PIGR-1, a member of immunoglobulin gene superfamily
    1.
    发明授权
    PIGR-1, a member of immunoglobulin gene superfamily 失效
    PIGR-1是免疫球蛋白基因超家族的成员

    公开(公告)号:US06232441B1

    公开(公告)日:2001-05-15

    申请号:US09300985

    申请日:1999-04-28

    IPC分类号: C07K14435

    CPC分类号: C07K14/70503 A61K38/00

    摘要: PIGR-1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing PIGR-1 polypeptides and polynucleotides in the design of protocols for the treatment of rheumatoid arthritis (RA), multiple sclerosis (MS), psoriasis, systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD), among others and diagnostic assays for such conditions.

    摘要翻译: 公开了PIGR-1多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还公开了在设计用于治疗类风湿性关节炎(RA),多发性硬化症(MS),牛皮癣,系统性红斑狼疮(SLE)和炎症性肠病(IBD))的方案中使用PIGR-1多肽和多核苷酸的方法,其中 其他和诊断测定这些条件。

    Tumor necrosis factor related receptor, TR6
    8.
    发明授权
    Tumor necrosis factor related receptor, TR6 失效
    肿瘤坏死因子相关受体TR6

    公开(公告)号:US06313269B1

    公开(公告)日:2001-11-06

    申请号:US09333593

    申请日:1999-06-15

    IPC分类号: C07K14715

    摘要: TR6 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing TR6 polypeptides and polynucleotides in the design of protocols for the treatment of chronic and acute inflammation, arthritis, septicemia, autoimmune diseases (e.g. inflammatory bowel disease, psoriasis), transplant rejection, graft vs. host disease, infection, stroke, ischemia, acute respiratory disease syndrome, restenosis, brain injury, AIDS, Bone diseases, cancer, atheroschlerosis, and Alzheimers disease, among others and diagnostic assays for such conditions.

    摘要翻译: 公开了TR6多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还公开了在设计用于治疗慢性和急性炎症,关节炎,败血症,自身免疫性疾病(例如炎性肠病,牛皮癣),移植排斥,移植物抗宿主病,感染等的方案中使用TR6多肽和多核苷酸的方法, 中风,局部缺血,急性呼吸系统疾病综合征,再狭窄,脑损伤,艾滋病,骨病,癌症,动脉粥样硬化,阿尔茨海默病等。

    Lipid platinum complexes and methods of use thereof
    10.
    发明申请
    Lipid platinum complexes and methods of use thereof 审中-公开
    脂质铂络合物及其使用方法

    公开(公告)号:US20070160656A1

    公开(公告)日:2007-07-12

    申请号:US10555495

    申请日:2004-05-03

    CPC分类号: C07F15/0093 A61K9/127

    摘要: This invention provides novel lipid platinum complexes, liposomally encapsulated lipid platinum complexes, pharmaceutical compositions comprising a lipid platinum complex, and methods for treating cancer using a lipid platinum complex. Kits comprising a unit dosage form of a compound or composition of the invention are also provided.

    摘要翻译: 本发明提供新颖的脂质铂络合物,脂质体包封的脂质铂络合物,包含脂质铂络合物的药物组合物,以及使用脂质铂络合物治疗癌症的方法。 还提供了包含本发明化合物或组合物的单位剂型的试剂盒。