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公开(公告)号：US08252164B2
公开(公告)日：2012-08-28
申请号：US13113680
申请日：2011-05-23
申请人： Samuel Martin , Xiangfeng Duan , Katsumasa Fujii , James M. Hamilton , Hiroshi Iwata , Francisco Leon , Jeffrey Miller , Tetsu Negishi , Hiroshi Ohki , J. Wallace Parce , Cheri X. Y. Pereira , Paul John Schuele , Akihide Shibata , David P. Stumbo , Yasunobu Okada
发明人： Samuel Martin , Xiangfeng Duan , Katsumasa Fujii , James M. Hamilton , Hiroshi Iwata , Francisco Leon , Jeffrey Miller , Tetsu Negishi , Hiroshi Ohki , J. Wallace Parce , Cheri X. Y. Pereira , Paul John Schuele , Akihide Shibata , David P. Stumbo , Yasunobu Okada
IPC分类号： C25D13/02
CPC分类号： H01L29/0665 , B82B3/00 , B82Y10/00 , B82Y30/00 , B82Y40/00 , H01L29/0673 , Y10S977/883
摘要： The present invention provides methods and systems for nanowire alignment and deposition. Energizing (e.g., an alternating current electric field) is used to align and associate nanowires with electrodes. By modulating the energizing, the nanowires are coupled to the electrodes such that they remain in place during subsequent wash and drying steps. The invention also provides methods for transferring nanowires from one substrate to another in order to prepare various device substrates. The present invention also provides methods for monitoring and controlling the number of nanowires deposited at a particular electrode pair, as well as methods for manipulating nanowires in solution.
摘要翻译： 本发明提供了用于纳米线对准和沉积的方法和系统。 使用通电（例如，交流电场）来使纳米线与电极对准和关联。 通过调节激励，纳米线耦合到电极，使得它们在随后的洗涤和干燥步骤期间保持在适当的位置。 本发明还提供了将纳米线从一个衬底转移到另一个衬底以便制备各种器件衬底的方法。 本发明还提供了用于监测和控制在特定电极对上沉积的纳米线的数量的方法，以及用于操纵溶液中的纳米线的方法。
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公开(公告)号：US07968474B2
公开(公告)日：2011-06-28
申请号：US11979949
申请日：2007-11-09
申请人： Samuel Martin , Xiangfeng Duan , Katsumasa Fujii , James M. Hamilton , Hiroshi Iwata , Francisco Leon , Jeffrey Miller , Tetsu Negishi , Hiroshi Ohki , J. Wallace Parce , Cheri X. Y. Pereira , Paul John Schuele , Akihide Shibata , David P. Stumbo , Yasunobu Okada
发明人： Samuel Martin , Xiangfeng Duan , Katsumasa Fujii , James M. Hamilton , Hiroshi Iwata , Francisco Leon , Jeffrey Miller , Tetsu Negishi , Hiroshi Ohki , J. Wallace Parce , Cheri X. Y. Pereira , Paul John Schuele , Akihide Shibata , David P. Stumbo , Yasunobu Okada
IPC分类号： H01L21/71
CPC分类号： H01L29/0665 , B82B3/00 , B82Y10/00 , B82Y30/00 , B82Y40/00 , H01L29/0673 , Y10S977/883
摘要： The present invention provides methods and systems for nanowire alignment and deposition. Energizing (e.g., an alternating current electric field) is used to align and associate nanowires with electrodes. By modulating the energizing, the nanowires are coupled to the electrodes such that they remain in place during subsequent wash and drying steps. The invention also provides methods for transferring nanowires from one substrate to another in order to prepare various device substrates. The present invention also provides methods for monitoring and controlling the number of nanowires deposited at a particular electrode pair, as well as methods for manipulating nanowires in solution.
