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公开(公告)号：US09732724B1
公开(公告)日：2017-08-15
申请号：US15071704
申请日：2016-03-16
申请人： Thomas J. Burke
发明人： Thomas J. Burke
CPC分类号： F03B17/06 , F03B13/264 , F03D5/06 , F05B2210/16 , F05B2240/91 , F05B2240/931 , Y02E10/28
摘要： A reciprocating fluid-energy device to be used in a flowing fluid, having a foil, an upstream support member, a downstream support member, and a frame, where the frame retains the device in place within the flowing fluid, the support members movably attach the foil to the frame, and the foil moves laterally back and forth across the direction of the flow of the fluid, with changes in direction of the movement of the foil occurring automatically and spontaneously without external intervention other than the force of the flowing fluid.
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公开(公告)号：US08733860B1
公开(公告)日：2014-05-27
申请号：US13385855
申请日：2012-03-12
申请人： Thomas J. Burke , Ross Marrone , John Skurzynski
发明人： Thomas J. Burke , Ross Marrone , John Skurzynski
CPC分类号： B65G1/127 , A47B63/067 , A47F1/00 , A47F3/08 , A47F5/03
摘要： A storage system comprising a plurality of shelf units movable together through a circuit attached to and moved by a flexible drive such as a chain or belt, while being guided and stabilized in orientation by a separate guide track which track followers, retained by each shelf unit, move to maintain a selected orientation of the shelves within a system support or enclosure. Each shelf unit is removable by the user from engagement of the drive and from the system enclosure permitting replacement of the shelves within the storage system without system disassembly.
摘要翻译： 一种存储系统，包括多个搁架单元，所述搁板单元可通过连接到柔性驱动器（例如链条或带）的电路移动在一起，同时通过由每个搁架单元保持的跟踪器的单独的导轨被引导和稳定地定向 移动以在系统支持或机箱内维护货架的选定方位。 每个搁架单元可由用户移除，以免驱动器和系统外壳的接合，从而可以在不进行系统拆卸的情况下更换存储系统内的货架。
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公开(公告)号：US20130040302A1
公开(公告)日：2013-02-14
申请号：US13546365
申请日：2012-07-11
CPC分类号： C12N5/0696 , C12N15/907 , C12N2501/15 , C12N2501/235 , C12N2501/415 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/605 , C12N2501/606 , C12N2501/608 , C12N2501/727 , C12N2506/1307
摘要： Methods for producing engineered induced pluripotent stem (iPS) cells are provided comprising introducing a first nucleic acid into somatic cells for integration into their genome and reprogramming the cells to produce engineered iPS cells having the nucleic acid integrated into their genome. For example, in certain aspects the cells are reprogrammed by introduction of a genetic element that expresses one or more reprogramming factor and culturing of the cells under conditions sufficient to produce reprogrammed cells.
摘要翻译： 提供了用于产生工程化诱导多能干细胞（iPS）细胞的方法，包括将第一核酸引入体细胞用于整合到其基因组中并重新编程细胞以产生具有整合入其基因组中的核酸的工程化iPS细胞。 例如，在某些方面，通过引入表达一种或多种重编程因子的遗传元件并在足以产生重编程细胞的条件下培养细胞来重新编程细胞。
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公开(公告)号：US07356966B2
公开(公告)日：2008-04-15
申请号：US10891746
申请日：2004-07-15
申请人： Thomas J. Burke
发明人： Thomas J. Burke
IPC分类号： E01F13/00
摘要： An articulate railroad grade crossing assembly. In a preferred embodiment, the crossing assembly has an adjustable reach so that it can be adjusted to completely or partially close roadways of various sizes. In another preferred embodiment, the assembly includes one or more sensors for detecting the presence of people and/or objects in the crossing area so that the assembly can automatically respond to such presence.
