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1.发明申请NOVEL NUCLEOTIDE AND AMINO ACID SEQUENCES AND METHODS OF USE THEREOF FOR DIAGNOSIS 审中-公开新型核酸和氨基酸序列及其用于诊断的方法公开(公告)号：US20090317808A1
公开(公告)日：2009-12-24
申请号：US12293068
申请日：2007-03-21
CPC分类号： C12Q1/6883 , C12Q1/6886 , C12Q2600/106
摘要： Novel splice variants, amino acid sequences and nucleotide sequences thereof, and methods of using same.
摘要翻译： 新型剪接变体，氨基酸序列及其核苷酸序列及其使用方法。
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2.发明申请NOVEL NUCLEOTIDE AND AMINO ACID SEQUENCES, AND ASSAYS AND METHODS OF USE THEREOF FOR DIAGNOSIS 审中-公开新型核酸和氨基酸序列及其用于诊断的测定及其使用方法公开(公告)号：US20090275021A1
公开(公告)日：2009-11-05
申请号：US12095110
申请日：2006-11-27
申请人： Osnat Sella-Tavor , Sarah Pollock , Lily Bazak , Elena Tsypkin , Shira Wallach , Eve Montia , Shirley Sameah-Greenwald
发明人： Osnat Sella-Tavor , Sarah Pollock , Lily Bazak , Elena Tsypkin , Shira Wallach , Eve Montia , Shirley Sameah-Greenwald
IPC分类号： C12Q1/68 , C12N15/11 , C07K14/00 , C07K16/18 , C12N15/00 , C07H21/04 , C12N5/06 , C12P21/02 , G01N33/53
CPC分类号： C12Q1/6876 , C07K14/47 , C12Q2600/112 , C12Q2600/156 , C12Q2600/158
摘要： Novel splice variants, amino acid sequences and nucleotide sequences thereof, and methods of using same.
摘要翻译： 新型剪接变体，氨基酸序列及其核苷酸序列及其使用方法。
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3.发明申请公开(公告)号：US20090215042A1
公开(公告)日：2009-08-27
申请号：US11913171
申请日：2006-06-08
申请人： Osnat Sella-Tavor , Sarah Pollock , Gad S. Cojocaru , Amit Novik , Lily Bazak , Elena Tsypkin , Shira Wallach , Shirley Sameah-Greenwald
发明人： Osnat Sella-Tavor , Sarah Pollock , Gad S. Cojocaru , Amit Novik , Lily Bazak , Elena Tsypkin , Shira Wallach , Shirley Sameah-Greenwald
CPC分类号： C07K14/47 , A61K38/00 , C07K2319/00 , C12N9/6491 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/142
摘要： Novel splice variants, amino acid sequences and nucleotide sequences thereof, and methods of using same.
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4.发明申请公开(公告)号：US20090176217A1
公开(公告)日：2009-07-09
申请号：US12089051
申请日：2006-10-03
申请人： Osnat Sella-Tavor , Sarah Pollock , Gad S. Cojocaru , Amit Novik , Lily Bazak , Elena Tsypkin , Shira Wallach , Shirley Sameah-Greenwald
发明人： Osnat Sella-Tavor , Sarah Pollock , Gad S. Cojocaru , Amit Novik , Lily Bazak , Elena Tsypkin , Shira Wallach , Shirley Sameah-Greenwald
CPC分类号： G01N33/74 , C07K14/47 , C07K16/2863 , C07K16/40 , G01N33/574 , G01N33/57492 , G01N33/689 , G01N33/6893 , G01N2333/71 , G01N2800/52
摘要： Novel splice variants, amino acid sequences and nucleotide sequences thereof, and methods of using same.
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公开(公告)号：US20090075257A1
公开(公告)日：2009-03-19
申请号：US11831404
申请日：2007-07-31
申请人： Sarah Pollock , Osnat Sella-Tavor , Amit Novik , Elena Tsypkin , Dan Sztybel , Shira Walach
发明人： Sarah Pollock , Osnat Sella-Tavor , Amit Novik , Elena Tsypkin , Dan Sztybel , Shira Walach
CPC分类号： C12Q1/6886 , C12Q2600/156 , C12Q2600/158 , G16B25/00 , G16B40/00
摘要： Novel splice variant nucleic acid and amino acid sequences are provided. The novel splice variants and their nucleic acid sequences may be used for diagnosis of variant-detectable diseases particularly cancerous diseases.
