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1.发明申请公开(公告)号：US20060172336A1
公开(公告)日：2006-08-03
申请号：US11392505
申请日：2006-03-30
CPC分类号： B01L3/50273 , B01J2219/00274 , B01L3/502792 , B01L7/525 , B01L2200/0647 , B01L2300/0645 , B01L2300/089 , B01L2300/1827 , B01L2400/0415 , C12Q1/6813 , C12Q1/686 , G01N2035/00366 , G01N2035/00376 , C12Q2565/607 , C12Q2563/173 , C12Q2531/113 , C12Q2523/307
摘要： To provide a PCR method utilizing electrostatic transportation which allows separate control of individual DNA-containing droplets by accurately transporting the droplets, suitably controlling the temperature thereof and allowing a primer to react therewith; a hybridization method utilizing electrostatic transportation which allows rapid and easy detection of hybridization; and devices therefor. A biological sample (droplets containing DNA and primer) (9) is prepared in a chemically inert liquid layer (8), is electrostatically transported by the action of an electrostatic transportation plate (1) with electrostatic transportation electrodes (2) and is heated at a predetermined position of the electrostatic transportation plate (1), thus carrying out PCR.
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2.发明申请PCR and hybridization methods utilizing electrostatic transportation and devices therefor 审中-公开利用静电运输的PCR和杂交方法及其装置公开(公告)号：US20060166262A1
公开(公告)日：2006-07-27
申请号：US11392504
申请日：2006-03-30
CPC分类号： B01L3/50273 , B01J2219/00274 , B01L3/502792 , B01L7/525 , B01L2200/0647 , B01L2300/0645 , B01L2300/089 , B01L2300/1827 , B01L2400/0415 , C12Q1/6813 , C12Q1/686 , G01N2035/00366 , G01N2035/00376 , C12Q2565/607 , C12Q2563/173 , C12Q2531/113 , C12Q2523/307
摘要： To provide a PCR method utilizing electrostatic transportation which allows separate control of individual DNA-containing droplets by accurately transporting the droplets, suitably controlling the temperature thereof and allowing a primer to react therewith; a hybridization method utilizing electrostatic transportation which allows rapid and easy detection of hybridization; and devices therefor. A biological sample (droplets containing DNA and primer) (9) is prepared in a chemically inert liquid layer (8), is electrostatically transported by the action of an electrostatic transportation plate (1) with electrostatic transportation electrodes (2) and is heated at a predetermined position of the electrostatic transportation plate (1), thus carrying out PCR.
摘要翻译： 为了提供利用静电转移的PCR方法，其允许通过精确地输送液滴来单独控制含有DNA的液滴，适当地控制其温度并允许底漆与其反应; 利用静电运输的杂交方法，其允许快速和容易地检测杂交; 及其设备。 在化学惰性液体层（8）中制备生物样品（含有DNA和底漆的液滴）（9），通过静电输送板（1）的作用与静电输送电极（2）静电输送，并在 静电传输板（1）的预定位置，从而进行PCR。
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3.发明申请PCR and hybridization methods utilizing electrostatic transportation and devices therefor 审中-公开利用静电运输的PCR和杂交方法及其装置公开(公告)号：US20060166261A1
公开(公告)日：2006-07-27
申请号：US11392496
申请日：2006-03-30
CPC分类号： B01L3/50273 , B01J2219/00274 , B01L3/502792 , B01L7/525 , B01L2200/0647 , B01L2300/0645 , B01L2300/089 , B01L2300/1827 , B01L2400/0415 , C12Q1/6813 , C12Q1/686 , G01N2035/00366 , G01N2035/00376 , C12Q2565/607 , C12Q2563/173 , C12Q2531/113 , C12Q2523/307
摘要： To provide a PCR method utilizing electrostatic transportation which allows separate control of individual DNA-containing droplets by accurately transporting the droplets, suitably controlling the temperature thereof and allowing a primer to react therewith; a hybridization method utilizing electrostatic transportation which allows rapid and easy detection of hybridization; and devices therefor. A biological sample (droplets containing DNA and primer) (9) is prepared in a chemically inert liquid layer (8), is electrostatically transported by the action of an electrostatic transportation plate. (1) with electrostatic transportation electrodes (2) and is heated at a predetermined position of the electrostatic transportation plate (1), thus carrying out PCR.
