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1.发明授权Stented heart valve devices and methods for atrioventricular valve replacement 有权心脏瓣膜瓣膜置换装置及房室瓣置换方法公开(公告)号：US09510943B2
公开(公告)日：2016-12-06
申请号：US12009323
申请日：2008-01-17
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/82 , A61F2/852 , A61F2/958 , A61F2002/065 , A61F2002/8486 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0008 , A61F2230/001 , A61F2230/0017 , A61F2230/005 , A61F2230/0054 , A61F2250/0018 , A61F2250/0036 , A61F2250/0037 , A61F2250/0039 , A61F2250/0064 , A61F2250/0069
摘要： A compressible and expandable stent assembly for implantation in a body lumen such as a mitral valve, the stent assembly including at least one stent barrel that is shaped and sized so that it allows for normal operation of adjacent heart structures. One or more stent barrels can be included in the stent assembly, where one or more of the stent barrels can include a cylinder with a tapered edge.
摘要翻译： 一种用于植入体腔（例如二尖瓣）的可压缩和可扩展的支架组件，所述支架组件包括至少一个成形和尺寸使其允许相邻心脏结构的正常操作的支架筒。 一个或多个支架套筒可以包括在支架组件中，其中一个或多个支架套筒可以包括具有锥形边缘的圆柱体。
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2.发明申请Stented heart valve devices and methods for atrioventricular valve replacement 有权心脏瓣膜瓣膜置换装置及房室瓣置换方法公开(公告)号：US20080183273A1
公开(公告)日：2008-07-31
申请号：US12009323
申请日：2008-01-17
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/82 , A61F2/852 , A61F2/958 , A61F2002/065 , A61F2002/8486 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0008 , A61F2230/001 , A61F2230/0017 , A61F2230/005 , A61F2230/0054 , A61F2250/0018 , A61F2250/0036 , A61F2250/0037 , A61F2250/0039 , A61F2250/0064 , A61F2250/0069
摘要： A compressible and expandable stent assembly for implantation in a body lumen such as a mitral valve, the stent assembly including at least one stent barrel that is shaped and sized so that it allows for normal operation of adjacent heart structures. One or more stent barrels can be included in the stent assembly, where one or more of the stent barrels can include a cylinder with a tapered edge.
摘要翻译： 一种用于植入体腔（例如二尖瓣）的可压缩和可扩展的支架组件，所述支架组件包括至少一个成形和尺寸使其允许相邻心脏结构的正常操作的支架筒。 一个或多个支架套筒可以包括在支架组件中，其中一个或多个支架套筒可以包括具有锥形边缘的圆柱体。
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公开(公告)号：US20130072786A1
公开(公告)日：2013-03-21
申请号：US13585622
申请日：2012-08-14
申请人： James R. Keogh , Timothy R. Ryan , Carol E. Eberhardt , Mark T. Stewart , James R. Skarda , Timothy G. Laske , Alexander J. Hill , Jack D. Lemmon , David E. Francischelli
发明人： James R. Keogh , Timothy R. Ryan , Carol E. Eberhardt , Mark T. Stewart , James R. Skarda , Timothy G. Laske , Alexander J. Hill , Jack D. Lemmon , David E. Francischelli
IPC分类号： A61B6/12
CPC分类号： A61F2/2496 , A61B5/0044 , A61B5/1076 , A61B5/6853 , A61B8/445 , A61B18/1442 , A61B34/20 , A61B90/37 , A61B90/39 , A61B2017/00243 , A61B2018/00291 , A61B2018/00351 , A61B2018/00577 , A61B2034/2051 , A61B2034/2063 , A61B2090/378 , A61B2090/397 , A61F2/2433 , A61F2210/009 , A61F2250/0096 , A61N7/02
摘要： A device and method for valve replacement or valve repair is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding a valve replacement delivery member or a valve repair delivery member within the patient while tracking the position of the delivery member in the patient, positioning the valve replacement member or valve repair member in a desired position to replace a valve or repair valve and removing the delivery member from the patient.
