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1.发明授权Method for fabricating a polymer stent with break-away links for enhanced stent retenton 有权用于制造具有用于增强支架保持剂的脱离连接的聚合物支架的方法公开(公告)号：US08414638B2
公开(公告)日：2013-04-09
申请号：US12047040
申请日：2008-03-12
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/9522 , A61F2250/0071 , B29C65/08 , B29C65/1606 , B29C65/1612 , B29C65/1645 , B29C65/1664 , B29C65/1667 , B29C65/48 , B29C65/4895 , B29C65/76 , B29C66/1122 , B29C66/53241 , B29C66/612 , B29C66/69 , B29C66/71 , B29C66/73117 , B29C66/73791 , B29C66/8122 , B29C66/83221 , B29C67/0014 , B29C2035/0822 , B29C2035/0827 , B29K2001/00 , B29K2001/12 , B29K2001/14 , B29K2001/18 , B29K2023/00 , B29K2023/083 , B29K2023/086 , B29K2025/00 , B29K2027/06 , B29K2027/08 , B29K2029/00 , B29K2033/20 , B29K2055/02 , B29K2059/00 , B29K2067/043 , B29K2067/046 , B29K2069/00 , B29K2071/00 , B29K2075/00 , B29K2077/00 , B29K2079/08 , B29K2083/00 , B29K2995/006 , B29L2023/007 , B29L2028/00 , B29L2031/605 , B29L2031/7534 , B29L2031/7542 , B29K2905/00 , B29K2067/00 , B29K2033/12 , B29K2033/08 , B29K2031/04 , B29K2027/16 , B29K2025/08 , B29K2025/06 , B29K2023/22 , B29K2023/18 , B29K2023/08 , B29K2009/06 , B29K2003/00
摘要： Polymer stents with break-away links and methods of forming the links for improved stent retention on an expandable member during delivery are disclosed.
摘要翻译： 公开了具有脱离链节的聚合物支架和形成用于在递送期间在可扩张构件上改善支架保持的连接件的方法。
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公开(公告)号：US20090234432A1
公开(公告)日：2009-09-17
申请号：US12047040
申请日：2008-03-12
CPC分类号： A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/9522 , A61F2250/0071 , B29C65/08 , B29C65/1606 , B29C65/1612 , B29C65/1645 , B29C65/1664 , B29C65/1667 , B29C65/48 , B29C65/4895 , B29C65/76 , B29C66/1122 , B29C66/53241 , B29C66/612 , B29C66/69 , B29C66/71 , B29C66/73117 , B29C66/73791 , B29C66/8122 , B29C66/83221 , B29C67/0014 , B29C2035/0822 , B29C2035/0827 , B29K2001/00 , B29K2001/12 , B29K2001/14 , B29K2001/18 , B29K2023/00 , B29K2023/083 , B29K2023/086 , B29K2025/00 , B29K2027/06 , B29K2027/08 , B29K2029/00 , B29K2033/20 , B29K2055/02 , B29K2059/00 , B29K2067/043 , B29K2067/046 , B29K2069/00 , B29K2071/00 , B29K2075/00 , B29K2077/00 , B29K2079/08 , B29K2083/00 , B29K2995/006 , B29L2023/007 , B29L2028/00 , B29L2031/605 , B29L2031/7534 , B29L2031/7542 , B29K2905/00 , B29K2067/00 , B29K2033/12 , B29K2033/08 , B29K2031/04 , B29K2027/16 , B29K2025/08 , B29K2025/06 , B29K2023/22 , B29K2023/18 , B29K2023/08 , B29K2009/06 , B29K2003/00
摘要： Polymer stents with break-away links and methods of forming the links for improved stent retention on an expandable member during delivery are disclosed.
摘要翻译： 公开了具有脱离链节的聚合物支架和形成用于在递送期间在可扩张构件上改善支架保持的连接件的方法。
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3.发明授权Flow regulation valve for controlling inflation rate of a balloon deploying a scaffold 有权流量调节阀，用于控制展开支架的气球的膨胀率公开(公告)号：US09289319B2
公开(公告)日：2016-03-22
申请号：US13471263
申请日：2012-05-14
申请人： Stephen D. Pacetti , Yunbing Wang
发明人： Stephen D. Pacetti , Yunbing Wang
CPC分类号： A61F2/958 , A61M5/16877 , A61M25/10184 , A61M25/10185 , A61M25/104 , A61M39/24 , A61M2039/2413
摘要： An apparatus and method for controlling inflation pressure, pressurization rate, and volumetric flow rate of a balloon during deployment of a stent or scaffold is disclosed.