摘要翻译： 为了提供利用静电转移的PCR方法，其允许通过精确地输送液滴来单独控制含有DNA的液滴，适当地控制其温度并允许底漆与其反应; 利用静电运输的杂交方法，其允许快速和容易地检测杂交; 及其设备。 在化学惰性液体层（8）中制备生物样品（含有DNA和底漆的液滴）（9），通过静电输送板的作用静电输送。 （1）用静电输送电极（2）进行加热，并在静电输送板（1）的规定位置加热，进行PCR。
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4.发明申请Pcr method by electrostatic transportation, hybridization method for electrostatic transportation and devices therefor 审中-公开静电运输的Pcr方法，静电运输的杂交方法及其装置公开(公告)号：US20050064423A1
公开(公告)日：2005-03-24
申请号：US10499827
申请日：2003-01-08
CPC分类号： B01L3/50273 , B01J2219/00274 , B01L3/502792 , B01L7/525 , B01L2200/0647 , B01L2300/0645 , B01L2300/089 , B01L2300/1827 , B01L2400/0415 , C12Q1/6813 , C12Q1/686 , G01N2035/00366 , G01N2035/00376 , C12Q2565/607 , C12Q2563/173 , C12Q2531/113 , C12Q2523/307
摘要： To provide a PCR method utilizing electrostatic transportation which allows separate control of individual DNA-containing droplets by accurately transporting the droplets, suitably controlling the temperature thereof and allowing a primer to react therewith; a hybridization method utilizing electrostatic transportation which allows rapid and easy detection of hybridization; and devices therefor. A biological sample (droplets containing DNA and primer) (9) is prepared in a chemically inert liquid layer (8), is electrostatically transported by the action of an electrostatic transportation plate (1) with electrostatic transportation electrodes (2) and is heated at a predetermined position of the electrostatic transportation plate (1), thus carrying out PCR.
摘要翻译： 为了提供利用静电转移的PCR方法，其允许通过精确地输送液滴来单独控制含有DNA的液滴，适当地控制其温度并允许底漆与其反应; 利用静电运输的杂交方法，其允许快速和容易地检测杂交; 及其设备。 在化学惰性液体层（8）中制备生物样品（含有DNA和底漆的液滴）（9），通过静电输送板（1）的作用与静电输送电极（2）静电输送，并在 静电传输板（1）的预定位置，从而进行PCR。
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公开(公告)号：US08883864B2
公开(公告)日：2014-11-11
申请号：US12826845
申请日：2010-06-30
CPC分类号： B01F13/0062 , B01F3/0807 , B01F3/0811 , B01F5/045 , B01F5/0471 , B01F13/0076 , B01F15/0201 , B01F15/0255 , B01F2003/0834 , B01F2003/0838 , B01F2215/0431 , B01J13/04 , B01J19/0093 , B01J2219/00783 , B01J2219/00853 , B01L3/5027 , Y10S366/04 , Y10S516/924 , Y10S516/927 , Y10T137/0329 , Y10T428/2984
摘要： A process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner is provided wherein a dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel in such a manner that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by the shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
摘要翻译： 提供一种用于以简单的方式快速生产乳液和微胶囊的方法和装置，其中将分散相从分散相进料口朝向在微通道中流动的连续相喷射，使得分散相和 连续相交叉，从而获得由连续相的剪切力形成的微滴，其尺寸小于用于进料分散相的通道的宽度。
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公开(公告)号：US20060079584A1
公开(公告)日：2006-04-13
申请号：US11287252
申请日：2005-11-28
CPC分类号： B01F13/0062 , B01F3/0807 , B01F3/0811 , B01F5/045 , B01F5/0471 , B01F13/0076 , B01F15/0201 , B01F15/0255 , B01F2003/0834 , B01F2003/0838 , B01F2215/0431 , B01J13/04 , B01J19/0093 , B01J2219/00783 , B01J2219/00853 , B01L3/5027 , Y10S366/04 , Y10S516/924 , Y10S516/927 , Y10T137/0329 , Y10T428/2984
摘要： A process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner is provided wherein a dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel in such a manner that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by the shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
摘要翻译： 提供一种用于以简单的方式快速生产乳液和微胶囊的方法和装置，其中将分散相从分散相进料口朝向在微通道中流动的连续相喷射，使得分散相和 连续相交叉，从而获得由连续相的剪切力形成的微滴，其尺寸小于用于进料分散相的通道的宽度。