摘要翻译： 一个清晰的铁路等级交叉装配。 在优选实施例中，交叉组件具有可调节的距离，使得其可以被调节成完全或部分地关闭各种尺寸的道路。 在另一个优选实施例中，组件包括用于检测交叉区域中的人和/或物体的存在的一个或多个传感器，使得组件可以自动地响应于这种存在。
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公开(公告)号：US06348090B1
公开(公告)日：2002-02-19
申请号：US09661655
申请日：2000-09-14
申请人： Susan M. Grillo , Brian Korchok , Bruce Kinsey , Stuart C. Porter , George Reyes , Thomas J. Burke , Charles Cunningham
发明人： Susan M. Grillo , Brian Korchok , Bruce Kinsey , Stuart C. Porter , George Reyes , Thomas J. Burke , Charles Cunningham
IPC分类号： C09D10302
摘要： A dry film coating composition for forming a coating suspension for film coating nutritional supplements, pharmaceutical tablets, and the like, including tapica dextrin and a detackifier.
摘要翻译： 一种干膜涂料组合物，用于形成用于薄膜包衣的营养补充剂，药物片剂等的包衣悬浮液，包括tapica糊精和防粘剂。
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公开(公告)号：US5483654A
公开(公告)日：1996-01-09
申请号：US122861
申请日：1993-09-15
IPC分类号： G06F9/44
CPC分类号： G06F9/4443
摘要： A "navigation protocol" is implemented via a computer program to provide communication and invocation capability among object-oriented application programs and precompiled library routines, collectively referred to as `programs`. Each application program is "registered" with the operating environment during its installation; registration entails updating a registration-table data structure with information about 1) a program identifier; 2) an object-type identifier identifying a class of objects; and 3) an action identifier, e.g., a menu entry, identifying an action which the program can perform on objects of the class specified by the object-type identifier. A user can manipulate an object by selecting the object and requesting that a list of all actions performable on the object be displayed, then selecting one of the displayed possible actions. The displayed actions are actually performed by programs as specified in the registration table; the user need not be concerned with knowing which program to invoke. Programs from a variety of different vendors can interact without any one program needing to know about any other program. This modularity uncouples the development process of the user's system from that of the organizations providing the individual development tools and allows the user to upgrade individual programs as desired.
摘要翻译： 通过计算机程序实现“导航协议”，以便在面向对象的应用程序和预编译库例程之间提供通信和调用能力，统称为“程序”。 每个应用程序在安装过程中都具有操作环境“注册” 注册需要更新具有关于1）节目标识符的信息的注册表数据结构; 2）识别对象类的对象类型标识符; 以及3）动作标识符，例如菜单条目，标识程序可以对由对象类型标识符指定的类的对象执行的动作。 用户可以通过选择对象并请求显示对象上可执行的所有操作的列表，然后选择所显示的可能动作之一来操纵对象。 显示的动作实际上由注册表中指定的程序执行; 用户不需要关心知道要调用哪个程序。 来自各种不同供应商的程序可以进行交互，而无需任何程序需要知道任何其他程序。 该模块化将用户系统的开发过程与提供各个开发工具的组织的开发流程相结合，并允许用户根据需要升级单个程序。
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公开(公告)号：US20090111709A1
公开(公告)日：2009-04-30
申请号：US12260537
申请日：2008-10-29
IPC分类号： C40B30/04
CPC分类号： C40B30/04 , G01N33/6845
摘要： The present invention relates to novel methods of the quantitative detection of molecules in an array. In particular, the present invention relates to methods for molecular detection assays performed on solid surfaces. The present invention provides improved methods for the high throughput analysis of molecular interactions and quantitative detection. In another aspect, the invention relates to a method of measuring protein interactions on a solid surface that is useful for the determination of equilibrium binding and rate constants. In yet another aspect, the invention relates to predicting a molecules utility in a detection assay.
