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公开(公告)号：US20090227949A1
公开(公告)日：2009-09-10
申请号：US12399548
申请日：2009-03-06
申请人： David Knapp , Timothy J. Mickley , John Chen , Derek Sutermeister , Toby Freyman , Gordon Kocur , Daniel Horn , Jim Anderson , Ben Arcand , Jay Rassat , Raed Rizq , Irina Nazarova , Dan Quillin , Jan Weber , Torsten Scheuermann
发明人： David Knapp , Timothy J. Mickley , John Chen , Derek Sutermeister , Toby Freyman , Gordon Kocur , Daniel Horn , Jim Anderson , Ben Arcand , Jay Rassat , Raed Rizq , Irina Nazarova , Dan Quillin , Jan Weber , Torsten Scheuermann
IPC分类号： A61M25/10
CPC分类号： A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/416 , A61M25/0045 , A61M25/10 , A61M2025/0056 , A61M2025/1031 , A61M2025/105 , B29L2009/005 , C08L53/02
摘要： Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. The balloon has one or more folds which serve as a reservoir for containing the therapeutic agent. The fold may have any of various configurations to hold the therapeutic agent. In some cases, the balloon comprises one or more lobes that forms the fold(s). The therapeutic agent may be provided in various ways. For example, the therapeutic agent may be contained in packets that rupture upon expansion of the balloon, or as a plurality of discrete bulk masses, or sealed within compartments.
摘要翻译： 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 气囊具有一个或多个折叠，其用作容纳治疗剂的储存器。 折叠可以具有保持治疗剂的各种构造中的任何一种。 在一些情况下，气囊包括形成褶皱的一个或多个凸起。 治疗剂可以以各种方式提供。 例如，治疗剂可以包含在囊膨胀时破裂的包装中，或者作为多个离散的体积块，或者密封在隔室内。
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公开(公告)号：US08114049B2
公开(公告)日：2012-02-14
申请号：US12399548
申请日：2009-03-06
申请人： Toby Freyman , Gordon Kocur , Daniel Horn
发明人： Toby Freyman , Gordon Kocur , Daniel Horn
CPC分类号： A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/416 , A61M25/0045 , A61M25/10 , A61M2025/0056 , A61M2025/1031 , A61M2025/105 , B29L2009/005 , C08L53/02
摘要： Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. The balloon has one or more folds which serve as a reservoir for containing the therapeutic agent. The fold may have any of various configurations to hold the therapeutic agent. In some cases, the balloon comprises one or more lobes that forms the fold(s). The therapeutic agent may be provided in various ways. For example, the therapeutic agent may be contained in packets that rupture upon expansion of the balloon, or as a plurality of discrete bulk masses, or sealed within compartments.
摘要翻译： 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 气囊具有一个或多个折叠，其用作容纳治疗剂的储存器。 折叠可以具有保持治疗剂的各种构造中的任何一种。 在一些情况下，气囊包括形成褶皱的一个或多个凸起。 治疗剂可以以各种方式提供。 例如，治疗剂可以包含在囊膨胀时破裂的包装中，或者作为多个离散的体积块，或者密封在隔室内。
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公开(公告)号：US20120053517A1
公开(公告)日：2012-03-01
申请号：US13289490
申请日：2011-11-04
申请人： John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
发明人： John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
IPC分类号： A61M25/10
CPC分类号： A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/416 , A61M25/0045 , A61M25/10 , A61M2025/0056 , A61M2025/1031 , A61M2025/105 , B29L2009/005 , C08L53/02
摘要： Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. In one aspect, one or more sheaths are disposed around the balloon with the therapeutic agent being disposed within the sheath, being disposed over the sheath, being contained in the space between the sheath and the balloon, or being otherwise associated with the sheath. In another aspect, the balloon includes a micro-electromechanical system (MEMS) for drug delivery.
摘要翻译： 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 在一个方面，一个或多个护套设置在球囊周围，治疗剂设置在护套内，设置在护套上，被包含在护套和气囊之间的空间中，或者与护套相关联。 另一方面，气囊包括用于药物递送的微机电系统（MEMS）。
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公开(公告)号：US20090227948A1
公开(公告)日：2009-09-10
申请号：US12399386
申请日：2009-03-06
申请人： John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
发明人： John Chen , Raed Rizq , Kent Harrison , Daniel Horn , Gordon Kocur , Tracee Eidenschink , Ben Arcand , Derek Sutermeister , Jay Rassat , Colm McGuiness , Wendy Naimark , Ruth Cheng
CPC分类号： A61M25/1029 , A61L29/085 , A61L29/16 , A61L2300/416 , A61M25/0045 , A61M25/10 , A61M2025/0056 , A61M2025/1031 , A61M2025/105 , B29L2009/005 , C08L53/02
摘要： Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. In one aspect, one or more sheaths are disposed around the balloon with the therapeutic agent being disposed within the sheath, being disposed over the sheath, being contained in the space between the sheath and the balloon, or being otherwise associated with the sheath. In another aspect, the balloon includes a micro-electromechanical system (MEMS) for drug delivery.
摘要翻译： 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 在一个方面，一个或多个护套设置在球囊周围，治疗剂设置在护套内，设置在护套上，被包含在护套和气囊之间的空间中，或者与护套相关联。 另一方面，气囊包括用于药物递送的微机电系统（MEMS）。
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公开(公告)号：US07335185B2
公开(公告)日：2008-02-26
申请号：US10622624
申请日：2003-07-18
申请人： Nie Tang , Daniel Horn
发明人： Nie Tang , Daniel Horn
IPC分类号： A61M29/00
CPC分类号： A61L29/085 , A61M25/1027 , A61M2025/1031 , A61M2025/1075
摘要： A dilatation balloon formed of a first material and further including at least one first plasma polymerized layer which forms the top most surface of the balloon, and a method of making the same.
