公开(公告)号：US20060241636A1

公开(公告)日：2006-10-26

申请号：US11350333

申请日：2006-02-08

申请人： Vincent Novak ,  Kelly Ammann ,  Dennis McDevitt

发明人： Vincent Novak ,  Kelly Ammann ,  Dennis McDevitt

IPC分类号： A61F5/00

CPC分类号： A61B17/152 ,  A61B17/15 ,  A61B17/1732 ,  A61B17/1764 ,  A61B17/8095

摘要： In one form of the present invention, there is provided an apparatus for forming a wedge-like opening in a bone for an open wedge osteotomy, the apparatus comprising: targeting apparatus for identifying a cutting plane through the bone and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the bone; and an apex pin for disposition along the boundary line for providing (i) a positive stop at the boundary line for limiting cutting along the cutting plane, and (ii) a cylindrical opening extending along the boundary line so as to minimize the occurrence of stress risers within the bone when the bone on either side of the cut is moved apart so as to form the wedge-like opening in the bone. In another form of the present invention, there is provided a method for forming a wedge-like opening in a bone for an open wedge osteotomy, the method comprising: positioning targeting apparatus relative to the bone, so as to identify a cutting plane through the bone and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the bone; and positioning an apex pin along the boundary line so as to provide (i) a positive stop at the boundary line for limiting cutting along the cutting plane, and (ii) a cylindrical opening extending along the boundary line so as to minimize the occurrence of stress risers within the bone when the bone on either side of the cut is moved apart so as to form the wedge-like opening in the bone; cutting the bone along the cutting plane, with the cut terminating at the boundary line; and moving the bone on either side of the cut apart so as to form the wedge-like opening in the bone.

摘要翻译： 在本发明的一种形式中，提供了一种用于在用于开放式楔形截骨术的骨中形成楔形开口的装置，该装置包括：用于识别通过骨的切割平面的目标装置和用于终止 切割沿切割平面，其中边界线位于骨内; 以及用于沿着边界线设置的顶针，用于提供（i）沿边界线的正止动件，用于限制沿着切割平面的切割，以及（ii）沿着边界线延伸的圆柱形开口，以便最小化应力的发生 当切割物的任一侧上的骨移开时在骨内立起，从而在骨中形成楔形开口。 在本发明的另一形式中，提供了一种用于在用于开放楔形截骨术的骨中形成楔形开口的方法，所述方法包括：相对于骨定位目标装置，以便通过所述骨头识别切割平面 骨和边界线，用于终止沿切割平面制成的切口，其中边界线位于骨内; 并沿着边界线定位一个顶销，以便提供（i）在边界线处的一个止挡，用于限制沿着切割平面的切割，以及（ii）沿边界线延伸的圆柱形开口，以便最小化 当切口的任一侧上的骨移动分开以在骨中形成楔形开口时，骨内的应力提升器; 沿着切割平面切割骨头，切口终止于边界线; 并且在切割的两侧移动骨骼，以便在骨中形成楔形开口。

公开(公告)号：US08496662B2

公开(公告)日：2013-07-30

申请号：US11350333

申请日：2006-02-08

申请人： Vincent P. Novak ,  Kelly Ammann ,  Dennis McDevitt

发明人： Vincent P. Novak ,  Kelly Ammann ,  Dennis McDevitt

IPC分类号： A61B17/56

CPC分类号： A61B17/152 ,  A61B17/15 ,  A61B17/1732 ,  A61B17/1764 ,  A61B17/8095

摘要： The present application provides an apparatus for forming and method of creating a wedge-like opening in a bone for an open wedge osteotomy by identifying a cutting plane through the bone; and inserting an apex pin along the cutting plane to limit cutting and minimize stress risers in the bone.

