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    Lateral Flow Immunoassay Controls
    2.
    发明申请
    Lateral Flow Immunoassay Controls 有权
    侧流免疫测定控制

    公开(公告)号：US20120237923A1

    公开(公告)日：2012-09-20

    申请号：US13481599

    申请日：2012-05-25

    申请人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

    发明人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

    IPC分类号： G01N21/78 ,  C12Q1/04 ,  G01N33/566 ,  C12Q1/70

    CPC分类号： G01N33/521 ,  Y10S436/808 ,  Y10S436/81

    摘要： Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read.

    摘要翻译： 快速侧流免疫测定在临床和家庭环境中具有广泛的应用历史。 这些装置用于测试各种分析物，例如滥用药物，激素，蛋白质，尿液或血浆成分等。 本发明提供了一种改进的程序控制，其向测试用户指示所应用样品的至少一部分已经通过测试条的测试结果区域，并且可选地，测试完成并且可以读取测试结果。

    Water-soluble conjugates and methods of preparation
    4.
    发明申请
    Water-soluble conjugates and methods of preparation 审中-公开
    水溶性偶联物及其制备方法

    公开(公告)号：US20060040258A1

    公开(公告)日：2006-02-23

    申请号：US10924738

    申请日：2004-08-23

    申请人： Huiyan Guo ,  Lorraine Bautista ,  Zurong Wu ,  Jinn-nan Lin

    发明人： Huiyan Guo ,  Lorraine Bautista ,  Zurong Wu ,  Jinn-nan Lin

    IPC分类号： C12Q1/70 ,  G01N33/53 ,  G01N33/554 ,  G01N33/569

    CPC分类号： G01N33/532

    摘要： The present invention provides water-soluble conjugates and methods of using them in diagnostic and detection assays. Devices for performing detection and quantitation assays are also provided. In various embodiments the conjugates are useful in immunoassays and later flow assays. The invention also provides methods of preparing the conjugates that result in higher yields and higher sensitivities for the assays.

    摘要翻译： 本发明提供水溶性缀合物及其在诊断和检测测定中的使用方法。 还提供了用于进行检测和定量测定的装置。 在各种实施方案中，缀合物可用于免疫测定和随后的流式测定。 本发明还提供了制备结合物的方法，其导致更高的产率和更高的敏感性。

    Lateral flow immunoassay controls
    5.
    发明授权
    Lateral flow immunoassay controls 有权
    侧流免疫测定对照

    公开(公告)号：US08828739B2

    公开(公告)日：2014-09-09

    申请号：US13481599

    申请日：2012-05-25

    申请人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

    发明人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

    IPC分类号： G01N33/53 ,  G01N33/52

    CPC分类号： G01N33/521 ,  Y10S436/808 ,  Y10S436/81

    摘要： Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read.

    摘要翻译： 快速侧流免疫测定在临床和家庭环境中具有广泛的应用历史。 这些装置用于测试各种分析物，例如滥用药物，激素，蛋白质，尿液或血浆成分等。 本发明提供了一种改进的程序控制，其向测试用户指示所应用样品的至少一部分已经通过测试条的测试结果区域，并且可选地，测试完成并且可以读取测试结果。

    Sanitary fluid collection, application and storage device and methods of use of same
    6.
    发明申请
    Sanitary fluid collection, application and storage device and methods of use of same 审中-公开
    卫生液体采集，应用和储存装置及其使用方法

    公开(公告)号：US20050106753A1

    公开(公告)日：2005-05-19

    申请号：US10890540

    申请日：2004-07-12

    申请人： Yuchang Wu ,  Fei Gao ,  Huiyan Guo

    发明人： Yuchang Wu ,  Fei Gao ,  Huiyan Guo

    IPC分类号： A61B10/00 ,  B01L3/00 ,  B01L3/02 ,  B01L3/14 ,  G01N20060101 ,  G01N1/10 ,  G01N31/00

    CPC分类号： A61B10/0045 ,  A61B10/0051 ,  A61B10/007 ,  A61B10/0096 ,  B01L3/0272 ,  B01L3/5029 ,  B01L3/50825 ,  B01L2300/046 ,  Y10T436/2575

    摘要： The present disclosure includes but is not limited to a device for collecting samples, especially liquid samples to be tested for the presence of an analyte, especially for drugs of abuse, antibodies, antigens and biological moieties such as steroids and glucose. In particular, the disclosure describes improvements in collection device design that provide a simple, non-invasive, non-hazardous method of collecting samples from a subject or patient, especially liquid samples such as saliva, oral fluid and urine. The collected sample can be stored in the disclosed device and the device can be used to apply, in a drop-wise manner, an aliquot of the sample directly to a test device.

