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    Hair cosmetic composition
    1.
    发明授权
    Hair cosmetic composition 失效
    头发化妆品组成

    公开(公告)号：US5587155A

    公开(公告)日：1996-12-24

    申请号：US367228

    申请日：1995-01-18

    申请人： Ryuji Ochiai ,  Kouzi Morita ,  Kazuyuki Yahagi

    发明人： Ryuji Ochiai ,  Kouzi Morita ,  Kazuyuki Yahagi

    IPC分类号： A61K8/00 ,  A61K8/34 ,  A61K8/36 ,  A61K8/37 ,  A61K8/39 ,  A61K8/41 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/06 ,  A61Q5/12 ,  A61K7/06 ,  A61K7/00

    CPC分类号： A61K8/39 ,  A61K8/34 ,  A61K8/342 ,  A61K8/345 ,  A61K8/361 ,  A61K8/416 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/06 ,  A61Q5/12

    摘要： A hair cosmetic composition including (a) at least one compound selected from fatty acids containing a linear or branched alkyl or alkenyl group having 12-40 carbon atoms, salts thereof and fatty acid esters composed of one of the fatty acids and a polyhydric alcohol; (b) at least one aromatic alcohol represented by the general formula (1): ##STR1## wherein R.sup.1 means a hydrogen atom or a methyl or methoxy group, Y denotes a single bond or a linear or branched alkylene or alkenylene group having 1-3 carbon atoms, Z is a hydrogen atom or a hydroxyl group, and p and q stand individually for a number of 0-5; and (c) at least one cationic surfactant. The hair cosmetic composition has neither sticky nor oily feel to the touch, is excellent in hair-conditioning effects of, for example, giving users a moistured feel of the hair and imparting softness and smoothness to the hair, gives resilience to the hair and is superb in effects of preventing damage to the hair and of keeping the waves or curls of the hair beautiful.

    摘要翻译： PCT No.PCT / JP93 / 00980 Sec。 371 1995年1月18日第 102（e）日期1995年1月18日PCT提交1993年7月14日PCT公布。 公开号WO94 / 02111 日本1994年2月3日一种美发组合物，其包含（a）至少一种选自含有12-40个碳原子的直链或支链烷基或烯基的脂肪酸的化合物，其盐和由脂肪酸之一组成的脂肪酸酯 和多元醇; （b）至少一种由通式（1）表示的芳族醇：甲基或甲氧基，Y表示单键或具有1-3个碳原子的直链或支链亚烷基或亚链烯基，Z表示氢原子或 羟基，p和q分别独立地为0-5个数; 和（c）至少一种阳离子表面活性剂。 头发美容组合物既没有粘性也没有油腻的感觉，例如赋予使用者头发的湿润感和赋予头发柔软和光滑的头发调理效果优异，赋予毛发弹性，并且 极好的防止头发损伤和保持头发美丽的波浪或卷曲的效果。

    Method of treating hypertension
    3.
    发明授权
    Method of treating hypertension 有权
    治疗高血压的方法

    公开(公告)号：US06310100B1

    公开(公告)日：2001-10-30

    申请号：US09667794

    申请日：2000-09-22

    申请人： Atsushi Suzuki ,  Ryuji Ochiai ,  Ichiro Tokimitsu

    发明人： Atsushi Suzuki ,  Ryuji Ochiai ,  Ichiro Tokimitsu

    IPC分类号： A61K3119

    CPC分类号： A61K9/0095 ,  A23L33/10 ,  A61K9/4858 ,  A61K31/192 ,  A61K45/06 ,  A61K2300/00

    摘要： A method for treating hypertension, a cardiac disease, or a cerebrovascular disease comprising administration of ferulic acid or a derivative thereof, to a subject in need of treatment. Therapeutic compositions comprising ferulic acid and its derivatives may comprise pharmaceutical products, nutritional supplements or products, and foods. Such compositions may further comprising diglycerides in combination with ferulic acid and its derivatives.

