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33 条记录 (耗时 0.018 秒)

    Bicycle rim
    1.
    发明授权
    Bicycle rim 有权
    自行车轮辋

    公开(公告)号：US07377595B1

    公开(公告)日：2008-05-27

    申请号：US11680080

    申请日：2007-02-28

    申请人： Shinpei Okajima ,  Tsutomu Muraoka ,  Takashi Yaegashi

    发明人： Shinpei Okajima ,  Tsutomu Muraoka ,  Takashi Yaegashi

    IPC分类号： B60B21/06 ,  B60B25/00

    CPC分类号： B60B21/062 ,  B60B1/041 ,  B60B1/044 ,  B60B21/023 ,  B60B21/025 ,  B60B21/04 ,  B60B21/08 ,  B60B21/12 ,  B60B2900/311

    摘要： A bicycle rim is provided with an annular metallic rim member and a reinforcing member. The annular metallic rim member has a plurality of spoke attachment arcas with at least one spoke attachment opening in each of the spoke attachment areas and a plurality of intermediate areas disposed between adjacent pairs of the spoke attachment areas. The reinforcing member extends circumferentially about the annular metallic rim member to overlie the spoke attachment areas of the annular metallic rim member. The reinforcing member has a plurality of discrete spoke attachment area reinforcing parts overlying a corresponding one of the spoke attachment areas of the annular metallic rim member. The reinforcing member also has a rim reinforcing part overlying the intermediate areas of the annular metallic rim member and at least partially overlying the discrete spoke attachment area reinforcing parts.

    摘要翻译： 自行车轮圈设置有环形金属轮缘构件和加强构件。 环形金属边缘构件具有多个辐条连接弧，在每个辐条连接区域中具有至少一个辐条连接孔，以及设置在相邻的辐条连接区域对之间的多个中间区域。 加强构件围绕环形金属边缘构件周向延伸以覆盖环形金属边缘构件的轮辐连接区域。 加强构件具有多个分立的轮辐连接区域加强部分，其覆盖环形金属边缘构件的对应的一个轮辐连接区域。 加强构件还具有覆盖环形金属边缘构件的中间区域并且至少部分地覆盖离散的轮辐连接区域增强部分的边缘加强部分。

    Reinforced bicycle rim
    2.
    发明授权
    Reinforced bicycle rim 有权
    强化自行车轮圈

    公开(公告)号：US07578563B2

    公开(公告)日：2009-08-25

    申请号：US11739748

    申请日：2007-04-25

    申请人： Tsutomu Muraoka ,  Takashi Yaegashi ,  Shinpei Okajima

    发明人： Tsutomu Muraoka ,  Takashi Yaegashi ,  Shinpei Okajima

    IPC分类号： B60B21/06 ,  B60B25/00

    CPC分类号： B60B21/062 ,  B60B1/041 ,  B60B1/044 ,  B60B21/023 ,  B60B21/025 ,  B60B21/04 ,  B60B21/08 ,  B60B21/12

    摘要： A bicycle rim is basically provided with an annular metallic rim member and a reinforcing member. The annular metallic rim member includes a plurality of spoke attachment areas with at least one spoke attachment opening in each of the spoke attachment areas. The reinforcing member overlies an exterior surface of the annular metallic rim member. The reinforcing member includes a plurality of spoke attachment sections individually arranged in a circumferential direction to overlie the spoke attachment openings. The spoke attachment sections include a plurality of discrete first reinforcing parts and a plurality of discrete second reinforcing parts. The first reinforcing parts are attached to the spoke attachment areas around the spoke attachment openings. The second reinforcing parts are attached to the spoke attachment areas to overlie the first reinforcing parts, with the second reinforcing parts being larger than the first reinforcing parts.

    摘要翻译： 自行车边缘基本上设置有环形金属边缘构件和加强构件。 环形金属边缘构件包括在每个辐条连接区域中具有至少一个辐条连接开口的多个辐条连接区域。 加强构件覆盖在环形金属边缘构件的外表面上。 加强构件包括沿圆周方向单独布置以覆盖轮辐附接开口的多个轮辐连接部。 轮辐连接部分包括多个离散的第一加强部分和多个离散的第二加强部分。 第一增强部分附接到轮辐附接开口周围的轮辐连接区域。 第二加强部分附接到轮辐附接区域以覆盖第一加强部分，第二加强部分大于第一加强部分。

    Bicycle rim reinforced with a continuously extending resin material
    3.
    发明授权
    Bicycle rim reinforced with a continuously extending resin material 有权
    用连续延伸的树脂材料增强的自行车轮辋

    公开(公告)号：US07464994B2

    公开(公告)日：2008-12-16

    申请号：US11366810

    申请日：2006-03-03

    申请人： Shinpei Okajima ,  Takashi Yaegashi ,  Tsutomu Muraoka

    发明人： Shinpei Okajima ,  Takashi Yaegashi ,  Tsutomu Muraoka

    IPC分类号： B60B21/06 ,  B60B25/00

    CPC分类号： B60B21/062 ,  B60B1/041 ,  B60B1/042 ,  B60B21/025 ,  B60B21/04 ,  B60B21/08 ,  B60B21/12 ,  B60B27/026 ,  B60B2900/311

