Human BMP-4 promoter and method for exploring bone-related substance by using the same
    4.
    发明授权
    Human BMP-4 promoter and method for exploring bone-related substance by using the same 失效
    人类BMP-4启动子和通过使用相同物质探索骨相关物质的方法

    公开(公告)号:US06458944B1

    公开(公告)日:2002-10-01

    申请号:US09674460

    申请日:2000-11-30

    IPC分类号: C07H2104

    CPC分类号: C07K14/51

    摘要: The present invention provides a method for exploring low molecular weight compounds which regulate positively or negatively the expression of human BMP-4 with reference to a reporter activity by using 5′ upstream region gene containing the human BMP-4 promoter and an animal cell introduced with a recombinant expression vector that has been connected to an appropriate reporter gene. The low molecular weight compounds and their derivatives obtained by the present method have morphogenetic activity and inhibiting activity for bone and cartilage through the expression of human BMP-4 and are useful as preventive or therapeutic agents for cartilage and bone diseases.

    摘要翻译: 本发明提供一种探索通过使用含有人BMP-4启动子的5'上游区域基因和引入了人BMP-4启动子的动物细胞参照报告基因活性来调节人BMP-4表达的低分子量化合物的方法 已经连接到适当报道基因的重组表达载体。 通过本发明方法获得的低分子化合物及其衍生物通过人BMP-4的表达具有形态发生活性和对骨和软骨的抑制活性,并且可用作软骨和骨疾病的预防或治疗剂。

    Power on reset circuit for semiconductor integrated circuit device
    6.
    发明授权
    Power on reset circuit for semiconductor integrated circuit device 失效
    用于半导体集成电路器件的上电复位电路

    公开(公告)号:US5177375A

    公开(公告)日:1993-01-05

    申请号:US628696

    申请日:1990-12-14

    CPC分类号: G06F1/24

    摘要: A semiconductor integrated circuit device comprising an internal reset circuit generating one shot pulse for resetting an internal circuit upon a power on. In the internal reset circuit, inputted to a two-input NOR gate are an output potential of an inverter inverting a first node coupled to a power supply through a capacitor, and an internal clock signal which level inverts at a predetermined timing after rising to a "H" level upon the power on. Then, the output of the NOR gate is applied to a second node in an internal circuit to be reset. The internal reset circuit outputs one shot pulses synchronizing with the first fall of the internal clock signal after the power on irrespective of a potential change rate of the first node after the power on. The first node is set to more easily attain a "H" level than the second node to be reset to a "L" level at the power on by adjusting characteristics of circuit elements connected to the first node and those of circuit elements connected to the second node. As a result, the second node is set to be without fail at a "L" level requiring no resetting when the inverted potential of the first node has a value allowing a generation of one shot pulses at the NOR gate, thereby preventing malfunction of the internal circuit due to erroneous resetting.

    摘要翻译: 一种半导体集成电路器件,包括内部复位电路,其产生用于在通电时复位内部电路的单次脉冲。 在内部复位电路中,输入到双输入或非门的是逆变器,其通过电容器与耦合到电源的第一节点反相,以及内部时钟信号,该电平在上升至 “H”级上电。 然后,NOR门的输出被施加到要复位的内部电路中的第二节点。 在电源接通之后,内部复位电路输出与内部时钟信号的第一次下降同步的单触发脉冲,而与上电之后第一节点的电位变化率无关。 第一节点被设置为通过调节连接到第一节点的电路元件的特性和连接到第一节点的电路元件的特性,使得能够更容易地达到“H”电平而不是第二节点在上电时被重置为“L”电平 第二个节点。 结果,当第一节点的反相电位具有允许在或非门产生单次脉冲的值时,第二节点被设置为“L”电平而不需要复位,从而防止第 内部电路由于错误的复位而导致。

