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    PROCESS FOR OBTAINING PECTIN
    1.
    发明申请
    PROCESS FOR OBTAINING PECTIN 审中-公开
    获取PECTIN的方法

    公开(公告)号：US20090110798A1

    公开(公告)日：2009-04-30

    申请号：US11908272

    申请日：2006-03-09

    申请人： Todd W. Gusek ,  Luca Zullo ,  Aharon M. Eyal

    发明人： Todd W. Gusek ,  Luca Zullo ,  Aharon M. Eyal

    IPC分类号： A23L1/0524 ,  C12P19/04 ,  C08B37/06

    CPC分类号： C12P19/04 ,  A23L2/06 ,  A23L2/62 ,  A23L27/13 ,  A23L29/231 ,  C08B37/0045

    摘要： There is described a method for obtaining pectin from a pectin-containing material that involves treating the pectin-containing material with an enzyme that causes the pectin to be released from the pectin-containing material. Suitable enzymes include, but are not limited to, cellulase enzymes, hemicellulase enzymes, and mixtures thereof. Ethanol and isopropanol are typical alcohols utilized in recovering the pectin. Also decarbohydrates scribed is the pectin produced by the method, and the use of the pectin in foods and beverages.

    摘要翻译： 描述了一种从含有果胶的材料中获得果胶的方法，该方法涉及用含有果胶的材料从果胶释放的酶处理含​​果胶物质。 合适的酶包括但不限于纤维素酶，半纤维素酶及其混合物。 乙醇和异丙醇是用于回收果胶的典型醇。 另外，划出的脱脂水合物是通过该方法生产的果胶，以及在食品和饮料中使用果胶。

    Production and recovery of organic acids
    5.
    发明授权
    Production and recovery of organic acids 失效
    生产和回收有机酸

    公开(公告)号：US5766439A

    公开(公告)日：1998-06-16

    申请号：US752803

    申请日：1996-11-20

    申请人： Aharon M. Eyal ,  William F. Lehnhardt

    发明人： Aharon M. Eyal ,  William F. Lehnhardt

    IPC分类号： C12P7/40 ,  C12P7/56 ,  C12P7/52 ,  C07C51/42 ,  C07C59/08 ,  C25B3/00

    CPC分类号： C12P7/56 ,  C12P7/40 ,  Y10S435/803

    摘要： A process is described for producing organic acids such as lactic acid. The process includes the steps of producing lactic acid by fermentation, resulting in an aqueous fermentation broth containing lactic acid, and adding a calcium base, such as calcium carbonate, to the fermentation broth, thereby producing calcium lactate in the broth. Biomass is removed from the broth, thereby leaving an aqueous solution or dispersion of calcium lactate. The calcium lactate is reacted with a source of ammonium ions, such as ammonium carbonate, or a mixture of ammonia and carbon dioxide, thereby producing an ammonium lactate. Contaminating cations can be removed by ion exchange. The free lactic acid or a derivative thereof can be separated from the ammonium ions, preferably by salt-splitting electrodialysis.

    摘要翻译： 描述了用于生产有机酸如乳酸的方法。 该方法包括通过发酵生产乳酸的步骤，得到含有乳酸的含水发酵液，并向发酵液中加入钙碱如碳酸钙，从而在肉汤中产生乳酸钙。 从肉汤中除去生物质，从而留下乳酸钙的水溶液或分散体。 将乳酸钙与铵离子源如碳酸铵或氨和二氧化碳的混合物反应，从而产生乳酸铵。 污染的阳离子可以通过离子交换去除。 游离乳酸或其衍生物可以与铵离子分离，优选通过盐分解电渗析。

    Citric acid extraction
    6.
    发明授权
    Citric acid extraction 失效
    柠檬酸提取

    公开(公告)号：US5426220A

    公开(公告)日：1995-06-20

    申请号：US271248

    申请日：1994-07-07

    申请人： Avraham M. Baniel ,  Aharon M. Eyal

    发明人： Avraham M. Baniel ,  Aharon M. Eyal

    IPC分类号： C07C51/48 ,  C07C51/42

    CPC分类号： C07C51/48

    摘要： In the production of citric acid aqueous mother liquor originating from a lime/sulfuric acid process is subjected to a multi-stage counter-current extraction with an amine based organic extractant. A solution of a further amount of citric acid derived from direct extraction of a citric acid fermentation broth is judicously injected into the organic phase stream in the counter-current extraction and a combined extract is withdrawn from the operation. This extract can be subjected to any known treatment for the recovery of citric acid values.

