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公开(公告)号：US20100266794A1
公开(公告)日：2010-10-21
申请号：US12747558
申请日：2008-12-12
申请人： Robin E. Wright , Stephen E. Krampe , Richard L. Walter , Caroline M. Ylitalo , William A. Eibner , Jeffrey H. Tokie , Matthew T. Scholz
发明人： Robin E. Wright , Stephen E. Krampe , Richard L. Walter , Caroline M. Ylitalo , William A. Eibner , Jeffrey H. Tokie , Matthew T. Scholz
CPC分类号： B32B37/24 , A61L15/60 , B05D1/02 , B05D3/06 , B32B38/0008 , B32B2038/0076 , B32B2305/74 , B32B2307/728 , B32B2386/00 , C08F2/48 , C08F290/06 , C08F290/061 , C08F290/062 , C08F299/00 , C09J133/14 , Y10T428/1352
摘要： The present disclosure describes articles, such as medical articles, containing a substrate having disposed thereon a hydrophilic gel material (e.g., a shaped hydrophilic gel material or a coating of a hydrophilic gel material) and methods for making such articles. Methods are provided for making hydrophilic gel materials from a precursor composition that contains a polar solvent and a polymerizable material that is miscible with the polar solvent.
摘要翻译： 本公开描述了包含其上设置有亲水性凝胶材料（例如，成形亲水凝胶材料或亲水性凝胶材料的涂层）的基底的制品，例如医疗制品以及制造这种制品的方法。 提供了从含有极性溶剂和可与极性溶剂混溶的可聚合材料的前体组合物制备亲水凝胶材料的方法。
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公开(公告)号：US07939578B2
公开(公告)日：2011-05-10
申请号：US11847397
申请日：2007-08-30
申请人： Robin E. Wright , Mahfuza B. Ali , Jessica M. Buchholz , Louis C. Haddad , Linda K. M. Olson , Matthew T. Scholz , Narina Y. Stepanova , Michael J. Svarovsky , Richard L. Walter , Caroline M. Ylitalo , Diane R. Wolk , Yifan Zhang
发明人： Robin E. Wright , Mahfuza B. Ali , Jessica M. Buchholz , Louis C. Haddad , Linda K. M. Olson , Matthew T. Scholz , Narina Y. Stepanova , Michael J. Svarovsky , Richard L. Walter , Caroline M. Ylitalo , Diane R. Wolk , Yifan Zhang
CPC分类号： D01D5/00 , D01D5/38 , D01F1/103 , D01F6/16 , D01F6/28 , Y10T428/29 , Y10T428/2913 , Y10T428/2964 , Y10T428/2967 , Y10T428/2969
摘要： Polymeric fibers and methods of making the polymeric fibers are described. The polymeric fibers are crosslinked hydrogels or dried hydrogels that are prepared from a precursor composition that contains polymerizable material having an average number of ethylenically unsaturated groups per monomer molecule greater than 1.0. The polymeric fibers can contain an optional active agent.
摘要翻译： 描述了聚合纤维和制备聚合物纤维的方法。 聚合物纤维是交联的水凝胶或干燥的水凝胶，其由含有每单体分子的平均数量的烯属不饱和基团大于1.0的可聚合材料的前体组合物制备。 聚合物纤维可以含有任选的活性剂。
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公开(公告)号：US20080300339A1
公开(公告)日：2008-12-04
申请号：US11759283
申请日：2007-06-07
申请人： Robin E. Wright , Mahfuza B. Ali , Jessica M. Buchholz , Louis C. Haddad , Linda K.M. Olson , Matthew T. Scholz , Narina Y. Stepanova , Michael J. Svarovsky , Richard L. Walter , Caroline M. Ylitalo , Diane R. Wolk , Yifan Zhang
发明人： Robin E. Wright , Mahfuza B. Ali , Jessica M. Buchholz , Louis C. Haddad , Linda K.M. Olson , Matthew T. Scholz , Narina Y. Stepanova , Michael J. Svarovsky , Richard L. Walter , Caroline M. Ylitalo , Diane R. Wolk , Yifan Zhang
IPC分类号： C08J3/28
摘要： Polymeric beads and methods of making the polymeric beads are described. The polymeric beads are crosslinked hydrogels or dried hydrogels. The polymeric beads are formed from droplets of a precursor composition that are exposed to radiation. The droplets are totally surrounded by a gas phase. The precursor composition contains a polar solvent and a polymerizable material miscible in the polar solvent. The polymerizable material has an average number of ethylenically unsaturated groups per monomer molecule equal to at least 1.2.