摘要翻译： 本申请提供了一种用于形成的装置和通过识别穿过骨头的切割平面在开口楔形截骨术中在骨头中形成楔形开口的方法; 并且沿着切割平面插入顶销以限制切割并使骨中的应力提升最小化。

公开(公告)号：US20060217808A1

公开(公告)日：2006-09-28

申请号：US11352103

申请日：2006-02-09

申请人： Vincent Novak ,  Kelly Ammann

发明人： Vincent Novak ,  Kelly Ammann

IPC分类号： A61F2/44

CPC分类号： A61B17/8095 ,  A61F2002/30736

摘要： In one form of the present invention, there is provided an osteotomy implant for supporting an open wedge osteotomy, the osteotomy implant comprising: a first graft containment arm for disposition along one side of the open wedge osteotomy; a second graft containment arm for disposition along a second, opposite side of the open wedge osteotomy; and a base component for disposition along the mouth of the open wedge osteotomy, the base component being configured to selectively connect the first graft containment arm and the second graft containment arm to one another so as to form a generally wedge-shaped structure, wherein the base component constitutes the thicker end of the wedge. In another form of the present invention, there is provided a method for conducting an open wedge osteotomy, comprising: forming a wedge-like opening in the bone; positioning a first graft containment arm along one side of the wedge-like opening, and positioning a second graft containment arm along a second, opposite side of the wedge-like opening; and positioning a base component along the mouth of the wedge-like opening, the base component being selectively connected to the first graft containment arm and the second graft containment arm so as to form a generally wedge-shaped structure, wherein the base component constitutes the thicker end of the wedge.

摘要翻译： 在本发明的一种形式中，提供了一种用于支撑开放式楔形截骨术的截骨植入物，所述截骨植入物包括：用于沿所述开放性楔形截骨术的一侧设置的第一移植物容纳臂; 第二移植物容纳臂，用于沿开放楔形截骨术的第二相对侧设置; 以及用于沿着所述开放式楔形截骨的口部配置的基部部件，所述基部部件构造成将所述第一移植物容纳臂和所述第二移植物容纳臂彼此选择性地连接以形成大致楔形结构，其中， 基部组件构成楔的较厚端。 在本发明的另一形式中，提供了一种用于进行开放楔形截骨术的方法，包括：在所述骨中形成楔形开口; 沿着所述楔形开口的一侧定位第一移植物容纳臂，并且沿所述楔形开口的第二相对侧定位第二移植物容纳臂; 并且沿着所述楔形开口的口部定位基部部件，所述基部部件选择性地连接到所述第一移植物容纳臂和所述第二移植物容纳臂，以形成大致楔形结构，其中所述基部部件构成 较厚的楔形端。

公开(公告)号：US20070244487A1

公开(公告)日：2007-10-18

申请号：US11607321

申请日：2006-12-01

申请人： Kelly Ammann ,  Vincent Novak ,  Robert Schneider ,  Ralph Burns

发明人： Kelly Ammann ,  Vincent Novak ,  Robert Schneider ,  Ralph Burns

IPC分类号： A61B17/58

CPC分类号： A61B17/1675 ,  A61B17/15 ,  A61B17/152 ,  A61B17/1615 ,  A61B17/1732 ,  A61B17/1764 ,  A61B17/68 ,  A61B17/8095 ,  A61B2017/1602 ,  A61B2090/034 ,  A61F2002/30736

摘要： Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising: a wedge-shaped implant for disposition in a wedge-shaped opening created in the tibia, wherein the wedge-shaped implant comprises at least two keys, laterally offset from one another, for disposition in corresponding keyholes formed in the tibia adjacent to the wedge-shaped opening created in the tibia. Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising: a wedge-shaped implant for disposition in a wedge-shaped opening created in the tibia, wherein the wedge-shaped implant comprises at least two keys, vertically offset from one another, for disposition in corresponding keyholes formed in the tibia adjacent to the wedge-shaped opening created in the tibia, and a shear rib, laterally offset from the at least two keys, for disposition in a corresponding shear rib keyhole formed in the tibia adjacent to the wedge-shaped opening created in the tibia.

