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126 条记录 (耗时 0.024 秒)

    Indoline and 1,2,3,4-tetrahydroquinoline N(dicarboalkoxyvinyl) substituted derivatives
    2.
    发明授权
    Indoline and 1,2,3,4-tetrahydroquinoline N(dicarboalkoxyvinyl) substituted derivatives 失效
    二氢吲哚和1,2,3,4-四氢喹啉N（二羧基烷氧基乙烯基）取代的衍生物

    公开(公告)号：US4792609A

    公开(公告)日：1988-12-20

    申请号：US866039

    申请日：1986-05-21

    申请人： Thomas Scholl ,  Otto Exner ,  Peter Finkel ,  Hermann Perrey

    发明人： Thomas Scholl ,  Otto Exner ,  Peter Finkel ,  Hermann Perrey

    IPC分类号： A61K8/00 ,  A61K8/49 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q1/06 ,  A61Q17/04 ,  C07D209/08 ,  C07D209/10 ,  C07D209/18 ,  C07D215/06

    CPC分类号： A61Q17/04 ,  A61K8/492 ,  C07D209/08 ,  C07D215/06

    摘要： An indoline derivative of the formula (I) ##STR1## in which R.sup.1 denotes H or C.sub.1 -C.sub.8 -alkyl;R.sup.2 and R.sup.3 are identical or different and denote C.sub.1 -C.sub.8 -alkyl;R.sup.4 -R.sup.9 are identical or different and denote H, C.sub.1 -C.sub.8 -alkyl, C.sub.5 -C.sub.6 -cycloalkyl or phenyl-C.sub.1 -C.sub.4 -alkyl, or R.sup.5 and R.sup.6 connected together to form a further C.sub.5 -C.sub.6 ring, andR.sup.10 denotes H or one or more radicals selected from the group consisting of C.sub.1 -C.sub.8 -alkyl, C.sub.1 -C.sub.8 alkoxy, C.sub.5 -C.sub.6 -cycloalkyl, phenyl-C.sub.1 -C.sub.4 -alkyl and carb-C.sub.1 -C.sub.8 -alkoxy radicals, or halogen atoms. Such indoline derivative is useful as a UV absorber.

    摘要翻译： 式（I）的二氢吲哚衍生物其中R 1表示H或C 1 -C 8 - 烷基; R2和R3相同或不同，表示C1-C8-烷基; R4-R9相同或不同，表示H，C1-C8-烷基，C5-C6-环烷基或苯基-C1-C4-烷基，或R5和R6连接在一起形成另外的C5-C6环，R10表示H 或选自C 1 -C 8 - 烷基，C 1 -C 8烷氧基，C 5 -C 6 - 环烷基，苯基-C 1 -C 4烷基和C 1 -C 8 - 烷氧基的一个或多个基团或卤原子。 这种二氢吲哚衍生物可用作UV吸收剂。

    Condensation products of thioalkylene oxides of polythio-alkylene oxides with polyalkylene oxides, their preparation and their use as breakers for water-in-oil emulsions
    4.
    发明授权
    Condensation products of thioalkylene oxides of polythio-alkylene oxides with polyalkylene oxides, their preparation and their use as breakers for water-in-oil emulsions 失效
    聚硫化烯氧化物的硫代环氧烷与聚环氧烷的缩合产物，它们的制备及其作为油包水乳液的破乳剂的用途

    公开(公告)号：US4745175A

    公开(公告)日：1988-05-17

    申请号：US821568

    申请日：1986-01-22

    申请人： Thomas Scholl ,  Wolfgang Oberkirch ,  Hermann Perrey

    发明人： Thomas Scholl ,  Wolfgang Oberkirch ,  Hermann Perrey

    IPC分类号： C08G65/34 ,  C08G81/00 ,  C10G33/04 ,  C10M105/08

    CPC分类号： C10G33/04 ,  C08G65/34 ,  C08G81/00

    摘要： New sulphur-containing polyethers based on optionally polymeric thioalkylene oxides and polyalkylene oxides, method for their preparation and their use as breakers for water-in-oil emulsions, in particular, as breakers for crude oil emulsions. The polyethers are of the formula ##STR1## in which R.sub.1 and R.sub.2, independently of each other, represent hydrogen and/or a straight-chain or branched C.sub.1 to C.sub.20 alkyl group,R.sub.3 and R.sub.4, independently of each other and independently of adjacent ##STR2## groups, represent in each case hydrogen, a straight-chain or branched C.sub.1 to C.sub.20 alkyl group and/or for --A--O--B, whereA denotes a straight-chain or branched C.sub.1 to C.sub.20 alkylene group andB denotes a straight-chain or branched C.sub.1 to C.sub.20 alkylene-OH group or a ##STR3## group with R.sub.1 and R.sub.2 as defined above, n represents an integer from 1 to 100 andm represents an integer from 10 to 2,500.