    摘要翻译： 一种治疗高血压，心脏病或脑血管疾病的方法，包括向需要治疗的受试者施用阿魏酸或其衍生物。 包含阿魏酸及其衍生物的治疗组合物可包含药物产品，营养补充剂或产品和食品。 这样的组合物还可以包含与阿魏酸及其衍生物组合的甘油二酯。

    LIQUID SEASONING
    5.
    发明申请
    LIQUID SEASONING 有权
    液体季节

    公开(公告)号：US20090098268A1

    公开(公告)日：2009-04-16

    申请号：US12093676

    申请日：2006-11-14

    申请人： Shin Koike ,  Koichi Okisaka ,  Jun Kohori ,  Yoko Seo ,  Noboru Shirahata ,  Hiroyuki Nakayama ,  Atsushi Suzuki ,  Ryuji Ochiai

    发明人： Shin Koike ,  Koichi Okisaka ,  Jun Kohori ,  Yoko Seo ,  Noboru Shirahata ,  Hiroyuki Nakayama ,  Atsushi Suzuki ,  Ryuji Ochiai

    IPC分类号： A23L1/22

    CPC分类号： A23L17/00 ,  A23L27/40 ,  A23L27/50 ,  A23L27/60 ,  A23L33/105

    摘要： The present invention is a liquid seasoning containing the following (A), (B), and (C): (A) 0.4 to 8% by mass of sodium (B) 0.01 to 4% by mass of flavonoid (C) 1 to 10% by mass of ethanol wherein, the flavonoid (B) satisfies the formula (1) and/or has one or more OH groups on the A-ring or B-ring in a molecule and no OH group at the position adjacent to the OH group (ortho position). Y/(X+Y)=0.05 to 1  formula (1) wherein, X and Y represent the following numbers, respectively: X; the number of OH group bonded to benzene rings in a molecule of the flavonoid, Y; the number of OCH3 group bonded to benzene rings in a molecule of the flavonoid.

    摘要翻译： 本发明是含有以下（A），（B）和（C）的液体调味料：（A）0.4〜8质量％的钠（B）0.01〜4质量％的类黄酮（C） 10质量％的乙醇，其中类黄酮（B）满足式（1）和/或在分子中在A环或B环上具有一个或多个OH基，并且在与 OH基（邻位）。 <？in-line-formula description =“In-line Formulas”end =“lead”？> Y /（X + Y）= 0.05〜1式（1）<？in-line-formula description =“In-line 公式“end =”tail“？>其中，X和Y分别表示以下数字：X; 在一类黄酮分子中与苯环键合的OH基数Y; 在类黄酮分子中与苯环键合的OCH 3基团的数目。

    Agent for preventing, improving or treating hypertension
    7.
    发明授权
    Agent for preventing, improving or treating hypertension 有权

    公开(公告)号：US06991812B2

    公开(公告)日：2006-01-31

    申请号：US09944079

    申请日：2001-09-04

    申请人： Atsushi Suzuki ,  Ryuji Ochiai ,  Ichiro Tokimitsu

    发明人： Atsushi Suzuki ,  Ryuji Ochiai ,  Ichiro Tokimitsu

    IPC分类号： A61K35/78

    CPC分类号： A61K31/19 ,  A61K31/192 ,  A61K36/67 ,  A61K36/81 ,  A61K36/82 ,  A61K36/906 ,  A61K2300/00

    摘要： The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension. The agent for preventing, improving or treating hypertension contains the following components (A) and (B): (A) a compound selected from the group consisting of caffeic acid, chlorogenic acid and ferulic acid, and esters and pharmaceutically acceptable salts thereof; and (B) a component selected from the group consisting of central nervous system stimulating components, food fibers, extracts of perennial evergreen leaves of the genus Camellia, Theaceae, or Eucommia ulmoides Oliver, Eucommiae, organic acids having a molecular weight of 60 to 300 (excluding citric acid) and pharmaceutically acceptable salts thereof, and sugar alcohols.

    Agent for preventing, improving or treating hypertension
    8.
    发明申请
    Agent for preventing, improving or treating hypertension 审中-公开
    用于预防，改善或治疗高血压的药物

    公开(公告)号：US20050281897A1

    公开(公告)日：2005-12-22

    申请号：US11209672

    申请日：2005-08-24

    申请人： Atsushi Suzuki ,  Ryuji Ochiai ,  Ichiro Tokimitsu

    发明人： Atsushi Suzuki ,  Ryuji Ochiai ,  Ichiro Tokimitsu

    IPC分类号： A61K31/19 ,  A61K31/192 ,  A61K31/216 ,  A61K31/235 ,  A61K36/81 ,  A61K36/82 ,  A61P9/12 ,  A61K35/78

    CPC分类号： A61K31/19 ,  A61K31/192 ,  A61K36/67 ,  A61K36/81 ,  A61K36/82 ,  A61K36/906 ,  A61K2300/00

    摘要： The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension. The agent for preventing, improving or treating hypertension contains the following components (A) and (B): (A) a compound selected from the group consisting of caffeic acid, chlorogenic acid and ferulic acid, and esters and pharmaceutically acceptable salts thereof; and (B) a component selected from the group consisting of central nervous system stimulating components, food fibers, extracts of perennial evergreen leaves of the genus Camellia, Theaceae, or Eucommia ulmoides Oliver, Eucommiae, organic acids having a molecular weight of 60 to 300 (excluding citric acid) and pharmaceutically acceptable salts thereof, and sugar alcohols.