摘要翻译： 用于执行开放楔形，高胫骨截骨术的装置，所述装置包括：楔形植入物，用于设置在胫骨中形成的楔形开口，其中所述楔形植入物包括至少两个彼此横向偏移的键 ，用于配置在与在胫骨中形成的楔形开口相邻的胫骨中形成的相应的键槽中。 用于执行开放楔形物，高胫骨截骨术的装置，所述装置包括：楔形植入物，用于设置在胫骨中形成的楔形开口，其中所述楔形植入物包括彼此垂直偏移的至少两个键 用于配置在与在胫骨中形成的楔形开口相邻的胫骨中形成的相应的钥匙孔中，以及剪切肋，所述剪切肋从所述至少两个键横向偏移，用于配置在相邻的胫骨中形成的对应的剪切肋锁孔中 在胫骨处形成的楔形开口。

公开(公告)号：US20070213830A1

公开(公告)日：2007-09-13

申请号：US11644218

申请日：2006-12-22

申请人： Kelly Ammann ,  Vincent Novak ,  Robert Schneider ,  Ralph Burns

发明人： Kelly Ammann ,  Vincent Novak ,  Robert Schneider ,  Ralph Burns

IPC分类号： A61F2/38

CPC分类号： A61B17/15 ,  A61B17/02 ,  A61B17/152 ,  A61B17/1615 ,  A61B17/1675 ,  A61B17/1732 ,  A61B17/1764 ,  A61B17/68 ,  A61B17/8095 ,  A61B17/88 ,  A61B2017/1602 ,  A61B2090/034 ,  A61B2090/067 ,  A61F2002/30736

摘要： Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising a wedge-shaped implant for disposition in a wedge-shaped opening created in the tibia, wherein the wedge-shaped implant comprises at least one key for disposition in at least one corresponding keyhole formed in the tibia adjacent to the wedge-shaped opening created in the tibia, wherein each of the at least one keys comprises an interior bore for receiving a fixation screw, at least one fixation screw for disposition in the interior bore of the at least one key, and further wherein the apparatus is configured so that when the at least one fixation screw is received in the interior bore, the at least one fixation screw terminates within the bore.

摘要翻译： 用于执行开放楔形，高胫骨截骨术的装置，所述装置包括楔形植入物，用于设置在胫骨中形成的楔形开口，其中所述楔形植入物包括至少一个键，用于至少一个对应的 形成在与胫骨中形成的楔形开口相邻的胫骨中的锁孔，其中至少一个键中的每一个包括用于接收固定螺钉的内孔，至少一个固定螺钉，用于配置在至少 一个键，并且其中所述装置被配置成使得当所述至少一个固定螺钉被容纳在所述内孔中时，所述至少一个固定螺钉终止于所述孔内。

公开(公告)号：US20070016209A1

公开(公告)日：2007-01-18

申请号：US11396490

申请日：2006-04-03

申请人： Kelly Ammann ,  Vincent Novak ,  Robert Schneider ,  Ralph Burns

发明人： Kelly Ammann ,  Vincent Novak ,  Robert Schneider ,  Ralph Burns

IPC分类号： A61B17/00

CPC分类号： A61B17/1764 ,  A61B17/15 ,  A61B17/152 ,  A61B17/1675 ,  A61B17/1732 ,  A61B17/68 ,  A61B17/8095 ,  A61B90/03 ,  A61B2017/1602

摘要： Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising: cutting apparatus for forming an osteotomy cut in the tibia, the cutting apparatus comprising: targeting apparatus for identifying a cutting plane through the tibia and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the tibia, parallel to the anterior-posterior slope of the tibia and parallel to the sagittal plane of the patient. A method for performing an open wedge, high tibial osteotomy, the method comprising: positioning targeting apparatus for identifying a cutting plane through the tibia and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the tibia, parallel to the anterior-posterior slope of the tibia and parallel to the sagittal plane of the patient; cutting the bone along the cutting plane, with the cut terminating at the boundary line; moving the bone on either side of the cut apart so as to form the wedge-like opening in the bone; and stabilizing the bone.