摘要翻译： 公开了一种用于瓣膜置换或瓣膜修复的装置和方法，包括以下步骤：获取患者的解剖图像，将图像与患者相关联，在跟踪位置的同时引导患者内的瓣膜置换输送构件或瓣膜修复递送构件 的患者中的输送构件，将瓣膜置换构件或瓣膜修复构件定位在期望位置以更换瓣膜或修复瓣膜并从患者移除输送构件。
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公开(公告)号：US20100198346A1
公开(公告)日：2010-08-05
申请号：US12570888
申请日：2009-09-30
申请人： James R. Keogh , Timothy R. Ryan , Carol E. Eberhardt , Mark T. Stewart , James R. Skarda , Timothy G. Laske , Alexander J. Hill , Jack D. Lemmon , David E. Francischelli
发明人： James R. Keogh , Timothy R. Ryan , Carol E. Eberhardt , Mark T. Stewart , James R. Skarda , Timothy G. Laske , Alexander J. Hill , Jack D. Lemmon , David E. Francischelli
IPC分类号： A61F2/24
CPC分类号： A61F2/2496 , A61B5/0044 , A61B5/1076 , A61B5/6853 , A61B8/445 , A61B18/1442 , A61B34/20 , A61B90/37 , A61B90/39 , A61B2017/00243 , A61B2018/00291 , A61B2018/00351 , A61B2018/00577 , A61B2034/2051 , A61B2034/2063 , A61B2090/378 , A61B2090/397 , A61F2/2433 , A61F2210/009 , A61F2250/0096 , A61N7/02
摘要： A device and method for valve replacement or valve repair is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding a valve replacement delivery member or a valve repair delivery member within the patient while tracking the position of the delivery member in the patient, positioning the valve replacement member or valve repair member in a desired position to place a valve or repair valve and removing the delivery member from the patient. In one aspect of the invention, a delivery system is provided for percutaneous delivery of a heart valve to a predetermined position in the heart of a patient, where the delivery system itself includes features that allow it to be accurately positioned in the heart. In another aspect of the invention, a delivery system is provided for percutaneous repair of a heart valve in the heart of a patient, where the repair system itself includes features that allow it to be accurately positioned in the heart. In another aspect of the invention, a method and device are provided that involve imaging a native root using an interoperative technique, then introducing a device that is easily visualized in a chosen imaging modality.
摘要翻译： 公开了一种用于瓣膜置换或瓣膜修复的装置和方法，包括以下步骤：获取患者的解剖图像，将图像与患者相关联，在跟踪位置的同时引导患者内的瓣膜置换输送构件或瓣膜修复递送构件 的患者中的输送构件，将瓣膜置换构件或瓣膜修复构件定位在期望的位置以放置瓣膜或修复瓣膜并从患者移除输送构件。 在本发明的一个方面，提供一种用于将心脏瓣膜经皮递送到患者心脏中的预定位置的递送系统，其中递送系统本身包括允许其准确地定位在心脏中的特征。 在本发明的另一方面，提供一种用于经皮修复患者心脏中的心脏瓣膜的递送系统，其中所述修复系统本身包括允许其准确地定位在心脏中的特征。 在本发明的另一方面，提供了一种方法和装置，其涉及使用手术技术对本地根进行成像，然后引入在选择的成像模式中容易可视化的装置。
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公开(公告)号：US08241274B2
公开(公告)日：2012-08-14
申请号：US12570888
申请日：2009-09-30
申请人： James R. Keogh , Timothy R. Ryan , Carol E. Eberhardt , Mark T. Stewart , James R. Skarda , Timothy G. Laske , Alexander J. Hill , Jack D. Lemmon , David E. Francischelli
发明人： James R. Keogh , Timothy R. Ryan , Carol E. Eberhardt , Mark T. Stewart , James R. Skarda , Timothy G. Laske , Alexander J. Hill , Jack D. Lemmon , David E. Francischelli
IPC分类号： A61B18/04
CPC分类号： A61F2/2496 , A61B5/0044 , A61B5/1076 , A61B5/6853 , A61B8/445 , A61B18/1442 , A61B34/20 , A61B90/37 , A61B90/39 , A61B2017/00243 , A61B2018/00291 , A61B2018/00351 , A61B2018/00577 , A61B2034/2051 , A61B2034/2063 , A61B2090/378 , A61B2090/397 , A61F2/2433 , A61F2210/009 , A61F2250/0096 , A61N7/02
摘要： A device and method for valve replacement or valve repair is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding a valve replacement delivery member or a valve repair delivery member within the patient while tracking the position of the delivery member in the patient, positioning the valve replacement member or valve repair member in a desired position to place a valve or repair valve and removing the delivery member from the patient. In one aspect of the invention, a delivery system is provided for percutaneous delivery of a heart valve to a predetermined position in the heart of a patient, where the delivery system itself includes features that allow it to be accurately positioned in the heart. In another aspect of the invention, a delivery system is provided for percutaneous repair of a heart valve in the heart of a patient, where the repair system itself includes features that allow it to be accurately positioned in the heart. In another aspect of the invention, a method and device are provided that involve imaging a native root using an interoperative technique, then introducing a device that is easily visualized in a chosen imaging modality.
