公开(公告)号：US08071607B2

公开(公告)日：2011-12-06

申请号：US11722484

申请日：2005-12-22

申请人： Thomas Stephen Coulter ,  Steven Taylor ,  Stephen Murfin ,  Valery Thammalaksa ,  Babette Aicher ,  Stefan Jaekel ,  Tanja Reuter

发明人： Thomas Stephen Coulter ,  Steven Taylor ,  Stephen Murfin ,  Valery Thammalaksa ,  Babette Aicher ,  Stefan Jaekel ,  Tanja Reuter

IPC分类号： A01N43/90 ,  A61K31/519

CPC分类号： A61K31/519

摘要： The present invention relates to the use of pyrazolopyrimidine compounds for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof.

摘要翻译： 本发明涉及吡唑并嘧啶化合物用于生产药物组合物用于预防和/或治疗可受到抑制Mnk1和/或Mnk2（Mnk2a或Mnk2b）的激酶活性和/或 其变体。

公开(公告)号：US20100056548A1

公开(公告)日：2010-03-04

申请号：US12296427

申请日：2007-04-10

申请人： Babette Aicher ,  Thomas Stephen Coulter ,  Stefan Jaekel ,  Arndt-René Kelter ,  Stephen Murfin ,  Tanja Reuter ,  Steven Taylor

发明人： Babette Aicher ,  Thomas Stephen Coulter ,  Stefan Jaekel ,  Arndt-René Kelter ,  Stephen Murfin ,  Tanja Reuter ,  Steven Taylor

IPC分类号： A61K31/519 ,  C07D495/04 ,  A61P3/00 ,  A61P35/00 ,  A61P3/10 ,  A61P3/04 ,  A61P9/12 ,  A61P9/00 ,  A61P29/00

CPC分类号： C07D495/04

摘要： The present invention relates to novel pharmaceutical compositions comprising thienopyrimidine compounds. Moreover, the present invention relates to the use of the thienopyrimidine compounds of the invention for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof.

摘要翻译： 本发明涉及包含噻吩并嘧啶化合物的新型药物组合物。 此外，本发明涉及本发明的噻吩并嘧啶化合物用于生产药物组合物用于预防和/或治疗可受到抑制Mnk1和/或Mnk2（Mnk2a）激酶活性的疾病的用途 或Mnk2b）和/或其变体。

公开(公告)号：US20070000329A1

公开(公告)日：2007-01-04

申请号：US11172129

申请日：2005-06-29

申请人： Steven Taylor ,  Nancy Kraft

发明人： Steven Taylor ,  Nancy Kraft

IPC分类号： G01N29/04

CPC分类号： G01N29/2456 ,  B06B1/0651 ,  G01N29/221 ,  G01N29/348

摘要： An ultrasonic transducer having an effective center frequency of about 42 MHz; a bandwidth of greater than 85% at 6 dB; a spherical focus of at least 0.5 inches in water; an F4 lens; a resolution sufficient to be able to detect and separate a 0.005 inch flat-bottomed hole at 0.005 inches below surface; and a beam size of approximately 0.006-0.008 inches measured off a 1½ mm ball in water at the transducer's focal point.

摘要翻译： 具有约42MHz有效中心频率的超声换能器; 6 dB时带宽大于85％; 水中至少0.5英寸的球形焦点; F4镜头; 足以能够检测和分离0.005英寸的低于表面0.005英寸的平底孔的分辨率; 并且在换能器焦点处的水中的1/2英寸球测量的大约0.006-0.008英寸的光束尺寸。

公开(公告)号：US20060276515A1

公开(公告)日：2006-12-07

申请号：US11381015

申请日：2006-05-01

申请人： Charles Cywin ,  Stephane De Lombaert ,  Anne Eldrup ,  Richard Ingraham ,  Fariba Soleymanzadeh ,  Steven Taylor ,  Mario Cardozo

发明人： Charles Cywin ,  Stephane De Lombaert ,  Anne Eldrup ,  Richard Ingraham ,  Fariba Soleymanzadeh ,  Steven Taylor ,  Mario Cardozo

IPC分类号： A61K31/4439 ,  A61K31/4415 ,  A61K31/277 ,  A61K31/165

CPC分类号： C07D213/82 ,  C07D213/56 ,  C07D213/81 ,  C07D215/50 ,  C07D217/26 ,  C07D231/12 ,  C07D231/14 ,  C07D233/90 ,  C07D241/24 ,  C07D295/155 ,  C07D401/04

摘要： Disclosed are compounds active against soluble epoxide hydrolase (sEH), compositions thereof and methods of using and making same.

