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1.发明授权Method for producing 1,5-pentamethylenediamine, 1,5-pentamethylenediamine, 1,5-pentamethylene diisocyanate, method for producing 1,5-pentamethylene diisocyanate, polyisocyanate composition, and polyurethane resin 有权1,5-戊二胺，1,5-戊二胺，1,5-五亚甲基二异氰酸酯的制造方法，1,5-五亚甲基二异氰酸酯的制造方法，多异氰酸酯组合物，聚氨酯树脂公开(公告)号：US09404132B2
公开(公告)日：2016-08-02
申请号：US13581554
申请日：2011-02-25
申请人： Tomonori Hidesaki , Akiko Natsuji , Toshihiko Nakagawa , Goro Kuwamura , Daisuke Hasegawa , Satoshi Yamasaki , Kuniaki Sato , Hiroshi Takeuchi
发明人： Tomonori Hidesaki , Akiko Natsuji , Toshihiko Nakagawa , Goro Kuwamura , Daisuke Hasegawa , Satoshi Yamasaki , Kuniaki Sato , Hiroshi Takeuchi
IPC分类号： C12P13/00 , C07C263/10 , C08G18/02 , C08G18/70 , C08G18/73 , C12N9/88 , C08G18/08 , C08G18/18 , C08G18/28 , C08G18/32 , C12N1/00
CPC分类号： C12P13/001 , C07C263/10 , C08G18/022 , C08G18/089 , C08G18/1875 , C08G18/283 , C08G18/3206 , C08G18/701 , C08G18/73 , C12N1/005 , C12N9/88 , Y02P20/52 , C07C265/14
摘要： In a method for producing 1,5-pentamethylenediamine, a lysine decarboxylase-expressing microorganism that is subjected to a treatment is used.
摘要翻译： 在制备1,5-戊二胺的方法中，使用表
达赖氨酸脱羧酶的微生物进行处理。-
2.发明申请METHOD FOR PRODUCING 1,5-PENTAMETHYLENEDIAMINE, 1,5-PENTAMETHYLENEDIAMINE, 1,5-PENTAMETHYLENE DIISOCYANATE, METHOD FOR PRODUCING 1,5-PENTAMETHYLENE DIISOCYANATE, POLYISOCYANATE COMPOSITION, AND POLYURETHANE RESIN 有权1,5-二戊烯二胺的制备方法，1,5-二戊烯二胺，1,5-戊二烯二异氰酸酯，1,1-二甲苯二异氰酸酯的制备方法，聚异氰酸酯组合物和聚氨酯树脂公开(公告)号：US20130079486A1
公开(公告)日：2013-03-28
申请号：US13581554
申请日：2011-02-25
申请人： Tomonori Hidesaki , Akiko Natsuji , Toshihiko Nakagawa , Goro Kuwamura , Daisuke Hasegawa , Satoshi Yamasaki , Kuniaki Sato , Hiroshi Takeuchi
发明人： Tomonori Hidesaki , Akiko Natsuji , Toshihiko Nakagawa , Goro Kuwamura , Daisuke Hasegawa , Satoshi Yamasaki , Kuniaki Sato , Hiroshi Takeuchi
IPC分类号： C12P13/00
CPC分类号： C12P13/001 , C07C263/10 , C08G18/022 , C08G18/089 , C08G18/1875 , C08G18/283 , C08G18/3206 , C08G18/701 , C08G18/73 , C12N1/005 , C12N9/88 , Y02P20/52 , C07C265/14
摘要： In a method for producing 1,5-pentamethylenediamine, a lysine decarboxylase-expressing microorganism that is subjected to a treatment is used.
摘要翻译： 在制备1,5-戊二胺的方法中，使用表
达赖氨酸脱羧酶的微生物进行处理。-
3.发明申请公开(公告)号：US20140363847A1
公开(公告)日：2014-12-11
申请号：US14235756
申请日：2012-07-27
申请人： Ryota Fujii , Tomokazu Shirai , Tadashi Araki , Koh Amano , Yoshiko Matsumoto , Toshihiro Tateno , Nozomi Takebayashi , Takashi Morishige , Hitoshi Takahashi , Mitsufumi Wada , Hiroshi Shimizu , Chikara Furusawa , Takashi Hirasawa , Tomonori Hidesaki , Ayako Endo , Dominik Lukas Jürgen-Lohmann , Anjali Madhavan
发明人： Ryota Fujii , Tomokazu Shirai , Tadashi Araki , Koh Amano , Yoshiko Matsumoto , Toshihiro Tateno , Nozomi Takebayashi , Takashi Morishige , Hitoshi Takahashi , Mitsufumi Wada , Hiroshi Shimizu , Chikara Furusawa , Takashi Hirasawa , Tomonori Hidesaki , Ayako Endo , Dominik Lukas Jürgen-Lohmann , Anjali Madhavan
CPC分类号： C12P19/40 , C12N1/20 , C12N9/0006 , C12N9/88 , C12N9/93 , C12P7/04 , C12P7/28 , C12P13/14 , C12P19/32 , C12Y101/0106 , C12Y101/01081 , C12Y401/01047 , C12Y401/03024 , C12Y602/01009
摘要： An acetyl-CoA-producing microorganism, which is capable of efficiently synthesizing acetyl-CoA using carbon dioxide, and a substance production method using the same are provided. An acetyl-CoA-producing microorganism including an acetyl-CoA production cycle obtained by imparting at least one type of enzymatic activity selected from the group consisting of malate thiokinase, malyl-CoA lyase, glyoxylate carboligase, 2-hydroxy-3-oxopropionate reductase, and hydroxypyruvate reductase, to a microorganism.
