利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

10 条记录 (耗时 0.036 秒)

    Cantilever sensor and fabrication method thereof
    1.
    发明授权
    Cantilever sensor and fabrication method thereof 失效

    公开(公告)号：US07022540B2

    公开(公告)日：2006-04-04

    申请号：US10448188

    申请日：2003-05-30

    申请人： Tae Song Kim ,  Hyung Joon Kim ,  Jeong Hoon Lee ,  Ji Yoon Kang

    发明人： Tae Song Kim ,  Hyung Joon Kim ,  Jeong Hoon Lee ,  Ji Yoon Kang

    IPC分类号： H01L21/00

    CPC分类号： G01P15/0922 ,  G01P2015/0828

    摘要： In a cantilever sensor and a fabrication thereof, by forming piezoelectric films on the same surface, it is possible to sense various information by an electric measuring method. The cantilever sensor comprises a first silicon nitride film formed onto the top surface of a silicon substrate; a silicon oxide film formed onto the first silicon nitride film; a lower electrode formed onto the silicon oxide film; a first piezoelectric film and a second piezoelectric film formed onto the lower electrode, the second piezoelectric film formed out of contact with the first piezoelectric film; an upper electrode respectively formed onto the first and second piezoelectric films; a protecting film formed onto the silicon oxide film, the lower electrode, the first and second piezoelectric films and the upper electrode; a first and a second openings respectively formed on the protecting film on the upper electrode and the protecting film on the lower electrode; a first and a second contact pads respectively formed at the first and second openings; a T-shaped sensing portion formed at the end of a cantilever; a second silicon nitride film formed on the bottom surface of the silicon substrate.

    Apparatus and method for fabricating micro-capsule
    2.
    发明授权
    Apparatus and method for fabricating micro-capsule 有权
    微胶囊制造装置及方法

    公开(公告)号：US09045747B2

    公开(公告)日：2015-06-02

    申请号：US12154409

    申请日：2008-05-21

    申请人： Choong Kim ,  Ji Yoon Kang ,  Tae Song Kim

    发明人： Choong Kim ,  Ji Yoon Kang ,  Tae Song Kim

    IPC分类号： C12N11/04 ,  C12M1/12 ,  B01F3/08

    CPC分类号： C12N11/04 ,  B01F3/0865 ,  C12M25/16

    摘要： The present invention relates to an apparatus and a method for fabricating a microcapsule, more particularly to an apparatus and a method for fabricating a microcapsule, which enable to encapsulate uniform cell number in a microcapsule through cell distribution, improve cell viability in the microcapsule through fluid exchange, and ensure uniform microcapsule size. The apparatus for fabricating a microcapsule according to the present invention uses a plurality of microchannels which are spatially connected with one another and are designed such that fluid flows through them in a particular direction, and comprises a cell supply unit which supplies a fluid mixture of cells and a cell dropletizing material; and a droplet forming unit in which a dropletization inducing fluid supplied from one of the plurality of microchannels joins with the fluid mixture of the cells and the cell dropletizing material to form a droplet.

    摘要翻译： 本发明涉及一种用于制造微胶囊的装置和方法，更具体地涉及一种用于制造微胶囊的装置和方法，其能够通过细胞分布将微胶囊中的均匀细胞数量包封，通过流体提高微胶囊中的细胞活力 交换，确保微胶囊尺寸均匀。 根据本发明的用于制造微胶囊的装置使用多个彼此空间连接的微通道，并且被设计成使得流体沿着特定方向流过它们，并且包括供应单元的流体混合物的单元供应单元 和细胞液滴化材料; 以及液滴形成单元，其中从所述多个微通道中的一个提供的液滴诱导流体与所述单元和所述单元液滴化材料的流体混合物结合以形成液滴。

    Chip having microchannels and a method for continuous dilution of solution
    3.
    发明申请
    Chip having microchannels and a method for continuous dilution of solution 审中-公开
    具有微通道的芯片和连续稀释溶液的方法

    公开(公告)号：US20080254541A1

    公开(公告)日：2008-10-16

    申请号：US11891228

    申请日：2007-08-09

    申请人： Ji Yoon Kang ,  Choong Kim ,  Kang Sun Lee ,  Sung Shin Ryu ,  Tae Song Kim

    发明人： Ji Yoon Kang ,  Choong Kim ,  Kang Sun Lee ,  Sung Shin Ryu ,  Tae Song Kim

    IPC分类号： G01N31/00 ,  G01N15/06

    CPC分类号： G01N1/38 ,  Y10T436/10

    摘要： A microchannel chip and a dilution method using the same capable of continuously diluting the diverse concentrations of solution by one time fluid injection using the microfluid technology are provided. The microchannels are formed in a plastic chip using the microfluid technology, and a width, a sectional area, or a length of the microchannel is regulated so that the flow rate of a diluted solution (e.g., buffer solution) and a sample (e.g., chemicals or medicament) is controlled. The diluted solution and the specimen are mixed in the mixing channel according to the flow rate, thereby diluting the sample. Such a diluted solution is mixed again with a diluted solution, carrying out the dilution. With the repeated dilution processes, continuously diluted solution is obtained.

