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公开(公告)号：US08417474B2
公开(公告)日：2013-04-09
申请号：US11702404
申请日：2007-02-05
申请人： Saswati Datta , William Randal Belcher , Sandra Lou Murawski , Mannie Lee Clapp , Steven Hardy Page , Magda El-Nokaly , Richard Tweddell, III , Sohini Paldey , Louis Fay Wong , Ronald R. Warner , Kerstin Ann-Margret Nolkrantz , Chitra Laxmanan , Brian Naveen Ranade , Jianjun Justin Li , Randall Glenn Marsh , Maria Montserrat Sanchez Peña
发明人： Saswati Datta , William Randal Belcher , Sandra Lou Murawski , Mannie Lee Clapp , Steven Hardy Page , Magda El-Nokaly , Richard Tweddell, III , Sohini Paldey , Louis Fay Wong , Ronald R. Warner , Kerstin Ann-Margret Nolkrantz , Chitra Laxmanan , Brian Naveen Ranade , Jianjun Justin Li , Randall Glenn Marsh , Maria Montserrat Sanchez Peña
CPC分类号： G01N19/02 , G01N2030/025 , G01N2203/0246
摘要： Method of product evaluation comprising the steps of applying at least one substance to a surface of an artificial substrate to form a substance-coated surface, wherein the substrate surface demonstrates at least one physical property selected from the group consisting of a total surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a polar component of the total surface energy of from about 0 mJ/m2 to about 15 mJ/m2, a zeta-potential at a pH of about 5.0 of from about −30 mV to about 30 mV, and combinations thereof, and performing at least one analysis of the substance-coated surface.
摘要翻译： 产品评估方法包括以下步骤：将至少一种物质施加到人造基底的表面以形成物质涂覆的表面，其中所述基底表面显示出至少一种物理性质，所述物理性质选自以下物质的总表面能： 约15mJ / m 2至约50mJ / m 2，总表面能的极性分数为约0mJ / m 2至约15mJ / m 2，pH约5.0的ζ电位为约-30mV 至约30mV，及其组合，并进行至少一种物质涂覆表面的分析。
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公开(公告)号：US08202319B2
公开(公告)日：2012-06-19
申请号：US13095731
申请日：2011-04-27
申请人： William Randal Belcher , Mannie Lee Clapp , Saswati Datta , Magda El-Nokaly , Sandra Lou Murawski , Steven Hardy Page , Sohini Paldey , Ronald Ray Warner , Raphael Warren
发明人： William Randal Belcher , Mannie Lee Clapp , Saswati Datta , Magda El-Nokaly , Sandra Lou Murawski , Steven Hardy Page , Sohini Paldey , Ronald Ray Warner , Raphael Warren
IPC分类号： A61F2/10 , B32B3/00 , B32B33/00 , B32B27/40 , C07C211/21 , C07C33/02 , C07C22/00 , C07C11/00 , C09D7/00
CPC分类号： C08J7/065 , A61L27/28 , A61L27/50 , A61L2400/18 , B82Y30/00 , C08J2375/04 , Y10T428/24479 , Y10T428/24802 , Y10T428/26 , Y10T428/31551 , Y10T442/2525
摘要： Article of manufacture comprising a substrate and a coating layer. The coating layer comprises at least one coating material, and is stably affixed to the substrate to form a stable, coated surface. The coated surface has a texture that mimics the topography of mammalian keratinous tissue and demonstrates at least one physical property representative of mammalian keratinous tissue, selected from the group consisting of a total surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a dispersive component of the surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a polar component of the total surface energy of from about 1 mJ/m2 to about 14 mJ/m2, a zeta-potential at a pH of about 5.0 of from about −40 mV to about 30 mV, and combinations thereof.