摘要翻译： 描述了聚合珠和制备聚合物珠的方法。 聚合物珠是交联水凝胶或干水凝胶。 聚合物珠由暴露于辐射的前体组合物的液滴形成。 液滴完全被气相包围。 前体组合物含有极性溶剂和可在极性溶剂中混溶的可聚合材料。 可聚合材料具有等于至少1.2的每单体分子的烯属不饱和基团的平均数。
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公开(公告)号：US20080207794A1
公开(公告)日：2008-08-28
申请号：US11847397
申请日：2007-08-30
申请人： Robin E. Wright , Mahfuza B. Ali , Jessica M. Buchholz , Louis C. Haddad , Linda K.M. Olson , Matthew T. Scholz , Narina Y. Stepanova , Michael J. Svarovsky , Richard L. Walter , Caroline M. Ylitalo , Diane R. Wolk , Yifan Zhang
发明人： Robin E. Wright , Mahfuza B. Ali , Jessica M. Buchholz , Louis C. Haddad , Linda K.M. Olson , Matthew T. Scholz , Narina Y. Stepanova , Michael J. Svarovsky , Richard L. Walter , Caroline M. Ylitalo , Diane R. Wolk , Yifan Zhang
CPC分类号： D01D5/00 , D01D5/38 , D01F1/103 , D01F6/16 , D01F6/28 , Y10T428/29 , Y10T428/2913 , Y10T428/2964 , Y10T428/2967 , Y10T428/2969
摘要： Polymeric fibers and methods of making the polymeric fibers are described. The polymeric fibers are crosslinked hydrogels or dried hydrogels that are prepared from a precursor composition that contains polymerizable material having an average number of ethylenically unsaturated groups per monomer molecule greater than 1.0. The polymeric fibers can contain an optional active agent.
摘要翻译： 描述了聚合纤维和制备聚合物纤维的方法。 聚合物纤维是交联的水凝胶或干燥的水凝胶，其由含有每单体分子的平均数量的烯属不饱和基团大于1.0的可聚合材料的前体组合物制备。 聚合物纤维可以含有任选的活性剂。
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公开(公告)号：US08513322B2
公开(公告)日：2013-08-20
申请号：US11759283
申请日：2007-06-07
申请人： Robin E. Wright , Mahfuza B. Ali , Jessica M. Buchholz , Louis C. Haddad , Linda K. M. Olson , Matthew T. Scholz , Narina Y. Stepanova , Michael J. Svarovsky , Richard L. Walter , Caroline M. Ylitalo , Diane R. Wolk , Yifan Zhang
发明人： Robin E. Wright , Mahfuza B. Ali , Jessica M. Buchholz , Louis C. Haddad , Linda K. M. Olson , Matthew T. Scholz , Narina Y. Stepanova , Michael J. Svarovsky , Richard L. Walter , Caroline M. Ylitalo , Diane R. Wolk , Yifan Zhang
摘要： Polymeric beads and methods of making the polymeric beads are described. The polymeric beads are crosslinked hydrogels or dried hydrogels. The polymeric beads are formed from droplets of a precursor composition that are exposed to radiation. The droplets are totally surrounded by a gas phase. The precursor composition contains a polar solvent and a polymerizable material miscible in the polar solvent. The polymerizable material has an average number of ethylenically unsaturated groups per monomer molecule equal to at least 1.2.
摘要翻译： 描述了聚合珠和制备聚合物珠的方法。 聚合物珠是交联水凝胶或干水凝胶。 聚合物珠由暴露于辐射的前体组合物的液滴形成。 液滴完全被气相包围。 前体组合物含有极性溶剂和可在极性溶剂中混溶的可聚合材料。 可聚合材料具有等于至少1.2的每单体分子的烯属不饱和基团的平均数。
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公开(公告)号：US20100295219A1
公开(公告)日：2010-11-25
申请号：US12747182
申请日：2008-12-08
申请人： Caroline M. Ylitalo , Robin E. Wright , Matthew T. Scholz , Narina Y. Stepanova , Jessica M. Buchholz
发明人： Caroline M. Ylitalo , Robin E. Wright , Matthew T. Scholz , Narina Y. Stepanova , Jessica M. Buchholz
IPC分类号： B29C35/08
CPC分类号： C08F290/06 , A01N25/34 , B33Y80/00 , C08F2/48 , C08F290/061 , C08F290/062 , C08F299/00 , Y10T156/1168 , Y10T428/15 , Y10T428/16 , Y10T428/24 , Y10T428/24479 , Y10T428/2462
摘要： The present disclosure describes methods for making shaped polymeric materials. Methods are provided for making shaped polymeric materials from a precursor composition that contains a polar solvent and a polymerizable material that is miscible with the polar solvent. The precursor composition is at least partially polymerized in a mold.
