专利检索 ap:("Thomas M. DiMauro" OR "Jeffrey K. Sutton" OR "Mohamed Attawia" OR "Hassan Serhan" OR "John Daniel Malone" OR "Timothy Beardsley") AND inv:"Hassan Serhan" 第 1 页

1.

发明授权
Photocatalytic implant having a sensor 有权
标题翻译：具有传感器的光催化植入物

公开(公告)号：US08267883B2

公开(公告)日：2012-09-18

申请号：US12817585

申请日：2010-06-17

申请人： Thomas M. DiMauro , Jeffrey K. Sutton , Mohamed Attawia , Hassan Serhan , John Daniel Malone , Timothy Beardsley

发明人： Thomas M. DiMauro , Jeffrey K. Sutton , Mohamed Attawia , Hassan Serhan , John Daniel Malone , Timothy Beardsley

IPC分类号： A61M5/00 , A61N1/30 , A61F2/00 , A62B7/08

CPC分类号： A61L31/146 , A61B17/866 , A61F2/30767 , A61F2/34 , A61F2/36 , A61F2/3662 , A61F2/38 , A61F2/4455 , A61F2002/30663 , A61F2002/30929 , A61F2002/30981 , A61F2002/3611 , A61F2002/3625 , A61F2002/443 , A61F2310/00023 , A61F2310/00604 , A61F2310/0061 , A61F2310/00616 , A61L27/06 , A61L27/427 , A61L27/56 , A61L31/022 , A61L31/124 , A61M5/158 , A61N5/0601 , A61N5/0624 , A61N2005/0651 , A61N2005/0661 , B01J35/004

摘要： An implant comprises a photocatalytic layer on at least one surface and is adapted to act as a sensor. In some embodiments, the photocatalytic layer is a semiconductor oxide that is doped. According to some embodiments, the implant comprises a wave guide. According to some embodiments the implant comprises a light port. According to some embodiments, the implant comprises a reflective material on a surface of the waveguide. According to some embodiments the implant comprises a composite material comprising a first material that has a transmissivity when exposed to a predetermined wavelength of light and a second material that has photocatalytic activity when exposed to the predetermined wavelength of light. According to some embodiments the implant comprises a light source adapted to irradiate the photocatalytic surface.

摘要翻译： 植入物包括在至少一个表面上的光催化层，并且适于作为传感器。在一些实施方案中，光催化层是掺杂的半导体氧化物。根据一些实施例，植入物包括波导。根据一些实施例，植入物包括光端口。根据一些实施例，植入物在波导的表面上包括反射材料。根据一些实施例，植入物包括复合材料，其包括当暴露于预定波长的光时具有透射率的第一材料和当暴露于预定波长的光时具有光催化活性的第二材料。根据一些实施例，植入物包括适于照射光催化表面的光源。

2.

发明申请
Photocatalytic Implant Having a Sensor 有权
标题翻译：具有传感器的光催化植入物

公开(公告)号：US20100317948A1

公开(公告)日：2010-12-16

申请号：US12817585

申请日：2010-06-17

申请人： Thomas M. DiMauro , Jeffrey K. Sutton , Mohamed Attawia , Hassan Serhan , John Daniel Malone , Timothy Beardsley

发明人： Thomas M. DiMauro , Jeffrey K. Sutton , Mohamed Attawia , Hassan Serhan , John Daniel Malone , Timothy Beardsley

IPC分类号： A61B5/1459

CPC分类号： A61L31/146 , A61B17/866 , A61F2/30767 , A61F2/34 , A61F2/36 , A61F2/3662 , A61F2/38 , A61F2/4455 , A61F2002/30663 , A61F2002/30929 , A61F2002/30981 , A61F2002/3611 , A61F2002/3625 , A61F2002/443 , A61F2310/00023 , A61F2310/00604 , A61F2310/0061 , A61F2310/00616 , A61L27/06 , A61L27/427 , A61L27/56 , A61L31/022 , A61L31/124 , A61M5/158 , A61N5/0601 , A61N5/0624 , A61N2005/0651 , A61N2005/0661 , B01J35/004

摘要： An implant comprises a photocatalytic layer on at least one surface and is adapted to act as a sensor. In some embodiments, the photocatalytic layer is a semiconductor oxide that is doped. According to some embodiments, the implant comprises a wave guide. According to some embodiments the implant comprises a light port. According to some embodiments, the implant comprises a reflective material on a surface of the waveguide. According to some embodiments the implant comprises a composite material comprising a first material that has a transmissivity when exposed to a predetermined wavelength of light and a second material that has photocatalytic activity when exposed to the predetermined wavelength of light. According to some embodiments the implant comprises a light source adapted to irradiate the photocatalytic surface.

