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1.发明授权公开(公告)号：US06509410B2
公开(公告)日：2003-01-21
申请号：US09805560
申请日：2001-03-14
IPC分类号： C08K320
CPC分类号： C08G18/0823 , A63B37/0003 , A63B37/0022 , A63B37/0024 , A63B37/12 , C08G18/4063 , C08G18/4236 , C08G18/7831 , C08G18/792 , C09D175/04
摘要： The aqueous coating composition of the present invention can form a high crosslink density owing to the high hydroxyl value, contains a soft urethane structure and alicyclic structure possessed by the water-soluble urethane polyol and the water-dispersible urethane resin, and also contains tough isocyanurate ring structures possessed by the water-dispersible acrylic resin and the hydrophilic polyisocyanate; accordingly, can give a coating film which is high in impact resistance, abrasion resistance, contamination resistance, etc., which has properties equivalent to those possessed by the films produced from organic solvent type coatings, and which has high durability; therefore, is most suitable for coating a golf ball to be hit by a golf club. A golf ball coated with the aqueous coating composition of the present invention is free from cracking or film peeling when hit by a golf club; is low in scratch, abrasion and contamination with grass sap; therefore, can retain gloss and fine appearance.
摘要翻译： 本发明的水性涂料组合物由于羟值高，可形成高交联密度，含有水溶性聚氨酯多元醇和水分散性聚氨酯树脂所具有的软氨基甲酸酯结构和脂环结构，并且还含有韧性异氰脲酸酯 水分散性丙烯酸树脂和亲水性多异氰酸酯所具有的环结构; 因此，可以得到具有与有机溶剂型涂料制造的膜相同的性能，具有高耐久性的耐冲击性，耐磨性，耐污染性等高的涂膜。 因此，最适合于涂覆高尔夫球以被高尔夫球杆撞击。 涂覆有本发明的水性涂料组合物的高尔夫球在被高尔夫球杆撞击时没有破裂或膜剥落; 刮伤，磨损和草液污染少; 因此，可以保持光泽和细腻的外观。
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2.发明申请公开(公告)号：US20070273852A1
公开(公告)日：2007-11-29
申请号：US11662591
申请日：2006-06-30
申请人： Masayoshi Arai
发明人： Masayoshi Arai
CPC分类号： G03F7/70458 , G03F7/7005 , G03F7/70525 , G03F7/70558 , G03F7/70575 , G03F7/70625 , H01S3/10069 , H01S3/1055 , H01S3/1394 , H01S3/225 , H01S2301/08
摘要： An exposure apparatus is equipped with a laser unit that emits a laser beam, a memory that stores a first information which shows a first relation indicating a relation between a linewidth error of a pattern formed on a wafer and a spectral characteristic of the laser beam emitted from the laser unit, and a main controller that controls the spectral width of the laser beam via a laser controller, based on the first information and on information related to a reticle that is to be used. Main controller performs spectral width control of the laser beam so as to suppress linewidth error, based on the first information and on the information related to the reticle that is to be used.
摘要翻译： 曝光装置配备有发射激光束的激光单元，存储第一信息的存储器，该第一信息表示表示晶片上形成的图案的线宽误差与发射的激光束的光谱特性之间的关系的第一关系 以及通过激光控制器控制激光束的光谱宽度的主控制器，基于第一信息和与要使用的掩模版有关的信息。 主控制器根据第一信息和与要使用的掩模版有关的信息，进行激光束的光谱宽度控制，以抑制线宽误差。
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3.发明申请Novel macrolide derivatives havaing effect of potentiating antifungal activity 失效新型大环内酯衍生物具有增强抗真菌活性的作用公开(公告)号：US20050176655A1
公开(公告)日：2005-08-11
申请号：US10472044
申请日：2002-10-29
IPC分类号： A01N43/04 , A61K31/7048 , A61P31/10 , C07H17/08
CPC分类号： C07H17/08 , A61K31/7048
摘要： Macrolide derivatives having enhancing effect for activities of azole antifungal agents, acting at low concentration and within a short time against fungal infection and reducing the frequency of appearance of resistant microorganisms. One such substance is a compound represented by the formula [I]: wherein R1 is Ac, R2 and R3 are Ac, and R4 is Me; when R1 is H, R2 and R3 are Ac, and R4 is Me; when R1 is H, R2 and R3 are Ac, and R4 is H, when R1 Bzl, R2 and R3 are Bzl, and R4 is Me; when R1 is Ac, R2 and R3 are Pr, and R4 is Me; when R1 is Ac, R2 and R3 are Hex, and R4 is Me; when R1 is Ac, R2 and R3 are Bzl, and R4 is Me; when R1 is H, R2 and R3 are Pr, and R4 is Me; when R1 is H, R2 and R3 are Hex, and R4 is Me; when R1 is H, R2 and R3 are Bzl, and R4 is Me; when R1 is H, R2 is H, R3 is Bzl, and R4 is Me; when R1 is H, R2 and R3 are Hex, and R4 is H, or when R1 is H, R2 and R3 are Hex, and R4 is Et.