摘要翻译： 公开了一种用于在展开支架或支架期间控制气囊的充气压力，加压速率和体积流量的装置和方法。
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4.发明申请Controlling Moisture In And Plasticization Of Bioresorbable Polymer For Melt Processing 有权控制用于熔体加工的生物可吸收聚合物的水分和塑化公开(公告)号：US20130041129A1
公开(公告)日：2013-02-14
申请号：US13207656
申请日：2011-08-11
申请人： Bethany Steichen , Stephen D. Pacetti , Manish Gada , Thierry Glauser , Lothar W. Kleiner , Yunbing Wang , James P. Oberhauser , Ni Ding
发明人： Bethany Steichen , Stephen D. Pacetti , Manish Gada , Thierry Glauser , Lothar W. Kleiner , Yunbing Wang , James P. Oberhauser , Ni Ding
CPC分类号： B29C47/0078 , B29B13/06 , B29B13/065 , B29C47/0014 , B29C47/0021 , B29C47/0023 , B29C47/1018 , B29C47/1072 , B29C47/76 , B29C47/92 , B29C2947/922 , B29C2947/92228 , B29C2947/92342 , B29C2947/92695 , B29C2947/92704 , B29C2947/92723 , B29K2995/006
摘要： Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.
摘要翻译： 公开了用于在挤出之前控制可生物降解和生物可再吸收的聚合物树脂的含水量的方法和系统，其允许聚合物树脂熔体增塑并低于上限以降低或防止分子量损失。 进一步公开的方法涉及用二氧化碳和氟利昂进料到挤出机中的聚合物树脂的增塑。
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公开(公告)号：US07998524B2
公开(公告)日：2011-08-16
申请号：US11953657
申请日：2007-12-10
IPC分类号： A61L33/00
CPC分类号： A61F2/82 , A61F2/06 , A61F2210/0004 , A61F2210/0076 , A61F2250/0067 , A61L31/04 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/00 , A61L2420/08 , A61M29/00 , B32B17/06 , B32B27/38 , Y10T428/31511 , C08L67/04
摘要： Methods are disclosed to improved adhesion of polymer coatings over polymer surfaces of stents which include plasma treatment, applying an adhesion promoting layer, surface treatments with solvents, and mechanical roughening techniques.
摘要翻译： 公开了改进聚合物涂层在支架聚合物表面上的附着力的方法，包括等离子体处理，施加粘合促进层，用溶剂进行表面处理和机械粗糙化技术。
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6.发明申请FLOW REGULATION VALVE FOR CONTROLLING INFLATION RATE OF A BALLOON DEPLOYING A SCAFFOLD 有权流量调节阀，用于控制分配给SCAFFOLD的气瓶的充气速率公开(公告)号：US20130304182A1
公开(公告)日：2013-11-14
申请号：US13471263
申请日：2012-05-14
申请人： Stephen D. Pacetti , Yunbing Wang
发明人： Stephen D. Pacetti , Yunbing Wang
CPC分类号： A61F2/958 , A61M5/16877 , A61M25/10184 , A61M25/10185 , A61M25/104 , A61M39/24 , A61M2039/2413
摘要： An apparatus and method for controlling inflation pressure, pressurization rate, and volumetric flow rate of a balloon during deployment of a stent or scaffold is disclosed.
摘要翻译： 公开了一种用于在展开支架或支架期间控制气囊的充气压力，加压速率和体积流量的装置和方法。
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7.发明申请Medical Devices Made From Polymers With End Group Modification For Improved Thermal Stability 审中-公开由聚合物制成的医疗器械，具有改进热稳定性的端基改性公开(公告)号：US20090319036A1
公开(公告)日：2009-12-24
申请号：US12142562
申请日：2008-06-19
申请人： Yunbing Wang , Stephen D. Pacetti
发明人： Yunbing Wang , Stephen D. Pacetti
CPC分类号： A61L31/06 , A61L31/14 , C08L67/04 , C08L101/02
摘要： Implantable medical devices and methods of forming thereof made from polymers with end groups providing improved thermal stability are disclosed. Implantable medical devices made from such polymers including stabilizing agents are additionally disclosed.
