OPTICAL SENSING DEVICE FOR SENSING ANALYTES AND RELATED APPARATUS AND METHODS
    1.
    发明申请
    OPTICAL SENSING DEVICE FOR SENSING ANALYTES AND RELATED APPARATUS AND METHODS 审中-公开
    用于感测分析仪的光学感测装置及相关装置及方法

    公开(公告)号:US20140080729A1

    公开(公告)日:2014-03-20

    申请号:US14006430

    申请日:2012-03-16

    IPC分类号: G01N33/543

    摘要: An optical sensing device and associated apparatus are configured for multiplexed detection of specific analytes in fluid samples. The device has a wavelength-tunable grating-coupler configuration in which a grating is disposed on a surface of a waveguide. Different regions of the grating may be functionalized with different receptors, and may form binding-specific sensors and reference sensors. The receptors are exposed to a fluid sample utilizing a fluidic structure mounted to the device. The device utilizes evanescent waves to sense analytes bound to the waveguide surface. The evanescent wave is sensitive to changes in refractive index at (or near) the waveguide surface. Changes in refractive index occur proportionally to the mass of the bound analyte. The apparatus utilizes a tunable light source to implement swept wavelength interrogation while the input beam is held at a fixed coupling angle relative to the waveguide and grating.

    摘要翻译: 光学感测装置和相关联的装置被配置用于多次检测流体样品中的特定分析物。 该器件具有波长可调光栅耦合器配置,其中光栅设置在波导的表面上。 光栅的不同区域可以用不同的受体功能化,并且可以形成结合特异性传感器和参考传感器。 使用安装到该装置的流体结构将受体暴露于流体样品。 该器件利用ev逝波来感测与波导表面结合的分析物。 ev逝波对波导表面(或附近)的折射率变化敏感。 折射率的变化与结合的分析物的质量成比例地发生。 该设备利用可调谐光源实现扫描波长询问,同时输入光束相对于波导和光栅保持固定的耦合角度。

    Cantilever-based MEMS optical scanning apparatus, system and method
    2.
    发明授权
    Cantilever-based MEMS optical scanning apparatus, system and method 有权
    基于悬臂的MEMS光学扫描仪,系统及方法

    公开(公告)号:US08700134B2

    公开(公告)日:2014-04-15

    申请号:US13259791

    申请日:2010-02-26

    IPC分类号: A61B6/00

    摘要: The present invention relates to an optical scanning apparatus and an optical scanning system The optical system includes an optical engine connected to an optical scanning probe The optical scanning probe images a sample at different lateral positions of the sample The optical scanning probe includes a housing having a longitudinal axis extending in a direction towards a sample to be scanned, a first base having a first moveable mirror supported thereon by a first cantilever connecting the first moveable mirror to the first base, a second base having a second moveable mirror supported thereon by a second cantilever connecting the second moveable mirror to the second base, and a support attaching the first and second bases so that the first moveable mirror and the second moveable mirror are disposed along the longitudinal axis apart from each other.

    摘要翻译: 光学扫描装置和光学扫描系统本发明涉及光学扫描装置和光学扫描系统。该光学系统包括连接到光学扫描探针的光学引擎。光学扫描探针对样品的不同侧向位置成像样品。光学扫描探针包括具有 纵向轴线沿着待扫描样品的方向延伸;第一基座,其具有由第一悬臂支撑在其上的第一可移动反射镜,第一悬臂将第一可移动反射镜连接到第一基座;第二基座,其具有由第二可移动反射镜 将第二可移动反射镜连接到第二基座的悬臂,以及附接第一和第二基座的支撑件,使得第一可移动反射镜和第二可移动反射镜沿着彼此分开的纵向轴线设置。

    HIGH DENSITY FARADAY CUP ARRAY OR OTHER OPEN TRENCH STRUCTURES AND METHOD OF MANUFACTURE THEREOF
    5.
    发明申请
    HIGH DENSITY FARADAY CUP ARRAY OR OTHER OPEN TRENCH STRUCTURES AND METHOD OF MANUFACTURE THEREOF 有权
    高密度法兰杯阵列或其他开放式结构及其制造方法

    公开(公告)号:US20110006204A1

    公开(公告)日:2011-01-13

    申请号:US12921525

    申请日:2009-02-24

    CPC分类号: H01J49/025

    摘要: A detector array and method for making the detector array. The detector array includes a substrate including a plurality of trenches formed therein, and a plurality of collectors electrically isolated from each other, formed on the walls of the trenches, and configured to collect charged particles incident on respective ones of the collectors and to output from the collectors signals indicative of charged particle collection. In the detector array, adjacent ones of the plurality of trenches are disposed in a staggered configuration relative to one another. The method forms in a substrate a plurality of trenches across a surface of the substrate such that adjacent ones of the trenches are in a staggered sequence relative to one another, forms in the plurality of trenches a plurality of collectors, and connects a plurality of electrodes respectively to the collectors.

