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公开(公告)号：US20120283156A1
公开(公告)日：2012-11-08
申请号：US13428257
申请日：2012-03-23
IPC分类号： C10M125/10 , C10L1/188 , C10L1/19 , C10M133/40 , C10M133/48 , C07C57/12 , C10M133/44 , C10M129/70 , C07C69/533 , C07C57/03 , C07C69/58 , C10L1/224 , C10M133/46
CPC分类号： C07D307/60 , C08F20/14 , C08F20/68 , C08F120/04 , C08F120/10 , C08F122/105 , C08F210/14 , C08F2220/1866 , C08F2222/104 , C10L1/1883 , C10L1/1905 , C10L1/224 , C10M107/32 , C10M129/68 , C10M129/72 , C10M133/16 , C10M135/04 , C10M135/06 , C10M145/08 , C10M149/02 , C10M159/20 , C10M2201/02 , C10M2201/062 , C10M2203/1006 , C10M2203/1025 , C10M2205/028 , C10M2205/0285 , C10M2207/123 , C10M2207/282 , C10M2209/04 , C10M2209/1023 , C10M2215/08 , C10M2215/28 , C10M2217/06 , C10M2219/022 , C10M2219/024 , C10M2219/044 , C10M2219/046 , C10N2210/01 , C10N2210/02 , C10N2210/03 , C10N2210/04 , C10N2210/05 , C10N2220/021 , C10N2220/022 , C10N2230/06 , C10N2230/08 , C10N2230/70 , C10N2240/10 , C10N2250/10 , C10N2260/06 , C10N2260/09 , C10N2270/02 , C11C3/00 , C11C3/003 , C11D3/3746 , C08F220/64 , C08F220/10 , C08F220/04
摘要： This invention relates to functionalized monomers which are reacted with an enophilic reagent (e.g., maleic anhydride) to form an enophilic reagent modified functionalized monomer. The enophilic reagent modified functionalized monomer may be further reacted with one or more additional reagents (e.g., oxygen-containing reagents, nitrogen-containing reagents, metals or metal compounds). The invention relates to base oils which may comprise functional base oils. The invention relates to lubricants, functional fluids, fuels, dispersants, detergents and functional compositions (e.g., cleaning solutions, food products, etc.).
摘要翻译： 本发明涉及与亲和试剂（如马来酸酐）反应形成亲核试剂改性官能化单体的官能化单体。 亲核试剂修饰的官能化单体可以进一步与一种或多种另外的试剂（例如含氧试剂，含氮试剂，金属或金属化合物）反应。 本发明涉及可以包含官能基础油的基础油。 本发明涉及润滑剂，功能流体，燃料，分散剂，洗涤剂和功能组合物（例如，清洁溶液，食品等）。
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公开(公告)号：US20120264664A1
公开(公告)日：2012-10-18
申请号：US13428268
申请日：2012-03-23
IPC分类号： C10M145/12 , C10L1/188 , C08F220/04
CPC分类号： C07D307/60 , C08F20/14 , C08F20/68 , C08F120/04 , C08F120/10 , C08F122/105 , C08F210/14 , C08F2220/1866 , C08F2222/104 , C10L1/1883 , C10L1/1905 , C10L1/224 , C10M107/32 , C10M129/68 , C10M129/72 , C10M133/16 , C10M135/04 , C10M135/06 , C10M145/08 , C10M149/02 , C10M159/20 , C10M2201/02 , C10M2201/062 , C10M2203/1006 , C10M2203/1025 , C10M2205/028 , C10M2205/0285 , C10M2207/123 , C10M2207/282 , C10M2209/04 , C10M2209/1023 , C10M2215/08 , C10M2215/28 , C10M2217/06 , C10M2219/022 , C10M2219/024 , C10M2219/044 , C10M2219/046 , C10N2210/01 , C10N2210/02 , C10N2210/03 , C10N2210/04 , C10N2210/05 , C10N2220/021 , C10N2220/022 , C10N2230/06 , C10N2230/08 , C10N2230/70 , C10N2240/10 , C10N2250/10 , C10N2260/06 , C10N2260/09 , C10N2270/02 , C11C3/00 , C11C3/003 , C11D3/3746 , C08F220/64 , C08F220/10 , C08F220/04
摘要： This invention relates to malienated derivatives made from maleic anhydride, functionalized monomers, and one or more additional reagents, e.g., an oxygen-containing reagent (e.g., alcohol, polyol), a nitrogen-containing reagent (e.g., amine, polyamine, aminoalcohol), a metal and/or a metal compound. The invention relates to lubricants, functional fluids, fuels, dispersants, detergents and functional compositions (e.g., cleaning solutions, food compositions, etc.)