摘要翻译： 本公开描述了制造成型聚合物材料的方法。 提供了从含有极性溶剂和可与极性溶剂混溶的可聚合材料的前体组合物制备成形聚合材料的方法。 前体组合物在模具中至少部分聚合。
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公开(公告)号：US08696975B2
公开(公告)日：2014-04-15
申请号：US12747182
申请日：2008-12-08
申请人： Caroline M. Ylitalo , Robin E. Wright , Matthew T. Scholz , Narina Y. Stepanova , Jessica M. Buchholz
发明人： Caroline M. Ylitalo , Robin E. Wright , Matthew T. Scholz , Narina Y. Stepanova , Jessica M. Buchholz
IPC分类号： B29C35/08 , C08F299/02
CPC分类号： C08F290/06 , A01N25/34 , B33Y80/00 , C08F2/48 , C08F290/061 , C08F290/062 , C08F299/00 , Y10T156/1168 , Y10T428/15 , Y10T428/16 , Y10T428/24 , Y10T428/24479 , Y10T428/2462
摘要： The present disclosure describes methods for making shaped polymeric materials. Methods are provided for making shaped polymeric materials from a precursor composition that contains a polar solvent and a polymerizable material that is miscible with the polar solvent. The precursor composition is at least partially polymerized in a mold.
摘要翻译： 本公开描述了制造成型聚合物材料的方法。 提供了从含有极性溶剂和可与极性溶剂混溶的可聚合材料的前体组合物制备成形聚合材料的方法。 前体组合物在模具中至少部分聚合。
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公开(公告)号：US09809717B2
公开(公告)日：2017-11-07
申请号：US13699345
申请日：2011-05-25
申请人： Mahfuza B. Ali , Naiyong Jing , Valeri Lirine , Pradnya V. Nagarkar , Caroline M. Ylitalo , Nancy S. Lennhoff , Matthew T. Scholz , Ranjani V. Parthasarathy
发明人： Mahfuza B. Ali , Naiyong Jing , Valeri Lirine , Pradnya V. Nagarkar , Caroline M. Ylitalo , Nancy S. Lennhoff , Matthew T. Scholz , Ranjani V. Parthasarathy
IPC分类号： A61L29/08 , C09D5/16 , C03C17/30 , C03C17/42 , C08F220/34 , C08G77/26 , C09D183/10 , G06F3/041 , A61L29/16 , B05D3/02 , B05D3/06 , G06F3/047 , C08F220/06 , C08F220/18 , C08F230/08
CPC分类号： C09D5/1637 , A61L29/085 , A61L29/16 , A61L2300/216 , A61L2300/404 , A61L2420/02 , B05D3/02 , B05D3/06 , C03C17/30 , C03C17/42 , C08F220/06 , C08F220/18 , C08F220/34 , C08F230/08 , C08G77/26 , C09D5/1675 , C09D5/1693 , C09D183/10 , G06F3/041 , G06F3/047 , Y10T428/31663
摘要： The disclosure provides polymers having antimicrobial activity and articles with the polymers coated thereon. The polymers include a first pendant group comprising a first cationic component, a second pendant group comprising a nonpolar component, and a third pendant group comprising an organosilane component. The disclosure also includes methods of coating medical device articles and body fluid-receiving substrates with the antimicrobial polymers. The methods further include the use of adhesion-promoting components.