摘要翻译： 本发明提供了用于纳米线对准和沉积的方法和系统。 使用通电（例如，交流电场）来使纳米线与电极对准和关联。 通过调节激励，纳米线耦合到电极，使得它们在随后的洗涤和干燥步骤期间保持在适当的位置。 本发明还提供了将纳米线从一个衬底转移到另一个衬底以便制备各种器件衬底的方法。 本发明还提供了用于监测和控制在特定电极对上沉积的纳米线的数量的方法，以及用于操纵溶液中的纳米线的方法。
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公开(公告)号：US20080224123A1
公开(公告)日：2008-09-18
申请号：US11979949
申请日：2007-11-09
申请人： Samuel Martin , Xiangfeng Duan , Katsumasa Fujii , James M. Hamilton , Hiroshi Iwata , Francisco Leon , Jeffrey Miller , Tetsu Negishi , Hiroshi Ohki , J. Wallace Parce , Cheri X.Y. Pereira , Paul John Schuele , Akihide Shibata , David P. Stumbo , Yasunobu Okada
发明人： Samuel Martin , Xiangfeng Duan , Katsumasa Fujii , James M. Hamilton , Hiroshi Iwata , Francisco Leon , Jeffrey Miller , Tetsu Negishi , Hiroshi Ohki , J. Wallace Parce , Cheri X.Y. Pereira , Paul John Schuele , Akihide Shibata , David P. Stumbo , Yasunobu Okada
IPC分类号： H01L31/00 , H01L21/326
CPC分类号： H01L29/0665 , B82B3/00 , B82Y10/00 , B82Y30/00 , B82Y40/00 , H01L29/0673 , Y10S977/883
摘要： The present invention provides methods and systems for nanowire alignment and deposition. Energizing (e.g., an alternating current electric field) is used to align and associate nanowires with electrodes. By modulating the energizing, the nanowires are coupled to the electrodes such that they remain in place during subsequent wash and drying steps. The invention also provides methods for transferring nanowires from one substrate to another in order to prepare various device substrates. The present invention also provides methods for monitoring and controlling the number of nanowires deposited at a particular electrode pair, as well as methods for manipulating nanowires in solution.
摘要翻译： 本发明提供了用于纳米线对准和沉积的方法和系统。 使用通电（例如，交流电场）来使纳米线与电极对准和关联。 通过调节激励，纳米线耦合到电极，使得它们在随后的洗涤和干燥步骤期间保持在适当的位置。 本发明还提供了将纳米线从一个衬底转移到另一个衬底以便制备各种器件衬底的方法。 本发明还提供了用于监测和控制在特定电极对上沉积的纳米线的数量的方法，以及用于操纵溶液中的纳米线的方法。
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公开(公告)号：US20110284380A1
公开(公告)日：2011-11-24
申请号：US13113680
申请日：2011-05-23
申请人： Samuel MARTIN , Xiangfeng Duan , Katsumasa Fujii , James M. Hamilton , Hiroshi Iwata , Francisco Leon , Jeffrey Miller , Tetsu Negishi , Hiroshi Ohki , J. Wallace Parce , Cheri X.Y. Pereira , Paul John Schuele , Akihide Shibata , David P. Stumbo , Yasunobu Okada
发明人： Samuel MARTIN , Xiangfeng Duan , Katsumasa Fujii , James M. Hamilton , Hiroshi Iwata , Francisco Leon , Jeffrey Miller , Tetsu Negishi , Hiroshi Ohki , J. Wallace Parce , Cheri X.Y. Pereira , Paul John Schuele , Akihide Shibata , David P. Stumbo , Yasunobu Okada
CPC分类号： H01L29/0665 , B82B3/00 , B82Y10/00 , B82Y30/00 , B82Y40/00 , H01L29/0673 , Y10S977/883
摘要： The present invention provides methods and systems for nanowire alignment and deposition. Energizing (e.g., an alternating current electric field) is used to align and associate nanowires with electrodes. By modulating the energizing, the nanowires are coupled to the electrodes such that they remain in place during subsequent wash and drying steps. The invention also provides methods for transferring nanowires from one substrate to another in order to prepare various device substrates. The present invention also provides methods for monitoring and controlling the number of nanowires deposited at a particular electrode pair, as well as methods for manipulating nanowires in solution.