摘要翻译： 本发明涉及由马来酸酐，官能化单体和一种或多种另外的试剂（例如含氧试剂（例如醇，多元醇），含氮试剂（例如胺，多胺，氨基醇） ，金属和/或金属化合物。 本发明涉及润滑剂，功能流体，燃料，分散剂，洗涤剂和功能性组合物（例如，清洁溶液，食品组合物等）
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公开(公告)号：US20120277133A1
公开(公告)日：2012-11-01
申请号：US13428458
申请日：2012-03-23
IPC分类号： C07C229/30 , C10L1/00 , C07C57/02 , C10M169/04 , C10L1/188 , C10L1/182 , C10L1/19
CPC分类号： C07D307/60 , C08F20/14 , C08F20/68 , C08F120/04 , C08F120/10 , C08F122/105 , C08F210/14 , C08F2220/1866 , C08F2222/104 , C10L1/1883 , C10L1/1905 , C10L1/224 , C10M107/32 , C10M129/68 , C10M129/72 , C10M133/16 , C10M135/04 , C10M135/06 , C10M145/08 , C10M149/02 , C10M159/20 , C10M2201/02 , C10M2201/062 , C10M2203/1006 , C10M2203/1025 , C10M2205/028 , C10M2205/0285 , C10M2207/123 , C10M2207/282 , C10M2209/04 , C10M2209/1023 , C10M2215/08 , C10M2215/28 , C10M2217/06 , C10M2219/022 , C10M2219/024 , C10M2219/044 , C10M2219/046 , C10N2210/01 , C10N2210/02 , C10N2210/03 , C10N2210/04 , C10N2210/05 , C10N2220/021 , C10N2220/022 , C10N2230/06 , C10N2230/08 , C10N2230/70 , C10N2240/10 , C10N2250/10 , C10N2260/06 , C10N2260/09 , C10N2270/02 , C11C3/00 , C11C3/003 , C11D3/3746 , C08F220/64 , C08F220/10 , C08F220/04
摘要： This invention relates to functionalized polymers derived from functionalized monomers. The functionalized polymer may be reacted with an enophilic reagent (e.g., maleic anhydride) to form an enophilic reagent modified functionalized polymer. The functionalized polymer may be further reacted with one or more additional reagents, e.g., an oxygen-containing reagent (e.g., alcohol, polyol), a nitrogen-containing reagent (e.g., amine, polyamine, aminoalcohol), a metal, a metal compound, or a mixture of two or more thereof. The invention relates to lubricants, functional fluids, fuels, dispersants, detergents and polymer compositions.
摘要翻译： 本发明涉及衍生自官能化单体的官能化聚合物。 官能化聚合物可以与亲和试剂（例如马来酸酐）反应以形成亲和试剂改性的官能化聚合物。 官能化聚合物可以进一步与一种或多种另外的试剂反应，例如含氧试剂（例如醇，多元醇），含氮试剂（例如胺，多胺，氨基醇），金属，金属化合物 ，或其两种或更多种的混合物。 本发明涉及润滑剂，功能流体，燃料，分散剂，洗涤剂和聚合物组合物。
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公开(公告)号：US20120264662A1
公开(公告)日：2012-10-18
申请号：US13428284
申请日：2012-03-23
IPC分类号： C07C69/52 , C10L1/232 , C07C57/02 , C10M169/04 , C07D307/60 , C07C69/34 , C10L1/12 , C10L1/188
CPC分类号： C07D307/60 , C08F20/14 , C08F20/68 , C08F120/04 , C08F120/10 , C08F122/105 , C08F210/14 , C08F2220/1866 , C08F2222/104 , C10L1/1883 , C10L1/1905 , C10L1/224 , C10M107/32 , C10M129/68 , C10M129/72 , C10M133/16 , C10M135/04 , C10M135/06 , C10M145/08 , C10M149/02 , C10M159/20 , C10M2201/02 , C10M2201/062 , C10M2203/1006 , C10M2203/1025 , C10M2205/028 , C10M2205/0285 , C10M2207/123 , C10M2207/282 , C10M2209/04 , C10M2209/1023 , C10M2215/08 , C10M2215/28 , C10M2217/06 , C10M2219/022 , C10M2219/024 , C10M2219/044 , C10M2219/046 , C10N2210/01 , C10N2210/02 , C10N2210/03 , C10N2210/04 , C10N2210/05 , C10N2220/021 , C10N2220/022 , C10N2230/06 , C10N2230/08 , C10N2230/70 , C10N2240/10 , C10N2250/10 , C10N2260/06 , C10N2260/09 , C10N2270/02 , C11C3/00 , C11C3/003 , C11D3/3746 , C08F220/64 , C08F220/10 , C08F220/04
摘要： This invention relates to functionalized monomers. The functionalized monomer may be reacted with an enophilic reagent (e.g., maleic anhydride) to form an enophilic reagent modified functionalized monomer. The invention relates to lubricants, functional fluids, fuels, dispersants, detergents, functional compositions (e.g., food products, cleaners, etc.), and the like.
