公开(公告)号：US09823207B2

公开(公告)日：2017-11-21

申请号：US13697132

申请日：2011-05-11

申请人： Sebastian Wieskotten ,  Tobias Groeber ,  Paul Chamney ,  Peter Wabel ,  Ulrich Moissl

发明人： Sebastian Wieskotten ,  Tobias Groeber ,  Paul Chamney ,  Peter Wabel ,  Ulrich Moissl

IPC分类号： B01D35/00 ,  G01N27/00 ,  A61M1/36 ,  G01N33/487

CPC分类号： G01N27/00 ,  A61M1/3626 ,  A61M1/3669 ,  A61M2205/3317 ,  G01N33/48735

摘要： Method and device according to the method for determining intracellular and/or extracellular, in particular macromolecular fractions of fluids, preferably of body fluids of living organisms, with the steps: coupling-in a measurement signal through an electrically non-conductive wall into the fluid to be measured; coupling-out an electrical measurement value that is thereby generated in the fluid to be measured; detecting the coupled-out electrical measurement value at a plurality of different frequencies of the electrical measurement signal; determining the intracellular and/or extracellular, in particular macromolecular fractions of the fluid to be measured by means of evaluation of the detected electrical measurement value at a plurality of frequencies of the measurement signal.

公开(公告)号：US20130277287A1

公开(公告)日：2013-10-24

申请号：US13991710

申请日：2011-12-09

申请人： Ulrich Moissl ,  Sebastian Wieskotten ,  Paul Chamney ,  Volker Nier ,  Peter Wabel

发明人： Ulrich Moissl ,  Sebastian Wieskotten ,  Paul Chamney ,  Volker Nier ,  Peter Wabel

IPC分类号： A61M1/16 ,  G06F19/00

CPC分类号： A61M1/16 ,  A61M1/1613 ,  A61M2205/52 ,  G06F19/00 ,  G06F19/34 ,  G06F19/3481 ,  G16H50/50

摘要： A method for calculating or estimating or approximating one or more values representing parameters of a patient includes the step of interpolating or extrapolating of at least one later value of a first parameter taking into account at least one earlier value of the first parameter, at least one earlier and at least one later value of a second parameter, and a mathematical relation between the first and the second parameter. An apparatus, a blood treatment device, a digital storage device, a computer program product, and a computer program are also described.

摘要翻译： 一种用于计算或估计或近似表示患者参数的一个或多个值的方法包括以下步骤：考虑到第一参数的至少一个较早的值，至少一个第一参数的至少一个以后的值来内插或外推第一参数的至少一个值 早期和至少一个后续值的第二参数，以及第一和第二参数之间的数学关系。 还描述了一种装置，血液处理装置，数字存储装置，计算机程序产品和计算机程序。

公开(公告)号：US20130018245A1

公开(公告)日：2013-01-17

申请号：US13394997

申请日：2010-09-07

申请人： Paul Chamney ,  Ulrich Moissl ,  Peter Wabel ,  Volker Nier ,  Sebastian Wieskotten

发明人： Paul Chamney ,  Ulrich Moissl ,  Peter Wabel ,  Nestor Velasco ,  Volker Nier ,  Sebastian Wieskotten

IPC分类号： A61B5/00

CPC分类号： G01N33/483 ,  A61B5/0537 ,  A61B5/14542 ,  A61B5/4839 ,  A61B5/7264

摘要： The present invention relates to a method for evaluating a value representing the mass or the concentration of a substance comprised by a tissue or a bodily fluid of a patient, the method including the steps of a) determining a relation between one or more calculated or measured value(s) reflecting the mass or the concentration and a distribution space of the patient or an approximation thereof, and b) assessing whether the relation fulfils a criterion. The present invention further relates to systems and computer programs for performing this method.

