公开(公告)号：US10039562B2

公开(公告)日：2018-08-07

申请号：US15452590

申请日：2017-03-07

Applicant: University of Washington through its Center for Commercialization

Inventor： Michael Bailey ,  Bryan Cunitz ,  Barbrina Dunmire

IPC: A61B17/225 ,  A61B6/03 ,  A61B6/00 ,  A61B8/08 ,  G01S7/52 ,  G01S15/89 ,  A61B5/00 ,  A61N7/00 ,  A61B5/055 ,  A61B90/00 ,  A61B17/22

Abstract: Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.

公开(公告)号：US20170273699A1

公开(公告)日：2017-09-28

申请号：US15452590

申请日：2017-03-07

Applicant: University of Washington through its Center for Commercialization

Inventor： Michael Bailey ,  Bryan Cunitz ,  Barbrina Dunmire

IPC: A61B17/225

CPC classification number: A61B17/225 ,  A61B5/055 ,  A61B5/7232 ,  A61B6/03 ,  A61B6/485 ,  A61B8/085 ,  A61B8/488 ,  A61B17/2256 ,  A61B2017/22005 ,  A61B2090/378 ,  A61N7/00 ,  A61N2007/0004 ,  A61N2007/0052 ,  A61N2007/0082 ,  G01S7/52071 ,  G01S15/899

Abstract: Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.

公开(公告)号：US09414806B2

公开(公告)日：2016-08-16

申请号：US14079874

申请日：2013-11-14

Applicant: University of Washington Through Its Center for Commercialization ,  University of British Columbia

Inventor： Michael Bailey ,  Joel Teichman ,  Mathew Sorensen

IPC: A61B8/08 ,  A61B8/12 ,  A61B5/107 ,  A61B17/225 ,  A61B1/307 ,  A61B17/22

CPC classification number: A61B8/12 ,  A61B1/307 ,  A61B5/1076 ,  A61B8/08 ,  A61B8/5215 ,  A61B17/22012 ,  A61B17/2256 ,  A61B2090/061

Abstract: A transducer is used to send an ultrasound pulse toward a stone and to receive ultrasound reflections from the stone. The recorded time between a pulse that is reflected from the proximal surface and a pulse that is reflected either from the distal surface of the stone or from a surface supporting the stone is used to calculate the stone size. The size of the stone is a function of the time between the two pulses and the speed of sound through the stone (or through the surrounding fluid if the second pulse was reflected by the surface supporting the stone). This technique is equally applicable to measure the size of other in vivo objects, including soft tissue masses, cysts, uterine fibroids, tumors, and polyps.

公开(公告)号：US20160082291A1

公开(公告)日：2016-03-24

申请号：US14941276

申请日：2015-11-13

Applicant: University of Washington through its Center for Commercialization

Inventor： Michael Bailey ,  John Kucewicz ,  Barbrina Dunmire ,  Neil Owen ,  Bryan Cunitz

IPC: A61N7/00

CPC classification number: A61B17/225 ,  A61B5/055 ,  A61B5/7232 ,  A61B6/03 ,  A61B6/485 ,  A61B8/085 ,  A61B8/488 ,  A61B17/2256 ,  A61B2017/22005 ,  A61B2090/378 ,  A61N7/00 ,  A61N2007/0004 ,  A61N2007/0052 ,  A61N2007/0082 ,  G01S7/52071 ,  G01S15/899

Abstract: Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.

Abstract translation: 这里描述了用于通过超声检测石块的方法和装置，其中相对于来自血液或组织的超声波反射优先选择和加强来自石头的超声反射。 本文还描述了将推进超声应用于体内石块或其它物体的方法和装置，以便于去除这样的体内物体。

公开(公告)号：US20160113667A1

公开(公告)日：2016-04-28

申请号：US14928440

申请日：2015-10-30

Applicant: University of Washington through its Center for Commercialization

Inventor： Michael Bailey ,  Bryan Cunitz ,  Barbrina Dunmire

IPC: A61B17/225 ,  A61B6/00 ,  A61B6/03 ,  A61B8/08

CPC classification number: A61B17/225 ,  A61B5/055 ,  A61B5/7232 ,  A61B6/03 ,  A61B6/485 ,  A61B8/085 ,  A61B8/488 ,  A61B17/2256 ,  A61B2017/22005 ,  A61B2090/378 ,  A61N7/00 ,  A61N2007/0004 ,  A61N2007/0052 ,  A61N2007/0082 ,  G01S7/52071 ,  G01S15/899

Abstract: Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.

公开(公告)号：US10426499B2

公开(公告)日：2019-10-01

申请号：US13966535

申请日：2013-08-14

Applicant: University of Washington Through Its Center for Commercialization

Inventor： Neil Owen ,  Michael Bailey ,  Oleg Sapozhinikov

IPC: A61B17/22 ,  A61B7/00 ,  G06T7/00 ,  A61B17/225 ,  G10K11/35 ,  A61B8/08 ,  A61N7/02 ,  A61B5/05 ,  A61B5/06 ,  A61B8/00 ,  A61B5/00 ,  A61B7/04 ,  A61B8/13 ,  A61N7/00 ,  G10K15/04

Abstract: During shock wave therapy, a determination is made that a kidney stone has begun to fracture, and then a progress of its fragmentation is assessed. This determination can reduce the number of shock waves used to disintegrate kidney stones, and thereby reduce dose-dependent tissue damage. The identification of fracture is possible through the detection and analysis of resonant acoustic scattering, which is the radiation caused by reverberations within a stone particle that is struck by a shock wave. The scattering frequency can provide both an indication that the kidney stone has fragmented, and an indication of the relative sizes of the fragments. Related concepts employ displacement measurements of kidney stones/fragments to provide both an indication that the kidney stone has fragmented, and an indication of the relative sizes of the fragments. Such techniques can be combined with vibro-acoustography based gating that better targets the stone.