摘要翻译： 本发明涉及官能化单体。 官能化单体可以与亲和试剂（例如马来酐）反应以形成亲核试剂改性官能化单体。 本发明涉及润滑剂，功能流体，燃料，分散剂，洗涤剂，功能组合物（例如食品，清洁剂等）等。
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公开(公告)号：US20120245063A1
公开(公告)日：2012-09-27
申请号：US13281108
申请日：2011-10-25
IPC分类号： C10M169/04 , C10L1/19 , C08F220/10 , C10L1/00 , C07C57/02 , C07C229/30 , C10L1/188 , C10L1/182
CPC分类号： C07D307/60 , C08F20/14 , C08F20/68 , C08F120/04 , C08F120/10 , C08F122/105 , C08F210/14 , C08F2220/1866 , C08F2222/104 , C10L1/1883 , C10L1/1905 , C10L1/224 , C10M107/32 , C10M129/68 , C10M129/72 , C10M133/16 , C10M135/04 , C10M135/06 , C10M145/08 , C10M149/02 , C10M159/20 , C10M2201/02 , C10M2201/062 , C10M2203/1006 , C10M2203/1025 , C10M2205/028 , C10M2205/0285 , C10M2207/123 , C10M2207/282 , C10M2209/04 , C10M2209/1023 , C10M2215/08 , C10M2215/28 , C10M2217/06 , C10M2219/022 , C10M2219/024 , C10M2219/044 , C10M2219/046 , C10N2210/01 , C10N2210/02 , C10N2210/03 , C10N2210/04 , C10N2210/05 , C10N2220/021 , C10N2220/022 , C10N2230/06 , C10N2230/08 , C10N2230/70 , C10N2240/10 , C10N2250/10 , C10N2260/06 , C10N2260/09 , C10N2270/02 , C11C3/00 , C11C3/003 , C11D3/3746 , C08F220/64 , C08F220/10 , C08F220/04
摘要： This invention relates to a composition, comprising: an unsaturated functionalized monomer of from about 5 to about 30 carbon atoms, which is: (a) polymerized to form a functionalized polymer; (b) copolymerized with a comonomer to form a functionalized copolymer; or (c) reacted with an enophilic reagent to form a polyfunctionalized monomer. The polyfunctionalized monomer may be polymerized to form a polyfunctionalized polymer which may be further reacted with one or more additional reagents. The invention relates to lubricants, functional fluids, fuels, dispersants, detergents and polymeric resins.