摘要翻译： 本发明涉及一种用于评估表示由患者的组织或体液组成的物质的质量或浓度的值的方法，所述方法包括以下步骤：a）确定一个或多个计算或测量的 反映患者的质量或浓度和分布空间的值或其近似值，以及b）评估该关系是否满足标准。 本发明还涉及用于执行该方法的系统和计算机程序。

公开(公告)号：US09186448B2

公开(公告)日：2015-11-17

申请号：US13642636

申请日：2011-04-15

申请人： Paul Chamney ,  Ulrich Moissl ,  Peter Wabel ,  Sebastian Wieskotten

发明人： Paul Chamney ,  Ulrich Moissl ,  Peter Wabel ,  Sebastian Wieskotten

IPC分类号： A61M1/16 ,  A61M1/34 ,  B01D61/32 ,  A61M1/36 ,  A61B5/00 ,  G06F19/00

CPC分类号： A61M1/16 ,  A61B5/4875 ,  A61M1/1613 ,  A61M1/3403 ,  A61M1/3609 ,  A61M2205/33 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/20 ,  G06F19/00 ,  G06F19/34

摘要： The present invention relates to a method for controlling a filtration rate during treatment of a body fluid, e.g., during hemofiltration or dialysis, comprising the steps of defining a target relation, or a development during dialysis thereof, between one or more calculated or measured value(s) reflecting the mass, concentration, or the volume of a substance comprised by a patient's tissue or bodily fluid, and one or more calculated or measured value(s) reflecting a patient's distribution space or an approximation thereof; during dialysis repeatedly calculating or measuring value(s) reflecting the mass, concentration or the volume of the substance and/or reflecting the distribution space or an approximation thereof, and determining the relation therebetween at least once; and controlling the filtration rate of the body fluid treatment device such that the determined relation is or approaches the target relation. It also relates to systems for conducting the method, and related computer-readable storage media.

摘要翻译： 本发明涉及一种控制体液处理过程中过滤速率的方法，例如在血液滤过或透析过程中，包括以下步骤：在一个或多个计算值或测量值之间定义目标关系或其透析期间的发展 反映患者组织或体液包含的物质的质量，浓度或体积以及反映患者分布空间或近似值的一个或多个计算值或测量值; 在透析期间反复计算或测量反映物质的质量，浓度或体积和/或反映分布空间或其近似值的值，并确定其间的关系至少一次; 以及控制体液处理装置的过滤速度，使得确定的关系是或接近目标关系。 它还涉及用于执行该方法的系统以及相关的计算机可读存储介质。

公开(公告)号：US20130331712A1

公开(公告)日：2013-12-12

申请号：US13997583

申请日：2011-12-21

申请人： Ulrich Moissl ,  Paul Chamney ,  Volker Nier ,  Peter Wabel ,  Sebastian Wieskotten

发明人： Ulrich Moissl ,  Paul Chamney ,  Volker Nier ,  Peter Wabel ,  Sebastian Wieskotten

IPC分类号： A61B5/00 ,  A61B5/0205 ,  A61M1/30 ,  A61B5/0295

CPC分类号： A61B5/4848 ,  A61B5/0205 ,  A61B5/0295 ,  A61B5/4836 ,  A61B5/4875 ,  A61B5/7225 ,  A61B5/7278 ,  A61M1/14 ,  A61M1/16 ,  A61M1/1613 ,  A61M1/30 ,  A61M2205/52 ,  G06F19/3481

摘要： The present invention relates to a method for calculating or approximating a value representing the relative blood volume (RBV) at a certain point of time, or a value representing the refilling volume of a patient that may be observed or found during or due to a blood treatment of the patient, the method involving considering one or more calculated or measured value(s) reflecting an overhydration level of the patient or an approximation thereof. It relates further to an apparatus and a device for carrying out the present invention, a blood treatment device, digital storage means, a computer program product, and a computer program.

