公开(公告)号：US07535411B2

公开(公告)日：2009-05-19

申请号：US11498333

申请日：2006-08-01

Applicant: Tony Falco

Inventor： Tony Falco

IPC: G01S7/40 ,  A61B19/00 ,  G01S13/06 ,  G01S13/88 ,  G01S13/00

CPC classification number: G01B21/042 ,  A61B34/20 ,  A61B2017/00725 ,  A61B2034/2055 ,  A61B2090/061 ,  A61B2090/0811 ,  G01B7/008 ,  G01B11/002 ,  G01B11/03 ,  G01B15/00 ,  G01B17/00

Abstract: A method and system for detecting drift in calibrated tracking systems used to locate features with respect to one or more coordinate systems allows medical devices to be accurately tracked within a reference coordinate system, and facilitates detection and compensation for changes in the orientation of the tracking system with respect to the coordinate system over time.

Abstract translation: 用于检测用于定位相对于一个或多个坐标系的特征的校准跟踪系统中的漂移的方法和系统允许在参考坐标系内精确地跟踪医疗设备，并且便于检测和补偿跟踪系统的取向的变化 相对于坐标系，随着时间的推移。

公开(公告)号：US20080064953A1

公开(公告)日：2008-03-13

申请号：US11852492

申请日：2007-09-10

Applicant: Tony Falco ,  Martin Lachaine ,  Jason Gorman

Inventor： Tony Falco ,  Martin Lachaine ,  Jason Gorman

IPC: A61B5/05

CPC classification number: A61B8/08 ,  A61B5/055 ,  A61B6/03 ,  A61B8/483 ,  A61N5/1049 ,  A61N2005/1058

Abstract: A diagnostic image of internal anatomical features of a patient is annotated with representations of external features, such both can be viewed together on a visual display. Adjustments to various treatment parameters relating to the administration of radiation therapy are provided, and the displayed image is automatically updated based on the adjustments.

Abstract translation: 用外部特征的表示注释患者的内部解剖特征的诊断图像，这两者可以在视觉显示器上一起观看。 提供了与放射治疗管理相关的各种治疗参数的调整，并根据调整自动更新显示的图像。

公开(公告)号：US20060036156A1

公开(公告)日：2006-02-16

申请号：US10894392

申请日：2004-07-19

Applicant: Martin Lachaine ,  Tony Falco

Inventor： Martin Lachaine ,  Tony Falco

IPC: A61B5/05

CPC classification number: A61N5/1049 ,  A61B6/04 ,  A61N2005/1061 ,  G06T7/38 ,  G06T7/74 ,  G06T2207/30004

Abstract: A displacement of a lesion within a patient is determined for the purpose of administering radiation treatment by generating sets of surface elements from three-dimensional images of the lesion taken at different times. Weights are assigned to the surface elements, and based on weights and the proximity of corresponding elements in one set to elements in another set, a displacement is determined.

Abstract translation: 为了通过从在不同时间拍摄的损伤的三维图像中产生一组表面元素来施加放射治疗的目的，确定患者内病变的位移。 权重被分配给表面元素，并且基于权重和一组中的相应元素与另一集合中的元素的接近度，确定位移。

公开(公告)号：US08000442B2

公开(公告)日：2011-08-16

申请号：US11184745

申请日：2005-07-19

Applicant: Martin Lachaine ,  Tony Falco ,  Véronique Audet ,  Xing Huang

Inventor： Martin Lachaine ,  Tony Falco ,  Véronique Audet ,  Xing Huang

IPC: A61N5/10

CPC classification number: G01S7/5205 ,  A61B8/00 ,  A61B8/4209 ,  A61B8/4245 ,  A61B8/587 ,  A61B2090/364 ,  G01S15/8936

Abstract: Methods and apparatus for calibrating images and imaging devices to common coordinate systems utilize, in some embodiments, rods that detectably reflect an acoustic signal regardless of the incidence angle of the signal with respect to the rods. Typically, the rods are disposed within a “phantom” at known positions with respect to a room coordinate system. Images of the cylindrical rods may be obtained from different directions, allowing the imaging device to be calibrated to the room coordinate system.