摘要翻译： 本发明提供了用于纳米线对准和沉积的方法和系统。 使用通电（例如，交流电场）来使纳米线与电极对准和关联。 通过调节激励，纳米线耦合到电极，使得它们在随后的洗涤和干燥步骤期间保持在适当的位置。 本发明还提供了将纳米线从一个衬底转移到另一个衬底以便制备各种器件衬底的方法。 本发明还提供了用于监测和控制在特定电极对上沉积的纳米线的数量的方法，以及用于操纵溶液中的纳米线的方法。
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5.发明申请SEMICONDUCTOR ELEMENT, METHOD OF MANUFACTURING FINE STRUCTURE ARRANGING SUBSTRATE, AND DISPLAY ELEMENT 审中-公开半导体元件，制造微结构基板的方法和显示元件公开(公告)号：US20110058126A1
公开(公告)日：2011-03-10
申请号：US12867725
申请日：2009-02-10
申请人： Yasunobu Okada , Akihide Shibata , Yoshiharu Nakajima , Hiroshi Iwata , Ai Naitou , Yutaka Takafuji , Tetsu Negishi
发明人： Yasunobu Okada , Akihide Shibata , Yoshiharu Nakajima , Hiroshi Iwata , Ai Naitou , Yutaka Takafuji , Tetsu Negishi
IPC分类号： G02F1/1333 , H01L29/41 , H01L21/44
CPC分类号： H01L27/283 , H01L29/0665 , H01L29/0673 , H01L29/78696 , H01L51/0012 , H01L51/0545
摘要： With reference to a direction perpendicular to a direction of forming electrodes to which a voltage can be applied, fine structures are each arranged within ±5 degrees at a substantially even interval, and a semiconductor element is formed by using the fine structures. On an insulating substrate, at least two electrodes are arranged at a predetermined interval, and there are formed one or more fine structure arranging regions, each of which is formed by a unit of the two electrodes. A semiconductor element electrode is made in contact with the plurality of the fine structures, each having two ends in contact with the two electrodes and a length in a longitudinal direction of a nano order to a micron order, and arranged within ±5 degrees with reference to the direction perpendicular to the direction of forming the electrodes.
摘要翻译： 关于与形成可施加电压的电极的方向垂直的方向，精细结构以基本上均匀的间隔布置在±5度内，并且通过使用精细结构形成半导体元件。 在绝缘基板上，至少两个电极以预定间隔布置，并且形成一个或多个精细结构布置区域，每个电极由两个电极的单元形成。 半导体元件电极与多个精细结构接触，每个微结构具有与两个电极接触的两个端部，并且在纵向方向上的长度为纳米级至微米级，并且以参考方式布置在±5度内 到垂直于形成电极的方向的方向。
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6.发明授权Method for aligning microscopic structures and substrate having microscopic structures aligned, as well as integrated circuit apparatus and display element 有权用于对准具有微观结构的微观结构和基板的方法，以及集成电路设备和显示元件公开(公告)号：US08216440B2
公开(公告)日：2012-07-10
申请号：US12081018
申请日：2008-04-09
申请人： Akihide Shibata , Yasunobu Okada
发明人： Akihide Shibata , Yasunobu Okada
IPC分类号： C25D1/12
CPC分类号： C25D13/02 , C25D13/18 , H01L21/76838 , H01L23/544 , H01L29/0665 , H01L29/0673 , H01L29/78696 , H01L2221/1094 , H01L2924/0002 , H01L2924/19043 , H01L2924/00
摘要： An object of the present invention is to implement a method for aligning microscopic structures in desired locations and in a desired direction, in order to align microscopic structures, such as nanostructures, with high precision. The method includes a substrate forming step of forming three electrodes to which independent potentials can be applied, a microscopic structure liquid applying step of applying a liquid in which microscopic structures are dispersed to the insulating substrate, and a microscopic structure aligning step of applying respective voltages to the three electrodes to align the microscopic structures in locations defined by the electrodes.
摘要翻译： 本发明的一个目的是实现一种用于在所需位置和期望方向上对准微观结构的方法，以便以高精度对准微结构，例如纳米结构。 该方法包括形成能够施加独立电位的三个电极的基板形成步骤，将微细结构分散在其中的液体施加到绝缘基板的微结构液体施加步骤，以及施加各个电压的微观结构对准步骤 到三个电极以将微观结构对准由电极限定的位置。
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7.发明申请Method for aligning microscopic structures and substrate having microscopic structures aligned, as well as integrated circuit apparatus and display element 有权用于对准具有微观结构的微观结构和基板的方法，以及集成电路设备和显示元件公开(公告)号：US20080251381A1
公开(公告)日：2008-10-16
申请号：US12081018
申请日：2008-04-09
申请人： Akihide Shibata , Yasunobu Okada
发明人： Akihide Shibata , Yasunobu Okada
IPC分类号： C25D1/12
CPC分类号： C25D13/02 , C25D13/18 , H01L21/76838 , H01L23/544 , H01L29/0665 , H01L29/0673 , H01L29/78696 , H01L2221/1094 , H01L2924/0002 , H01L2924/19043 , H01L2924/00
摘要： An object of the present invention is to implement a method for aligning microscopic structures in desired locations and in a desired direction, in order to align microscopic structures, such as nanostructures, with high precision. The method includes a substrate forming step of forming three electrodes to which independent potentials can be applied, a microscopic structure liquid applying step of applying a liquid in which microscopic structures are dispersed to the insulating substrate, and a microscopic structure aligning step of applying respective voltages to the three electrodes to align the microscopic structures in locations defined by the electrodes.