摘要翻译： 公开了一种用于瓣膜置换或瓣膜修复的装置和方法，包括以下步骤：获取患者的解剖图像，将图像与患者相关联，在跟踪位置的同时引导患者内的瓣膜置换输送构件或瓣膜修复递送构件 的患者中的输送构件，将瓣膜置换构件或瓣膜修复构件定位在期望的位置以放置瓣膜或修复瓣膜并从患者移除输送构件。 在本发明的一个方面，提供一种用于将心脏瓣膜经皮递送到患者心脏中的预定位置的递送系统，其中递送系统本身包括允许其准确地定位在心脏中的特征。 在本发明的另一方面，提供一种用于经皮修复患者心脏中的心脏瓣膜的递送系统，其中所述修复系统本身包括允许其准确地定位在心脏中的特征。 在本发明的另一方面，提供了一种方法和装置，其涉及使用手术技术对本地根进行成像，然后引入在选择的成像模式中容易可视化的装置。
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公开(公告)号：US20110054466A1
公开(公告)日：2011-03-03
申请号：US12771031
申请日：2010-04-30
申请人： Paul T. Rothstein , Cathleen A. Bergin , Cynthia T. Clague , Michael M. Green , Alexander J. Hill , James R. Keogh , Timothy G. Laske
发明人： Paul T. Rothstein , Cathleen A. Bergin , Cynthia T. Clague , Michael M. Green , Alexander J. Hill , James R. Keogh , Timothy G. Laske
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B18/1492 , A61B2018/00011 , A61B2018/143 , A61B2218/002 , A61B2218/007 , A61F2/82
摘要： An ablation catheter including an inner tube having a length, a distal end and a longitudinal axis, a plurality of needles extending from the distal end of the inner tube and biased away from the longitudinal axis, an outer sheath slideably moveable relative to the inner tube to surround at least a portion of the length of the inner tube and its extending needles, and a radio frequency energy source electrically connected to the plurality of needles.
摘要翻译： 一种消融导管，其包括具有长度，远端和纵向轴线的内管，从所述内管的远端延伸并偏离所述纵向轴线的多个针，相对于所述内管可滑动地移动的外护套 以围绕内管及其延伸针的长度的至少一部分，以及电连接到多个针的射频能量源。
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7.发明授权公开(公告)号：US08157853B2
公开(公告)日：2012-04-17
申请号：US12357980
申请日：2009-01-22
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2403 , A61F2/2412 , A61F2/243 , A61F2/2436 , A61F2/82 , A61F2002/9505 , A61F2002/9511 , A61F2250/0098
摘要： A method of deploying an implantable stented device in an anatomical location of a patient, including the steps of providing a delivery system with first and second stent engagement structures at its distal end, attaching a first structural element of the stented device to the first stent engagement structure and attaching a second structural element of the stented device to the second stent engagement structure, advancing the stented device to an implantation site, and sequentially disengaging the first structural element of the stented device from the first stent engagement structure of the delivery system and then disengaging the second structural element of the stented device from the second stent engagement structure.