摘要翻译： 本发明涉及一种用于计算或近似表示在某个时间点的相对血容量（RBV）的值的方法，或表示在血液中或由于血液可能被观察或发现的患者的再充填体积的值 该方法包括考虑反映患者的过度水平的一个或多个计算值或测量值或其近似值。 本发明还涉及用于实施本发明的装置和装置，血液处理装置，数字存储装置，计算机程序产品和计算机程序。

公开(公告)号：US20130204098A1

公开(公告)日：2013-08-08

申请号：US13810771

申请日：2011-07-19

申请人： Paul Chamney ,  Peter Wabel ,  Ulrich Moissl ,  Sebastian Wieskotten

发明人： Paul Chamney ,  Peter Wabel ,  Ulrich Moissl ,  Sebastian Wieskotten

IPC分类号： A61B5/00 ,  A61B5/117 ,  A61B5/04 ,  A61B5/0205 ,  A61B5/1455 ,  A61B5/1468 ,  A61B7/00 ,  A61B5/107 ,  A61B5/145

CPC分类号： A61B5/0205 ,  A61B5/04005 ,  A61B5/0537 ,  A61B5/1072 ,  A61B5/1073 ,  A61B5/1079 ,  A61B5/1172 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1468 ,  A61B5/4836 ,  A61B5/4869 ,  A61B5/6887 ,  A61B5/6891 ,  A61B5/70 ,  A61B7/00 ,  A61G7/075 ,  A61G15/02 ,  A61G15/12 ,  A61G2210/00 ,  A61G2210/20 ,  A61M1/14 ,  A61M1/1611 ,  A61M2230/65

摘要： The subject matter is a patient supporting device for supporting a patient during a medical treatment, in particular a dialysis treatment, and a treatment apparatus with such a patient supporting device, and a corresponding method for controlling and/or regulating a medical treatment device, in particular a dialysis device, using such a patient supporting device.

摘要翻译： 主题是用于在医疗处理，特别是透析治疗中支撑患者的患者支撑装置，以及具有这种患者支撑装置的治疗装置，以及用于控制和/或调节医疗装置的相应方法， 特别是使用这种患者支撑装置的透析装置。

公开(公告)号：US20120238935A1

公开(公告)日：2012-09-20

申请号：US13503139

申请日：2010-10-21

申请人： Paul Chamney ,  Ulrich Moissl ,  Peter Wabel ,  Volker Nier ,  Sebastian Wieskotten

发明人： Paul Chamney ,  Ulrich Moissl ,  Peter Wabel ,  Volker Nier ,  Sebastian Wieskotten

IPC分类号： A61M1/14 ,  B01D61/22 ,  B01D61/32

CPC分类号： A61M1/1603 ,  A61B5/026 ,  A61B5/0261 ,  A61B5/027 ,  A61B5/03 ,  A61B5/1455 ,  A61B5/14557 ,  A61M1/14 ,  A61M1/1601 ,  A61M1/3403 ,  A61M1/3607 ,  A61M1/3609 ,  A61M2205/058 ,  A61M2205/33 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2230/005 ,  A61M2230/20 ,  A61M2230/201 ,  A61M2230/207 ,  A61M2230/65 ,  G05B15/02

摘要： The present invention relates to a method for assessing a patient's sensitivity to fluid removal from the patient's vascular system or to fluid replacement or addition with regard to the patient's hydration state, the method comprising the step of determining a value reflecting the distribution of fluid between at least two distribution spaces of the body of the patient or changes thereof from measured or calculated values, and assessing whether the value fulfils at least one criterion. It also relates to a controller, an apparatus, a device, a digital storage device, a computer program product, and a computer program.

摘要翻译： 本发明涉及一种用于评估患者对患者血管系统的流体去除的敏感性或关于患者的水合状态的流体替换或添加的方法，所述方法包括以下步骤：确定反映在 患者身体的至少两个分配空间或其从测量值或计算值的变化，以及评估该值是否满足至少一个标准。 它还涉及控制器，装置，设备，数字存储设备，计算机程序产品和计算机程序。

公开(公告)号：US10092685B2

公开(公告)日：2018-10-09

申请号：US13991710

申请日：2011-12-09

申请人： Ulrich Moissl ,  Sebastian Wieskotten ,  Paul Chamney ,  Volker Nier ,  Peter Wabel

发明人： Ulrich Moissl ,  Sebastian Wieskotten ,  Paul Chamney ,  Volker Nier ,  Peter Wabel

IPC分类号： B01D21/30 ,  B01D61/00 ,  A61M1/16 ,  G06F19/00 ,  G16H50/50 ,  C02F9/00 ,  B01D65/00 ,  B01J49/00 ,  A61M5/00 ,  A61M1/00

摘要： A method for calculating or estimating or approximating one or more values representing parameters of a patient includes the step of interpolating or extrapolating of at least one later value of a first parameter taking into account at least one earlier value of the first parameter, at least one earlier and at least one later value of a second parameter, and a mathematical relation between the first and the second parameter. An apparatus, a blood treatment device, a digital storage device, a computer program product, and a computer program are also described.

