摘要:
An ink jet printing system has a low aspect ratio cylindrical drum adapted to support a sheet of material to be printed by a computer controlled printing head of a plurality of pigmented inks. The drum is preferably of approximately the same diameter as its axial length, is made up of at least two spoked wheel assemblies consisting of several arcuate wheel segment subassemblies that are joined together and held in place by a corregated skin covered with a fiberglass layup to provide a smooth cylindrical surface onto which the sheet material is spread. A clamping device is provided for tensioning the sheet material as it is rotated past a carriage carrying the printing head and affording two relative movement directions as between the printing head and the sheet to be printed for these differently colored printing inks.
摘要:
The present invention is directed to imidazolyl derivatives of formula (I) where the substituents are defined in the specification, which are useful as agonists or antagonists of somatostatin receptors.
摘要:
A compound or pharmaceutically acceptable salts thereof of Formula (I) wherein the substituents are as defined herein, which are useful as kinase inhibitors.
摘要:
The invention relates to the use of cysteine derivatives for preparing a medicament intended to treat diseases which result from the formation of the heterotrimeric G protein. These diseases include in particular diseases linked to the following biological functions or disorders: smell, taste, perception of the light, neurotransmission, neurodegeneration, endocrine and exocrine gland functions, autocrine and paracrine regulation, arterial tension, embryogenesis, benign cell proliferation, oncogenesis, viral infection, immunological functions, diabetes, obesity, and benign :and malign proliferative diseases. Said cysteine derivatives include in particular: bis-1,1′-[7-(2-amino-1-oxo-3-thiopropyl)-8-(cyclohexylmethyl)-2-(2-methoxyphenyl)-5,6,7,8-tetrahydroimidazo[1.2a]pyrazine disulphide (I), and bis-1,1′-7-(2-amino-1-oxo-3-thiopropyl-(2-(1-naphtyl)-8-(2-methylpropyl)-5,6,7,8-tetrahydroimidazo[1.2a]pyrazin-7-yl) disulphide (II).
摘要:
Novel compounds of Formula (I) or pharmaceutically acceptable salts, prodrugs and biologically active metabolites thereof of Formula (I) wherein the substituents are as defined herein, which are useful as therapeutic agents.
摘要:
A donor web for use in a thermal transfer printer comprises a foil having a transfer side and a non-transfer side. A layer of thermal transfer material is disposed on the transfer side of the foil material. Indicia is ink-jetted to the foil. The indicia includes information pertaining to at least one of the length of used foil and the length of unused foil so that an operator can determine whether there is enough foil left for a printing operation. Preferably, the indicia is disposed on the non-transfer side and at a longitudinal edge portion of the foil in order to not affect or otherwise damage the printing portion of the foil. Also, the indicia is preferably white or black ink in order to be clearly visible against various colors of the thermal transfer material. The indicia can also be disposed on a receiver web.
摘要:
Aspects of the invention related to a system for providing advance notice of impending contact between a stationary component and a rotating component in a turbine engine. For example, the system can be used to warn of potential contact between a seal holder and a rotor disk in the compressor section of the engine. In one embodiment, a pad or other component can be provided on the stationary seal holder. If the seal holder and the rotor disk approach each other during operation, the pad can contact the rotor disk prior to actual contact between the seal holder and the rotor disk. An optical and/or an acoustic signal can be generated by such contact. The signals can be detected remotely from the point of contact by a signal detection device, thereby avoiding the need to pass wires through the compressor section.
摘要:
The invention concerns a product inhibiting transduction of G heterotrimeric protein signals combined with another anti-cancer agent, in particular farnesyltransferase inhibitors, taxol or gemcitabin, for simultaneous, separate or prolonged therapeutic use in cancer treatment.
摘要:
Claimed is a somatostatin agonist according to formula (I), D-Phe-c(Cys-Tyr(I)-D-Trp-Lys-Val-Cys)-Thr-NH2, (I) or a pharmaceutically acceptable salt thereof, and uses thereof.