    摘要翻译： 基于任选的聚合硫代亚烷基氧化物和聚环氧烷的新型含硫聚醚，其制备方法及其作为油包水乳液的破乳剂，特别是作为原油乳液的破碎剂。 聚醚具有式（I）的化合物，其中R 1和R 2彼此独立地表示氢和/或直链或支链C 1至C 20烷基，R 3和R 4彼此独立地且独立地 相邻的“IMAGE”基团表示氢，直链或支链C1至C20烷基和/或-AOB，其中A表示直链或支链C1至C20亚烷基，B表示直链 链或支链C1至C20亚烷基-OH基团或具有如上定义的R1和R2的基团，n表示1至100的整数，m表示10至2,500的整数。

    FILTER DEVICE
    6.
    发明申请
    FILTER DEVICE 有权
    过滤器

    公开(公告)号：US20130292310A1

    公开(公告)日：2013-11-07

    申请号：US13261693

    申请日：2011-11-19

    申请人： Richard Eberle ,  Micha Kreibig ,  Thomas Scholl ,  Markus Dewes ,  Sven Brall

    发明人： Richard Eberle ,  Micha Kreibig ,  Thomas Scholl ,  Markus Dewes ,  Sven Brall

    IPC分类号： B01D35/00

    CPC分类号： B01D35/005 ,  B01D29/58 ,  B01D35/30 ,  B01D35/306 ,  B01D36/006 ,  B01D2201/295 ,  B01D2201/309 ,  B01D2201/34 ,  F02M37/22

    摘要： The invention relates to a filter device, in particular for fluids contaminated with water admixtures, such as diesel oil, comprising a filter housing (1), which can hold at least one filter element (9), the fiber medium (11) of which separates an untreated side (13) from a treated side (19) during the filtration process in the filter housing (1), wherein a water collecting unit (5) is provided, which holds separated water on the treated side, wherein said filter device is characterized in that water that has been separated on the untreated side (13) also reaches the collecting unit (5) and in that mutually separated collecting chambers (61, 67) are present in the collecting unit (5) for the water that is discharged both at the treated side (19) and at the untreated side (13).

    摘要翻译： 本发明涉及一种过滤装置，特别是对于被水混合物（例如柴油）污染的流体，该过滤装置包括可容纳至少一个过滤元件（9）的过滤器壳体（1），其中的纤维介质（11） 在过滤器壳体（1）的过滤过程中将未处理侧（13）与处理侧（19）分离，其中提供集水单元（5），其在处理侧保持分离的水，其中所述过滤装置 其特征在于，在未处理侧（13）上分离的水也到达收集单元（5），并且在收集单元（5）中存在相互分离的收集室（61,67） 在处理侧（19）和未处理侧（13）都排出。

    Enrichment of Low Molecular Weight DNA
    7.
    发明申请
    Enrichment of Low Molecular Weight DNA 审中-公开
    富集低分子量DNA

    公开(公告)号：US20120083597A1

    公开(公告)日：2012-04-05

    申请号：US13245265

    申请日：2011-09-26

    申请人： Patricia Okamoto ,  Jan Lawrence Godoski, JR. ,  Thomas Scholl

    发明人： Patricia Okamoto ,  Jan Lawrence Godoski, JR. ,  Thomas Scholl

    IPC分类号： C07H1/08

    CPC分类号： C12N15/1003

    摘要： The present invention provides, among other things, a simple, reproducible, and cost-effective method for enriching fetal or other low molecular weight nucleic acids in a biological sample. In certain embodiments, methods are provided for enriching fetal nucleic acids (e.g., fetal DNAs), typically comprising steps of adding a polymer such as PEG to a heterogeneous biological sample containing fetal DNA and high molecular weight non-fetal DNA such that the PEG precipitates substantially the high molecular weight non-fetal DNA, and purifying the fetal DNA from supernatant, thereby enriching the fetal DNA.

    摘要翻译： 本发明尤其提供了一种用于富集生物样品中的胎儿或其他低分子量核酸的简单，可重现和成本有效的方法。 在某些实施方案中，提供了用于富集胎儿核酸（例如胎儿DNA）的方法，通常包括将聚合物如PEG加入到含有胎儿DNA和高分子量非胎儿DNA的异质生物样品中的步骤，使得PEG沉淀 基本上是高分子量非胎儿DNA，并从上清液中纯化胎儿DNA，从而富集胎儿DNA。

    Identification of Differentially Represented Fetal or Maternal Genomic Regions and Uses Thereof
    8.
    发明申请
    Identification of Differentially Represented Fetal or Maternal Genomic Regions and Uses Thereof 审中-公开
    鉴别差异代谢胎儿或母体基因组区域及其用途