公开(公告)号：US09743843B2

公开(公告)日：2017-08-29

申请号：US13810771

申请日：2011-07-19

申请人： Paul Chamney ,  Peter Wabel ,  Ulrich Moissl ,  Sebastian Wieskotten

发明人： Paul Chamney ,  Peter Wabel ,  Ulrich Moissl ,  Sebastian Wieskotten

IPC分类号： A61B5/053 ,  A61B5/0205 ,  A61B5/1172 ,  A61B5/00 ,  A61G15/02 ,  A61M1/14 ,  A61B5/04 ,  A61B5/107 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1468 ,  A61B7/00 ,  A61M1/16 ,  A61G7/075 ,  A61G15/12

CPC分类号： A61B5/0205 ,  A61B5/04005 ,  A61B5/0537 ,  A61B5/1072 ,  A61B5/1073 ,  A61B5/1079 ,  A61B5/1172 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1468 ,  A61B5/4836 ,  A61B5/4869 ,  A61B5/6887 ,  A61B5/6891 ,  A61B5/70 ,  A61B7/00 ,  A61G7/075 ,  A61G15/02 ,  A61G15/12 ,  A61G2210/00 ,  A61G2210/20 ,  A61M1/14 ,  A61M1/1611 ,  A61M2230/65

摘要： The subject matter is a patient supporting device for supporting a patient during a medical treatment, in particular a dialysis treatment, and a treatment apparatus with such a patient supporting device, and a corresponding method for controlling and/or regulating a medical treatment device, in particular a dialysis device, using such a patient supporting device.

公开(公告)号：US20130081998A1

公开(公告)日：2013-04-04

申请号：US13642636

申请日：2011-04-15

申请人： Paul Chamney ,  Ulrich Moissl ,  Peter Wabel ,  Sebastian Wieskotten

发明人： Paul Chamney ,  Ulrich Moissl ,  Peter Wabel ,  Sebastian Wieskotten

IPC分类号： A61M1/16

CPC分类号： A61M1/16 ,  A61B5/4875 ,  A61M1/1613 ,  A61M1/3403 ,  A61M1/3609 ,  A61M2205/33 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/20 ,  G06F19/00 ,  G06F19/34

摘要： The present invention relates to a method for controlling a filtration rate during treatment of a body fluid, e.g., during hemofiltration or dialysis, comprising the steps of defining a target relation, or a development during dialysis thereof, between one or more calculated or measured value(s) reflecting the mass, concentration, or the volume of a substance comprised by a patient's tissue or bodily fluid, and one or more calculated or measured value(s) reflecting a patient's distribution space or an approximation thereof; during dialysis repeatedly calculating or measuring value(s) reflecting the mass, concentration or the volume of the substance and/or reflecting the distribution space or an approximation thereof, and determining the relation therebetween at least once; and controlling the filtration rate of the body fluid treatment device such that the determined relation is or approaches the target relation. It also relates to systems for conducting the method, and related computer-readable storage media.

摘要翻译： 本发明涉及一种控制体液处理过程中过滤速率的方法，例如在血液滤过或透析过程中，包括以下步骤：在一个或多个计算值或测量值之间定义目标关系或其透析期间的发展 反映患者组织或体液包含的物质的质量，浓度或体积以及反映患者分布空间或近似值的一个或多个计算值或测量值; 在透析期间反复计算或测量反映物质的质量，浓度或体积和/或反映分布空间或其近似值的值，并确定其间的关系至少一次; 以及控制体液处理装置的过滤速度，使得确定的关系是或接近目标关系。 它还涉及用于执行该方法的系统以及相关的计算机可读存储介质。