摘要翻译： 提供了能够使用二氧化碳有效地合成乙酰辅酶A的乙酰辅酶A产生微生物和使用其的物质制备方法。 一种乙酰辅酶A生产微生物，其包括通过赋予选自苹果酸硫激酶，丙烯酰辅酶A裂解酶，乙醛酸卡巴肼，2-羟基-3-氧代丙酸酯还原酶， 和羟丙酮酸还原酶。
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4.发明授权DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same 有权编码具有D-丝氨酸合成酶活性的新型酶的DNA，该酶的制造方法及使用该酶的方法生产D-丝氨酸公开(公告)号：US09212376B2
公开(公告)日：2015-12-15
申请号：US13034098
申请日：2011-02-24
申请人： Tadashi Araki , Tomonori Hidesaki , Seiichi Watanabe , Keita Nishida , Kiyoteru Nagahara , Mitsuo Koito
发明人： Tadashi Araki , Tomonori Hidesaki , Seiichi Watanabe , Keita Nishida , Kiyoteru Nagahara , Mitsuo Koito
CPC分类号： C12P13/06 , C12N9/1014
摘要： This invention relates to DNA encoding a novel enzyme having activity of synthesizing D-serine from formaldehyde and glycine, recombinant DNA constructed by integrating such DNA into a vector, a transformant transformed with the recombinant DNA, and a method for producing D-serine from formaldehyde and glycine with the use of the enzyme.
摘要翻译： 本发明涉及编码具有从甲醛和甘氨酸合成D-丝氨酸的新型酶的DNA，通过将这种DNA整合到载体中构建的重组DNA，用重组DNA转化的转化体和从甲醛生产D-丝氨酸的方法 和甘氨酸与酶的使用。
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公开(公告)号：US08895270B2
公开(公告)日：2014-11-25
申请号：US12681139
申请日：2008-09-30
申请人： Tomonori Hidesaki
发明人： Tomonori Hidesaki
IPC分类号： C12P13/22
CPC分类号： C12P13/222 , C12P13/225
摘要： Disclosed is a method for producing a β-amino acid comprising a step of synthesizing a β-amino acid from an α-amino acid in the presence of an amino acid aminomutase. In this method, a β-amino acid is precipitated as a solid in the reaction solution.
摘要翻译： 公开了一种生产β-氨基酸的方法，其包括在氨基酸氨基变位酶存在下从α-氨基酸合成β-氨基酸的步骤。 在该方法中，在反应溶液中以固体形式沉淀出氨基酸。
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6.发明授权DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same 有权编码具有D-丝氨酸合成酶活性的新型酶的DNA，该酶的制造方法及使用该酶的方法生产D-丝氨酸公开(公告)号：US07919285B2
公开(公告)日：2011-04-05
申请号：US11665194
申请日：2005-10-07
申请人： Tadashi Araki , Tomonori Hidesaki , Seiichi Watanabe , Keita Nishida , Kiyoteru Nagahara , Mitsuo Koito
发明人： Tadashi Araki , Tomonori Hidesaki , Seiichi Watanabe , Keita Nishida , Kiyoteru Nagahara , Mitsuo Koito
CPC分类号： C12P13/06 , C12N9/1014
摘要： This invention relates to DNA encoding an enzyme having activity of synthesizing D-serine from formaldehyde and glycine, recombinant DNA constructed by integrating such DNA into a vector, a transformant transformed with the recombinant DNA, and a method for producing D-serine from formaldehyde and glycine with the use of the enzyme.
摘要翻译： 本发明涉及编码具有从甲醛和甘氨酸合成D-丝氨酸的酶的酶的DNA，通过将这种DNA整合到载体中构建的重组DNA，用重组DNA转化的转化体和从甲醛生产D-丝氨酸的方法，以及 甘氨酸与酶的使用。
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7.发明申请Dna Encoding Novel Enzyme Having D-Serine Synthase Activity, Method of Producing the Enzyme and Method of Producing D-Serine by Using the Same 有权Dna编码具有D-丝氨酸合成酶活性的新型酶，生产酶的方法和使用该酶的方法生产D-丝氨酸公开(公告)号：US20080293098A1
公开(公告)日：2008-11-27
申请号：US11665194
申请日：2005-10-07
申请人： Tadashi Araki , Tomonori Hidesaki , Seiichi Watanabe , Keita Nishida , Kiyoteru Nagahara , Mitsuo Koito
发明人： Tadashi Araki , Tomonori Hidesaki , Seiichi Watanabe , Keita Nishida , Kiyoteru Nagahara , Mitsuo Koito
CPC分类号： C12P13/06 , C12N9/1014
摘要： This invention relates to DNA encoding a novel enzyme having activity of synthesizing D-serine from formaldehyde and glycine, recombinant DNA constructed by integrating such DNA into a vector, a transformant transformed with the recombinant DNA, and a method for producing D-serine from formaldehyde and glycine with the use of the enzyme.