    摘要： A bicycle rim is provided with an annular metallic rim member and at least one reinforcing resin material. The annular metallic rim member includes an annular tire attachment portion adapted to have a tire mounted thereon, a first annular side wall portion, a second annular side wall portion and an inner annular wall portion connecting the first and second annular side wall portions with a plurality of spoke attachment openings formed in the inner annular wall portion. The at least one reinforcing resin material is attached to the annular metallic rim member such that the reinforcing resin material continuously extends from the first annular side wall portion across the inner annular wall portion to the second annular side wall portions to overlie exterior surface areas of the first and second annular side wall portions and exterior surface areas of the inner annular wall portion around the spoke attachment openings.

    摘要翻译： 自行车轮圈设置有环形金属边缘构件和至少一种增强树脂材料。 环形金属边缘构件包括适于具有安装在其上的轮胎的环形轮胎安装部分，第一环形侧壁部分，第二环形侧壁部分和将第一和第二环形侧壁部分连接多个的内环形壁部分 形成在内环形壁部分中的辐条连接孔。 所述至少一个增强树脂材料附接到所述环形金属边缘构件，使得所述增强树脂材料从所述第一环形侧壁部分连续地延伸穿过所述内环形壁部分到所述第二环形侧壁部分，以覆盖所述第二环形侧壁部分的外表面区域 第一和第二环形侧壁部分和围绕轮辐连接开口的内环形壁部分的外表面区域。

    Bicycle rim
    4.
    发明申请
    Bicycle rim 有权
    自行车轮辋

    公开(公告)号：US20070205653A1

    公开(公告)日：2007-09-06

    申请号：US11366810

    申请日：2006-03-03

    申请人： Shinpei Okajima ,  Takashi Yaegashi ,  Tsutomu Muraoka

    发明人： Shinpei Okajima ,  Takashi Yaegashi ,  Tsutomu Muraoka

    IPC分类号： B60B21/00

    CPC分类号： B60B21/062 ,  B60B1/041 ,  B60B1/042 ,  B60B21/025 ,  B60B21/04 ,  B60B21/08 ,  B60B21/12 ,  B60B27/026 ,  B60B2900/311

    摘要： A bicycle rim is provided with an annular metallic rim member and at least one reinforcing resin material. The annular metallic rim member includes an annular tire attachment portion adapted to have a tire mounted thereon, a first annular side wall portion, a second annular side wall portion and an inner annular wall portion connecting the first and second annular side wall portions with a plurality of spoke attachment openings formed in the inner annular wall portion. The at least one reinforcing resin material is attached to the annular metallic rim member such that the reinforcing resin material continuously extends from the first annular side wall portion across the inner annular wall portion to the second annular side wall portions to overlie exterior surface areas of the first and second annular side wall portions and exterior surface areas of the inner annular wall portion around the spoke attachment openings.

    摘要翻译： 自行车轮圈设置有环形金属边缘构件和至少一种增强树脂材料。 环形金属边缘构件包括适于具有安装在其上的轮胎的环形轮胎安装部分，第一环形侧壁部分，第二环形侧壁部分和将第一和第二环形侧壁部分连接多个的内环形壁部分 形成在内环形壁部分中的辐条连接孔。 所述至少一个增强树脂材料附接到所述环形金属边缘构件，使得所述增强树脂材料从所述第一环形侧壁部分连续地延伸穿过所述内环形壁部分到所述第二环形侧壁部分，以覆盖所述第二环形侧壁部分的外表面区域 第一和第二环形侧壁部分和围绕辐条附接开口的内环形壁部分的外表面区域。

    Bicycle rim
    5.
    发明授权
    Bicycle rim 有权
    自行车轮辋

    公开(公告)号：US07350877B1

    公开(公告)日：2008-04-01

    申请号：US11592325

    申请日：2006-11-03

    申请人： Tsutomu Muraoka ,  Takashi Yaegashi

    发明人： Tsutomu Muraoka ,  Takashi Yaegashi

    IPC分类号： B60B21/06 ,  B60B25/00

    CPC分类号： B60B21/062 ,  B60B1/041 ,  B60B1/044 ,  B60B21/023 ,  B60B21/025 ,  B60B21/04 ,  B60B21/08 ,  B60B21/12

    摘要： A bicycle rim is provided with an annular metallic rim member and reinforcing member. The annular metallic rim member has a plurality of spoke attachment areas with a spoke attachment opening in each of the spoke attachment areas. The reinforcing member extends circumferentially about the annular metallic rim member to overlie the spoke attachment areas of the annular metallic rim member. The reinforcing member has a plurality of spoke attachment sections overlying the spoke attachment areas, respectively, and a plurality of intermediate sections disposed between adjacent pairs of the spoke attachment sections, with the spoke attachment sections being thicker than the intermediate sections.