    摘要翻译： 在生产柠檬酸水性母液的过程中，使用胺类有机萃取剂进行多级逆流萃取。 将来自直接提取柠檬酸发酵液的更多量的柠檬酸的溶液在反向萃取中被司法注入有机相物流中，并从操作中取出合并的提取物。 该提取物可以进行任何已知的柠檬酸回收处理。

    Concurrent production of citric acid and alkali citrates
    7.
    发明授权
    Concurrent production of citric acid and alkali citrates 失效
    同时生产柠檬酸和柠檬酸碱

    公开(公告)号：US5231225A

    公开(公告)日：1993-07-27

    申请号：US946169

    申请日：1992-09-17

    申请人： Avraham M. Baniel ,  Aharon M. Eyal

    发明人： Avraham M. Baniel ,  Aharon M. Eyal

    IPC分类号： C01F11/18 ,  C07C51/41 ,  C07C51/48

    CPC分类号： C07C51/412 ,  C01F11/18 ,  C07C51/48

    摘要： The known liming sulfuric acid process for the recovery of crystalline citric acid from a fermentation broth is modified by subjecting the mother liquor from the crystallization to extraction with a water-immiscible organic extraction that contains an amine. The resulting extract is neutralized with a recycled brine with alkali citrate and alkali citrate is crystallized from the concentrated brine obtained this way.

    摘要翻译： 用于从发酵液中回收结晶柠檬酸的已知的柠檬酸硫酸方法是通过将来自结晶的母液用含有胺的水不混溶有机萃取进行萃取来改性的。 得到的提取物用碱性柠檬酸盐的再循环盐水中和，碱性柠檬酸盐从这样获得的浓缩盐水中结晶。

    Stable laquinimod preparations
    8.
    发明授权
    Stable laquinimod preparations 有权
    稳定的laquinimod制剂

    公开(公告)号：US08545885B2

    公开(公告)日：2013-10-01

    申请号：US13471175

    申请日：2012-05-14

    申请人： Muhammad Safadi ,  Daniella Licht ,  Ioana Lovinger ,  Aharon M. Eyal ,  Tomas Fristedt ,  Karl Jansson

    发明人： Muhammad Safadi ,  Daniella Licht ,  Ioana Lovinger ,  Aharon M. Eyal ,  Tomas Fristedt ,  Karl Jansson

    IPC分类号： A61K9/20

    CPC分类号： B65B25/00 ,  A61K9/1623 ,  A61K9/2004 ,  A61K9/2018 ,  A61K31/438 ,  A61K31/4704 ,  C07D209/34 ,  C07D209/42 ,  C07D471/10 ,  Y10T436/145555

    摘要： The subject invention provides a pharmaceutical composition comprising N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide or the salt thereof; a pharmaceutically acceptable carrier; and not more than 0.5% w/w relative to N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide of 2-Chloro-6-(1-ethyl-N-methyl-2-oxoindoline-3-carboxamido)benzoic acid, 1H,3H-spiro[5-chloro-1-methylquinoline-2,4-dione-3,3′-[1]ethylindolin-[2]-one], or 5-Chloro-N-ethyl-3-hydroxy-1-methyl-2,4-dioxo-N-phenyl-1,2,3,4-tetrahydro-quinoline-3-carboxamide.

    摘要翻译： 本发明提供了包含N-乙基-N-苯基-1,2-二氢-4-羟基-5-氯-1-甲基-2-氧代喹啉-3-甲酰胺或其盐的药物组合物; 药学上可接受的载体; 并且相对于2-氯 - 苯基-1,2-二氢-4-羟基-5-氯-1-甲基-2-氧代喹啉-3-甲酰胺，相对于N-乙基-N-苯基-1,2-二氢-4-羟基-5-氯-1-甲基-2-氧代喹啉-3-甲酰胺为0.5％w / 6-（1-乙基-N-甲基-2-氧代二氢吲哚-3-甲酰氨基）苯甲酸，1H，3H-螺[5-氯-1-甲基喹啉-2,4-二酮-3,3' - [1] 乙醛基 - [2] - 酮]或5-氯-N-乙基-3-羟基-1-甲基-2,4-二氧代-N-苯基-1,2,3,4-四氢 - 甲酰胺。