摘要翻译： 植入物包括在至少一个表面上的光催化层，并且适于作为传感器。在一些实施方案中，光催化层是掺杂的半导体氧化物。根据一些实施例，植入物包括波导。根据一些实施例，植入物包括光端口。根据一些实施例，植入物在波导的表面上包括反射材料。根据一些实施例，植入物包括复合材料，其包括当暴露于预定波长的光时具有透射率的第一材料和当暴露于预定波长的光时具有光催化活性的第二材料。根据一些实施例，植入物包括适于照射光催化表面的光源。

3.

发明授权
Implant having a photocatalytic unit 有权
标题翻译：植入物具有光催化单元

公开(公告)号：US07744555B2

公开(公告)日：2010-06-29

申请号：US10774105

申请日：2004-02-06

申请人： Thomas M. DiMauro , Jeffrey K. Sutton , Mohamed Attawia , Hassan Serhan , John Daniel Malone , Tim Beardsley

发明人： Thomas M. DiMauro , Jeffrey K. Sutton , Mohamed Attawia , Hassan Serhan , John Daniel Malone , Tim Beardsley

IPC分类号： A61M5/00 , A61N1/30 , A61F2/00 , A62B7/08

CPC分类号： A61F2/30767 , A61B17/866 , A61F2/34 , A61F2/36 , A61F2/3662 , A61F2/38 , A61F2/4455 , A61F2002/30663 , A61F2002/30668 , A61F2002/30929 , A61F2002/30981 , A61F2002/3611 , A61F2002/3625 , A61F2002/443 , A61F2250/0001 , A61F2310/00023 , A61F2310/00604 , A61F2310/0061 , A61F2310/00616 , A61L27/06 , A61L27/427 , A61L27/56 , A61L31/022 , A61L31/124 , A61L31/146 , A61M5/158 , A61N5/0601 , A61N5/0624 , A61N2005/0651 , A61N2005/0661 , B01J35/004

摘要： An implant comprises a photocatalytic layer on at least one surface. In some embodiments, the photocatalytic layer is a semiconductor oxide that is doped. According to some embodiments, the implant comprises a wave guide. According to some embodiments the implant comprises a light port. According to some embodiments, the implant comprises a reflective material on a surface of the waveguide. According to some embodiments the implant comprises a composite material comprising a first material that has a transmissivity when exposed to a predetermined wavelength of light and a second material that has photocatalytic activity when exposed to the predetermined wavelength of light. According to some embodiments the implant comprises a light source adapted to irradiate the photocatalytic surface.

摘要翻译： 植入物包括在至少一个表面上的光催化层。在一些实施方案中，光催化层是掺杂的半导体氧化物。根据一些实施例，植入物包括波导。根据一些实施例，植入物包括光端口。根据一些实施例，植入物在波导的表面上包括反射材料。根据一些实施例，植入物包括复合材料，其包括当暴露于预定波长的光时具有透射率的第一材料和当暴露于预定波长的光时具有光催化活性的第二材料。根据一些实施例，植入物包括适于照射光催化表面的光源。

4.

发明申请
Intracranial Implant Emitting Light Between 450 nm and 600 nm 审中-公开
标题翻译：颅内植入发射光在450nm和600nm之间

公开(公告)号：US20100268151A1

公开(公告)日：2010-10-21

申请号：US12727794

申请日：2010-03-19

申请人： Christoph Mauge , Thomas M. DiMauro , Mohamed Attawia , Hassan Serhan , Jeffrey Sutton , Timothy Beardsley , Alan Dextradeur , Robert Kraus

发明人： Christoph Mauge , Thomas M. DiMauro , Mohamed Attawia , Hassan Serhan , Jeffrey Sutton , Timothy Beardsley , Alan Dextradeur , Robert Kraus

IPC分类号： A61N5/06

CPC分类号： A61M27/006 , A61M25/0045 , A61M2025/0056 , A61N5/0601 , A61N5/062 , A61N2005/0651 , A61N2005/0659 , A61N2005/0661

摘要： An intracranial implant emitting light having a wavelength between blue and yellow light

摘要翻译： 发射具有蓝色和黄色光之间的波长的光的颅内植入物

5.

发明授权
Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor 有权
标题翻译：局部骨内施用骨形成剂和抗吸收剂及其装置

公开(公告)号：US08895540B2

公开(公告)日：2014-11-25

申请号：US10723250

申请日：2003-11-26

申请人： Thomas M. DiMauro , Mohamed Attawia , Hassan Serhan , Melissa Grace , Michael Slivka , Thomas G. Ferro , Vivek N. Shenoy , Alonzo D. Cook , Scott Bruder

发明人： Thomas M. DiMauro , Mohamed Attawia , Hassan Serhan , Melissa Grace , Michael Slivka , Thomas G. Ferro , Vivek N. Shenoy , Alonzo D. Cook , Scott Bruder

IPC分类号： A01N45/00 , A61K45/06 , A61K33/42 , A61K38/39 , A61K31/565 , A61K39/395 , A61K38/18 , A61K31/566 , A61B17/34 , A61K9/00 , A61M5/145 , A61M5/142 , A61F2/30 , A61F2/28

CPC分类号： A61K33/42 , A61B17/3472 , A61F2002/2817 , A61F2002/30677 , A61K9/0004 , A61K31/565 , A61K31/566 , A61K38/1825 , A61K38/1875 , A61K38/39 , A61K39/395 , A61K45/06 , A61M5/14276 , A61M2005/14513 , A61K2300/00

摘要： This invention relates to local administration of a bone-forming agent and at least one anti-resorptive agent to treat osteoporosis and related disorders.