    Semiconductor memory device including a redundancy circuitry for
repairing a defective memory cell and a method for repairing a
defective memory cell
    7.
    发明授权
    Semiconductor memory device including a redundancy circuitry for repairing a defective memory cell and a method for repairing a defective memory cell 失效
    包括用于修复有缺陷的存储单元的冗余电路的半导体存储器件以及用于修复有缺陷的存储器单元的方法

    公开(公告)号:US5146429A

    公开(公告)日:1992-09-08

    申请号:US617737

    申请日:1990-11-26

    CPC分类号: G11C29/848

    摘要: A semicondcutor memory device includes an array of a plurality of memory cells arranged in a matrix manner, and a row or column decoder responsive to an external address signal for generating a row or column selecting signal. The memory cell array comprises (n+1) rows or columns. The row or column decoder comprises n output nodes. Transmission gates are provided between the decoder output node and row lines or column selecting lines for connecting each output node and each row line or column selecting line. The transmission gates are formed of a pair of CMOS transmission gates, whereby one output node is connected to two adjacent row lines or column selecting lines. This memory device further includes a circuit defining the connection manner of the transmission gate. This defining circuit turns one pair of CMOS transmission gates ON and OFF complementally. When there is a defective memory cell, the decoder output nodes are grouped into a first group including the output node corresponding to the faulty row or column having the defective memory cell, and a second group formed of the remaining output nodes. The defining circuit applies control signals to the CMOS transmission gates so that the ON/OFF states of the CMOS transmission gate pair related to the first group of output nodes and the CMOS transmission gate pair related to the second group of output node differ. The memory device further includes switching devices provided corresponding to each row line or column selecting line, responsive to the control signal from the defining cirucit to be turned on/off. This switching device connects only the faulty row line or the faulty column selecting line to the reference potential fixedly.

    摘要翻译: 半切割器存储器件包括以矩阵方式布置的多个存储器单元的阵列,以及响应于用于产生行或列选择信号的外部地址信号的行或列解码器。 存储单元阵列包括(n + 1)行或列。 行或列解码器包括n个输出节点。 在解码器输出节点和用于连接每个输出节点和每行行或列选择线的行线或列选择线之间提供传输门。 传输门由一对CMOS传输门形成,其中一个输出节点连接到两个相邻的行线或列选择线。 该存储装置还包括限定传输门的连接方式的电路。 该定义电路互补地将一对CMOS传输门ON和OFF。 当存在有缺陷的存储器单元时,解码器输出节点被分组为包括与具有缺陷存储单元的故障行或列相对应的输出节点的第一组,以及由剩余输出节点形成的第二组。 定义电路将控制信号施加到CMOS传输门,使得与第一组输出节点相关的CMOS传输门对的ON / OFF状态和与第二组输出节点相关的CMOS传输门对不同。 存储器件还包括响应于来自定义电路的控制信号而被打开/关闭而对应于每行行或列选择线提供的开关装置。 该开关装置仅将故障行线或故障列选择线固定为参考电位。

    Washing device for parts of body
    8.
    发明授权
    Washing device for parts of body 失效
    身体部位清洗装置

    公开(公告)号:US4551868A

    公开(公告)日:1985-11-12

    申请号:US539751

    申请日:1983-10-06

    IPC分类号: A61M3/02 E03D9/08 A61H35/00

    CPC分类号: E03D9/08

    摘要: In a washing device for parts of body including first cylinder means comprising a first cylinder and a first piston to be operated in the front end direction thereof by introducing pressurized water onto the first cylinder and a second piston to be operated in the front end direction thereof by introducing pressurized water into the second cylinder; pressurized water control means for selectively supplying pressurized water to both of the first and second cylinders, or to any one of them; and pressurized water supply means for supplying pressurized water to the pressurized water control means: the washing device further including sensor means for sensing that any one of the first and second pistons is operated over a predetermined operating position in the front end direction thereof. As one aspect of the invention, the pressurized water control means may be provided with a control member for controlling a supply amount pressurized water and which member is operated based on an input signal of the sensor means to supply a small amount of pressurized water. While, as another aspect of the invention, the pressurized water supply means may comprise pump means the capacity of which is variable to vary the capacity of pump means so as to reduce based on an input signal in the sensor means. The washing device of this invention can spout a weaken fountain for the purpose of bidet-washing with reliability, while it can spout an intensive fountain for the purpose of anus-washing. Also, there is no fear that a person who undergoes the anus or bidet-washing feels unpleasant.

