Abstract:
The present invention relates to pyrrolidine sulfonamides, pharmaceutical compositions containing them and their use as urotensin II antagonists.
Abstract:
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
Abstract:
Techniques for reestablishing network address associations upon recovery of a passive optical network (PON) disablement rely on storage address association information. A network node stores address association information in non-volatile memory upon detecting a network disablement. Upon recovery of the PON from the disablement, the network node associates network addresses to clients in accordance with the address association information. The network node may further verify the associations by sending ARP queries for the network addresses to the associated clients. Alternatively, the network nodes may reestablish the address associations by tracking the length of time of the network disablement, and updating address association information in accordance with the length of the disablement.
Abstract:
A fuel cell system (10) is adapted for positioning within a well (W) dug into the ground. The subterranean fuel cell system (10) comprises a capsule (12) for insertion into the well (W) and for containing a fuel cell stack (14), fuel storage tank (16), and a BOP assembly (18). Cathode air enters the system (10) through an inlet pipe (24) and exits via an exhaust pipe (28). The remaining fluid circuitry (e.g., anode fluid circuit, cooling fluid circuit) can be located within the capsule (12) and/or below the ground level (G) whereby external plumbing, and the need for hoses, tubes, and connections, is minimized. The ground can function as a heat sink for absorbing system heat and as an insulator for preventing freezing of reactant and/or cooling water.
Abstract:
A filter assembly includes housing enclosing a replaceable filter element. A support core is provided in the housing, and includes an extension and locking assembly. The element includes a ring of filtration media with a pair of end caps. The first end cap includes a central opening to receive the support core. The extension and locking assembly prevents the cover of the housing from being attached to the housing body without a proper filter element installed. The extension and locking assembly includes a bypass member and a locking member, which are in locking engagement when an element is absent in the housing. The second end cap includes internal protrusions which engage the locking member when the filter element is installed to disengage the bypass member from the support core, and allow the element to be inserted and the cover to be installed.
Abstract:
A filter element removeably located in a housing having a central valve structure. The element has an end cap with a valve actuating portion. The valve actuating portion includes a cylindrical portion and an annular base projecting radially inward from the cylindrical portion. The valve actuating portion includes a plurality of thin, flat keys spaced around the annular base and projecting radially inward from the cylindrical portion and axially outward from the base. The keys engage the valve structure in the housing when the element is installed, and open up a flow passage through the housing.