摘要翻译： 由第一材料形成并且还包括形成气球最顶部表面的至少一个第一等离子体聚合层的膨胀球及其制造方法。
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公开(公告)号：US06863861B1
公开(公告)日：2005-03-08
申请号：US09672330
申请日：2000-09-28
IPC分类号： A61L29/00 , A61F2/958 , A61M25/00 , B29C49/08 , B29C49/22 , B29K67/00 , B29K77/00 , B29L31/00 , B29C47/00
CPC分类号： A61M25/1029
摘要： A balloon blowing process which involves radial expansion of an extruded tubing segment which has been subjected to a stretching step prior to radial expansion, the process utilizing an internal pressure and a temperature which together cause at least a portion of the tubing to expand to an interior diameter (ID) which is greater than the interior diameter of the extruded segment prior to extrusion.
摘要翻译： 一种气球吹制方法，其涉及在径向膨胀之前经受拉伸步骤的挤出管段的径向膨胀，所述方法利用内部压力和温度，其一起使至少一部分管道膨胀至内部 直径（ID）大于在挤出之前的挤压段的内径。
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公开(公告)号：US20050043679A1
公开(公告)日：2005-02-24
申请号：US10645055
申请日：2003-08-21
申请人： Douglas Devens , Daniel Horn
发明人： Douglas Devens , Daniel Horn
IPC分类号： A61F2/958 , A61M25/00 , A61M25/16 , B29C47/06 , B29C47/28 , B29C49/04 , B29C49/22 , A61M29/00
CPC分类号： B29C49/22 , A61M25/1002 , A61M25/1029 , A61M25/104 , A61M2025/1079 , B29C47/0023 , B29C47/0026 , B29C47/06 , B29C47/065 , B29C47/26 , B29C47/28 , B29C49/04 , B29C2049/228 , B29K2021/00 , B29K2023/083 , B29K2027/06 , B29K2055/02 , B29K2067/00 , B29K2067/006 , B29K2071/00 , B29K2075/00 , B29L2031/7542
摘要： Medical devices, such as medical balloons, and methods of making the devices, are disclosed. In some embodiments, the balloons include a portion, e.g., a layer, that varies in thickness.
摘要翻译： 公开了医疗装置，例如医用气囊，以及制造装置的方法。 在一些实施例中，气囊包括厚度变化的部分，例如层。
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公开(公告)号：US20080051760A1
公开(公告)日：2008-02-28
申请号：US11929208
申请日：2007-10-30
申请人： Victor Schoenle , Daniel Horn , Yiqun Wang , Lixiao Wang
发明人： Victor Schoenle , Daniel Horn , Yiqun Wang , Lixiao Wang
IPC分类号： A61M25/00
CPC分类号： A61M25/1036 , A61M25/0045 , A61M25/10 , A61M25/1006 , A61M2025/018 , Y10T29/49826 , Y10T29/49863 , Y10T29/49865 , Y10T428/13 , Y10T428/1334 , Y10T428/1345 , Y10T428/1352 , Y10T428/139 , Y10T428/1393
摘要： Medical device components, such as tube-shaped catheter components, are disclosed. In some embodiments, a medical device component includes a region that includes a polyamide having a post buckle fracture tensile strength of at least about 6500 psi.
摘要翻译： 公开了医疗装置部件，例如管状导管部件。 在一些实施例中，医疗装置部件包括包括具有至少约6500psi的后扣环断裂拉伸强度的聚酰胺的区域。
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公开(公告)号：US20060122560A1
公开(公告)日：2006-06-08
申请号：US11005734
申请日：2004-12-07
申请人： Robert Burgmeier , Daniel Horn
发明人： Robert Burgmeier , Daniel Horn
IPC分类号： C08J7/18
CPC分类号： C08J7/12 , A61L29/085 , A61L29/14 , C08J7/126 , C08J7/18
摘要： A medical device formed at least in part of a polymeric composition, and having a surface modified with covalently bonded fluorine, and a process for modifying the surface including the step of exposing the surface of the medical device to gaseous plasma sufficient to covalently bond fluorine to the surface.
摘要翻译： 至少部分由聚合物组合物形成并具有用共价键合的氟改性的表面的医疗装置，以及用于改变表面的方法，包括将医疗装置的表面暴露于气体等离子体的步骤，足以将氟共价键合到 表面。
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公开(公告)号：US20080051757A1
公开(公告)日：2008-02-28
申请号：US11929183
申请日：2007-10-30
申请人： Victor Schoenle , Daniel Horn , Yiqun Wang , Lixiao Wang
发明人： Victor Schoenle , Daniel Horn , Yiqun Wang , Lixiao Wang
IPC分类号： A61M31/00
CPC分类号： A61M25/1036 , A61M25/0045 , A61M25/10 , A61M25/1006 , A61M2025/018 , Y10T29/49826 , Y10T29/49863 , Y10T29/49865 , Y10T428/13 , Y10T428/1334 , Y10T428/1345 , Y10T428/1352 , Y10T428/139 , Y10T428/1393
摘要： Medical device components, such as tube-shaped catheter components, are disclosed. In some embodiments, a medical device component includes a region that includes a polyamide having a hoop stress ratio of at least about 1.25.
摘要翻译： 公开了医疗装置部件，例如管状导管部件。 在一些实施例中，医疗装置部件包括包括环向应力比为至少约1.25的聚酰胺的区域。
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