摘要翻译： 本发明的一个目的是实现一种用于在所需位置和期望方向上对准微观结构的方法，以便以高精度对准微结构，例如纳米结构。 该方法包括形成能够施加独立电位的三个电极的基板形成步骤，将微细结构分散在其中的液体施加到绝缘基板的微结构液体施加步骤，以及施加各个电压的微观结构对准步骤 到三个电极以将微观结构对准由电极限定的位置。
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公开(公告)号：US20050003455A1
公开(公告)日：2005-01-06
申请号：US10486233
申请日：2002-08-07
申请人： Yasunobu Okada , Shigeru Tanabe
发明人： Yasunobu Okada , Shigeru Tanabe
CPC分类号： G01N33/6872 , A61K31/00 , G01N33/5008 , G01N33/5061 , G01N33/5064 , G01N2500/10 , G01N2510/00
摘要： This invention aims at providing a method of searching for substances that can selectively suppress apoptosis in cardiovascular cells. This objective is attained by providing a method of screening for therapeutic and/or prophylactic agents of cardiac disease, which comprises the steps of inducing apoptosis in cultured myocardial cells and/or cultured vascular endothelial cells; treating the cells with a Cl− channel blocker under test; and evaluating the therapeutic and/or prophylactic effect of the blocker under test on cardiac disease by checking to see if it can suppress apoptotic cell death in the cardiovascular cells or vascular endothelial cells.
摘要翻译： 本发明旨在提供一种能够选择性抑制心血管细胞凋亡的物质的方法。 该目的通过提供筛选心脏病治疗和/或预防药物的方法来实现，其包括在培养的心肌细胞和/或培养的血管内皮细胞中诱导细胞凋亡的步骤; 用被测试的Cl - 通道阻断剂处理细胞; 以及通过检查其是否可以抑制心血管细胞或血管内皮细胞中的凋亡性细胞死亡来评估受试者中的心脏病的治疗和/或预防效果。
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9.发明申请Method for inhibiting cell death, cell death inhibitor, and remedy for disease caused by cell death containing the cell death inhibitor 审中-公开用于抑制细胞死亡，细胞死亡抑制剂和由含有细胞死亡抑制剂的细胞死亡引起的疾病的治疗方法公开(公告)号：US20060088552A1
公开(公告)日：2006-04-27
申请号：US10536797
申请日：2003-11-27
IPC分类号： A61K39/02
CPC分类号： A61K38/164
摘要： A method according to the present invention for inhibiting cell death includes administrating an anion channel-forming peptide to cells under lactacidosis. The anion channel-forming peptide forms an anion channel on a cell membrane artificially. A cell death inhibitor according to the present invention contains the anion channel-forming peptide. Some of examples of the anion channel-forming peptide are a VacA protein derived from Helicobacter pylori and a glycine receptor channel variant peptide. The method and cell death inhibitor according to the present invention are effective especially for necrotic cell death that accompanies cell swelling.
摘要翻译： 根据本发明的用于抑制细胞死亡的方法包括将阴离子通道形成肽施用于乳酸脱氢酶下的细胞。 阴离子通道形成肽人造细胞膜上形成阴离子通道。 根据本发明的细胞死亡抑制剂含有阴离子通道形成肽。 阴离子通道形成肽的一些实例是来自幽门螺杆菌和甘氨酸受体通道变体肽的VacA蛋白。 根据本发明的方法和细胞死亡抑制剂特别适用于伴随细胞肿胀的坏死细胞死亡。
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