    摘要翻译: 一种用于主体部件的清洗装置,包括第一气缸装置,该第一气缸装置包括第一气缸和通过将加压水引入第一气缸而在其前端方向上操作的第一活塞,以及在其前端方向上操作的第二活塞 通过将加压水引入第二气缸; 加压水控制装置,用于选择性地将加压水供应到第一和第二气缸或它们中的任何一个; 以及用于向加压水控制装置供给加压水的加压供水装置,所述洗涤装置还包括用于感测所述第一活塞和所述第二活塞中的任一个在其前端方向上在预定操作位置上操作的传感器装置。 作为本发明的一个方面,加压水控制装置可以设置有用于控制供给量的加压水的控制构件,并且基于传感器装置的输入信号来操作构件以供应少量的加压水。 而作为本发明的另一方面,加压水供应装置可以包括泵装置,其能力是可变的以改变泵装置的容量,以便基于传感器装置中的输入信号而减小。 本发明的洗涤装置可以以可靠的方式喷出柔软的喷泉,同时可以喷出强化喷泉以进行肛门清洗。 另外,不用担心接触肛门或坐浴盆的人感到不愉快。

    Spread illuminating apparatus
    9.
    发明授权
    Spread illuminating apparatus 有权
    展示照明装置

    公开(公告)号:US08936385B2

    公开(公告)日:2015-01-20

    申请号:US13442148

    申请日:2012-04-09

    IPC分类号: F21V7/04 F21V8/00 G02F1/1335

    摘要: A side-light type spread illuminating apparatus includes a light guiding plate; a light source arranged along a light entering face of the light guiding plate; a double-sided prism sheet arranged at a light emitted face side of the light guiding plate; and an optical member arranged at a back face side facing the light emitted face of the light guiding plate. The optical member includes a light absorption member allowing prevention of reflection of light that has been introduced into the optical member.

    摘要翻译: 侧光型展开照明装置包括导光板; 沿着所述导光板的光进入面布置的光源; 布置在所述导光板的发光面侧的双面棱镜片; 以及光学构件,其布置在面向所述导光板的光发射面的背面侧。 光学构件包括允许防止已经引入光学构件的光的反射的光吸收构件。

    Throttle control heat dissipation device
    10.
    发明授权
    Throttle control heat dissipation device 失效
    节气门控制散热装置

    公开(公告)号:US06892698B2

    公开(公告)日:2005-05-17

    申请号:US10680424

    申请日:2003-10-08

    摘要: A throttle control device includes a throttle body (1). In the throttle body, an intake passage (1a), a first space (24a), and a second space (44) are formed. In the intake passage, a throttle valve (2) is rotatably arranged. The throttle valve is rotated by a motor (4). The motor is accommodated in the first space. The second space communicates with the first space. In addition, the second space is adjacent to the intake passage through the intermediation of a wall portion (20a). This makes it possible for the heat generated in the motor to be effectively dissipated from the first space into the intake passage via the second space and the wall portion.

    摘要翻译: 节气门控制装置包括节气门体(1)。 在节气门体中形成有进气通路(1a),第一空间(24a)和第二空间(44)。 在进气通道中,可旋转地布置节流阀(2)。 节流阀由马达(4)旋转。 电机容纳在第一个空间中。 第二个空间与第一个空间通信。 此外,第二空间通过壁部(20a)的中间与吸气通道相邻。 这使得电动机中产生的热能够经由第二空间和壁部从第一空间有效地散发到进气通道中。