    摘要翻译： 自行车轮圈设置有环形金属边缘构件和加强构件。 环形金属边缘构件具有多个辐条连接区域，在每个辐条连接区域中具有辐条附接开口。 加强构件围绕环形金属边缘构件周向延伸以覆盖环形金属边缘构件的轮辐连接区域。 加强构件具有分别覆盖轮辐连接区域的多个轮辐连接部分和设置在相邻成对的轮辐连接部分之间的多个中间部分，轮辐连接部分比中间部分厚。

    Process for producing camptothecin
    6.
    发明授权
    Process for producing camptothecin 失效
    喜树碱的制备方法

    公开(公告)号：US06743918B2

    公开(公告)日：2004-06-01

    申请号：US10239113

    申请日：2002-11-25

    申请人： Takashi Yaegashi ,  Takanori Ogawa ,  Seigo Sawada

    发明人： Takashi Yaegashi ,  Takanori Ogawa ,  Seigo Sawada

    IPC分类号： C07D49112

    CPC分类号： C07D491/22 ,  A61K31/475

    摘要： Problem: A large scale production of camptothecin, which is a starting compound of irinotecan hydrochloride and various camptothecin derivatives, at a low cost and with ease. Solution: A process for preparing camptothecin, characterized in that it comprises the following steps (a) and (b); (a) the step to hydrolyze 9-methoxycamptothecin or a natural material containing 9-methoxycamptothecin; (b) the step to convert 9-hydroxycamptothecin obtained in the step (a) into camptothecin by 9-O—perfluoro-lower-alkylsulfonylation or 9-O—phenyltetrazolylation, followed by hydrogenolysis.

    摘要翻译： 问题：大量生产喜树碱，它是伊立替康盐酸盐和各种喜树碱衍生物的起始化合物，成本低，易于使用。溶液：一种制备喜树碱的方法，其特征在于它包括以下步骤（a）和 （b）;（a）水解9-甲氧基喜树碱或含有9-甲氧基喜树碱的天然物质的步骤;（b）将步骤（a）中得到的9-羟基喜树碱通过9-O-全氟低级 - 烷基磺酰化或9-O-苯基四唑化，然后氢解。

    Phenanthroindolizidine compound and NFκB inhibitor containing same as active ingredient
    9.
    发明授权
    Phenanthroindolizidine compound and NFκB inhibitor containing same as active ingredient 有权
    菲并吲哚哩啶化合物和含有与活性成分相同的NF＆kgr B抑制剂

    公开(公告)号：US09174979B2

    公开(公告)日：2015-11-03

    申请号：US13125698

    申请日：2009-10-23

    申请人： Takashi Ikeda ,  Seigo Sawada ,  Takashi Yaegashi ,  Takeshi Matsuzaki ,  Shusuke Hashimoto ,  Ryuta Yamazaki

    发明人： Takashi Ikeda ,  Seigo Sawada ,  Takashi Yaegashi ,  Takeshi Matsuzaki ,  Shusuke Hashimoto ,  Ryuta Yamazaki

    IPC分类号： C07D471/04 ,  A61K31/437 ,  A61P29/00 ,  A61P35/00 ,  C07D491/147

    CPC分类号： C07D471/04 ,  C07D491/147

    摘要： A novel compound having an excellent NFκB inhibitory effect is provided and specifically disclosed is a compound represented by the following formula (1) or a salt thereof:wherein, R1 represents a hydrogen atom, a lower alkyl group, a lower alkyloxy group, or a halogen atom;R2 represents a hydroxyl group, or a lower alkyloxy group;R3 represents a hydrogen atom, a lower alkyl group, or a halogen atom;R4 represents a hydrogen atom or a lower alkyloxy group;R5 represents a hydrogen atom, a lower alkyloxy group, a halogen atom, a hydroxyl group, or a methylenedioxy group formed together with R6 or an isopropylidenedioxy group formed together with R6;R6 represents a hydrogen atom, a lower alkyloxy group, or a methylenedioxy group formed together with R5 or an isopropylidenedioxy group formed together with R5;R7 represents a hydrogen atom or a lower alkyl group; andR8 represents a hydrogen atom, a hydroxyl group, an amino group, or a lower alkylcarbonyloxy group (excluding the case where R1, R3, R4 and R7 are hydrogen atoms, R2 and R8 are hydroxyl groups, and R5 and R6 are methoxy groups).

    摘要翻译： 提供了具有优异的NF＆Kgr B抑制效果的新化合物，具体公开了下式（1）表示的化合物或其盐：其中，R1表示氢原子，低级烷基，低级烷氧基， 或卤素原子; R2表示羟基或低级烷氧基; R3表示氢原子，低级烷基或卤素原子; R4表示氢原子或低级烷氧基; R5表示与R6一起形成的与R6或异丙烯二氧基一起形成的氢原子，低级烷氧基，卤素原子，羟基或亚甲二氧基; R6表示与R5一起形成的氢原子，低级烷氧基或亚甲二氧基，或与R5形成的异丙烯二氧基; R7表示氢原子或低级烷基; 并且R 8表示氢原子，羟基，氨基或低级烷基羰基氧基（R 1，R 3，R 4和R 7为氢原子的情况除外，R 2和R 8为羟基，R 5和R 6为甲氧基 ）。