-
公开(公告)号：US07749529B2
公开(公告)日：2010-07-06
申请号：US11053130
申请日：2005-02-08
Applicant: Stephen R. Ash , Janusz Steczko , Gary L. Swanson
Inventor： Stephen R. Ash , Janusz Steczko , Gary L. Swanson
IPC: A61K31/5415 , A61K31/235 , A61K31/19 , A61F2/00
CPC classification number: A01N37/10 , A01N37/04 , A61L29/14 , A61L29/16 , A61L2300/404 , A61L2300/42 , A61M25/0017
Abstract: This invention relates to compositions, methods, devices and kits relating to the infusion of a catheter lock solution into an indwelling catheter. Inventive compositions, methods, devices and kits aid in diminishing the effects of microbial infection in catheters and occlusion of the catheters. A lock solution provided by the invention includes citrate and a paraben. The solution preferably has a density suitable for retention of the solution in a catheter during the lock period. Another lock solution provided by the invention includes citrate, a paraben and a photo-oxidant, such as, for example, methylene blue.
Abstract translation: 本发明涉及将导管锁定溶液输注到留置导管中的组合物，方法，装置和试剂盒。 本发明的组合物，方法，装置和试剂盒有助于减少导管中的微生物感染和导管闭塞的影响。 本发明提供的锁定溶液包括柠檬酸盐和对羟基苯甲酸酯。 溶液优选具有适于在锁定期间将溶液保留在导管中的密度。 本发明提供的另一种锁定溶液包括柠檬酸盐，对羟基苯甲酸酯和光氧化剂，例如亚甲基蓝。
-
2.发明申请公开(公告)号：US20100010086A1
公开(公告)日：2010-01-14
申请号：US12309146
申请日：2007-08-03
Applicant: Stephen R. Ash , Janusz Steczko
Inventor： Stephen R. Ash , Janusz Steczko
CPC classification number: A61L29/14 , A01N37/40 , A61L29/16 , A61L2300/216 , A61L2300/406 , A61L2300/42 , A01N37/36 , A01N37/44 , A01N2300/00
Abstract: The invention relates to compositions that provide antimicrobial therapy for indwelling catheters and as topical disinfectants, and methods, devices and kits relating thereto. In one aspect, the invention relates to the infusion of a catheter lock solution into an indwelling catheter. Use of inventive compositions as catheter lock solutions advantageously aid in diminishing the effects of microbial infection in catheters and occlusion of the catheters. In other aspects, antimicrobial compositions are used to topically sanitize wounds, skin areas and/or other surfaces. An antimicrobial composition provided by the invention includes EDTA, a paraben, and optionally one or both of citrate and a photo-oxidant.
Abstract translation: 本发明涉及提供用于留置导管和局部消毒剂的抗微生物治疗的组合物，以及与其相关的方法，装置和试剂盒。 一方面，本发明涉及将导管锁定溶液输注到留置导管中。 使用本发明的组合物作为导管锁定溶液有利地有助于减少导管中的微生物感染和导管闭塞的影响。 在其他方面，抗微生物组合物用于对伤口，皮肤区域和/或其它表面进行局部消毒。 本发明提供的抗微生物组合物包括EDTA，对羟基苯甲酸酯和任选的一种或两种柠檬酸盐和光氧化剂。
-
公开(公告)号：US20090291944A1
公开(公告)日：2009-11-26
申请号：US12154557
申请日：2008-05-23
Applicant: Stephen R. Ash , Janusz Steczko
Inventor： Stephen R. Ash , Janusz Steczko
IPC: A61K31/5415 , A61K31/045 , A61K31/194
CPC classification number: A01N43/84 , A01N31/02 , A01N37/02 , A01N37/10 , A61L2/0088 , A61L2/18 , A01N25/34 , A01N37/36 , A01N37/40 , A01N2300/00
Abstract: In one aspect, compositions provide antimicrobial therapy as topical disinfectants. Particularly, one aspect relates to an alcohol containing antimicrobial composition that includes at least one paraben, a redox compound and an organic acid at a concentration of from about 1.5 percent to about 10 percent by weight, based on the total weight of the composition. In other aspects, antimicrobial compositions are used to topically sanitize wounds, skin areas and/or to disinfect surgical instruments or other surfaces. Still, in further aspects, methods, devices and kits relating to an antimicrobial composition are provided.