公开(公告)号：US20050288973A1

公开(公告)日：2005-12-29

申请号：US10875524

申请日：2004-06-24

申请人： Steven Taylor ,  Kevin Krone ,  Victor Lucas ,  Jason Chancellor ,  Michael Neely ,  Mark Gerber ,  Bobby Cude

发明人： Steven Taylor ,  Kevin Krone ,  Victor Lucas ,  Jason Chancellor ,  Michael Neely ,  Mark Gerber ,  Bobby Cude

IPC分类号： G06Q10/00 ,  G06Q50/00

CPC分类号： G06Q50/14 ,  G06Q10/02

摘要： A system and method for changing a travel itinerary include receiving a request to make a change to a first travel itinerary that includes at least one segment, displaying an identification of one or more alternative segments, receiving a user selection of one of the alternative segments, modifying the first itinerary to include a reservation for the selected alternative segment, and releasing the segment of the first itinerary to be replaced by the selected alternative segments. The system and method may also include calculating a fare difference between the one or more alternative segments and the original segment to be replaced.

摘要翻译： 用于改变旅行行程的系统和方法包括接收对包括至少一个段的第一旅行行程进行改变的请求，显示一个或多个替代段的标识，接收替代段之一的用户选择， 修改第一行程以包括所选替代段的预留，以及释放要由所选替代段替换的第一行程的段。 该系统和方法还可以包括计算一个或多个替代段与要替换的原始段之间的车费差值。

公开(公告)号：US6092613A

公开(公告)日：2000-07-25

申请号：US207909

申请日：1998-12-09

申请人： Douglas Caraway ,  John Hayward ,  Malcolm R. Taylor ,  Tom Scott Roberts ,  Steven Taylor ,  Graham R Watson

发明人： Douglas Caraway ,  John Hayward ,  Malcolm R. Taylor ,  Tom Scott Roberts ,  Steven Taylor ,  Graham R Watson

IPC分类号： E21B10/00 ,  E21B10/26 ,  E21B10/54 ,  E21B10/55 ,  E21B10/60 ,  E21B17/10

CPC分类号： E21B10/55 ,  E21B10/003 ,  E21B10/26 ,  E21B10/60 ,  E21B10/602 ,  E21B17/1092

摘要： A rotary drill bit for use in drilling holes in subsurface formations comprises a bit body having a leading face and a gauge region, a number of blades formed on the leading face of the bit and extending outwardly away from the axis of the bit so as to define between the blades a number of fluid channels leading towards the gauge region, a number of cutting elements mounted side-by-side along each blade, and a number of nozzles in the bit body for supplying drilling fluid to the fluid channels for cleaning and cooling the cutting elements. In each of the fluid channels, adjacent the gauge region, is an opening into an enclosed passage which passes internally through the bit body to an outlet which, in use, communicates with the annulus between the drill string and the wall of the borehole being drilled. The gauge region of the drill bit comprises a substantially continuous bearing surface which extends around the whole of the gauge region.

公开(公告)号：USD304219S

公开(公告)日：1989-10-24

申请号：US920800

申请日：1986-10-17

申请人： Steven Taylor

设计人： Steven Taylor

公开(公告)号：US20060263692A1

公开(公告)日：2006-11-23

申请号：US11495520

申请日：2006-07-31

申请人： Kurtis Kelley ,  Steven Taylor

发明人： Kurtis Kelley ,  Steven Taylor

IPC分类号： H01M4/66 ,  B05D5/12 ,  H01M4/68 ,  H01M4/56

CPC分类号： H01M4/366 ,  H01G11/34 ,  H01M4/20 ,  H01M4/73 ,  H01M10/06 ,  Y02E60/126 ,  Y02E60/13 ,  Y02P70/54

摘要： A method for forming a corrosion resistant electrode for a battery includes supplying an electrode for use in the battery and exposing the electrode to an environment including vaporized carbon. At least some of the carbon from the environment may be transferred to the electrode.