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公开(公告)号：US20060077755A1
公开(公告)日：2006-04-13
申请号：US11287253
申请日：2005-11-28
CPC分类号： B01F13/0062 , B01F3/0807 , B01F3/0811 , B01F5/045 , B01F5/0471 , B01F13/0076 , B01F15/0201 , B01F15/0255 , B01F2003/0834 , B01F2003/0838 , B01F2215/0431 , B01J13/04 , B01J19/0093 , B01J2219/00783 , B01J2219/00853 , B01L3/5027 , Y10S366/04 , Y10S516/924 , Y10S516/927 , Y10T137/0329 , Y10T428/2984
摘要： The present invention provides a process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner. A dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel in such a manner that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by the shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
摘要翻译： 本发明提供了一种以简单的方式快速生产乳液和微胶囊的方法和装置。 将分散相从分散相进料口朝着在微通道中流动的连续相流出，使得分散相和连续相的流动相互交叉，由此获得由连续的剪切力形成的微滴 相位，其尺寸小于用于馈送分散相的通道的宽度。
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公开(公告)号：US07268167B2
公开(公告)日：2007-09-11
申请号：US10468015
申请日：2002-02-13
CPC分类号： B01F13/0062 , B01F3/0807 , B01F3/0811 , B01F5/045 , B01F5/0471 , B01F13/0076 , B01F15/0201 , B01F15/0255 , B01F2003/0834 , B01F2003/0838 , B01F2215/0431 , B01J13/04 , B01J19/0093 , B01J2219/00783 , B01J2219/00853 , B01L3/5027 , Y10S366/04 , Y10S516/924 , Y10S516/927 , Y10T137/0329 , Y10T428/2984
摘要： A process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner. A dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel such that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by the shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
摘要翻译： 用于以简单的方式快速生产乳液和微胶囊的方法和装置。 分散相从分散相进料口朝着在微通道中流动的连续相排出，使得分散相和连续相的流动彼此交叉，从而获得通过连续相的剪切力形成的微滴，其具有由连续相的剪切力形成的微滴， 尺寸小于用于供给分散相的通道的宽度。
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公开(公告)号：US07717615B2
公开(公告)日：2010-05-18
申请号：US11287253
申请日：2005-11-28
IPC分类号： B01F5/00
CPC分类号： B01F13/0062 , B01F3/0807 , B01F3/0811 , B01F5/045 , B01F5/0471 , B01F13/0076 , B01F15/0201 , B01F15/0255 , B01F2003/0834 , B01F2003/0838 , B01F2215/0431 , B01J13/04 , B01J19/0093 , B01J2219/00783 , B01J2219/00853 , B01L3/5027 , Y10S366/04 , Y10S516/924 , Y10S516/927 , Y10T137/0329 , Y10T428/2984
摘要： In a process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner, a dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel in such a manner that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by a shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
摘要翻译： 在用于以简单的方式快速生产乳液和微胶囊的方法和装置中，将分散相从分散相进料口喷射到在微通道中流动的连续相，使得分散相和连续的 相位交叉，从而获得由连续相的剪切力形成的微滴，其尺寸小于用于进料分散相的通道的宽度。
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公开(公告)号：US20060079583A1
公开(公告)日：2006-04-13
申请号：US11287251
申请日：2005-11-28
CPC分类号： B01F13/0062 , B01F3/0807 , B01F3/0811 , B01F5/045 , B01F5/0471 , B01F13/0076 , B01F15/0201 , B01F15/0255 , B01F2003/0834 , B01F2003/0838 , B01F2215/0431 , B01J13/04 , B01J19/0093 , B01J2219/00783 , B01J2219/00853 , B01L3/5027 , Y10S366/04 , Y10S516/924 , Y10S516/927 , Y10T137/0329 , Y10T428/2984
摘要： A process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner is provided wherein a dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel in such a manner that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by the shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
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