Abstract translation: 在一个方面，组合物提供抗微生物治疗作为局部消毒剂。 特别地，一个方面涉及含醇的抗微生物组合物，其包含至少一种对羟基苯甲酸酯，氧化还原化合物和浓度为组合物总重量的约1.5重量％至约10重量％的有机酸。 在其他方面，抗微生物组合物用于对伤口，皮肤区域进行局部消毒和/或消毒外科器械或其它表面。 然而，在另外的方面，提供了与抗微生物组合物有关的方法，装置和试剂盒。
-
公开(公告)号：US06958049B1
公开(公告)日：2005-10-25
申请号：US09763666
申请日：1999-08-25
Applicant: Stephen R. Ash
Inventor： Stephen R. Ash
CPC classification number: A61L29/14 , A61M25/0017
Abstract: This invention relates to an infusion device for a catheter lock solution, to a method of enhancing the patency of catheters in animals and to a catheter lock solution. The device includes a syringe (34) containing a lock solution comprising a citrate salt. The method for enhancing the patency of catheters includes infusing a lumen (14, 16) of an indwelling catheter (10) with a lock solution comprising a citrate salt. In one aspect of the invention, the catheter lock solution includes a citrate salt and a viscosifying agent. The lock solution is prepared to have sufficient viscosity and density to remain in the lumen for a desired amount of time.
-
公开(公告)号：US06264680B1
公开(公告)日：2001-07-24
申请号：US09235449
申请日：1999-01-22
Applicant: Stephen R. Ash
Inventor： Stephen R. Ash
IPC: A61F700
CPC classification number: A61M1/369 , A61M1/166 , A61M1/26 , A61M1/3437 , A61M1/3458 , A61M1/3493 , A61M1/3621 , A61M2205/12
Abstract: Apparatuses for use in whole body hypothermia include a high-flow hyperthermia circuit coupled to a low-flow dialysis circuit in a manner which reduces tensioning of membranes in the dialyzer of the dialysis circuit. The arrangement thereby allows proper membrane movement to assist in mixing a sorbent suspension circulated on the sorbent side of the dialyzer. Additional dialysis apparatuses include advantageous disposable packs including the dialyzer, sorbent heat exchangers arranged to cooperate with heating elements on base units of the apparatuses, and adaptations for very high flow rates useful in the hyperthermic treatment of cancers.
Abstract translation: 用于全身低体温的装置包括以降低透析回路的透析器中的膜张力的方式耦合到低流量透析回路的高流量热疗回路。 因此，该装置允许适当的膜移动以帮助混合在透析器的吸附剂侧上循环的吸附剂悬浮液。 附加的透析设备包括有利的一次性包装，包括透析器，布置成与装置的基本单元上的加热元件配合的吸附剂热交换器，以及适用于在癌症的高热处理中有用的非常高的流速。
-
Patent Agency Ranking
公开(公告)号：US06042561A
公开(公告)日：2000-03-28
申请号：US956001
申请日：1997-10-22
Applicant: Stephen R. Ash , Elsa M. Janle
Inventor： Stephen R. Ash , Elsa M. Janle
CPC classification number: A61M39/0247
Abstract: A non-intravascular infusion access device and method for long-term continuous infusion of drugs. The infusion access device includes a porous membrane made of a material which is biocompatible for long-term patency inside the body. The porous membrane is connected to a conducting tubing which exits from the body and is connected to a drug infusion system. At the exit site is a cuff of porous material. The cuff serves to anchor the access device in position as the surrounding body tissue grows back around the cuff. There are also two small suture retainers for stabilizing the position of the access device relative until tissue ingrowth occurs in and around the cuff.
Abstract translation: 一种用于长期连续输注药物的非血管内输液装置和方法。 输液进入装置包括由在体内长期通畅生物相容的材料制成的多孔膜。 多孔膜连接到从身体离开并连接到药物输注系统的导管。 在出口处是多孔材料的袖口。 袖带用于在周围的身体组织围绕袖带增长时将访问装置锚定在适当的位置。 还有两个小的缝线保持器，用于稳定进入装置的位置，直到组织向内生长发生在袖带内和周围。
-
公开(公告)号：US5947953A
公开(公告)日：1999-09-07
申请号：US907311
申请日：1997-08-06
Applicant: Stephen R. Ash , Anthony J. Madison , Timothy M. Schweikert
Inventor： Stephen R. Ash , Anthony J. Madison , Timothy M. Schweikert
CPC classification number: A61M25/0021 , A61M2025/0031 , A61M2025/0034 , A61M2025/0037 , A61M2025/004 , A61M25/0043
Abstract: A multiple lumen catheter assembly and methods for inserting the same are provided. The assembly includes a splittable membrane joining a first catheter and a second catheter for allowing the catheters to be at least partially longitudinally split from each other. Each catheter has at least one lumen extending longitudinally through the catheter. One method for inserting the assembly includes making an incision near the area to be catheterized, at least partially splitting the distal end regions of the catheters from each other by splitting apart the splittable membrane, and inserting the distal end regions of the catheters in a juxtaposed relation through the incision and into the area to be catheterized. In another method, the catheters are first tunnelled subcutaneously by pulling the distal end regions of the catheters in the assembly through a tunnel and outwardly from the tunnel near the area to be catheterized, leaving proximal end regions at least partially within the tunnel. An incision is made near the area to be catheterized, the distal end regions of the catheters are at least partially split from each other by splitting the splittable membrane, and the distal end regions of the catheters are inserted in a juxtaposed relation through the incision and into the area to be catheterized.