摘要翻译： 大环内酯衍生物对唑类抗真菌剂的活性具有增强的作用，在低浓度和短时间内对真菌感染起作用，并降低抗性微生物出现的频率。 一种这样的物质是由式[I]表示的化合物：其中R1是Ac，R2和R3是Ac，R4是Me; 当R1为H时，R2和R3为Ac，R4为Me; 当R1为H时，R2和R3为Ac，R4为H时，当R1Bz1，R2和R3为Bz1，R4为Me时; 当R1为Ac时，R2和R3为Pr，R4为Me; 当R1为Ac时，R2和R3为Hex，R4为Me; 当R1为Ac时，R2和R3为Bz1，R4为Me; 当R1为H时，R2和R3为Pr，R4为Me; 当R1为H时，R2和R3为Hex，R4为Me; 当R1为H时，R2和R3为Bz1，R4为Me; 当R1为H时，R2为H，R3为Bz1，R4为Me; 当R1为H时，R2和R3为Hex，R4为H，或当R1为H时，R2和R3为Hex，R4为Et。
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公开(公告)号：US20100206487A1
公开(公告)日：2010-08-19
申请号：US12670321
申请日：2008-07-23
申请人： Masayoshi Arai , Shigetomi Morita
发明人： Masayoshi Arai , Shigetomi Morita
CPC分类号： B29C66/8227 , B23K20/106 , B29C65/08 , B29C66/1122 , B29C66/43 , B29C66/80 , B29C66/81433 , B29C66/8167 , B29C66/8322 , B29C66/9513
摘要： The present invention solves the problem that a connecting portion between a horn and a vibration transmission rod has a tendency to get damaged and the problem associated with the structure in which a chip is attached to an end of the vibration transmission rod, which occur with the known ultrasonic vibration welder. A vibration transmission rod has an end surface serving as a vibration-and-pressure application surface, and a polygonal cross section. The vibration transmission rod is disposed at an end of a horn in such a manner that they vibrate together. The vibration transmission rod and a mass are formed separately. The mass applies pressure to a projection formed at a nodal point of the vibration transmission rod.
摘要翻译： 本发明解决了喇叭和振动传动杆之间的连接部分具有被损坏的倾向的问题，以及与传动杆端部附接有芯片的结构有关的问题， 已知超声波振动焊机。 振动传递杆具有用作振动和压力施加表面的端面和多边形横截面。 振动传递杆以它们一起振动的方式设置在喇叭的一端。 振动传递杆和质量分别形成。 质量对形成在振动传递杆的节点处的突起施加压力。
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公开(公告)号：US20060252930A1
公开(公告)日：2006-11-09
申请号：US10548452
申请日：2003-08-29
申请人： Satoshi Omura , Hiroshi Tomoda , Rokura Masuma , Masayoshi Arai
发明人： Satoshi Omura , Hiroshi Tomoda , Rokura Masuma , Masayoshi Arai
IPC分类号： C07D267/22 , C07K7/60
CPC分类号： C12P17/14 , A61K31/395 , C07D273/00 , C12R1/645
摘要： A microorganism belonging to Beauveria sp. and having ability to produce FKI-1366 substance A and/or FKI-1366 substance B and/or FKI-1366 substance C (Beauveria sp. FKI-1366 FERM BP-08459) is cultured in a medium, accumulating FKI-1366 substance A and/or FKI-1366 substance B and/or FKI-1366 substance C in the culture liquid and isolating FKI-1366 substance A and/or FKI-1366 substance B and/or FKI-1366 substance C from the cultured mass. Since the thus obtained FKI-1366 substance A and/or FKI-1366 substance B and/or FKI-1366 substance C or composition thereof have activity to enhance azole antifungal agent, the substance has an action against various fungal infections such as deep-seated mycosis and other fungal infections in the low concentration within short term. Consequently, the substance is useful for reducing frequency of appearance of resistant microorganisms and overcoming resistance, and is expected as a medicament.