    公开(公告)号：US20120021919A1

    公开(公告)日：2012-01-26

    申请号：US13188794

    申请日：2011-07-22

    申请人： Thomas Scholl ,  Viatcheslav R. Akmaev

    发明人： Thomas Scholl ,  Viatcheslav R. Akmaev

    IPC分类号： C40B20/00 ,  C40B30/04 ,  G01N33/53 ,  C12Q1/68

    CPC分类号： C12Q1/6876 ,  C12Q2600/158

    摘要： The present invention provides a novel approach for identification and characterization of differentially represented fetal or maternal genomic regions in maternal circulation. Identification of overrepresented fetal genomic regions in the maternal circulation according to the present invention permit accurate analysis of fetal DNA without the need for enrichment or purification, which provides a simpler, more accurate and efficient prenatal diagnosis in early pregnancy. The present invention is particularly useful for noninvasive prenatal diagnosis during early pregnancy (e.g., during the first trimester).

    摘要翻译： 本发明提供了用于鉴别和表征母体循环中差异表达的胎儿或母体基因组区域的新方法。 根据本发明，在母体循环中代表过量的胎儿基因组区域的鉴定允许胎儿DNA的准确分析，而不需要富集或纯化，其在早期怀孕中提供更简单，更准确和有效的产前诊断。 本发明特别可用于早期怀孕期间的非侵入性产前诊断（例如，在妊娠前期）。

    APPARATUS FOR MEASURING BLOOD OXYGEN SATURATION
    9.
    发明申请
    APPARATUS FOR MEASURING BLOOD OXYGEN SATURATION 有权
    用于测量血氧饱和度的装置

    公开(公告)号：US20100279335A1

    公开(公告)日：2010-11-04

    申请号：US12742145

    申请日：2008-11-07

    申请人： Martin Eckermann ,  Thomas Scholl

    发明人： Martin Eckermann ,  Thomas Scholl

    IPC分类号： C12Q1/02 ,  C12M1/34 ,  B05D5/12

    CPC分类号： A61B5/6826 ,  A61B5/14552 ,  A61B5/6838 ,  A61B2562/222 ,  A61B2562/247

    摘要： The invention relates to an apparatus for measuring blood oxygen saturation, comprising a housing (1), a sensor (2), a connecting cable (3) and a plug (4), wherein the housing (1) has a cavity (5) for accepting a patient's tissue which is supplied with blood; the sensor (2) which is arranged on the housing and has at least one light source (21) for the emission of light which passes through the tissue which is supplied with blood and a detector (22) for receiving the light passing through the tissue which is supplied with blood; and the apparatus can be connected to an evaluation unit via the plug (4).

    摘要翻译： 本发明涉及一种用于测量血氧饱和度的装置，包括壳体（1），传感器（2），连接电缆（3）和插头（4），其中壳体（1）具有空腔（5） 用于接受供应血液的患者组织; 所述传感器（2）布置在所述壳体上并且具有至少一个光源（21），用于发射通过被供应血液的组织的光;以及检测器（22），用于接收穿过所述组织的光 供血; 并且该装置可以经由插头（4）连接到评估单元。

    Apparatus for improved pulse oximetry measurement
    10.
    发明授权
    Apparatus for improved pulse oximetry measurement 有权
    用于改善脉搏血氧饱和度测量的装置

    公开(公告)号：US07679519B2

    公开(公告)日：2010-03-16

    申请号：US11269524

    申请日：2005-11-07

    申请人： Bernd Lindner ,  Martin Eckermann ,  Thomas Scholl ,  Steven Gorski

    发明人： Bernd Lindner ,  Martin Eckermann ,  Thomas Scholl ,  Steven Gorski

    IPC分类号： G08B23/00

    CPC分类号： A61B5/14552 ,  A61B5/6826 ,  A61B5/6838 ,  G01N21/35 ,  G01N2021/3144

    摘要： An apparatus for measuring the blood oxygen level of a patient is disclosed. In one embodiment, the apparatus includes a housing having an interior surface of non-reflective material substantially surrounding an interior. A cooperating light source and detector are operatively positioned proximate the interior surface so as to emit and receive light projected within the interior of the housing. A material more conducive to light transmission, reflectance, or a combination thereof—as compared to the interior surface material—is positioned proximate the light source and/or detector.

    摘要翻译： 公开了一种用于测量患者的血氧水平的装置。 在一个实施例中，该装置包括壳体，其具有基本上围绕内部的非反射材料的内表面。 合作的光源和检测器可操作地定位在内表面附近，以便发射和接收投射在壳体内部的光。 与内表面材料相比，更有利于光透射，反射率或其组合的材料位于光源和/或检测器附近。