摘要翻译： 本发明涉及一种组合物，其包含：约5至约30个碳原子的不饱和官能化单体，其为：（a）聚合形成官能化聚合物; （b）与共聚单体共聚以形成官能化共聚物; 或（c）与亲和试剂反应以形成多官能化单体。 多官能化单体可以聚合以形成多官能化聚合物，其可以进一步与一种或多种另外的试剂反应。 本发明涉及润滑剂，功能流体，燃料，分散剂，洗涤剂和聚合树脂。
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公开(公告)号：US09738618B2
公开(公告)日：2017-08-22
申请号：US13428268
申请日：2012-03-23
IPC分类号： C08F20/14 , C07D307/60 , C08F20/68 , C08F210/14 , C10L1/188 , C10L1/19 , C10L1/224 , C10M129/72 , C10M133/16 , C10M145/08 , C10M149/02 , C10M159/20 , C11C3/00 , C08F120/04 , C08F120/10 , C08F122/10 , C11D3/37 , C10M107/32 , C10M135/04 , C10M135/06
CPC分类号： C07D307/60 , C08F20/14 , C08F20/68 , C08F120/04 , C08F120/10 , C08F122/105 , C08F210/14 , C08F2220/1866 , C08F2222/104 , C10L1/1883 , C10L1/1905 , C10L1/224 , C10M107/32 , C10M129/68 , C10M129/72 , C10M133/16 , C10M135/04 , C10M135/06 , C10M145/08 , C10M149/02 , C10M159/20 , C10M2201/02 , C10M2201/062 , C10M2203/1006 , C10M2203/1025 , C10M2205/028 , C10M2205/0285 , C10M2207/123 , C10M2207/282 , C10M2209/04 , C10M2209/1023 , C10M2215/08 , C10M2215/28 , C10M2217/06 , C10M2219/022 , C10M2219/024 , C10M2219/044 , C10M2219/046 , C10N2210/01 , C10N2210/02 , C10N2210/03 , C10N2210/04 , C10N2210/05 , C10N2220/021 , C10N2220/022 , C10N2230/06 , C10N2230/08 , C10N2230/70 , C10N2240/10 , C10N2250/10 , C10N2260/06 , C10N2260/09 , C10N2270/02 , C11C3/00 , C11C3/003 , C11D3/3746 , C08F220/64 , C08F220/10 , C08F220/04
摘要： This invention relates to malienated derivatives made from maleic anhydride, functionalized monomers, and one or more additional reagents, e.g., an oxygen-containing reagent (e.g., alcohol, polyol), a nitrogen-containing reagent (e.g., amine, polyamine, aminoalcohol), a metal and/or a metal compound. The invention relates to lubricants, functional fluids, fuels, dispersants, detergents and functional compositions (e.g., cleaning solutions, food compositions, etc.)
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7.发明申请BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS 审中-公开用于治疗炎症，心血管和中枢神经疾病的BIARYL PDE4抑制剂公开(公告)号：US20090324569A1
公开(公告)日：2009-12-31
申请号：US12275163
申请日：2008-11-20
申请人： Jasbir Singh , Mark E. Gurney , Alex Burgin , Vincent Sandanayaka , Alexander Kiselyov , Adalie Motta , Gary Schiltz , Georgeta Hategan , Timothy Hagen
发明人： Jasbir Singh , Mark E. Gurney , Alex Burgin , Vincent Sandanayaka , Alexander Kiselyov , Adalie Motta , Gary Schiltz , Georgeta Hategan , Timothy Hagen
IPC分类号： A61K31/44 , C07D401/04 , C07D231/12 , C07D237/14 , C07D277/38 , C07D285/135 , C07D213/72 , C07D403/10 , C07D413/06 , C07D401/06 , A61K31/4427 , A61K31/5377 , A61K31/4439 , A61K31/4412 , A61K31/4164 , A61K31/4245 , A61K31/445 , A61K31/437 , A61K31/415 , A61K31/506 , A61K31/54 , A61K31/122 , A61K31/435 , A61P9/00 , A61P35/00 , A61P11/00
CPC分类号： C07C217/84 , A61K31/136 , A61K31/397 , A61K31/41 , A61K31/426 , A61K31/437 , A61K31/44 , A61K31/4418 , A61K31/4427 , A61K31/5377 , A61K45/06 , C07B2200/05 , C07C65/40 , C07C69/94 , C07C275/32 , C07C275/62 , C07C305/24 , C07C307/10 , C07D205/04 , C07D207/16 , C07D213/38 , C07D213/40 , C07D213/64 , C07D213/65 , C07D213/73 , C07D213/74 , C07D213/75 , C07D213/76 , C07D213/79 , C07D213/81 , C07D213/84 , C07D213/89 , C07D231/12 , C07D233/90 , C07D239/42 , C07D257/04 , C07D275/06 , C07D277/42 , C07D285/12 , C07D285/135 , C07D401/04 , C07D401/06 , C07D403/04 , C07D471/04 , C07D473/18 , C07D473/40
摘要： The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula I: A particular embodiment is
