal traces; and preparing at least one tack opening.
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公开(公告)号:US09592377B2
公开(公告)日:2017-03-14
申请号:US12180436
申请日:2008-07-25
CPC分类号: A61N1/0531 , A61N1/0534 , A61N1/0539 , A61N1/36082 , A61N1/37229 , A61N1/375 , A61N1/3758 , A61N1/3787 , H05K1/028 , H05K1/111 , H05K1/141 , H05K1/147 , H05K3/284
摘要: The present invention consists of an implantable device with at least one package that houses electronics that receives input data or signals, and optionally power, from an external system through at least one coil attached to the at least one package, processes the input data and delivers electrical pulses to neural tissue through at least one array of multiple electrodes that is/are attached to the at least one package. The invention, or components thereof, is/are intended to be installed in the head, or on or in the cranium or on the dura, or on or in the brain.
摘要翻译: 本发明包括具有至少一个封装的可植入装置,所述至少一个封装容纳电子装置,所述电子装置通过连接到所述至少一个封装件的至少一个线圈从外部系统接收输入数据或信号以及可选地供电,处理所述输入数据并传送 通过至少一个连接到至少一个封装的多个电极阵列的电脉冲到神经组织。 本发明或其组分旨在安装在头部,或在头颅或硬脑膜上,或脑中或脑中。
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