摘要:
An implantable medical device can include an electrode substrate electrically connected to at least one electrode. The device can have a pseudoporous surface across the electrode substrate and electrode. This surface can result in a real surface area (RSA) greater than the geometric surface area (GSA) of the device. The pseudoporous surface can be a macroporous surface enabling a charge injection capacity greater than 1 mC/cm2 while minimizing rejection of the device by surrounding tissue in chronic implant applications. The electrode can be a thin layer of conductive material, such as platinum or another metal, conformally deposited on the pseudoporous surface of the electrode substrate. A method of making the implantable device can include forming the device having an electrode substrate and at least one electrode electrically coupled to the electrode substrate, and forming a pseudoporous surface on the electrode substrate and electrode.
摘要:
A multi-site electrode array (100) can include a microneedle array and a set of electrically active sites (115). The microneedle array includes a plurality of microneedles (105) supported on a base substrate (110). The set of electrically active sites (115) can be arranged at and/or near the tip of each microneedle (105), and in many cases along a shaft of the microneedles. Further, at least a portion of the active sites (115) can be independently electrically addressable such that a remaining portion of the active sites (115) are optionally electrically shunted together. In some cases all of the active sites (115) are independently electrically addressable
摘要:
Technology for a neural interface is described. The neural interface can include an intracranial electrode grid operable to detect neural activity. The neural interface can include a subcutaneous microelectronic signal processing unit operable to process the neural activity in order to obtain digital neural activity information. The neural interface can include a cable connecting the intracranial electrode grid and the subcutaneous microelectronic signal processing unit. The neural interface can include a wired connector attached to the subcutaneous microelectronic signal processing unit that is operable to transmit the digital neural activity information from the subcutaneous microelectronic signal processing unit to an external signal processing device.
摘要:
The present disclosure provides systems and methods related to electroencephalography (EEG) electrode arrays. In particular, the present disclosure provides systems and methods relating to the manufacture and use of high-resolution electrocorticography (ECOG) electrode arrays and stereoelectroencephalography (SEEG) electrode arrays having various combinations and arrangements of microelectrodes and macroelectrodes for recording and modulating nervous system activity.
摘要:
A high aspect ratio shadow mask and a method of making and using the high aspect ratio shadow mask can provide multiple conductive trace pathways along high aspect ratio electrodes. The high aspect ratio shadow mask can include a substantially planar base layer and a plurality of hollow high aspect ratio projections extending from the substantially planar base layer. The high aspect ratio shadow mask can further include a plurality of openings along the hollow projections which define trace deposition patterns.
摘要:
An implantable medical device can include an electrode substrate electrically connected to at least one electrode. The device can have a pseudoporous surface across the electrode substrate and electrode. This surface can result in a real surface area (RSA) greater than the geometric surface area (GSA) of the device. The pseudoporous surface can be a macroporous surface enabling a charge injection capacity greater than 1 mC/cm2 while minimizing rejection of the device by surrounding tissue in chronic implant applications. The electrode can be a thin layer of conductive material, such as platinum or another metal, conformally deposited on the pseudoporous surface of the electrode substrate. A method of making the implantable device can include forming the device having an electrode substrate and at least one electrode electrically coupled to the electrode substrate, and forming a pseudoporous surface on the electrode substrate and electrode.
摘要翻译:可植入医疗装置可以包括电连接到至少一个电极的电极基底。 器件可以在电极基底和电极上具有伪孔表面。 该表面可以导致大于装置的几何表面积(GSA)的实际表面积(RSA)。 伪孔表面可以是大孔表面,使得电荷注入能力大于1mC / cm 2,同时通过在慢性植入物应用中的周围组织最小化装置的排斥。 电极可以是保形地沉积在电极基板的伪孔表面上的导电材料的诸如铂或另一种金属的薄层。 制造可植入装置的方法可以包括形成具有电极基板的装置和与电极基板电耦合的至少一个电极,以及在电极基板和电极上形成伪孔表面。
摘要:
A method of manufacturing a micro-molded electrode (160) having multiple individually addressable sensors (140) along a shaft (180) can include forming a recess in a mold substrate, depositing a structural material therein, depositing a conductive material at specific locations, providing a coating (190), and removing the mold substrate. A micro-molded electrode (160) having a base (170) tapering to at least one shaft (180) can include an electrode substrate, multiple individually addressable sensors (140), and a coating (190).
摘要:
A high aspect ratio shadow mask and a method of making and using the high aspect ratio shadow mask can provide multiple conductive trace pathways along high aspect ratio electrodes. The high aspect ratio shadow mask can include a substantially planar base layer and a plurality of hollow high aspect ratio projections extending from the substantially planar base layer. The high aspect ratio shadow mask can further include a plurality of openings along the hollow projections which define trace deposition patterns.
摘要:
Technology for a neural interface is described. The neural interface can include an intracranial electrode grid operable to detect neural activity. The neural interface can include a subcutaneous microelectronic signal processing unit operable to process the neural activity in order to obtain digital neural activity information. The neural interface can include a cable connecting the intracranial electrode grid and the subcutaneous microelectronic signal processing unit. The neural interface can include a wired connector attached to the subcutaneous microelectronic signal processing unit that is operable to transmit the digital neural activity information from the subcutaneous microelectronic signal processing unit to an external signal processing device.
摘要:
A method of manufacturing a micro-molded electrode having multiple individually addressable sensors along a shaft can include forming a recess in a mold substrate, depositing a structural material therein, depositing a conductive material at specific locations, providing a coating, and removing the mold substrate. A micro-molded electrode having a base tapering to at least one shaft can include an electrode substrate, multiple individually addressable sensors, and a coating.