摘要翻译： 本发明涉及含有至少一个其它环的联芳基化合物属。 该化合物是可用于治疗和预防中风，心肌梗塞和心血管炎性疾病和病症的PDE4抑制剂。 该化合物具有通式I：具体实施方案是
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8.发明申请ARYL SULFONAMIDE PERI-SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE 审中-公开ARYL SULFONAMIDE PERI-取代的BICYCLICS FOR OCCLUSIVE ARTERY DISEASE公开(公告)号：US20090075985A1
公开(公告)日：2009-03-19
申请号：US12264053
申请日：2008-11-03
申请人： Jasbir Singh , Mark Gurney , Georgeta Hategan
发明人： Jasbir Singh , Mark Gurney , Georgeta Hategan
IPC分类号： A61K31/4245 , C07D409/14 , C07D409/12 , C07D413/14 , A61K31/4155 , A61P29/00 , A61P9/00 , A61K31/519 , A61K31/366 , A61K31/5415 , A61K31/444 , A61K31/415 , A61K31/365 , A61K31/4418 , A61K31/40 , A61K31/505 , A61K31/4365 , A61K31/445 , A61P25/00 , A61K31/404 , C07D401/02 , C07D209/04 , A61K31/47
CPC分类号： C07D209/08 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/14
摘要： Aryl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula A representative example is:
摘要翻译： 公开了用于治疗或预防前列腺素介导的疾病或病症的芳基磺酰胺，邻位取代的稠合双环化合物。 化合物具有通式A的代表性实例是：
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9.发明申请BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS 有权用于治疗炎症，心脏病和中枢神经疾病的BIARYL PDE4抑制剂公开(公告)号：US20120183522A1
公开(公告)日：2012-07-19
申请号：US13430164
申请日：2012-03-26
申请人： Jasbir Singh , Mark E. Gurney , Alex Burgin , Vincent Sandanayaka , Alexander Kiselyov , Adalie Motta , Gary Schiltz , Georgeta Hategan , Timothy Hagen
发明人： Jasbir Singh , Mark E. Gurney , Alex Burgin , Vincent Sandanayaka , Alexander Kiselyov , Adalie Motta , Gary Schiltz , Georgeta Hategan , Timothy Hagen
IPC分类号： A61K31/4418 , C07D471/04 , A61K31/437 , C07D401/04 , A61K31/4427 , C07D237/14 , A61K31/50 , C07D413/12 , A61K31/501 , C07D413/06 , A61K31/5377 , C07D279/02 , A61K31/54 , A61K31/473 , A61K31/439 , A61K31/445 , A61K31/44 , A61K31/355 , A61K31/122 , A61K38/43 , A61P25/00 , A61P9/10 , A61P9/00 , A61P35/00 , A61P11/06 , A61P11/00 , A61P25/28 , A61P25/14 , A61P19/00 , A61P25/24 , A61P25/22 , A61P13/10 , C07D213/65
CPC分类号： C07C217/84 , A61K31/136 , A61K31/397 , A61K31/41 , A61K31/426 , A61K31/437 , A61K31/44 , A61K31/4418 , A61K31/4427 , A61K31/5377 , A61K45/06 , C07B2200/05 , C07C65/40 , C07C69/94 , C07C275/32 , C07C275/62 , C07C305/24 , C07C307/10 , C07D205/04 , C07D207/16 , C07D213/38 , C07D213/40 , C07D213/64 , C07D213/65 , C07D213/73 , C07D213/74 , C07D213/75 , C07D213/76 , C07D213/79 , C07D213/81 , C07D213/84 , C07D213/89 , C07D231/12 , C07D233/90 , C07D239/42 , C07D257/04 , C07D275/06 , C07D277/42 , C07D285/12 , C07D285/135 , C07D401/04 , C07D401/06 , C07D403/04 , C07D471/04 , C07D473/18 , C07D473/40
摘要： The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula I: A particular embodiment is
摘要翻译： 本发明涉及含有至少一个其它环的联芳基化合物属。 该化合物是可用于治疗和预防中风，心肌梗塞和心血管炎性疾病和病症的PDE4抑制剂。 该化合物具有通式I：具体实施方案是
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10.发明申请Aryl sulfonamide peri-substituted bicyclics for occlusive artery disease 审中-公开用于闭塞性动脉疾病的芳酰磺酰胺四取代双环体公开(公告)号：US20060142348A1
公开(公告)日：2006-06-29
申请号：US11247456
申请日：2005-10-11
申请人： Jasbir Singh , Mark Gurney , Georgeta Hategan
发明人： Jasbir Singh , Mark Gurney , Georgeta Hategan
IPC分类号： C07D513/02 , A61K31/519 , A61K31/43 , A61K31/4188 , A61K31/4162 , A61K31/401 , A61K31/366
CPC分类号： C07D209/08 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/14
摘要： Aryl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula A representative example is:
摘要翻译： 公开了用于治疗或预防前列腺素介导的疾病或病症的芳基磺酰胺，邻位取代的稠合双环化合物。 化合物具有通式A的代表性实例是：
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