摘要翻译： 本发明涉及定量检测阵列中分子的新方法。 特别地，本发明涉及在固体表面上进行的分子检测测定方法。 本发明提供了用于分子相互作用和定量检测的高通量分析的改进方法。 在另一方面，本发明涉及测量固体表面上的蛋白质相互作用的方法，其用于测定平衡结合和速率常数。 在另一方面，本发明涉及在检测测定中预测分子效用。
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公开(公告)号：US20090075837A1
公开(公告)日：2009-03-19
申请号：US12233140
申请日：2008-09-18
CPC分类号： G01N33/543 , C40B30/04 , G01N33/6845
摘要： The present invention relates to novel methods for the quantitative detection of molecules in an array. In particular, the present invention relates to methods and apparatuses for producing a frameless array. In another embodiment, the present invention relates to a composition comprising nitrocellulose that is useful of producing a frameless array. In another embodiment, the present invention relates to a method for detecting a molecular interaction. In yet another embodiment, the present invention relates to kits useful for practicing the methods and apparatuses of the present invention. The present invention provides improved methods and apparatuses for the high throughput analysis of molecular interactions and quantitative detection.
摘要翻译： 本发明涉及用于定量检测阵列中分子的新方法。 特别地，本发明涉及无框架阵列的制造方法和装置。 在另一个实施方案中，本发明涉及可用于生产无框架阵列的包含硝酸纤维素的组合物。 在另一个实施方案中，本发明涉及用于检测分子相互作用的方法。 在另一个实施方案中，本发明涉及可用于实施本发明的方法和装置的试剂盒。 本发明提供了用于分子相互作用和定量检测的高通量分析的改进的方法和装置。
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公开(公告)号：US06991552B2
公开(公告)日：2006-01-31
申请号：US10133790
申请日：2002-04-25
申请人： Thomas J. Burke
发明人： Thomas J. Burke
IPC分类号： A63B69/36
CPC分类号： A63B69/3635 , A63B69/0024 , A63B2071/0625 , A63B2071/0627
摘要： An overswing alerting mechanism/swing monitoring device that a user can wear, for example on the wrist, hand or arm, that can determine swing formation, and that can display and/or store the determined swing information. As an option, the device includes a visual and/or audible indicator for alerting the user to an improper swinging motion.
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10.发明授权Golf overswing alerting mechanism and golf club with overswing alerting mechanism 有权高尔夫挥杆警报机制和高尔夫球杆与超音速警报机制公开(公告)号：US06413167B1
公开(公告)日：2002-07-02
申请号：US09436582
申请日：1999-11-09
申请人： Thomas J. Burke
发明人： Thomas J. Burke
IPC分类号： A63B5700
CPC分类号： A63B69/3635 , A63B2071/0625 , A63B2071/0627
摘要： A golf overswing alerting mechanism is provided which produces a visual and/or audible indicator for the purpose of alerting a golfer to an improper swinging movement of a golf club. The overswing alerting mechanism is housed entirely within the hollow opening of the golf club shaft or is accommodated in a housing that is detachably affixed to the golf club. In a preferred configuration, the alerting mechanism includes a sound generation assembly for generating an audible sound upon occurrence of the overswing condition; an energy generation member to provide electrical energy to the sound generation assembly, and a circuit closing member or accelerometer(s) detecting the occurrence of an overswing condition. The preferred mechanism further includes an LCD readout provided in the grip butt of the golf club grip which indicates to the golfer the speed of the golf club shaft.
摘要翻译： 提供了一种高尔夫球翻转警报机制，其产生视觉和/或听觉指示器，用于警示高尔夫球手对高尔夫球杆的不正确摆动的运动。 翻转报警机构完全容纳在高尔夫球杆杆的中空开口内，或者容纳在可拆卸地固定在高尔夫球杆上的壳体中。 在优选的结构中，警报机构包括：声音发生组件，用于在发生过渡条件时产生可听见的声音; 为声音产生组件提供电能的能量产生部件，以及检测出现过载条件的电路关闭部件或加速度计。 优选的机构还包括设置在高尔夫球杆把手的把柄中的LCD读数器，其向高尔夫球手指示高尔夫球杆杆的速度。
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