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公开(公告)号：US20210381895A1
公开(公告)日：2021-12-09
申请号：US17406863
申请日：2021-08-19
Inventor： Daejong Yang , Hyunjun Cho , Youngzoon Yoon , Hyuck Choo
Abstract: A substrate for sensing, a method of manufacturing the substrate, and an analyzing apparatus including the substrate are provided. The substrate for sensing includes: a support layer; a plurality of metal nanoparticle clusters arranged on the support layer; and a plurality of perforations arranged among the plurality of metal nanoparticle clusters. The plurality of metal nanoparticle clusters each comprise a plurality of metal nanoparticles stacked in a three-dimensional structure. Each of the plurality of perforations transmits incident light therethrough.
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公开(公告)号：US12000735B2
公开(公告)日：2024-06-04
申请号：US17406863
申请日：2021-08-19
Inventor： Daejong Yang , Hyunjun Cho , Youngzoon Yoon , Hyuck Choo
CPC classification number: G01J3/4412 , B81C1/00206 , B82Y15/00 , B82Y30/00 , C23C18/06 , C23C18/08 , G01N21/658 , B81B2203/0361 , B81B2207/056 , B81C2201/0104
Abstract: A substrate for sensing, a method of manufacturing the substrate, and an analyzing apparatus including the substrate are provided. The substrate for sensing includes: a support layer; a plurality of metal nanoparticle clusters arranged on the support layer; and a plurality of perforations arranged among the plurality of metal nanoparticle clusters. The plurality of metal nanoparticle clusters each comprise a plurality of metal nanoparticles stacked in a three-dimensional structure. Each of the plurality of perforations transmits incident light therethrough.
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公开(公告)号：US10859499B2
公开(公告)日：2020-12-08
申请号：US15986246
申请日：2018-05-22
Inventor： Jeongoen Lee , Daejong Yang , Youngzoon Yoon , Hyuck Choo
IPC: G01N21/65
Abstract: An apparatus and method for quantitatively sensing and analyzing a concentration of biomolecules using Raman peak shift are disclosed. The quantitative molecular sensing apparatus includes an illumination optical system including a light source configured to irradiate excitation light onto an object, a detection optical system including an optical detector configured to detect light scattered from the object, and a signal processor configured to analyze properties of the object based on signal output by the detection optical system and to calculate a concentration of target molecules in the object based on a Raman peak shift value over a predetermined time period.
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公开(公告)号：US11125620B2
公开(公告)日：2021-09-21
申请号：US15989983
申请日：2018-05-25
Inventor： Daejong Yang , Hyunjun Cho , Youngzoon Yoon , Hyuck Choo
Abstract: A substrate for sensing, a method of manufacturing the substrate, and an analyzing apparatus including the substrate are provided. The substrate for sensing includes: a support layer; a plurality of metal nanoparticle clusters arranged on the support layer; and a plurality of perforations arranged among the plurality of metal nanoparticle clusters. The plurality of metal nanoparticle clusters each comprise a plurality of metal nanoparticles stacked in a three-dimensional structure. Each of the plurality of perforations transmits incident light therethrough.
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5.发明申请公开(公告)号：US20180078902A1
公开(公告)日：2018-03-22
申请号：US15710774
申请日：2017-09-20
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Daniel L. Magley , Vinayak Narasimhan , Hyuck Choo
CPC classification number: B01D61/427 , A61B5/14503 , A61B5/14532 , A61B5/6861 , A61B5/6876 , A61M5/142 , A61M5/14276 , F03B17/00 , F05B2210/11 , H01M4/92 , H01M4/96 , H01M8/16 , H01M12/08
Abstract: Systems, methods and devices are provided for electro-osmotic propulsion in a microfluidic environment. These systems, methods and devices can include a body having a channel comprising a pair of open ends, and a plurality of electrodes coupled to the body, wherein the electrodes are configured to generate a voltage and cause an electro-osmotic flow of a fluid through the channel. In many of the embodiments, an on-board power supply coupled to the body is provided for generating voltage across the electrodes. In some embodiments, the channel comprises a cylindrical shape having a circular cross-sectional area.