摘要翻译： 本发明涉及局部施用骨形成剂和至少一种抗再吸收剂来治疗骨质疏松症和相关疾病。

6.

发明授权
Transdiscal administration of anti-TNFα antibodies and growth differentiation factors 有权
标题翻译：反式TNFα抗体和生长分化因子的经半径给药

公开(公告)号：US08877193B2

公开(公告)日：2014-11-04

申请号：US12290998

申请日：2008-11-05

申请人： Hassan Serhan , Mohamed Attawia , Thomas M. DiMauro , Sudhakar Kadiyala , David Urbahns , Scott Bruder

发明人： Hassan Serhan , Mohamed Attawia , Thomas M. DiMauro , Sudhakar Kadiyala , David Urbahns , Scott Bruder

IPC分类号： A61K39/00 , A61K39/395 , A61K38/17

CPC分类号： A61K35/28 , A61B5/055 , A61B17/7061 , A61K9/0012 , A61K9/0019 , A61K9/0085 , A61K35/32 , A61K38/17 , A61K38/1793 , A61K38/18 , A61K38/1841 , A61K38/1875 , A61K38/20 , A61K38/363 , A61K38/4833 , A61K39/395 , A61K39/3955 , A61K45/06 , A61K47/34 , C12Y304/21005 , G01N33/6869 , G01N2333/54

摘要： The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.

摘要翻译： 本发明涉及将高特异性细胞因子拮抗剂注射到患病的椎间盘中。

7.

发明授权
Autologous treatment of degenerated disc with cells 有权
标题翻译：退化椎间盘自体治疗细胞

公开(公告)号：US08273347B2

公开(公告)日：2012-09-25

申请号：US10714594

申请日：2003-11-14

申请人： Mohamed Attawia , Hassan Serhan , Thomas M. DiMauro , Melissa Grace , David Urbahns

发明人： Mohamed Attawia , Hassan Serhan , Thomas M. DiMauro , Melissa Grace , David Urbahns

IPC分类号： A61K35/28 , A61K38/18

CPC分类号： A61K35/19 , A61K35/28 , A61K35/32 , A61K35/33 , A61K38/1841 , A61K2300/00

摘要： The present invention relates to administering autologous uncultured cells into a diseased intervertebral disc.

摘要翻译： 本发明涉及将自体未培养的细胞施用于患病的椎间盘。

8.

发明申请
Transdiscal administration of specific inhibitors of pro-inflammatory cytokines 有权
标题翻译：跨时间给药促炎细胞因子的特异性抑制剂

公开(公告)号：US20090175943A1

公开(公告)日：2009-07-09

申请号：US12291378

申请日：2008-11-07

申请人： Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Scott Bruder

发明人： Mohamed Attawia , Thomas M. DiMauro , Hassan Serhan , Sudhakar Kadiyala , David Urbahns , Scott Bruder

IPC分类号： A61K9/10 , A61K39/395

CPC分类号： A61K35/28 , A61B5/055 , A61B17/7061 , A61K9/0012 , A61K9/0019 , A61K9/0085 , A61K35/32 , A61K38/17 , A61K38/1793 , A61K38/18 , A61K38/1841 , A61K38/1875 , A61K38/20 , A61K38/363 , A61K38/4833 , A61K39/395 , A61K39/3955 , A61K45/06 , A61K47/34 , C12Y304/21005 , G01N33/6869 , G01N2333/54

摘要： The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.

摘要翻译： 本发明涉及将高特异性细胞因子拮抗剂注射到患病的椎间盘中。

9.

发明授权
Transdiscal administration of high affinity anti-MMP inhibitors 有权
标题翻译：跨度给药高亲和力抗MMP抑制剂

公开(公告)号：US07429378B2

公开(公告)日：2008-09-30

申请号：US10610355

申请日：2003-06-30

申请人： Hassan Serhan , Thomas M. DiMauro , Mohamed Attawia , Sudhakar Kadiyala , David Urbahns , Scott Bruder , Laura J. Brown , Jeffrey C. Geesin

发明人： Hassan Serhan , Thomas M. DiMauro , Mohamed Attawia , Sudhakar Kadiyala , David Urbahns , Scott Bruder , Laura J. Brown , Jeffrey C. Geesin

IPC分类号： A61K35/00

CPC分类号： A61K38/1841 , A61K35/28 , A61K38/57 , A61K2300/00

摘要： The present invention relates to injecting a high affinity antagonist of MMPs into a diseased intervertebral disc.

摘要翻译： 本发明涉及将MMP的高亲和力拮抗剂注射到患病的椎间盘中。