摘要翻译： 包括基材和涂层的制品。 涂层包括至少一种涂层材料，并且稳定地固定到基底上以形成稳定的涂覆表面。 涂覆的表面具有模拟哺乳动物角质组织的形貌的纹理，并且显示代表哺乳动物角质组织的至少一种物理性质，其选自总表面能为约15mJ / m 2至约50mJ / m 2 表面能的分散组分为约15mJ / m 2至约50mJ / m 2，总表面能的极性分数为约1mJ / m 2至约14mJ / m 2，ζ电位为 大约5.0的pH为约-40mV至约30mV，及其组合。
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公开(公告)号：US20110202134A1
公开(公告)日：2011-08-18
申请号：US13095731
申请日：2011-04-27
申请人： William Randal Belcher , Mannie Lee Clapp , Saswati Datta , Magda El-Nokaly , Sandra Lou Murawski , Steven Hardy Page , Sohini Paldey , Ronald Ray Warner , Raphael Warren
发明人： William Randal Belcher , Mannie Lee Clapp , Saswati Datta , Magda El-Nokaly , Sandra Lou Murawski , Steven Hardy Page , Sohini Paldey , Ronald Ray Warner , Raphael Warren
IPC分类号： A61F2/10 , B32B3/00 , B32B33/00 , C07C211/21 , C07C33/02 , C07C22/00 , C09D7/00 , B32B27/40 , C07C11/00
CPC分类号： C08J7/065 , A61L27/28 , A61L27/50 , A61L2400/18 , B82Y30/00 , C08J2375/04 , Y10T428/24479 , Y10T428/24802 , Y10T428/26 , Y10T428/31551 , Y10T442/2525
摘要： Article of manufacture comprising a substrate and a coating layer. The coating layer comprises at least one coating material, and is stably affixed to the substrate to form a stable, coated surface. The coated surface has a texture that mimics the topography of mammalian keratinous tissue and demonstrates at least one physical property representative of mammalian keratinous tissue, selected from the group consisting of a total surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a dispersive component of the surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a polar component of the total surface energy of from about 1 mJ/m2 to about 14 mJ/m2, a zeta-potential at a pH of about 5.0 of from about −40 mV to about 30 mV, and combinations thereof.
摘要翻译： 包括基材和涂层的制品。 涂层包括至少一种涂层材料，并且稳定地固定到基底上以形成稳定的涂覆表面。 涂覆的表面具有模拟哺乳动物角质组织的形貌的纹理，并且显示代表哺乳动物角质组织的至少一种物理性质，其选自总表面能为约15mJ / m 2至约50mJ / m 2 表面能的分散组分为约15mJ / m 2至约50mJ / m 2，总表面能的极性分数为约1mJ / m 2至约14mJ / m 2，ζ电位为 大约5.0的pH为约-40mV至约30mV，及其组合。
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公开(公告)号：US07954392B2
公开(公告)日：2011-06-07
申请号：US11502858
申请日：2006-08-11
申请人： William Randal Belcher , Mannie Lee Clapp , Saswati Datta , Magda El-Nokaly , Sandra Lou Murawski , Steven Hardy Page , Sohini Paldey , Ronald Ray Warner , Raphael Warren
发明人： William Randal Belcher , Mannie Lee Clapp , Saswati Datta , Magda El-Nokaly , Sandra Lou Murawski , Steven Hardy Page , Sohini Paldey , Ronald Ray Warner , Raphael Warren
IPC分类号： G01N33/00
CPC分类号： C08J7/065 , A61L27/28 , A61L27/50 , A61L2400/18 , B82Y30/00 , C08J2375/04 , Y10T428/24479 , Y10T428/24802 , Y10T428/26 , Y10T428/31551 , Y10T442/2525
摘要： Article of manufacture comprising a substrate and a coating layer. The coating layer comprises at least one coating material, and is stably affixed to the substrate to form a stable, coated surface. The coated surface has a texture that mimics the topography of mammalian keratinous tissue and demonstrates at least one physical property representative of mammalian keratinous tissue, selected from the group consisting of a total surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a dispersive component of the surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a polar component of the total surface energy of from about 1 mJ/m2 to about 14 mJ/m2, a zeta-potential at a pH of about 5.0 of from about −40 mV to about 30 mV, and combinations thereof.
摘要翻译： 包括基材和涂层的制品。 涂层包括至少一种涂层材料，并且稳定地固定到基底上以形成稳定的涂覆表面。 涂覆的表面具有模拟哺乳动物角质组织的形貌的纹理，并且显示代表哺乳动物角质组织的至少一种物理性质，其选自总表面能为约15mJ / m 2至约50mJ / m 2 表面能的分散组分为约15mJ / m 2至约50mJ / m 2，总表面能的极性分数为约1mJ / m 2至约14mJ / m 2，ζ电位为 大约5.0的pH为约-40mV至约30mV，及其组合。
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公开(公告)号：US20110060577A1
公开(公告)日：2011-03-10
申请号：US12873851
申请日：2010-09-01
IPC分类号： G06G7/60
CPC分类号： G09B23/30
摘要： In one embodiment, a method of modeling interactions with keratinous tissue may comprise the steps of providing a nonwoven mimic and performing an act on the mimic as may be performed on keratinous tissue. The nonwoven mimic has a surface energy representative of keratinous tissue. In another embodiment, a method of modeling interactions with keratinous tissue may comprise the steps of: providing a mimic comprising from about 60% or greater rayon, from about 40% or less polyester, and a surface energy representative of keratinous tissue; and performing an act on the mimic as may be performed on keratinous tissue. The mimic is preferably a nonwoven mimic.