Abstract translation: 提供了一种多腔导管组件及其插入方法。 该组件包括接合第一导管和第二导管的可分离膜，用于允许导管至少部分地彼此纵向分开。 每个导管具有至少一个沿着导管纵向延伸的内腔。 用于插入组件的一种方法包括在待导管的区域附近形成切口，至少部分地将导管的远端区域彼此分开，通过分开可分离的膜并将导管的远端区域并列插入 通过切口和进入导管区域的关系。 在另一种方法中，导管首先通过穿过隧道拉动组件中的导管的远端区域并从导管区域附近的隧道向外拉动皮下，使得近端区域至少部分地在隧道内。 在待导管的区域附近进行切口，通过分裂可分离的膜，导管的远端区域至少部分地彼此分开，并且导管的远端区域通过切口以并置的关系插入，并且 进入导管区域。
-
公开(公告)号：US5322519A
公开(公告)日：1994-06-21
申请号：US19367
申请日：1993-02-17
Applicant: Stephen R. Ash
Inventor： Stephen R. Ash
Abstract: A foldable peritoneal catheter is provided with a flexible central plenum chamber and flexible fluted wands or rods that extend outwardly from the plenum chamber and serve as liquid transport means for a dialysate fluid or the like. This type of peritoneal catheter is well suited for chronic peritoneal dialysis.
Abstract translation: 可折叠的腹膜导管设置有柔性中央增压室和从充气室向外延伸并用作透析液或类似物的液体输送装置的柔性槽纹棒或杆。 这种类型的腹膜导管非常适合慢性腹膜透析。
-
公开(公告)号：US5277820A
公开(公告)日：1994-01-11
申请号：US832080
申请日：1992-02-06
Applicant: Stephen R. Ash
Inventor： Stephen R. Ash
IPC: A61M1/14 , A61M1/10 , A61M1/16 , A61M1/26 , A61M1/30 , A61M1/34 , B01D61/00 , B01D61/14 , B01D61/24 , B01D61/26 , B01D61/58 , B01D63/16 , B01D65/08
CPC classification number: B01D65/08 , A61M1/1005 , A61M1/1627 , A61M1/1643 , A61M1/1649 , A61M1/1696 , A61M1/267 , A61M1/30 , A61M1/304 , A61M1/308 , A61M1/3417 , A61M1/3427 , A61M1/3431 , A61M1/3475 , A61M1/3493 , B01D61/00 , B01D61/145 , B01D61/243 , B01D61/58 , B01D63/16 , A61M1/1692 , A61M1/26 , A61M1/3472 , A61M2205/12 , A61M2205/7563 , B01D2321/2083 , Y10T436/255
Abstract: Disclosed are preferred devices and methods which provide extracorporeal treatment of blood to effectively and consistently remove toxins therefrom and from patients over extended periods of time.
Abstract translation: 公开了优选的装置和方法，其提供血液的体外治疗以有效且一致地从其中长时间地从患者中去除毒素。
-
10.发明授权
公开(公告)号：US5002054A
公开(公告)日：1991-03-26
申请号：US360362
申请日：1989-06-02
Applicant: Stephen R. Ash , Elsa M. Janle
Inventor： Stephen R. Ash , Elsa M. Janle
IPC: A61B5/00 , A61B10/00 , B01D61/18 , B01D63/02 , G01N33/483 , G01N33/487
CPC classification number: A61B5/14865 , A61B5/14528 , A61B5/14542 , A61B5/1473 , A61B5/686 , B01D61/18 , B01D63/024 , A61B2010/008 , B01D2313/06
Abstract: An implantable filtration and collection device for collecting a filtrate containing a physiological constituent of the body present in an interstitial body space. The device is operable with a negative pressure generating source to withdraw the filtrate from the interstitial body space. The device includes a porous filter made of a material compatible for long-term patency inside the body and adapted to be implanted inside the body in fluid communication with the interstitial space. The pores in the filter are sized not to exceed a predetermined dimension corresponding to the size of the physiological constituent being filtered. A collector in the form of an elongate tube is connected to the filter and and serves to communicate the filtrate externally of the body where it may be withdrawn from the collector by a negative pressure generating source.
Abstract translation: 一种用于收集含有存在于间质体空间中的身体的生理成分的滤液的可植入过滤和收集装置。 该装置可用负压产生源操作，以从间隙体空间抽出滤液。 该装置包括多孔过滤器，其由与体内长期通畅相适应的材料制成，并适于植入体内与间隙空间流体连通。 过滤器中的孔的尺寸不超过对应于被过滤的生理成分的尺寸的预定尺寸。 细长管形式的收集器连接到过滤器，并且用于将滤液从身体外部传递到可以通过负压产生源从收集器抽出的滤液。
-
-
-
-
-
-
-
-
-
Search Results
70
records
(took 0.035 seconds)