摘要翻译： 属于白僵菌的微生物 并且在培养基中培养产生FKI-1366物质A和/或FKI-1366物质B和/或FKI-1366物质C（白僵菌FKI-1366FERM BP-08459）的能力，将FKI-1366物质A 和/或FKI-1366物质B和/或FKI-1366物质C，并从培养物质中分离FKI-1366物质A和/或FKI-1366物质B和/或FKI-1366物质C。 由于如此获得的FKI-1366物质A和/或FKI-1366物质B和/或FKI-1366物质C或其组合物具有增强唑类抗真菌剂的活性，所以该物质具有针对各种真菌感染的作用，例如深层 短期内低浓度的真菌病和其他真菌感染。 因此，该物质可用于降低抗性微生物的出现频率并克服抗性，并且预期作为药物。
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公开(公告)号：US09371301B2
公开(公告)日：2016-06-21
申请号：US13696425
申请日：2011-05-06
IPC分类号： C07D307/36 , C07D333/06 , A61K31/341 , A61K31/381 , A61K45/06 , C07D333/08
CPC分类号： C07D307/36 , A61K31/341 , A61K31/381 , A61K45/06 , C07D333/08 , A61K2300/00
摘要： A compound represented by the general formula (C): (wherein R101 represents a substituted or unsubstituted aromatic heterocyclic group, R102, R103, R104 and R105 may be the same or different, and each represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, or a haloalkyl group having 1 to 3 carbon atoms, and R106 represents a hydrogen atom, or a saturated or unsaturated hydrocarbon group which is a straight or branched chain having 1 to 12 carbon atoms, but excluded is the case where R101 is a 3-furyl group, R102, R103, R104 and R105 are all methyl groups, and R106 is a methyl group, a 4-methyl-3-pentenyl group or a 4,8-dimethyl-3,7-nonadienyl group); or a pharmaceutically acceptable salt thereof has selective inhibitory activity on hypoxic cell growth in a broad range of the concentration and therefore is useful as an active ingredient of a medicament for cancer prevention or treatment.
摘要翻译： 由通式（C）表示的化合物：（其中R 101表示取代或未取代的芳族杂环基，R 102，R 103，R 104和R 105可以相同或不同，表示氢原子，卤素原子，烷基 具有1至3个碳原子的烷基或具有1至3个碳原子的卤代烷基，R 10 6表示氢原子，或具有1至12个碳原子的直链或支链的饱和或不饱和烃基，但不包括 R 101为3-呋喃基的情况，R102，R103，R104，R105均为甲基，R106为甲基，4-甲基-3-戊烯基或4,8-二甲基-3,7 - 壬二烯基）; 或其药学上可接受的盐在宽范围的浓度下对缺氧细胞生长具有选择性抑制活性，因此可用作用于癌症预防或治疗的药物的活性成分。
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公开(公告)号：US07931706B2
公开(公告)日：2011-04-26
申请号：US11902247
申请日：2007-09-20
申请人： Masayoshi Arai , Tatsuro Watanabe , Akira Saito , Sachio Nakazaki , Toshihisa Maruta , Hiroyuki Takano
发明人： Masayoshi Arai , Tatsuro Watanabe , Akira Saito , Sachio Nakazaki , Toshihisa Maruta , Hiroyuki Takano
IPC分类号： C10L5/00
CPC分类号： C10L5/46 , F23G2206/201 , F23G2900/50208 , Y02E20/363 , Y02E50/10 , Y02E50/30
摘要： A cement kiln from which its brick lining has been removed, or a rotary dryer for cement production is used as a fermentation treatment apparatus 202 for converting waste matter into compost. The waste matter to be subjected to the fermentation treatment includes city waste contained in garbage bags, and its fermentation treatment is carried out by introducing the waste matter directly into the aforesaid cement kiln or the aforesaid rotary dryer for cement production without tearing the aforesaid garbage bags.
摘要翻译： 作为用于将废物转化为堆肥的发酵处理装置202，使用从其排除砖衬的水泥窑或用于水泥生产的旋转干燥器。 要进行发酵处理的废物包括垃圾袋中所含的城市废物，其发酵处理是通过将废物直接引入上述水泥窑或上述用于水泥生产的旋转干燥器中进行的，而不会撕裂上述垃圾袋 。
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公开(公告)号：US07285141B2
公开(公告)日：2007-10-23
申请号：US10101541
申请日：2002-03-20
申请人： Masayoshi Arai , Tatsuro Watanabe , Akira Saito , Sachio Nakazaki , Toshihisa Maruta , Hiroyuki Takano
发明人： Masayoshi Arai , Tatsuro Watanabe , Akira Saito , Sachio Nakazaki , Toshihisa Maruta , Hiroyuki Takano
CPC分类号： C10L5/46 , F23G2206/201 , F23G2900/50208 , Y02E20/363 , Y02E50/10 , Y02E50/30
摘要： A cement kiln from which its brick lining has been removed, or a rotary dryer for cement production is used as a fermentation treatment apparatus 202 for converting waste matter into compost. The waste matter to be subjected to the fermentation treatment includes city waste contained in garbage bags, and its fermentation treatment is carried out by introducing the waste matter directly into the aforesaid cement kiln or the aforesaid rotary dryer for cement production without tearing the aforesaid garbage bags.