摘要翻译： 在一个实施方案中，与角质组织相互作用建模的方法可以包括以下步骤：提供非织造模拟物并对可能对角质组织进行的模拟物进行作用。 非织造模拟物具有代表角质组织的表面能。 在另一个实施方案中，建模与角质组织的相互作用的方法可以包括以下步骤：提供包含约60％或更多人造丝，约40％或更少的聚酯和表示角质组织的表面能的模拟物; 并且可以对角质组织进行对模拟物的作用。 模拟物优选是非织造模拟物。
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公开(公告)号：US08468004B2
公开(公告)日：2013-06-18
申请号：US12873851
申请日：2010-09-01
CPC分类号： G09B23/30
摘要： In one embodiment, a method of modeling interactions with keratinous tissue may comprise the steps of providing a nonwoven mimic and performing an act on the mimic as may be performed on keratinous tissue. The nonwoven mimic has a surface energy representative of keratinous tissue. In another embodiment, a method of modeling interactions with keratinous tissue may comprise the steps of: providing a mimic comprising from about 60% or greater rayon, from about 40% or less polyester, and a surface energy representative of keratinous tissue; and performing an act on the mimic as may be performed on keratinous tissue. The mimic is preferably a nonwoven mimic.
摘要翻译： 在一个实施方案中，与角质组织相互作用建模的方法可以包括以下步骤：提供非织造模拟物并对可能对角质组织进行的模拟物进行作用。 非织造模拟物具有代表角质组织的表面能。 在另一个实施方案中，建模与角质组织的相互作用的方法可以包括以下步骤：提供包含约60％或更多人造丝，约40％或更少的聚酯和表示角质组织的表面能的模拟物; 并且可以对角质组织进行对模拟物的作用。 模拟物优选是非织造模拟物。
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7.发明授权Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a gel network 有权组合物，其包含微粒锌材料，吡啶硫酮或吡啶硫酮的多价金属盐和凝胶网络公开(公告)号：US09381382B2
公开(公告)日：2016-07-05
申请号：US11602770
申请日：2006-11-21
申请人： James Robert Schwartz , Eric Scott Johnson , Bonnie Theresa King , Carl Hinz Margraf, III , Gregory V. Tormos , David Thomas Warnke , Debora W. Chang , David Scott Dunlop , Kevin M. Labitzke , Sandra Lou Murawski , William Jeffrey Gore , Theodore Jay Verbrugge , Elizabeth Marie Marzonie Elsner , Jennifer Elaine Hilvert , Yingkun Jin , Brian Michael Hurley , Teresa Cuasay Manuel
发明人： James Robert Schwartz , Eric Scott Johnson , Bonnie Theresa King , Carl Hinz Margraf, III , Gregory V. Tormos , David Thomas Warnke , Debora W. Chang , David Scott Dunlop , Kevin M. Labitzke , Sandra Lou Murawski , William Jeffrey Gore , Theodore Jay Verbrugge , Elizabeth Marie Marzonie Elsner , Jennifer Elaine Hilvert , Yingkun Jin , Brian Michael Hurley , Teresa Cuasay Manuel
IPC分类号： A61K31/555 , A61K8/27 , A61K8/60 , A61K8/49 , A61Q5/00 , A61Q5/02 , A61Q5/12 , A61K8/02 , A61K8/04 , A61K8/34 , A61K8/36 , A61K8/37 , A61K8/39 , A61K8/41 , A61K8/42 , A61K8/46 , A61K8/73
CPC分类号： A61Q5/006 , A61K8/0295 , A61K8/042 , A61K8/27 , A61K8/342 , A61K8/361 , A61K8/37 , A61K8/375 , A61K8/39 , A61K8/416 , A61K8/42 , A61K8/463 , A61K8/49 , A61K8/4933 , A61K8/60 , A61K8/737 , A61K31/555 , A61Q5/00 , A61Q5/02 , A61Q5/12
摘要： The present invention relates to a composition comprising an effective amount of a particulate zinc material, an effective amount of a detersive surfactant including a surfactant with an anionic functional group, an effective amount of a pyrithione or a polyvalent metal salt of a pyrithione, a dispersed gel network phase comprising: i) at least about 0.05% of one or more fatty amphiphiles, by weight of said shampoo composition; ii) at least about 0.01% of one or more secondary surfactants, by weight of said shampoo composition; and iii) water; and at least about 20% of an aqueous carrier, by weight of said shampoo composition.