摘要翻译： 提供了新的剪接变体核酸和氨基酸序列。 新颖的剪接变体及其核酸序列可用于诊断可变型可检测疾病，特别是癌性疾病。
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6.发明授权Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of ovarian cancer 有权核苷酸和氨基酸序列，以及其用于诊断卵巢癌的测定和方法公开(公告)号：US07906635B2
公开(公告)日：2011-03-15
申请号：US12354641
申请日：2009-01-15
申请人： Gad S. Cojocaru , Sarah Pollock , Zurit Levine , Alexander Diber , Guy Kol , Amir Toporik , Rotem Sorek , Dvir Dahary , Michal Ayalon-Soffer , Pinchas Akiva , Amit Novik , Yossi Cohen , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Maxim Shklar
发明人： Gad S. Cojocaru , Sarah Pollock , Zurit Levine , Alexander Diber , Guy Kol , Amir Toporik , Rotem Sorek , Dvir Dahary , Michal Ayalon-Soffer , Pinchas Akiva , Amit Novik , Yossi Cohen , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Maxim Shklar
CPC分类号： G01N33/57449 , C12Q1/6886 , C12Q2600/156 , Y10T436/143333
摘要： Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
摘要翻译： 卵巢癌的新型标志物既敏感又准确。 与卵巢正常组织相反，这些标志物特异性地在卵巢癌中过表达和/或差异表达。 这些标记物在患者样本中单独或组合的测量提供了诊断者可以与卵巢癌中可能诊断相关的信息。 本发明的标记物单独或组合显示卵巢癌与非癌状态之间的高度差异检测。
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7.发明授权Diagnostic markers, especially for in vivo imaging and assays and methods of use thereof 失效诊断标记，特别是用于体内成像和测定及其使用方法公开(公告)号：US07741433B2
公开(公告)日：2010-06-22
申请号：US11929570
申请日：2007-10-30
申请人： Sarah Pollock , Anat Cohen-Dayag , Osnat Sella-Tavor , Shirley Sameah-Greenwald , Shira Walach , Lily Bazak
发明人： Sarah Pollock , Anat Cohen-Dayag , Osnat Sella-Tavor , Shirley Sameah-Greenwald , Shira Walach , Lily Bazak
IPC分类号： C07K5/00
CPC分类号： C12Y304/21109 , C12N9/6424 , C12Q1/6886 , C12Q2600/106
摘要： Novel splice variants as diagnostic markers, preferably membrane-bound. The novel variants according to the present invention may optionally be used for diagnosis of Marker-detectable disease as described herein, optionally through immunohistochemistry.
摘要翻译： 新型剪接变体作为诊断标记，优选膜结合。 根据本发明的新型变体可任选地通过免疫组织化学方法用于本文所述的可标记可检测疾病的诊断。
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8.发明授权Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of cardiac disease 失效核苷酸和氨基酸序列，以及其用于诊断心脏病的测定和方法公开(公告)号：US07714100B2
公开(公告)日：2010-05-11
申请号：US11978203
申请日：2007-10-29
申请人： Yossi Cohen , Alexander Diber , Amir Toporik , Sarah Pollock , Zurit Levine , Michal Ayalon-Soffer , Gad S. Cojocaru , Amit Novik , Guy Kol , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Dvir Dahary , Ronen Shemesh
发明人： Yossi Cohen , Alexander Diber , Amir Toporik , Sarah Pollock , Zurit Levine , Michal Ayalon-Soffer , Gad S. Cojocaru , Amit Novik , Guy Kol , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Dvir Dahary , Ronen Shemesh
IPC分类号： A61K38/00
CPC分类号： C07K14/705 , C07H21/04 , C07K16/18 , C07K2317/34 , C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N33/6893 , G01N2800/324 , G01N2800/325 , G01N2800/327
摘要： Novel markers for cardiac disease that are both sensitive and accurate. These markers are differentially and/or specifically expressed in cardiac tissue, as opposed to other types of tissues, optionally and preferably including muscle tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of cardiac disease, including pathology and/or damage, including acute and/or chronic damage. The markers of the present invention, alone or in combination, show a high degree of differential detection between cardiac disease states and non-cardiac disease states.
摘要翻译： 心脏疾病的新型标志物既敏感又准确。 与其他类型的组织相反，这些标记在心脏组织中是有差别地和/或特异性表达的，任选地和优选地包括肌肉组织。 这些标记物在患者样本中单独或组合的测量提供了诊断者可以与心脏病的可能诊断相关的信息，包括病理学和/或损伤，包括急性和/或慢性损伤。 本发明的标记物单独或组合显示心脏疾病状态与非心脏疾病状态之间的高度差异检测。
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9.发明申请Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer 失效新型核苷酸和氨基酸序列，以及其用于诊断肺癌的测定和方法公开(公告)号：US20060046257A1
公开(公告)日：2006-03-02
申请号：US11051720
申请日：2005-01-27
申请人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad Cojocaru , Michal Ayalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh
发明人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad Cojocaru , Michal Ayalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh
IPC分类号： C12Q1/68
CPC分类号： G01N33/57423 , C12Q1/6886 , C12Q2600/112
摘要： Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.
摘要翻译： 肺癌的新型标志物既敏感又准确。 与正常肺组织相反，这些标志物特异性地在肺癌中过度表达。 这些标记物在患者样本中单独或组合的测量提供了诊断者可以与肺癌可能诊断相关的信息。 本发明的标记物单独或组合显示出肺癌和非癌状态之间的高度差异检测。
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10.发明申请公开(公告)号：US20060040278A1
公开(公告)日：2006-02-23
申请号：US11050857
申请日：2005-01-27
申请人： Gad Cojocaru , Sarah Pollock , Zurit Levine , Alexander Diber , Guy Kol , Amir Toporik , Rotem Sorek , Dvir Dahary , Michal Ayalon-Soffer , Pinchas Akiva , Amit Novik , Yossi Cohen , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Maxim Shklar
发明人： Gad Cojocaru , Sarah Pollock , Zurit Levine , Alexander Diber , Guy Kol , Amir Toporik , Rotem Sorek , Dvir Dahary , Michal Ayalon-Soffer , Pinchas Akiva , Amit Novik , Yossi Cohen , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Maxim Shklar
CPC分类号： G01N33/57449 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158
摘要： Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
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