摘要翻译： 一种将可植入支架装置部署在患者的解剖位置的方法，包括以下步骤：在其远端处提供具有第一和第二支架接合结构的输送系统，将支架装置的第一结构元件附接到第一支架接合 结构并将支架装置的第二结构元件附接到第二支架接合结构，将支架装置推进到植入部位，并且将支架装置的第一结构元件与递送系统的第一支架接合结构顺序地分离，然后 将支架装置的第二结构元件与第二支架接合结构分离。
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公开(公告)号：US20090287299A1
公开(公告)日：2009-11-19
申请号：US12321760
申请日：2009-01-23
申请人： Charles Tabor , Carol E. Eberhardt , Timothy G. Laske , Timothy R. Ryan , Joseph C. Morrow , Tammy Y. Tam , Brian A. Glynn , Anne L. Brody Rubin , J. Michael Tuchek
发明人： Charles Tabor , Carol E. Eberhardt , Timothy G. Laske , Timothy R. Ryan , Joseph C. Morrow , Tammy Y. Tam , Brian A. Glynn , Anne L. Brody Rubin , J. Michael Tuchek
CPC分类号： A61F2/2418 , A61F2/013 , A61F2/07 , A61F2/2433 , A61F2/2436 , A61F2/89 , A61F2/90 , A61F2002/016 , A61F2220/0058 , A61F2220/0075 , A61F2220/0091 , A61F2230/0006 , A61F2230/0054 , A61F2230/008 , A61F2250/0018 , A61F2250/003 , A61F2250/0039
摘要： A stented valve including a stent structure including a generally tubular body portion that has a first end and a second end, wherein an area adjacent the first end has a first stiffness, an area adjacent the second end has a second stiffness, and a central region between the areas at the first and second ends has a third stiffness that is less than the stiffness adjacent the first and second ends, wherein the stent structure can be reconfigured in its central area to match a curved patient anatomical region. The stented valve further includes a valve structure attached within the generally tubular portion.
摘要翻译： 一种支架式阀，包括支架结构，其包括具有第一端和第二端的大体管状体部，其中与第一端相邻的区域具有第一刚度，与第二端相邻的区域具有第二刚度，以及中心区域 在第一和第二端之间的区域之间具有小于邻近第一和第二端的刚度的第三刚度，其中支架结构可以在其中心区域重新配置以匹配弯曲的患者解剖区域。 支架瓣膜还包括附接在大致管状部分内的阀结构。
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公开(公告)号：US20090192585A1
公开(公告)日：2009-07-30
申请号：US12357958
申请日：2009-01-22
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2403 , A61F2/2412 , A61F2/243 , A61F2/2436 , A61F2/82 , A61F2002/9505 , A61F2002/9511 , A61F2250/0098
摘要： A delivery system for delivering a stented prosthetic heart valve to a lumen of a patient, the delivery system including a tubular body having a proximal end and a distal end, and a plurality of wires extending from the distal end of the tubular body, wherein each of the wires has a distal end that is coiled for engagement with a stent of a stented prosthetic heart valve.
摘要翻译： 一种用于将支架假体心脏瓣膜输送到患者的内腔的输送系统，所述输送系统包括具有近端和远端的管状体以及从所述管状体的远端延伸的多根线，其中每个 的线具有被卷绕以与支架假体心脏瓣膜的支架接合的远端。
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公开(公告)号：US08801706B2
公开(公告)日：2014-08-12
申请号：US12771031
申请日：2010-04-30
申请人： Paul T. Rothstein , Cathleen A. Bergin , Cynthia T. Clague , Michael M. Green , Alexander J. Hill , James R. Keogh , Timothy G. Laske
发明人： Paul T. Rothstein , Cathleen A. Bergin , Cynthia T. Clague , Michael M. Green , Alexander J. Hill , James R. Keogh , Timothy G. Laske
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B18/1492 , A61B2018/00011 , A61B2018/143 , A61B2218/002 , A61B2218/007 , A61F2/82
摘要： An ablation catheter including an inner tube having a length, a distal end and a longitudinal axis, a plurality of needles extending from the distal end of the inner tube and biased away from the longitudinal axis, an outer sheath slideably moveable relative to the inner tube to surround at least a portion of the length of the inner tube and its extending needles, and a radio frequency energy source electrically connected to the plurality of needles.
摘要翻译： 一种消融导管，其包括具有长度，远端和纵向轴线的内管，从所述内管的远端延伸并偏离所述纵向轴线的多个针，相对于所述内管可滑动地移动的外护套 以围绕内管及其延伸针的长度的至少一部分，以及电连接到多个针的射频能量源。
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