Abstract translation: 在一些实施例中，用于将图像和成像装置校准为公共坐标系的方法和装置在不管信号相对于杆的入射角如何的情况下利用可检测地反射声信号的杆。 通常，杆相对于房间坐标系在已知位置处设置在“体模”内。 可以从不同的方向获得圆柱形棒的图像，从而允许将成像装置校准到房间坐标系。

公开(公告)号：US20100099989A1

公开(公告)日：2010-04-22

申请号：US12647852

申请日：2009-12-28

Applicant: Tony Falco ,  Martin Lachaine

Inventor： Tony Falco ,  Martin Lachaine

IPC: A61B8/14

CPC classification number: G01S7/5206 ,  A61B8/0833 ,  A61B8/483 ,  A61N5/1048 ,  G01S7/52036 ,  G01S15/899

Abstract: Methods and systems for assessing the effects of therapy on a patient include obtaining baseline and treatment ultrasound scans of a treatment area of a patient where the treatment ultrasound scans are taken subsequent to the baseline scan and at various times during a course of radiotherapy treatment sessions. The baseline and treatment ultrasounds are compared, and as a result a damage map representing cell death within the treatment area can be constructed.

Abstract translation: 用于评估治疗对患者的影响的方法和系统包括获得患者治疗区域的基线和治疗超声扫描，其中在基线扫描之后和在放疗期间的不同时间进行治疗超声扫描。 比较基线和治疗超声波，结果可以构建表示治疗区域内细胞死亡的损伤图。

公开(公告)号：US20090275830A1

公开(公告)日：2009-11-05

申请号：US12479126

申请日：2009-06-05

Applicant: Tony Falco ,  Dimitre Hristov

Inventor： Tony Falco ,  Dimitre Hristov

IPC: A61B8/13 ,  G06K9/00

CPC classification number: A61N5/1049 ,  A61B8/08 ,  A61B8/4245 ,  A61N2005/105 ,  A61N2005/1051 ,  A61N2005/1058

Abstract: A method and apparatus for lesion or organ definition for the purpose of radiation treatment planning localization and treatment position verification. The apparatus uses a combination of an ultrasound imaging system and a diagnostic imaging system to acquire localization ultrasound images referenced in the coordinate space of the diagnostic imaging system through the use of position sensing system. The method compares the location of the lesion in the localization ultrasound images with the position of the lesion in ultrasound images taken while the patient lies on the treatment table of a therapy treatment unit, suggests corrective measures to place the lesion in its intended treatment position and executes the correction upon confirmation from qualified personnel.

Abstract translation: 用于放射治疗计划定位和治疗位置验证目的的病变或器官定义的方法和装置。 该装置使用超声成像系统和诊断成像系统的组合来通过使用位置感测系统来获取在诊断成像系统的坐标空间中参考的定位超声图像。 该方法比较了定位超声图像中的病变位置与患者位于治疗治疗单元治疗台上所拍摄的超声图像中的病变位置，提出了将病变置于其预期治疗位置的纠正措施， 从合格人员确认后执行更正。

公开(公告)号：US20060036170A1

公开(公告)日：2006-02-16

申请号：US11184745

申请日：2005-07-19

Applicant: Martin Lachaine ,  Tony Falco ,  Veronique Audet ,  Xing Huang

Inventor： Martin Lachaine ,  Tony Falco ,  Veronique Audet ,  Xing Huang

IPC: A61B8/00

CPC classification number: G01S7/5205 ,  A61B8/00 ,  A61B8/4209 ,  A61B8/4245 ,  A61B8/587 ,  A61B2090/364 ,  G01S15/8936

Abstract: Methods and apparatus for calibrating images and imaging devices to common coordinate systems utilize, in some embodiments, rods that detectably reflect an acoustic signal regardless of the incidence angle of the signal with respect to the rods. Typically, the rods are disposed within a “phantom” at known positions with respect to a room coordinate system. Images of the cylindrical rods may be obtained from different directions, allowing the imaging device to be calibrated to the room coordinate system.

