摘要:
Disclosed herein are methods of reducing infection of a cell by a pathogen, for example to treat or prevent a pathogen infection. Exemplary pathogens include those that use a lipid raft. The disclosure also relates to methods of identifying agents involved in pathogen infection, such as modulators of Rab9A and Rab11A.
摘要:
Host nucleic acids and host proteins that participate in viral infection, such as human immunodeficiency virus (HIV), influenza A, and Ebola virus, have been identified. Interfering with or disrupting the interaction between a host nucleic acid or host protein and a virus or viral protein confers an inhibition of or resistance to infection. Thus, interfering with such an interaction in a host subject can confer a therapeutic or prophylactic effect against a virus. The sequences identified can be used to identify agents that reduce or inhibit viral infection.
摘要:
The present invention relates generally to viral vaccines and, more specifically, to filovirus vaccines and methods of eliciting an immune response against a filovirus or disease caused by infection with filovirus.
摘要:
A fan housing includes a shroud defining an air passageway. A housing member is located adjacent the air passageway and moveably coupled to the shroud such that the housing member is moveable relative to the shroud between an operating position and a service position. A fan housing is defined by the housing member, whereby the fan housing is inaccessible when the housing member is in the operating position and the fan housing is accessible when the housing member is in the service position. The shroud and housing member may be coupled to an information handling system chassis and adjacent a heat producing component. A fan may then be positioned in the fan housing when the housing member is in the service position. The housing member is then moved to the operating position and the fan is operated in order to cool the heat producing component.
摘要:
Ebola virus vaccines comprising nucleic acid molecules encoding Ebola viral proteins are provided. In one embodiment, the nucleic acid molecule encodes the transmembrane form of the viral glycoprotein (GP). In another embodiment, the nucleic acid molecule encodes the secreted form of the viral glycoprotein (sGP). In yet another embodiment, the nucleic acid molecule encodes the viral nucleoprotein (NP). Methods for immunizing a subject against disease caused by infection with Ebola virus are also provided.
摘要:
In one embodiment, a media handling system is provided to transfer media through an image forming device having a primary media path and a duplex media path. The media handling system includes a media feeder configured to input media into the duplex media path of the image forming device.
摘要:
A peripheral device assembly is disclosed wherein the assembly includes a device bay for receiving a peripheral device carrier. An interior side surface of the device bay defines at least one extrusion portion surrounding a hole for receiving a first end of a lever arm of the peripheral device carrier, and the extrusion portion comprises edges protruding from the interior side surface of the device bay toward an exterior side surface of the device bay.
摘要:
The present invention relates generally to viral vaccines and, more specifically, to filovirus vaccines and methods of eliciting an immune response against a filovirus or disease caused by infection with filovirus.