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Patent Agency Ranking
公开(公告)号：US20170164831A1
公开(公告)日：2017-06-15
申请号：US15364106
申请日：2016-11-29
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Hyuck Choo , Ashwin Balakrishna , Oliver Chen , Kun Ho Kim , Jeongoen Lee , Vinayak Narasimhan , Haeri Park
CPC classification number: A61B3/16 , A61B3/0008 , A61B2562/0285
Abstract: IOP sensors and IOP measurement algorithms are disclosed herein. Examples of the IOP measurement algorithm can include a signal demodulation and artificial neural network algorithm to produce reliable results using minimal computational resources. The overall accuracy and speed of the IOP sensors and measurement algorithms enable their implementation in home-based IOP measurement systems.
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公开(公告)号：US11170625B2
公开(公告)日：2021-11-09
申请号：US16417525
申请日：2019-05-20
Inventor： Robert H. Grubbs , Hyuck Choo , Frank L. Brodie
Abstract: A position sensing system comprises a position sensor having an accelerometer and a gyroscope, an alarm, and a controller configured to receive data from the position sensor and activate the alarm according to alarm management instructions stored in a memory. In some embodiments, the alarm instructions include a snooze option to allow the user/patient to temporarily deactivate the alarm. The controller is communicably linked to a remote display device configured to display the orientation of the user's body part.
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公开(公告)号：US20200051415A1
公开(公告)日：2020-02-13
申请号：US16417525
申请日：2019-05-20
Inventor： Robert H. Grubbs , Hyuck Choo , Frank L. Brodie
Abstract: A position sensing system comprises a position sensor having an accelerometer and a gyroscope, an alarm, and a controller configured to receive data from the position sensor and activate the alarm according to alarm management instructions stored in a memory. In some embodiments, the alarm instructions include a snooze option to allow the user/patient to temporarily deactivate the alarm. The controller is communicably linked to a remote display device configured to display the orientation of the user's body part.
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公开(公告)号：US10426341B2
公开(公告)日：2019-10-01
申请号：US14868219
申请日：2015-09-28
Inventor： Hyuck Choo , David Sretavan
Abstract: Systems and methods of sensing intraocular pressure are described. An example miniaturized intraocular pressure (IOP) monitoring system is provided using a nanophotonics-based implantable IOP sensor with remote optical readout that can be adapted for both patient and research use. A handheld detector optically excites the pressure-sensitive nanophotonic structure of the IOP-sensing implant placed in the anterior chamber and detects the reflected light, whose optical signature changes as a function of IOP. Optical detection eliminates the need for large, complex LC structures and simplifies sensor design. The use of nanophotonic components improves the sensor's resolution and sensitivity, increases optical readout distance, and reduces its size by a factor of 10-30 over previous implants. Its small size and convenient optical readout allows frequent and accurate self-tracking of IOP by patients in home settings.
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10.发明授权公开(公告)号：US11154226B2
公开(公告)日：2021-10-26
申请号：US15179744
申请日：2016-06-10
Inventor： Yu-Chong Tai , Hyuck Choo , Ramiro Magalhaes Ribeiro , Mark S. Humayun
IPC: A61B5/00 , A61B5/145 , A61B5/1459 , G02B6/10 , G02B6/122 , G01J3/44 , G01N21/65 , G02B6/34 , G01N21/64 , G02B6/12
Abstract: A medical sensor is described. In an example, the medical sensor includes a nanoscale tapered waveguide attached to a substrate. The nanoscale tapered waveguide includes a nanoscale channel that receives fluid and an excitation light and that outputs a response light. The excitation light propagates through the fluid. A receiving channel of the nanoscale channel is configured as a waveguide that receives and guides the excitation to a linearly tapered channel of the nanoscale channel. The linearly tapered channel has three dimensional linear tapering that focuses the excitation light guided from the receiving channel into an optical response channel of the nanoscale channel. In turn, the optical response channel is configured as a waveguide that outputs a response light in response to the excitation light focused from the linearly tapered channel. The response light corresponds to a response of an analyte of the fluid present in the optical response channel.
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