公开(公告)号：US20060183387A1

公开(公告)日：2006-08-17

申请号：US11304987

申请日：2005-12-14

申请人： Steven Taylor ,  Mark Longfellow ,  Norman Tracy ,  Robert Henderson ,  Michael Chang ,  Roland Weber

发明人： Steven Taylor ,  Mark Longfellow ,  Norman Tracy ,  Robert Henderson ,  Michael Chang ,  Roland Weber

IPC分类号： B32B5/24

CPC分类号： B32B5/18 ,  B32B5/245 ,  B32B13/045 ,  B32B27/12 ,  B32B27/30 ,  B32B2262/0253 ,  B32B2262/101 ,  B32B2266/0228 ,  B32B2607/00 ,  E04C2/296 ,  E04F13/04 ,  E04F13/047 ,  E04F13/141 ,  E04F13/148 ,  Y10T428/249953 ,  Y10T428/249987 ,  Y10T442/15 ,  Y10T442/159 ,  Y10T442/171 ,  Y10T442/172 ,  Y10T442/176 ,  Y10T442/178 ,  Y10T442/181 ,  Y10T442/183 ,  Y10T442/2861 ,  Y10T442/2992 ,  Y10T442/3325 ,  Y10T442/647

摘要： A composite board for use as backerboard for tile includes outer reinforcement portions and a polystyrene layer disposed between the two outer reinforcement portions, at least one of the outer reinforcement portions being an outer mat fabric reinforcement layer with a mat fabric, and a non-shrinking cement compound saturating and connecting the two outer portions with the polystyrene substrate. A method of installing a composite tile backerboard involves placing the composite board against a fixture protruding from a flat surface, pressing the composite board against the fixture to emboss the features of the fixture on the surface of the composite board, and cutting a hole in the composite board based upon the features of the fixture embossed on the composite board.

摘要翻译： 用作瓦片的背板的复合板包括外部加强部分和设置在两个外部加强部分之间的聚苯乙烯层，至少一个外部加强部分是具有垫子织物的外部垫子织物加强层和不收缩的 水泥化合物饱和并将两个外部部分与聚苯乙烯基板连接。 一种安装复合瓦片背板的方法包括将复合板放置在从平坦表面突出的固定装置上，将复合板压靠在固定装置上，以压印复合板表面上的固定装置的特征，并且在 基于在复合板上压花的夹具的特征的复合板。

公开(公告)号：US07091852B2

公开(公告)日：2006-08-15

申请号：US10802571

申请日：2004-03-17

申请人： Charles Mason ,  Raymond Burkley ,  John Cronin ,  Gordon Taras ,  Jack Boniface ,  Steven Taylor ,  Chet Hom

发明人： Charles Mason ,  Raymond Burkley ,  John Cronin ,  Gordon Taras ,  Jack Boniface ,  Steven Taylor ,  Chet Hom

IPC分类号： G08B1/08 ,  H04M11/04

CPC分类号： H04B7/18595 ,  G01C21/206 ,  G01S5/0027 ,  G01S5/0072 ,  G01S5/0289 ,  G01S13/878 ,  G01S19/17 ,  G08B21/02 ,  H04W4/90 ,  H04W64/00 ,  H04W76/50

摘要： An emergency response personnel automated accountability system, also referred to as a Firefighter Automated Accountability System (FAAS), is provided that supports automatic tracking of and limited communications among first responders including fire, police, emergency medical service, and safety personnel. The FAAS increases situational awareness and safety of first responder personnel by automatically providing position information as well as other sensor information. Components of the FAAS integrate wireless mesh networks with positioning and communication systems to support real-time tracking of and communications with emergency response personnel. The FAAS incident awareness system provides position and time information via Global Positioning System (GPS) and/or other positioning systems, and processed data from sensors to provide enhanced communications, command and control capabilities to the first responders and incident command at the incident scene.

摘要翻译： 提供了一个紧急响应人员自动化问责制度，也称为消防员自动化问责制度（FAAS），支持自动跟踪第一响应者（包括消防，警察，紧急医疗服务和安全人员）的有限通信。 FAAS通过自动提供位置信息以及其他传感器信息，增强了第一反应人员的态势意识和安全性。 FAAS的组件将无线网状网络与定位和通信系统集成，以支持与应急人员的实时跟踪和通信。 FAAS事件感知系统通过全球定位系统（GPS）和/或其他定位系统提供位置和时间信息，以及来自传感器的处理数据，以向事件现场的第一响应者和事件命令提供增强的通信，命令和控制能力。