摘要:
An intramedullary drug delivery device is disclosed and can be inserted within a bone canal of a bone. The intramedullary drug delivery device can include a housing. A drug delivery region can be established along the housing. Also, the drug delivery region can be configured to substantially span a fracture within the bone.
摘要:
A bone cutting template is disclosed and can include a body. A plurality of grooves can be formed along the body and each groove can correspond to an incremental length of the body. The bone cutting template can include a plurality of length stamps along the body. Each of the plurality of length stamps can be adjacent to a corresponding groove.
摘要:
A therapeutic agent carrier for treating a defect in a bone is disclosed and can include a body that can be configured to approximate a portion of the bone. Further, the therapeutic agent carrier can include a plurality of grooves formed along the body. Each groove can correspond to an incremental length of the body. The therapeutic agent carrier can also include a plurality of dosage stamps along the body and each of the plurality of dosage stamps is adjacent to a corresponding to groove.
摘要:
Compound orthopedic implants, intervertebral prosthetic implants and methods of treating a patient are provided. In an exemplary embodiment, a compound orthopedic implant comprises a first conformable body and a second conformable body overlying the first conformable body. The compound orthopedic implant can function as a conformable carrier for delivering a therapeutic agent to an orthopedic site.
摘要:
Described is a medically useful article comprising a three-dimensional body including one or more implantable substances, wherein the body defines one or more reservoirs for receiving amounts of a biocompatible wetting liquid. In certain embodiments the body is disruptable upon wetting with the biocompatible liquid to form a conformable implantable material such as a putty, paste or more flowable wetted implant material. Also described are methods for manufacturing such medical materials, and methods for using such medical materials to treat patients.
摘要:
Described is an implantable medical material comprising a malleable, cohesive, shape-retaining putty including mineral particles, insoluble collagen fibers and soluble collagen. The medical material can be used in conjunction with biologically active factors such as osteogenic proteins to treat bone or other tissue defects in patients.
摘要:
A vertebral replacement device for supporting adjacent vertebrae includes a vertebral body member having at least one of an upper or lower disc replacement member engaged thereto at one end thereof. The disc replacement device can be positioned in a spinal disc space when disengaged from the vertebral body member.
摘要:
The invention relates, according to one embodiment, to a graft syringe assembly for delivering bone graft material is disclosed. The graft syringe assembly comprises a syringe subassembly including a syringe barrel having an inner chamber adapted for receiving bone graft material, a plunger adapted for expelling bone graft material from the inner chamber, the plunger slidably received within the inner chamber, and a syringe adapter coupled to the syringe barrel. The graft syringe assembly further comprises a connection subassembly coupled to the syringe adapter, and a delivery tube subassembly coupled to the connection subassembly, wherein the connection subassembly is configured to allow the delivery tube subassembly to rotate relative to the syringe subassembly.
摘要:
Methods and instruments are provided for performing spinal disc space preparation and implant insertion in minimally invasive procedures. The instruments include cutting instruments and implant insertion instruments adapted for insertion through a minimally invasive access portal to a spinal disc space. The proximal portions of the instruments are adapted to facilitate viewing through a proximal end opening of the access portal with the instruments positioned through the access portal while also enhancing the surgeon's control of the distal working end of the instruments while in the disc space.
摘要:
In certain described embodiments, implantable medical materials comprise a scaffolding material, a liquid organic binder, and entrapped calcium-containing particles. The medical materials can incorporate an osteoinductive factor such as a protein. The scaffolding material can bind the factor. In additional described embodiments, implantable medical materials include an osteoconductive scaffolding material, an incorporated osteoinductive factor, and a biodegradable barrier material effective to delay release of the factor from the scaffolding material. The scaffolding material can bind the factor. Also described a methods for preparing and implanting the described medical materials.