摘要翻译： 作为用于将废物转化为堆肥的发酵处理装置202，使用从其排除砖衬的水泥窑或用于水泥生产的旋转干燥器。 要进行发酵处理的废物包括垃圾袋中所含的城市废物，其发酵处理是通过将废物直接引入上述水泥窑或上述用于水泥生产的旋转干燥器中进行的，而不会撕裂上述垃圾袋 。
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公开(公告)号：US08791263B2
公开(公告)日：2014-07-29
申请号：US13823265
申请日：2011-09-16
IPC分类号： C07D405/04 , C07D217/02 , A61K45/00 , A61K31/4725 , A61P43/00 , A61P35/00 , C07D407/10 , C07F7/18 , A61K45/06
CPC分类号： C07D407/10 , A61K31/4725 , A61K45/06 , C07D405/04 , C07F7/1804
摘要： A compound represented by the general formula (M): (wherein R1 represents a substituted or unsubstituted aromatic heterocyclic group, R2 represents a hydrogen atom, a substituted or unsubstituted alkyl group having 1 to 3 carbon atoms, OR3, N(R3)2, C(═O)OR3 or C(═O)N(R3)2, R3 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, or an acyl group having 1 to 4 carbon atoms, R4 represents a hydrogen atom, an oxygen atom or OR5, and R5 represents a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, or an acyl group having 1 to 3 carbon atoms); or a pharmaceutically acceptable salt thereof is a cortistatin A analog which is useful as an active ingredient of medicaments for cancer prevention or treatment in that the analog can be mass-produced by chemical synthesis due to its simple chemical structure and retains the same biological activities as those of cortistatin A.
摘要翻译： 由通式（M）表示的化合物：其中，R1表示取代或未取代的芳香族杂环基，R2表示氢原子，取代或未取代的碳原子数1〜3的烷基，OR3，N（R3）2， C（= O）OR 3或C（= O）N（R3）2，R3表示氢原子，碳原子数1〜4的烷基或碳原子数1〜4的酰基，R4表示氢原子 ，氧原子或OR 5，R5表示氢原子，碳原子数1〜3的烷基或碳原子数1〜3的酰基）。 或其药学上可接受的盐是可用作癌症预防或治疗药物的活性成分的皮质激素A类似物，因为类似物可以通过化学合成由于其简单的化学结构而大规模生产，并保持与 皮质激素A.
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公开(公告)号：US20130065937A1
公开(公告)日：2013-03-14
申请号：US13696425
申请日：2011-05-06
IPC分类号： C07D333/08 , A61P35/00 , A61K31/341 , A61K31/381 , C07D307/36
CPC分类号： C07D307/36 , A61K31/341 , A61K31/381 , A61K45/06 , C07D333/08 , A61K2300/00
摘要： A compound represented by the general formula (C): (wherein R101 represents a substituted or unsubstituted aromatic heterocyclic group, R102, R103, R104 and R105 may be the same or different, and each represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, or a haloalkyl group having 1 to 3 carbon atoms, and R106 represents a hydrogen atom, or a saturated or unsaturated hydrocarbon group which is a straight or branched chain having 1 to 12 carbon atoms, but excluded is the case where R101 is a 3-furyl group, R102, R103, R104 and R105 are all methyl groups, and R106 is a methyl group, a 4-methyl-3-pentenyl group or a 4,8-dimethyl-3,7-nonadienyl group); or a pharmaceutically acceptable salt thereof has selective inhibitory activity on hypoxic cell growth in a broad range of the concentration and therefore is useful as an active ingredient of a medicament for cancer prevention or treatment.
摘要翻译： 由通式（C）表示的化合物：（其中R 101表示取代或未取代的芳族杂环基，R 102，R 103，R 104和R 105可以相同或不同，表示氢原子，卤素原子，烷基 具有1至3个碳原子的烷基或具有1至3个碳原子的卤代烷基，R 10 6表示氢原子，或具有1至12个碳原子的直链或支链的饱和或不饱和烃基，但不包括 R 101为3-呋喃基的情况，R102，R103，R104，R105均为甲基，R106为甲基，4-甲基-3-戊烯基或4,8-二甲基-3,7 - 壬二烯基）; 或其药学上可接受的盐在宽范围的浓度下对缺氧细胞生长具有选择性抑制活性，因此可用作用于癌症预防或治疗的药物的活性成分。
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