    摘要翻译： 本发明涉及一种用于预防，改善或治疗高血压的药物，其具有低血压作用，抑制血压升高和改善高血压，并且用于预防或改善不会成为每日摄取负担的高血压的食品具有 更高的抗高血压作用，在治疗高血压患者期间作为饮食有用。 用于预防，改善或治疗高血压的药物含有以下组分（A）和（B）：（A）选自咖啡酸，绿原酸和阿魏酸的化合物及其酯和药学上可接受的盐; 和（B）选自中枢神经系统刺激成分，食用纤维，山茶花多年生常绿叶提取物，禾本科或杜仲杜仲，杜仲，分子量为60〜300的有机酸的成分 （不含柠檬酸）及其药学上可接受的盐，以及糖醇。

    Preventive or remedy for hypertension
    9.
    发明申请
    Preventive or remedy for hypertension 有权
    预防或补救高血压

    公开(公告)号：US20050215632A1

    公开(公告)日：2005-09-29

    申请号：US11106428

    申请日：2005-04-15

    申请人： Atsushi Suzuki ,  Ryuji Ochiai ,  Ichiro Tokimitsu

    发明人： Atsushi Suzuki ,  Ryuji Ochiai ,  Ichiro Tokimitsu

    IPC分类号： A61K31/12 ,  A61K31/216 ,  A61K31/235 ,  A61P9/12

    CPC分类号： A61K31/216 ,  A61K31/12 ,  A61K31/235

    摘要： Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): wherein, R1 and R2 are the same or different and each independently represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl, aryl, alkylaryl, aralkyl, or acyl, R3 represents hydroxyl, ester bond residue, or amide bond residue, R4 represents ester bond residue or amide bond residue, or a pharmaceutically acceptable salt thereof (except ferulic acid). When the preventive or remedy for hypertension according to the present invention is administered, ferulic acid exists in the blood for a long period of time, thereby continuously suppressing a blood pressure rise. Moreover, the hypertension preventive or remedy according to the present invention has reduced in bitterness peculiar to ferulic acid, which enables patients to take it continuously.

    摘要翻译： 提供一种治疗高血压的方法，其包括给予有效量的由下式（1）或（2）表示的化合物：其中R 1和R 2 2 >相同或不同，并且各自独立地表示氢，烷基，烯基，环烷基，环烯基，烷氧基烷基，芳基，烷基芳基，芳烷基或酰基，R 3表示羟基，酯键残基或酰胺键 残基R 4表示酯键残基或酰胺键残基，或其药学上可接受的盐（阿魏酸除外）。 当施用根据本发明的高血压的预防或治疗方法时，阿魏酸长期存在于血液中，从而持续抑制血压升高。 此外，根据本发明的高血压预防或治疗方法已经降低了阿魏酸特有的苦味，这使患者能够连续服用。

    Preventive or remedy for hypertension
    10.
    发明授权
    Preventive or remedy for hypertension 失效

    公开(公告)号：US06894077B2

    公开(公告)日：2005-05-17

    申请号：US10161739

    申请日：2002-06-05

    申请人： Atsushi Suzuki ,  Ryuji Ochiai ,  Ichiro Tokimitsu

    发明人： Atsushi Suzuki ,  Ryuji Ochiai ,  Ichiro Tokimitsu

    IPC分类号： A61K31/12 ,  A61K31/216 ,  A61K31/235 ,  A61P9/12 ,  A61K31/24

    CPC分类号： A61K31/216 ,  A61K31/12 ,  A61K31/235

    摘要： Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): wherein, R1 and R2 are the same or different and each independently represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl, aryl, alkylaryl, aralkyl, or acyl, R3 represents hydroxyl, ester bond residue, or amide bond residue, R4 represents ester bond residue or amide bond residue, or a pharmaceutically acceptable salt thereof (except ferulic acid). When the preventive or remedy for hypertension according to the present invention is administered, ferulic acid exists in the blood for a long period of time, thereby continuously suppressing a blood pressure rise. Moreover, the hypertension preventive or remedy according to the present invention has reduced in bitterness peculiar to ferulic acid, which enables patients to take it continuously.