摘要翻译： 本发明涉及一种组合物，其包含有效量的颗粒状锌材料，有效量的去污表面活性剂，包括具有阴离子官能团的表面活性剂，有效量的吡啶硫酮或吡啶硫酮的多价金属盐，分散 凝胶网络相，其包含：i）按所述洗发剂组合物的重量计至少约0.05％的一种或多种脂肪两亲物; ii）按所述洗发剂组合物的重量计至少约0.01％的一种或多种次级表面活性剂; 和iii）水; 和至少约20％的所述洗发剂组合物的重量的水性载体。
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8.发明授权Composition comprising particulate zinc material with a high relative zinc lability 有权组合物包含具有高的相对锌不稳定性的颗粒状锌材料公开(公告)号：US09381148B2
公开(公告)日：2016-07-05
申请号：US11216520
申请日：2005-08-31
申请人： James Robert Schwartz , Eric Scott Johnson , Bonnie Theresa King , Carl Hinz Margraf, III , Gregory V. Tormos , David Thomas Warnke , Debora W. Chang , David Scott Dunlop , Kevin M. Labitzke , Sandra Lou Murawski , William Jeffrey Gore , Theodore Jay Verbrugge
发明人： James Robert Schwartz , Eric Scott Johnson , Bonnie Theresa King , Carl Hinz Margraf, III , Gregory V. Tormos , David Thomas Warnke , Debora W. Chang , David Scott Dunlop , Kevin M. Labitzke , Sandra Lou Murawski , William Jeffrey Gore , Theodore Jay Verbrugge
CPC分类号： A61K8/4933 , A61K8/27 , A61K31/44 , A61K33/30 , A61Q5/006 , A61K2300/00
摘要： The present invention relates to a composition comprising an effective amount of a particulate zinc material, an effective amount of a surfactant including a surfactant with an anionic functional group wherein the particulate zinc material has a relative zinc lability of greater than about 15 % and wherein the composition comprises less than 5.5 micromoles of a zinc binding material per gram of the particulate zinc material/per m2/gram surface area of the particulate zinc material.
摘要翻译： 本发明涉及一种组合物，其包含有效量的颗粒状锌材料，有效量的表面活性剂，其包括具有阴离子官能团的表面活性剂，其中所述颗粒状锌材料的相对锌含量大于约15％，并且其中 组合物包含小于5.5微摩尔的锌粘合材料/克的颗粒状锌材料/每m2 /克颗粒状锌材料的表面积。
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9.发明申请Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a synthetic cationic polymer 审中-公开组合物，其包含微粒锌材料，吡啶硫酮或吡啶硫酮的多价金属盐和合成的阳离子聚合物公开(公告)号：US20080206355A1
公开(公告)日：2008-08-28
申请号：US11890684
申请日：2007-08-07
申请人： James Robert Schwartz , Eric Scott Johnson , Bonnie Theresa King , Carl Hinz Margraf , Gregory V. Tomos , David Thomas Warnke , Deborah W. Chang , David Scott Dunlop , Kevin M. Labitzke , Sandra Lou Murawski , William Jeffrey Gore , Theodore Jay Verbrugge , Mark Anthony Brown , Timothy Woodrow Coffindaffer , Afua Asiedua Asante , Robert Lee Wells , Teresa Cuasay Manuel , Nicholas William Geary , Martin Asare
发明人： James Robert Schwartz , Eric Scott Johnson , Bonnie Theresa King , Carl Hinz Margraf , Gregory V. Tomos , David Thomas Warnke , Deborah W. Chang , David Scott Dunlop , Kevin M. Labitzke , Sandra Lou Murawski , William Jeffrey Gore , Theodore Jay Verbrugge , Mark Anthony Brown , Timothy Woodrow Coffindaffer , Afua Asiedua Asante , Robert Lee Wells , Teresa Cuasay Manuel , Nicholas William Geary , Martin Asare
CPC分类号： A61K8/27 , A61K8/4933 , A61K31/44 , A61K33/30 , A61K2800/5426 , A61Q5/006 , A61K2300/00
摘要： The present invention relates to a composition comprising a composition comprising an effective amount of a particulate zinc material; an effective amount of a surfactant including a surfactant with an anionic functional group; an effective amount of a pyrithione or a polyvalent metal salt of a pyrithione; from about 0.025% to about 5% by weight of a water soluble or dispersible, cationic, non-crosslinked, conditioning homopolymer having a cationic charge density of from about 2 meq/gm to about 10 meq/gm; and from about 20% to about 95% of an aqueous carrier, by weight of said composition
摘要翻译： 本发明涉及包含有效量的颗粒状锌材料的组合物的组合物; 有效量的表面活性剂，包括具有阴离子官能团的表面活性剂; 有效量的吡啶硫酮或吡啶硫酮的多价金属盐; 约0.025％至约5％重量的水溶性或可分散的阳离子非交联调理均聚物，其阳离子电荷密度为约2meq / gm至约10meq / gm; 和约20％至约95％的所述组合物的重量的水性载体
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