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14 条记录 (耗时 0.018 秒)

    Webbing take-up device
    1.
    发明授权
    Webbing take-up device 有权
    织带收卷装置

    公开(公告)号：US08376258B2

    公开(公告)日：2013-02-19

    申请号：US12904955

    申请日：2010-10-14

    申请人： Takayoshi Ando ,  Teruhiko Koide ,  Masafumi Tsujimoto

    发明人： Takayoshi Ando ,  Teruhiko Koide ,  Masafumi Tsujimoto

    IPC分类号： B65H75/48

    CPC分类号： B60R22/46 ,  B60R2022/468

    摘要： A webbing take-up device enabling a reduction in size of an overload release mechanism and easy adjustment of an operation torque of the overload release mechanism is provided. In the overload release mechanism of this webbing take-up device, rotary force of a large diameter gear is transmitted to a small diameter gear via plural annular friction springs. The friction springs are disposed between an inner periphery face of a main body portion of the large diameter gear and a tubular portion of the small diameter gear, side by side along an axial direction of the two gears. Consequently, a radial direction enlargement of the large diameter gear and small diameter gear due to space for disposing the friction springs may be restrained. Moreover, the operation torque of the overload release mechanism may be adjusted stepwise by changing the number of the friction springs to be used, in accordance with requirements.

    摘要翻译： 提供一种能够减小过载释放机构的尺寸并且容易调节过载释放机构的操作扭矩的织带卷取装置。 在这种织带卷取装置的过载释放机构中，大直径齿轮的旋转力通过多个环形摩擦弹簧传递到小直径齿轮。 摩擦弹簧沿着两个齿轮的轴向并排设置在大直径齿轮的主体部分的内周面和小直径齿轮的管状部分之间。 因此，可以抑制由于设置摩擦弹簧的空间而引起的大直径齿轮和小直径齿轮的径向扩大。 此外，可以根据要求通过改变要使用的摩擦弹簧的数量来逐步地调节过载释放机构的操作扭矩。

    Vector expressing n-deacetylase/n-sulfotransferase 2
    2.
    发明申请
    Vector expressing n-deacetylase/n-sulfotransferase 2 有权
    表达正 - 脱乙酰酶/正 - 磺基转移酶的载体2

    公开(公告)号：US20090053735A1

    公开(公告)日：2009-02-26

    申请号：US11658762

    申请日：2005-07-27

    申请人： Jun-ichi Aikawa ,  Masafumi Tsujimoto ,  Takuji Kaneko

    发明人： Jun-ichi Aikawa ,  Masafumi Tsujimoto ,  Takuji Kaneko

    IPC分类号： G01N33/573 ,  C12N9/10 ,  C12N15/00 ,  C12N5/00 ,  C12P21/04

    CPC分类号： C12N9/13 ,  C07K2319/02 ,  C07K2319/21 ,  C12N9/18 ,  C12N2799/026 ,  C12N2840/105 ,  C12N2840/75

    摘要： An object of the present invention is to provide an expression vector that allows for stable production of N-deacetylase/N-sulfotransferase 2 in large amounts and a process for production of N-deacetylase/N-sulfotransferase 2 using the same. The present invention provides a recombinant baculovirus expression vector obtained by incorporating into baculovirus DNA, a DNA fragment having lobster L21 DNA, DNA encoding gp67 signal peptide and DNA encoding the 79th to 883rd amino acids of human N-deacetylase/N-sulfotransferase 2 in this order in the 5′ to 3′ direction.

    摘要翻译： 本发明的目的在于提供能够大量稳定生产N-脱乙酰酶/ N-磺基转移酶2的表达载体和使用其的N-脱乙酰酶/ N-磺基转移酶2的制造方法。 本发明提供了通过将杆状病毒DNA，具有龙虾L21 DNA的DNA片段，编码gp67信号肽的DNA和编码人N-脱乙酰酶/ N-磺基转移酶2的第79〜883位氨基酸的DNA并入本发明而获得的重组杆状病毒表达载体 在5'到3'的方向。

    Sugar chain synthases
    3.
    发明申请
    Sugar chain synthases 审中-公开
    糖链合成酶

    公开(公告)号：US20060057696A1

    公开(公告)日：2006-03-16

    申请号：US10501930

    申请日：2003-01-30

    申请人： Shou Takashima ,  Masafumi Tsujimoto ,  Shuichi Tsuji

    发明人： Shou Takashima ,  Masafumi Tsujimoto ,  Shuichi Tsuji

    IPC分类号： C12N9/10 ,  C12P21/06

    CPC分类号： C12N9/1081

    摘要： The present invention provides O-glycan α2,8-sialyltransferase which has novel substrate specificity and substrate selectivity, and β-galactoside α2,6-sialyltransferase which has novel action and substrate specificity. The sialyltransferase of the present invention can be used as a medicament for suppression of cancer metastasis, prevention of virus infection, suppression of inflammatory response, or activation of neural cells.

    摘要翻译： 本发明提供具有新的底物特异性和底物选择性的O-聚糖α2,8-唾液酸转移酶，以及具有新作用和底物特异性的β-半乳糖苷α2,6-唾液酸转移酶。 本发明的唾液酸转移酶可以用作抑制癌转移，预防病毒感染，抑制炎性反应或神经细胞活化的药物。

    Oxidized phospholipid degrading enzyme and gene thereof
    5.
    发明授权
    Oxidized phospholipid degrading enzyme and gene thereof 失效
    氧化磷脂降解酶及其基因

    公开(公告)号：US5880272A

    公开(公告)日：1999-03-09

    申请号：US961716

    申请日：1997-10-31

    申请人： Hideki Adachi ,  Masafumi Tsujimoto ,  Keizo Inoue ,  Hiroyuki Arai

    发明人： Hideki Adachi ,  Masafumi Tsujimoto ,  Keizo Inoue ,  Hiroyuki Arai

    IPC分类号： C12N9/16 ,  C12N9/18 ,  C12N15/09 ,  C12N15/53 ,  C12N9/20 ,  C12N15/55

    CPC分类号： C12N9/18

    摘要： An oxidized phospholipid degrading enzyme is provided, which plays an important role in the oxygen stress preventive mechanism in organisms. The enzyme hydrolyzes a 1-acyl-2-.omega.-carboxyfatty acid acyl-3-phosphatidylcholine as a substrate at the 2-ester bond thereof to form 1-acyl-2-lyso-3-phosphatidylcholine. The activity of the enzyme is slightly enhanced by 4 mM calcium chloride. The molecular mass of the enzyme is 95.+-.5 kDa (by gel filtration). The enzyme is composed of three subunits whose molecular masses have been found to be 29 kDa, 30 kDa and 45 kDa, respectively, by SDS-polyacrylamide electrophoresis. A gene coding the enzyme is also provided. This gene is important for the synthesis of the enzyme by genetic engineering.

    摘要翻译： 提供氧化磷脂降解酶，在生物体的氧应激预防机制中起重要作用。 该酶水解1-酰基-2-巯基脂肪酸酰基-3-磷脂酰胆碱作为其2-酯键的底物，形成1-酰基-2-溶血-3-磷脂酰胆碱。 该酶的活性由4mM氯化钙稍微增强。 酶的分子量为95 +/- 5kDa（通过凝胶过滤）。 该酶由三个亚基组成，其分子量分别通过SDS-聚丙烯酰胺电泳发现为29kDa，30kDa和45kDa。 还提供了编码酶的基因。 该基因对通过遗传工程合成酶非常重要。