摘要翻译： 本发明涉及编码具有从甲醛和甘氨酸合成D-丝氨酸的新型酶的DNA，通过将这种DNA整合到载体中构建的重组DNA，用重组DNA转化的转化体和从甲醛生产D-丝氨酸的方法 和甘氨酸与酶的使用。
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公开(公告)号：US09822387B2
公开(公告)日：2017-11-21
申请号：US14235756
申请日：2012-07-27
申请人： Ryota Fujii , Tomokazu Shirai , Tadashi Araki , Koh Amano , Yoshiko Matsumoto , Toshihiro Tateno , Nozomi Takebayashi , Takashi Morishige , Hitoshi Takahashi , Mitsufumi Wada , Hiroshi Shimizu , Chikara Furusawa , Takashi Hirasawa , Tomonori Hidesaki , Ayako Endo , Dominik Lukas Jürgen-Lohmann , Anjali Madhavan , Su Sun Chong
发明人： Ryota Fujii , Tomokazu Shirai , Tadashi Araki , Koh Amano , Yoshiko Matsumoto , Toshihiro Tateno , Nozomi Takebayashi , Takashi Morishige , Hitoshi Takahashi , Mitsufumi Wada , Hiroshi Shimizu , Chikara Furusawa , Takashi Hirasawa , Tomonori Hidesaki , Ayako Endo , Dominik Lukas Jürgen-Lohmann , Anjali Madhavan , Su Sun Chong
IPC分类号： C12N1/20 , C12N15/00 , C12N9/00 , C12N9/88 , C12N9/02 , C07H21/04 , C12P19/40 , C12P13/14 , C12N9/04 , C12P7/04 , C12P7/28 , C12P19/32
CPC分类号： C12P19/40 , C12N1/20 , C12N9/0006 , C12N9/88 , C12N9/93 , C12P7/04 , C12P7/28 , C12P13/14 , C12P19/32 , C12Y101/0106 , C12Y101/01081 , C12Y401/01047 , C12Y401/03024 , C12Y602/01009
摘要： An acetyl-CoA-producing microorganism, which is capable of efficiently synthesizing acetyl-CoA using carbon dioxide, and a substance production method using the same are provided. An acetyl-CoA-producing microorganism including an acetyl-CoA production cycle obtained by imparting at least one type of enzymatic activity selected from the group consisting of malate thiokinase, malyl-CoA lyase, glyoxylate carboligase, 2-hydroxy-3-oxopropionate reductase, and hydroxypyruvate reductase, to a microorganism.
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9.发明申请DNA ENCODING NOVEL ENZYME HAVING D-SERINE SYNTHASE ACTIVITY, METHOD OF PRODUCING THE ENZYME AND METHOD OF PRODUCING D-SERINE BY USING THE SAME 审中-公开编码具有D-丝氨酸合成酶活性的新型酶的DNA，生产酶的方法和使用该酶的方法生产D-丝氨酸公开(公告)号：US20120077233A1
公开(公告)日：2012-03-29
申请号：US13034098
申请日：2011-02-24
申请人： Tadashi Araki , Tomonori Hidesaki , Seiichi Watanabe , Keita Nishida , Kiyoteru Nagahara , Mitsuo Koito
发明人： Tadashi Araki , Tomonori Hidesaki , Seiichi Watanabe , Keita Nishida , Kiyoteru Nagahara , Mitsuo Koito
IPC分类号： C12P13/06
CPC分类号： C12P13/06 , C12N9/1014
摘要： This invention relates to DNA encoding a novel enzyme having activity of synthesizing D-serine from formaldehyde and glycine, recombinant DNA constructed by integrating such DNA into a vector, a transformant transformed with the recombinant DNA, and a method for producing D-serine from formaldehyde and glycine with the use of the enzyme.
摘要翻译： 本发明涉及编码具有从甲醛和甘氨酸合成D-丝氨酸的新型酶的DNA，通过将这种DNA整合到载体中构建的重组DNA，用重组DNA转化的转化体和从甲醛生产D-丝氨酸的方法 和甘氨酸与酶的使用。
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公开(公告)号：US20100221793A1
公开(公告)日：2010-09-02
申请号：US12681139
申请日：2008-09-30
申请人： Tomonori Hidesaki
发明人： Tomonori Hidesaki
CPC分类号： C12P13/222 , C12P13/225
摘要： Disclosed is a method for producing a β-amino acid comprising a step of synthesizing a β-amino acid from an α-amino acid in the presence of an amino acid aminomutase. In this method, a β-amino acid is precipitated as a solid in the reaction solution.
摘要翻译： 公开了一种生产β-氨基酸的方法，其包括在氨基酸氨基变位酶存在下从α-氨基酸合成β-氨基酸的步骤。 在该方法中，在反应溶液中以固体形式沉淀出氨基酸。
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