摘要翻译： 公开了可植入的医疗装置及其形成方法，其由端基提供改进的热稳定性的聚合物制成。 另外公开了由包括稳定剂的这种聚合物制成的植入式医疗装置。
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公开(公告)号：US09333099B2
公开(公告)日：2016-05-10
申请号：US13436538
申请日：2012-03-30
申请人： Stephen D. Pacetti , Yunbing Wang , Ni Ding
发明人： Stephen D. Pacetti , Yunbing Wang , Ni Ding
IPC分类号： A61F2/82 , C23C8/00 , C23C8/42 , C23C8/80 , C23C8/10 , C23C26/00 , C23C28/04 , C23C28/00 , C23C30/00 , A61L31/02 , A61L31/08 , A61L31/10 , A61L31/14 , A61F2/915
CPC分类号： A61F2/915 , A61F2/82 , A61F2210/0004 , A61F2210/0009 , A61F2240/001 , A61F2250/003 , A61F2310/00041 , A61L31/022 , A61L31/086 , A61L31/088 , A61L31/10 , A61L31/124 , A61L31/148 , A61L2300/416 , A61L2300/606 , A61L2400/18 , B22D21/007 , B22D25/02 , B22D27/00 , B23K26/38 , B23K26/40 , B23K2103/15 , C23C8/00 , C23C8/10 , C23C8/42 , C23C8/80 , C23C26/00 , C23C28/04 , C23C28/30 , C23C30/00
摘要： Stents or scaffolds made from magnesium or magnesium alloys including additives or barrier coatings that modify the corrosion rate of the stent are disclosed. Methods of forming barrier coatings that modify the corrosion rate of the stent are disclosed.
摘要翻译： 公开了由镁或镁合金制成的支架或支架，包括改变支架腐蚀速率的添加剂或阻隔涂层。 公开了形成改变支架腐蚀速率的阻挡涂层的方法。
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9.发明授权Controlling moisture in and plasticization of bioresorbable polymer for melt processing 有权控制生物可吸收聚合物的水分和塑化，用于熔体加工公开(公告)号：US08841412B2
公开(公告)日：2014-09-23
申请号：US13207656
申请日：2011-08-11
申请人： Bethany Steichen , Stephen D. Pacetti , Manish Gada , Thierry Glauser , Lothar W. Kleiner , Yunbing Wang , James P. Oberhauser , Ni Ding
发明人： Bethany Steichen , Stephen D. Pacetti , Manish Gada , Thierry Glauser , Lothar W. Kleiner , Yunbing Wang , James P. Oberhauser , Ni Ding
IPC分类号： C08F6/00
CPC分类号： B29C47/0078 , B29B13/06 , B29B13/065 , B29C47/0014 , B29C47/0021 , B29C47/0023 , B29C47/1018 , B29C47/1072 , B29C47/76 , B29C47/92 , B29C2947/922 , B29C2947/92228 , B29C2947/92342 , B29C2947/92695 , B29C2947/92704 , B29C2947/92723 , B29K2995/006
摘要： Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.
摘要翻译： 公开了用于在挤出之前控制可生物降解和生物可再吸收的聚合物树脂的含水量的方法和系统，其允许聚合物树脂熔体增塑并低于上限以降低或防止分子量损失。 进一步公开的方法涉及用二氧化碳和氟利昂进料到挤出机中的聚合物树脂的增塑。
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公开(公告)号：US20130261735A1
公开(公告)日：2013-10-03
申请号：US13436538
申请日：2012-03-30
申请人： Stephen D. Pacetti , Yunbing Wang , Ni Ding
发明人： Stephen D. Pacetti , Yunbing Wang , Ni Ding
CPC分类号： A61F2/915 , A61F2/82 , A61F2210/0004 , A61F2210/0009 , A61F2240/001 , A61F2250/003 , A61F2310/00041 , A61L31/022 , A61L31/086 , A61L31/088 , A61L31/10 , A61L31/124 , A61L31/148 , A61L2300/416 , A61L2300/606 , A61L2400/18 , B22D21/007 , B22D25/02 , B22D27/00 , B23K26/38 , B23K26/40 , B23K2103/15 , C23C8/00 , C23C8/10 , C23C8/42 , C23C8/80 , C23C26/00 , C23C28/04 , C23C28/30 , C23C30/00
摘要： Stents or scaffolds made from magnesium or magnesium alloys including additives or barrier coatings that modify the corrosion rate of the stent are disclosed. Methods of forming barrier coatings that modify the corrosion rate of the stent are disclosed.
摘要翻译： 公开了由镁或镁合金制成的支架或支架，包括改变支架腐蚀速率的添加剂或阻隔涂层。 公开了形成改变支架腐蚀速率的阻挡涂层的方法。
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