公开(公告)号：US10350439B2

公开(公告)日：2019-07-16

申请号：US14777949

申请日：2014-03-28

Applicant: University of Washington through its Center for Commercialization ,  The Trustees of Columbia University in the City of New York

Inventor： Adam Maxwell ,  Ryan Hsi ,  Thomas Lendvay ,  Pasquale Casale ,  Michael Bailey

IPC: A61N7/00 ,  A61B8/00 ,  A61B8/08 ,  A61N7/02 ,  A61B90/00

Abstract: Methods for diagnosing a pathologic tissue membrane, as well as a focused ultrasound apparatus and methods of treatment are disclosed to perform ureterocele puncture noninvasively using focused ultrasound-generated cavitation or boiling bubbles to controllably erode a hole through the tissue. An example ultrasound apparatus may include (a) a therapy transducer having a treatment surface, wherein the therapy transducer comprises a plurality of electrically isolated sections, (b) at least one concave acoustic lens defining a therapy aperture in the treatment surface of the therapy transducer, (c) an imaging aperture defined by either the treatment surface of the therapy transducer or by the at least one concave acoustic lens and (d) an ultrasound imaging probe axially aligned with a central axis of the therapy aperture.

公开(公告)号：US09597102B2

公开(公告)日：2017-03-21

申请号：US14928440

申请日：2015-10-30

Applicant: University of Washington through its Center for Commercialization

Inventor： Michael Bailey ,  Bryan Cunitz ,  Barbrina Dunmire

IPC: A61B5/05 ,  A61B17/225 ,  A61B8/08 ,  A61N7/00 ,  A61B6/03 ,  A61B6/00 ,  A61B5/055 ,  A61B17/22 ,  G01S7/52 ,  G01S15/89 ,  A61B5/00

CPC classification number: A61B17/225 ,  A61B5/055 ,  A61B5/7232 ,  A61B6/03 ,  A61B6/485 ,  A61B8/085 ,  A61B8/488 ,  A61B17/2256 ,  A61B2017/22005 ,  A61B2090/378 ,  A61N7/00 ,  A61N2007/0004 ,  A61N2007/0052 ,  A61N2007/0082 ,  G01S7/52071 ,  G01S15/899

Abstract: Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.

公开(公告)号：US20140194737A1

公开(公告)日：2014-07-10

申请号：US14079874

申请日：2013-11-14

Applicant: University of British Columbia ,  University of Washington Through Its Center for Commercialization

Inventor： Michael Bailey ,  Joel Teichman ,  Mathew Sorensen

IPC: A61B8/12 ,  A61B8/08 ,  A61B5/107

CPC classification number: A61B8/12 ,  A61B1/307 ,  A61B5/1076 ,  A61B8/08 ,  A61B8/5215 ,  A61B17/22012 ,  A61B17/2256 ,  A61B2090/061

Abstract: A transducer is used to send an ultrasound pulse toward a stone and to receive ultrasound reflections from the stone. The recorded time between a pulse that is reflected from the proximal surface and a pulse that is reflected either from the distal surface of the stone or from a surface supporting the stone is used to calculate the stone size. The size of the stone is a function of the time between the two pulses and the speed of sound through the stone (or through the surrounding fluid if the second pulse was reflected by the surface supporting the stone). This technique is equally applicable to measure the size of other in vivo objects, including soft tissue masses, cysts, uterine fibroids, tumors, and polyps.

Abstract translation: 传感器用于向石头发送超声脉冲并从石头接收超声反射。 从近端表面反射的脉冲与从石头的远端表面或从支撑石头的表面反射的脉冲之间的记录时间用于计算石头尺寸。 石头的大小是两个脉冲之间的时间和通过石头的声音的速度（或者如果第二个脉冲被支撑石头的表面反射的话，通过周围的流体）的函数。 该技术同样适用于测量其他体内物体的大小，包括软组织块，囊肿，子宫肌瘤，肿瘤和息肉。

公开(公告)号：US20200078608A1

公开(公告)日：2020-03-12

申请号：US16447771

申请日：2019-06-20

Applicant: University of Washington through its Center for Commercialization ,  The Trustees of Columbia University in the City of New York

Inventor： Adam Maxwell ,  Ryan Hsi ,  Thomas Lendvay ,  Pasquale Casale ,  Michael Bailey

IPC: A61N7/00 ,  A61B8/08 ,  A61N7/02 ,  A61B8/00

Abstract: Methods for diagnosing a pathologic tissue membrane, as well as a focused ultrasound apparatus and methods of treatment are disclosed to perform ureterocele puncture noninvasively using focused ultrasound-generated cavitation or boiling bubbles to controllably erode a hole through the tissue. An example ultrasound apparatus may include (a) a therapy transducer having a treatment surface, wherein the therapy transducer comprises a plurality of electrically isolated sections, (b) at least one concave acoustic lens defining a therapy aperture in the treatment surface of the therapy transducer, (c) an imaging aperture defined by either the treatment surface of the therapy transducer or by the at least one concave acoustic lens and (d) an ultrasound imaging probe axially aligned with a central axis of the therapy aperture.