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公开(公告)号：US09247736B2
公开(公告)日：2016-02-02
申请号：US12094758
申请日：2006-12-14
申请人： Caroline M. Ylitalo , Mahfuza B. Ali , Christopher B. Walker, Jr. , Gerald R. A. Hofmann , Matthew T. Scholz , Alphonsus V. Pocius , Linda K. M. Olson
发明人： Caroline M. Ylitalo , Mahfuza B. Ali , Christopher B. Walker, Jr. , Gerald R. A. Hofmann , Matthew T. Scholz , Alphonsus V. Pocius , Linda K. M. Olson
IPC分类号： A01N25/34 , A01N33/12 , B32B27/18 , C08J5/18 , B32B7/06 , B32B7/12 , B32B27/08 , B32B27/30 , B32B27/32 , B32B27/36 , C09J133/14 , A01N59/16 , C08F220/34
CPC分类号： A01N25/34 , A01N59/16 , B32B7/06 , B32B7/12 , B32B27/08 , B32B27/18 , B32B27/308 , B32B27/32 , B32B27/36 , B32B2264/10 , B32B2264/105 , B32B2307/412 , B32B2307/7145 , B32B2307/75 , B32B2405/00 , B32B2479/00 , C08F220/34 , C08J5/18 , C08J2357/00 , C09J133/14 , A01N59/20 , A01N33/12 , A01N31/16 , A01N37/06 , A01N37/02 , A01N37/10 , A01N37/40 , A01N47/44 , A01N65/00 , A01N55/04
摘要： A multi-layer film for reducing microbial contamination on a surface. The multi-layer film can include a core layer having a first surface and a second surface opposite the first surface, an adhesive layer disposed adjacent the first surface of the core layer, and an antimicrobial layer disposed adjacent the second surface. The antimicrobial layer can include a cross-linked matrix and an antimicrobial agent dispersed within the cross-linked matrix, where the cross-linked matrix is derived from a polymerizable precursor comprising a material selected from the group consisting of a polymerizable monomer, a polymerizable polymer having a molecular weight of about 1,000 or less, and combinations thereof.
摘要翻译： 用于减少表面微生物污染的多层薄膜。 多层膜可以包括具有第一表面和与第一表面相对的第二表面的芯层，邻近芯层的第一表面设置的粘合剂层和邻近第二表面设置的抗微生物层。 抗微生物层可以包括分散在交联基质内的交联基质和抗微生物剂，其中交联基质衍生自可聚合前体，其包含选自可聚合单体，可聚合聚合物 具有约1,000或更小的分子量，及其组合。
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公开(公告)号：US20090130157A1
公开(公告)日：2009-05-21
申请号：US12094758
申请日：2006-12-14
申请人： Caroline M. Ylitalo , Mahfuza B. Ali , Christopher B. Walker, JR. , Gerald R.A. Hofmann , Matthew T. Scholz , Alphonsus V. Pocius , Linda K.M. Olson
发明人： Caroline M. Ylitalo , Mahfuza B. Ali , Christopher B. Walker, JR. , Gerald R.A. Hofmann , Matthew T. Scholz , Alphonsus V. Pocius , Linda K.M. Olson
CPC分类号： A01N25/34 , A01N59/16 , B32B7/06 , B32B7/12 , B32B27/08 , B32B27/18 , B32B27/308 , B32B27/32 , B32B27/36 , B32B2264/10 , B32B2264/105 , B32B2307/412 , B32B2307/7145 , B32B2307/75 , B32B2405/00 , B32B2479/00 , C08F220/34 , C08J5/18 , C08J2357/00 , C09J133/14 , A01N59/20 , A01N33/12 , A01N31/16 , A01N37/06 , A01N37/02 , A01N37/10 , A01N37/40 , A01N47/44 , A01N65/00 , A01N55/04
摘要： A multi-layer film for reducing microbial contamination on a surface. The multi-layer film can include a core layer having a first surface and a second surface opposite the first surface, an adhesive layer disposed adjacent the first surface of the core layer, and an antimicrobial layer disposed adjacent the second surface. The antimicrobial layer can include a cross-linked matrix and an antimicrobial agent dispersed within the cross-linked matrix, where the cross-linked matrix is derived from a polymerizable precursor comprising a material selected from the group consisting of a polymerizable monomer, a polymerizable polymer having a molecular weight of about 1,000 or less, and combinations thereof.
摘要翻译： 用于减少表面微生物污染的多层薄膜。 多层膜可以包括具有第一表面和与第一表面相对的第二表面的芯层，邻近芯层的第一表面设置的粘合剂层和邻近第二表面设置的抗微生物层。 抗微生物层可以包括分散在交联基质内的交联基质和抗微生物剂，其中交联基质衍生自可聚合前体，其包含选自可聚合单体，可聚合聚合物 具有约1,000或更小的分子量，及其组合。
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