    摘要翻译： 提供了使用该微通道芯片的微通道芯片和使用该微流体技术通过一次流体注入连续稀释不同浓度的溶液的稀释方法。 使用微流体技术在塑料芯片中形成微通道，调节微通道的宽度，截面面积或长度，使得稀释溶液（例如缓冲溶液）和样品（例如， 化学品或药物）被控制。 将稀释的溶液和样品根据流速在混合通道中混合，由此稀释样品。 将这种稀释溶液再次与稀释溶液混合，进行稀释。 通过重复稀释过程，获得连续稀释的溶液。

    Apparatus and method for fabricating Micro-Capsule
    4.
    发明申请
    Apparatus and method for fabricating Micro-Capsule 有权
    微胶囊制造装置及方法

    公开(公告)号：US20090269824A1

    公开(公告)日：2009-10-29

    申请号：US12154409

    申请日：2008-05-21

    申请人： Choong Kim ,  Ji Yoon Kang ,  Tae Song Kim

    发明人： Choong Kim ,  Ji Yoon Kang ,  Tae Song Kim

    IPC分类号： C12N11/04

    CPC分类号： C12N11/04 ,  B01F3/0865 ,  C12M25/16

    摘要： The present invention relates to an apparatus and a method for fabricating a microcapsule, more particularly to an apparatus and a method for fabricating a microcapsule, which enable to encapsulate uniform cell number in a microcapsule through cell distribution, improve cell viability in the microcapsule through fluid exchange, and ensure uniform microcapsule size.The apparatus for fabricating a microcapsule according to the present invention uses a plurality of microchannels which are spatially connected with one another and are designed such that fluid flows through them in a particular direction, and comprises a cell supply unit which supplies a fluid mixture of cells and a cell dropletizing material; and a droplet forming unit in which a dropletization inducing fluid supplied from one of the plurality of microchannels joins with the fluid mixture of the cells and the cell dropletizing material to form a droplet.

    摘要翻译： 本发明涉及一种用于制造微胶囊的装置和方法，更具体地涉及一种用于制造微胶囊的装置和方法，其能够通过细胞分布将微胶囊中的均匀细胞数量包封，通过流体提高微胶囊中的细胞活力 交换，确保微胶囊尺寸均匀。 根据本发明的用于制造微胶囊的装置使用多个彼此空间连接的微通道，并且被设计成使得流体沿着特定方向流过它们，并且包括供应单元的流体混合物的单元供应单元 和细胞液滴化材料; 以及液滴形成单元，其中从所述多个微通道中的一个提供的液滴诱导流体与所述单元和所述单元液滴化材料的流体混合物结合以形成液滴。

    METHOD AND DEVICE FOR DNA SEQUENCE ANALYSIS USING MULTIPLE PNA
    8.
    发明申请
    METHOD AND DEVICE FOR DNA SEQUENCE ANALYSIS USING MULTIPLE PNA 审中-公开
    使用多PNA的DNA序列分析的方法和设备

    公开(公告)号：US20120282709A1

    公开(公告)日：2012-11-08

    申请号：US13496059

    申请日：2009-09-14

    申请人： Byung Chul Lee ,  Jin Sik Kim ,  Hyun Joon Shin ,  Sang Youp Lee ,  Ji Yoon Kang

    发明人： Byung Chul Lee ,  Jin Sik Kim ,  Hyun Joon Shin ,  Sang Youp Lee ,  Ji Yoon Kang

    IPC分类号： G01N21/64 ,  G01N21/76 ,  C07K1/26 ,  B82Y5/00 ,  B82Y20/00

    CPC分类号： C12Q1/6869 ,  C12Q2525/107 ,  C12Q2537/161 ,  C12Q2565/631

    摘要： Provided are a DNA sequence analysis method of high precision providing improved optical limits by detecting wavelengths of lights emitted from labels in the state where a DNA is electrically tethered and completely stretch, and a nanodevice chip for automating the method. Also provided are a DNA sequence analysis method capable of removing binding errors through complementarily binding between a plurality of peptide nucleic acids (PNAs) labeled with labels emitting lights of different wavelengths and a target DNA to be sequenced, and resolving the limit in optical spatial resolution.

    摘要翻译： 提供了一种高精度的DNA序列分析方法，其通过检测在DNA被电连接并完全拉伸的状态下从标签发射的光的波长来提供改善的光学限制，以及用于使该方法自动化的纳米设备芯片。 还提供了一种DNA序列分析方法，其能够通过在发射不同波长的光的标记的标记的多个肽核酸（PNA）和待测序的靶DNA之间的互补结合来消除结合错误，并且解决光学空间分辨率的限制 。