Pipetting device, fluid processing system and method for operating a fluid processing system

    公开(公告)号:US11161108B2

    公开(公告)日:2021-11-02

    申请号:US16307215

    申请日:2017-07-21

    Inventor: Philipp Ott

    Abstract: A pipetting device having a lube has an opening al one end for suctioning or discharging a sample fluid and can be operatively connected to a pressure generation device at the other end, a first electrode is formed on the pipetting device and forms a measuring capacitor together with a second electrode formed by at least one part of the sample fluid that can be received in the tube and that measuring capacitor is operatively connected to a measuring unit, and the measuring unit is designed to determine a volume of the suctioned or discharged sample fluid according to the capacity of the measuring capacitor, as well as having a first electrical contact that is designed to create an electrical connection with the working fluid, the first electrical contact can be electrically connected to the measuring unit via a low-resistance converter circuit.

    Method of treating a sample
    4.
    发明授权

    公开(公告)号:US12290804B2

    公开(公告)日:2025-05-06

    申请号:US17294853

    申请日:2018-12-20

    Abstract: A method of treating an isolated area of a sample with a liquid is disclosed. The method has the steps of generating an isolated area of a sample by a first fluid reservoir where the first fluid reservoir enclosing a distal end of a second fluid reservoir and the isolated area of the sample being sealed towards the remaining area of the sample, bringing the isolated area of the sample into fluid connection with the second fluid reservoir, dispensing a fluid from the second fluid reservoir into the first fluid reservoir thereby generating a fluid flow on the sample at the isolated area in a first direction, and aspirating the fluid from the first fluid reservoir into the second fluid reservoir thereby generating a fluid flow on the sample at the isolated area in a second direction.

    Pipette tip positioning with guiding frame

    公开(公告)号:US20250093376A1

    公开(公告)日:2025-03-20

    申请号:US18888828

    申请日:2024-09-18

    Abstract: A guiding frame for a laboratory automation device comprises: a bottom side for placing the guiding frame on a component of the laboratory automation device; a top side with a position detection area; and an opening for accessing a port of the component, which opening is arranged besides the position detection area. The position detection area has two recesses, each recess having two straight edges, which from a view direction onto the top side are arranged inclined with respect to each other. The bottom side comprises alignment means for aligning the guiding frame with respect to the component, the alignment means comprising a base surface for contacting a top surface of the component and/or guiding surfaces for contacting walls of the component.

    Pipetting device comprising a fluid volume sensor and fluid processing system

    公开(公告)号:US11311872B2

    公开(公告)日:2022-04-26

    申请号:US16309058

    申请日:2017-07-19

    Inventor: Philipp Ott

    Abstract: The invention relates to a pipetting device having tube with an opening at one end for suctioning or discharging a sample fluid, and can be operatively connected to a pressure generation device at the other end. A first electrode is formed on the pipetting device that forms a measuring capacitor together with a second electrode formed by at least one part of the sample fluid and that can be received in the tube and the measuring capacitor is operatively connected to a measuring unit, and the measuring unit is designed to determine a volume of the suctioned or discharged sample fluid according to the capacity of the measuring capacitor. The invention also relates to a fluid processing system having a pipetting device of this type, as well as a method for determining a processed fluid volume during pipetting with a pipetting device of this type.

    Pipetting apparatus, a liquid handling system and a method of controlling pipetting

    公开(公告)号:US11565249B2

    公开(公告)日:2023-01-31

    申请号:US16954414

    申请日:2018-12-12

    Inventor: Philipp Ott

    Abstract: A pipetting apparatus having a pipette tube with a first end provided with an opening for aspirating and/or dispensing of a sample fluid and a second end operationally connected to a pressure generating means. The pipetting apparatus has at least one measuring unit adapted to determine at least one measurement value of the sample fluid based on the aspirating and/or dispensing of the sample fluid and to provide a sample fluid measurement signal representative thereof to an output of the measuring unit. The pipetting apparatus also has a control circuit operationally coupled to the output of the measuring unit and the input of the pressure generating means, the control circuit is configured to control said pressure generating device based on the sample fluid measurement signal.

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