Abstract translation: 在一些实施例中，用于将图像和成像装置校准为公共坐标系的方法和装置在不管信号相对于杆的入射角如何的情况下利用可检测地反射声信号的杆。 通常，杆相对于房间坐标系在已知位置处设置在“体模”内。 可以从不同的方向获得圆柱形棒的图像，从而允许将成像装置校准到房间坐标系。

公开(公告)号：US5686733A

公开(公告)日：1997-11-11

申请号：US625063

申请日：1996-03-29

Applicant: Biagio Gino Fallone ,  Tony Falco

Inventor： Biagio Gino Fallone ,  Tony Falco

IPC: A61B6/00 ,  A61N5/10 ,  G01T1/24

CPC classification number: A61N5/1049 ,  A61N2005/1054

Abstract: Megavoltage imaging method and apparatus are provided to monitor a target volume of a patient in real time. Structure and steps are provided for generating an image on a detector (having a layer of photoreceptor material deposited on a layer of a high density substrate) by passing a photon beam first through the target volume of the patient and subsequently through the detector. The layer of the high density substrate is on the side of incidence of the photon beam for intensifying photon quanta and filter-scattered radiation from the patient induced by the photon beam. Thus, the photons impinging on the high density substrate are converted to electrons, and the images generated by the electrons subsequently traversing the photoreceptor material to cause the target volume of the patient to be monitored in real time.

Abstract translation: 提供了Megavoltage成像方法和装置来实时监测患者的目标体积。 提供了结构和步骤，用于通过使光子束首先通过患者的目标体积并随后通过检测器在检测器上生成图像（具有沉积在高密度基底的层上的感光体材料层）。 高密度衬底的层位于光子束的入射侧，用于增强由光子束引起的患者的光子量子和滤波器散射的辐射。 因此，入射到高密度衬底上的光子被转换为电子，并且由电子产生的图像随后穿过光感受器材料以使得患者的目标体积被实时监测。

公开(公告)号：US10542962B2

公开(公告)日：2020-01-28

申请号：US12831546

申请日：2010-07-07

Applicant: Martin Lachaine ,  Sebastien Tremblay ,  Philippe Fortier ,  Sergei Koptenko ,  Tony Falco

Inventor： Martin Lachaine ,  Sebastien Tremblay ,  Philippe Fortier ,  Sergei Koptenko ,  Tony Falco

IPC: A61B8/00

Abstract: Radiation treatment is delivered to a patient by positioning the patient such that a radiation beam is delivered to a lesion within the patient along a beam-delivery path while securing a diagnostic imaging device about the patient such that the diagnostic imaging device does not intersect the beam-delivery path. Radiation therapy is simultaneously delivered along the beam-delivery path while diagnostic images are obtained using the imaging device.

公开(公告)号：US09248316B2

公开(公告)日：2016-02-02

申请号：US13239795

申请日：2011-09-22

Applicant: Martin Lachaine ,  Sebastien Tremblay ,  Fabienne Lathuiliere ,  Tony Falco

Inventor： Martin Lachaine ,  Sebastien Tremblay ,  Fabienne Lathuiliere ,  Tony Falco

IPC: A61B8/00 ,  A61N5/10 ,  A61B8/08 ,  A61B19/00 ,  G06T7/20

CPC classification number: A61N5/1049 ,  A61B8/085 ,  A61B8/4245 ,  A61B8/4263 ,  A61B8/4461 ,  A61B8/483 ,  A61B8/58 ,  A61B8/587 ,  A61B34/20 ,  A61B2034/2055 ,  A61B2034/2063 ,  A61B2034/2065 ,  A61B2090/378 ,  A61N2005/1058 ,  G06T7/248 ,  G06T2207/10132

Abstract: Various implementations of the invention provide techniques and supporting systems that facilitate real-time or near-real-time ultrasound tracking for the purpose of calculating changes in anatomical features during a medical procedure. More specifically, anatomical features within a patient undergoing a medical procedure are tracked by obtaining temporally-distinct three dimensional ultrasound images that include the feature of interest and obtaining a targeted subset of ultrasound images focused on the feature. Based on the targeted subset of ultrasound images, a displacement of the feature is determined and image parameters used to obtain the targeted subset of ultrasound images are adjusted based on the displacement. This results in a time-based sequence of three dimensional images and targeted ultrasound images of the feature that identify changes in the position, size, location, and/or shape of the feature.

Abstract translation: 本发明的各种实现提供了便于实时或近实时超声跟踪的技术和支持系统，以便在医疗过程期间计算解剖特征的变化。 更具体地，通过获得包括感兴趣特征的时间上不同的三维超声图像并获得集中在该特征上的超声图像的目标子集，跟踪经历医疗过程的患者内的解剖特征。 基于超声图像的目标子集，确定特征的位移，并且基于位移来调整用于获得超声图像的目标子集的图像参数。 这导致基于时间的三维图像序列和特征的目标超声图像，其识别特征的位置，大小，位置和/或形状的变化。