    摘要翻译: 用于制造检测器阵列的检测器阵列和方法。 探测器阵列包括一个衬底,该衬底包括形成在其中的多个沟槽,以及形成在沟槽壁上的彼此电隔离的多个集电极,并且被配置成收集入射在相应集电极上的带电粒子,并从 收集器信号指示带电粒子收集。 在检测器阵列中,多个沟槽中的相邻的沟槽相对于彼此以交错的配置布置。 该方法在衬底中形成穿过衬底的表面的多个沟槽,使得相邻的沟槽相对于彼此处于交错的序列,在多个沟槽中形成多个集电极,并且连接多个电极 分别给收藏家。

    High density faraday cup array or other open trench structures and method of manufacture thereof
    6.
    发明授权
    High density faraday cup array or other open trench structures and method of manufacture thereof 有权
    高密度法拉第杯阵列或其他开槽结构及其制造方法

    公开(公告)号:US08866081B2

    公开(公告)日:2014-10-21

    申请号:US12921525

    申请日:2009-02-24

    IPC分类号: G01T1/00 H01J49/02

    CPC分类号: H01J49/025

    摘要: A detector array and method for making the detector array. The detector array includes a substrate including a plurality of trenches formed therein, and a plurality of collectors electrically isolated from each other, formed on the walls of the trenches, and configured to collect charged particles incident on respective ones of the collectors and to output from the collectors signals indicative of charged particle collection. In the detector array, adjacent ones of the plurality of trenches are disposed in a staggered configuration relative to one another. The method forms in a substrate a plurality of trenches across a surface of the substrate such that adjacent ones of the trenches are in a staggered sequence relative to one another, forms in the plurality of trenches a plurality of collectors, and connects a plurality of electrodes respectively to the collectors.

    摘要翻译: 用于制造检测器阵列的检测器阵列和方法。 探测器阵列包括一个衬底,该衬底包括形成在其中的多个沟槽,以及形成在沟槽壁上的彼此电隔离的多个集电极,并且被配置成收集入射在相应集电极上的带电粒子,并从 收集器信号指示带电粒子收集。 在检测器阵列中,多个沟槽中的相邻的沟槽相对于彼此以交错的配置布置。 该方法在衬底中形成穿过衬底的表面的多个沟槽,使得相邻的沟槽相对于彼此处于交错的序列,在多个沟槽中形成多个集电极,并且连接多个电极 分别给收藏家。

    Faraday cup array integrated with a readout IC and method for manufacture thereof
    7.
    发明授权
    Faraday cup array integrated with a readout IC and method for manufacture thereof 有权
    与读出IC集成的法拉第杯阵列及其制造方法

    公开(公告)号:US08866080B2

    公开(公告)日:2014-10-21

    申请号:US12921508

    申请日:2009-02-27

    摘要: A detector array and method for making the detector array. The array includes a substrate including a plurality of trenches formed therein, and includes a plurality of collectors electrically isolated from each other, formed on the walls of the trenches, and configured to collect charge particles incident on respective ones of the collectors and to output from said collectors signals indicative of charged particle collection. The array includes a plurality of readout circuits disposed on a side of the substrate opposite openings to the collectors. The readout circuits are configured to read charge collection signals from respective ones of the plurality of collectors.

    摘要翻译: 用于制造检测器阵列的检测器阵列和方法。 该阵列包括一个衬底,该衬底包括形成在其中的多个沟槽,并且包括彼此电隔离的多个集电极,形成在沟槽的壁上,并且被配置成收集入射在相应集电极上的电荷粒子,并从 所述收集器信号指示带电粒子收集。 该阵列包括多个读出电路,该读出电路设置在基板的与集电体相对的开口的一侧。 读出电路被配置为从多个收集器中的相应的一个收集器读取电荷收集信号。