    摘要翻译： 本公开包括但不限于用于收集样品的装置，特别是待测试的液体样品，特别是用于滥用药物，抗体，抗原和生物部分（例如类固醇和葡萄糖）的分析物的存在。 特别地，本公开描述了收集装置设计的改进，其提供从受试者或患者特别是液体样品如唾液，口腔液体和尿液采集样品的简单，非侵入性，非危险的方法。 收集的样品可以存储在所公开的装置中，并且该装置可以用于以逐个方式将样品的等分试样直接应用于测试装置。

    Lateral flow assay devices and methods of use
    7.
    发明申请
    Lateral flow assay devices and methods of use 有权
    侧流测定装置和使用方法

    公开(公告)号：US20050079629A1

    公开(公告)日：2005-04-14

    申请号：US10948093

    申请日：2004-09-23

    申请人： Huiyan Guo ,  Simin Zhu ,  Welson Wu ,  Soar Gao ,  Dale Dai

    发明人： Huiyan Guo ,  Simin Zhu ,  Welson Wu ,  Soar Gao ,  Dale Dai

    IPC分类号： G01N31/22 ,  G01N33/52 ,  G01N33/558

    CPC分类号： G01N33/521 ,  G01N33/525 ,  G01N33/558 ,  Y10T436/25

    摘要： The present invention is directed novel lateral flow devices for analyzing liquid samples. The devices contain chemical test strips and are useful for testing liquids for physical properties, such as pH, specific gravity, contamination or adulteration, the presence of proteins or blood, and the like. The test strips contain a bibulous material, a filter element, a reagent pad, and in some embodiments also contain a hydrophobic member and a cover. Any fluid can be tested, for example, urine or other body fluids, environmental samples, biological samples, clinical samples, or food and beverage samples.

    摘要翻译： 本发明涉及用于分析液体样品的新型侧流装置。 这些装置含有化学测试条，并且可用于测试液体的物理性质，如pH，比重，污染或掺假，蛋白质或血液的存在等。 测试条含有吸水材料，过滤元件，试剂垫，并且在一些实施方案中还含有疏水性构件和覆盖物。 可以测试任何流体，例如尿液或其他体液，环境样品，生物样品，临床样品或食品和饮料样品。

    Lateral flow immunoassay controls
    9.
    发明授权
    Lateral flow immunoassay controls 有权
    侧流免疫测定对照

    公开(公告)号：US08193002B2

    公开(公告)日：2012-06-05

    申请号：US12262079

    申请日：2008-10-30

    申请人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

    发明人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

    IPC分类号： G01N33/53

    CPC分类号： G01N33/521 ,  Y10S436/808 ,  Y10S436/81

    摘要： Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read.

    摘要翻译： 快速侧流免疫测定在临床和家庭环境中具有广泛的应用历史。 这些装置用于测试各种分析物，例如滥用药物，激素，蛋白质，尿液或血浆成分等。 本发明提供了一种改进的程序控制，其向测试用户指示所应用样品的至少一部分已经通过测试条的测试结果区域，并且可选地，测试完成并且可以读取测试结果。

    Lateral flow assay devices with inhibiting backflow of the sample and methods of use
    10.
    发明授权
    Lateral flow assay devices with inhibiting backflow of the sample and methods of use 有权
    具有抑制样品回流的侧流测定装置和使用方法

    公开(公告)号：US07595196B2

    公开(公告)日：2009-09-29

    申请号：US10948093

    申请日：2004-09-23

    申请人： Huiyan Guo ,  Simin Zhu ,  Welson Wu ,  Soar Gao ,  Dale Dai

    发明人： Huiyan Guo ,  Simin Zhu ,  Welson Wu ,  Soar Gao ,  Dale Dai

    IPC分类号： G01N31/16 ,  G01N31/22

    CPC分类号： G01N33/521 ,  G01N33/525 ,  G01N33/558 ,  Y10T436/25

    摘要： The present invention is directed novel lateral flow devices for analyzing liquid samples. The devices contain chemical test strips and are useful for testing liquids for physical properties, such as pH, specific gravity, contamination or adulteration, the presence of proteins or blood, and the like. The test strips contain a bibulous material, a filter element, a reagent pad, and in some embodiments also contain a hydrophobic member and a cover. Any fluid can be tested, for example, urine or other body fluids, environmental samples, biological samples, clinical samples, or food and beverage samples.

    摘要翻译： 本发明涉及用于分析液体样品的新型侧流装置。 这些装置含有化学测试条，并且可用于测试液体的物理性质，如pH，比重，污染或掺假，蛋白质或血液的存在等。 测试条含有吸水材料，过滤元件，试剂垫，并且在一些实施方案中还含有疏水性构件和覆盖物。 可以测试任何流体，例如尿液或其他体液，环境样品，生物样品，临床样品或食品和饮料样品。