摘要翻译： 用于执行开放式楔形物，高胫骨截骨术的装置，所述装置包括：用于在胫骨中切割截骨的切割装置，所述切割装置包括：用于识别穿过胫骨的切割平面的靶向装置和用于终止切割的边界线 沿着切割平面，其中边界线位于胫骨内，平行于胫骨的前 - 后斜面并且平行于患者的矢状平面。 一种用于执行开放楔形，高胫骨截骨术的方法，所述方法包括：定位用于通过胫骨识别切割平面的定位装置和用于终止沿切割平面制成的切口的边界线，其中边界线位于胫骨内 平行于胫骨前后斜面并平行于患者的矢状面; 沿着切割平面切割骨头，切口终止于边界线; 在分开的两侧移动骨头，以在骨中形成楔形开口; 并稳定骨骼。

公开(公告)号：US20080208197A1

公开(公告)日：2008-08-28

申请号：US11998473

申请日：2007-11-30

申请人： Kelly Ammann ,  Vincent P. Novak ,  Robert Schneider

发明人： Kelly Ammann ,  Vincent P. Novak ,  Robert Schneider

IPC分类号： A61F5/00

CPC分类号： A61B17/15 ,  A61B17/152 ,  A61B17/1615 ,  A61B17/1675 ,  A61B17/1732 ,  A61B17/1764 ,  A61B2017/00004 ,  A61B2017/1602 ,  A61B2090/034

摘要： A method for performing an open wedge, high tibial osteotomy, the method comprising: identifying a cutting plane through the tibia and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the tibia, parallel to the anterior-posterior slope of the tibia and parallel to the sagittal plane of the patient; positioning a hollow cylinder adjacent to an exterior surface of the tibia and co-axial with the boundary line; positioning a fluoroscope so that its field of view is parallel to the anterior-posterior slope of the tibia, parallel to the sagittal plane of the patient, and co-axial with the hollow cylinder; imaging with the fluoroscope and observing the profile of the hollow cylinder so as to confirm that the hollow cylinder is aligned co-axial with the boundary line; advancing an apex pin through the hollow cylinder and into the tibia along the boundary line so as to provide a positive stop at the boundary line for limiting cutting along the cutting plane; cutting the tibia along the cutting plane, with the cut terminating at the boundary line; moving the tibia on either side of the cut apart so as to form a wedge-like opening in the tibia; and stabilizing the tibia. A method for performing an open wedge, high tibial osteotomy, the method comprising: identifying a cutting plane through the tibia and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the tibia, parallel to the anterior-posterior slope of the tibia and parallel to the sagittal plane of the patient; positioning a hollow apex pin adjacent to an exterior surface of the tibia and co-axial with the boundary line; positioning a fluoroscope so that its field of view is parallel to the anterior-posterior slope of the tibia, parallel to the sagittal plane of the patient, and co-axial with the hollow apex pin; imaging with the fluoroscope and observing the profile of the hollow apex pin so as to confirm that the hollow apex pin is aligned co-axial with the boundary line; advancing the hollow apex pin into the tibia along the boundary line so as to provide a positive stop at the boundary line for limiting cutting along the cutting plane; cutting the tibia along the cutting plane, with the cut terminating at the boundary line; moving the tibia on either side of the cut apart so as to form a wedge-like opening in the tibia; and stabilizing the tibia.

公开(公告)号：US20050239127A1

公开(公告)日：2005-10-27

申请号：US11169112

申请日：2005-06-29

申请人： Kelly Ammann ,  Ralph Burns ,  Ernest Hansberry ,  Glenn Horner ,  Cheryl Jakub ,  John Kling ,  Donald Nieglos ,  Robert Schneider ,  Robert Smith

发明人： Kelly Ammann ,  Ralph Burns ,  Ernest Hansberry ,  Glenn Horner ,  Cheryl Jakub ,  John Kling ,  Donald Nieglos ,  Robert Schneider ,  Robert Smith

IPC分类号： B01L99/00 ,  B01F9/00 ,  B01F15/00 ,  B01L7/00 ,  C12M1/00 ,  C12M1/34 ,  C12M1/36 ,  C12P19/34 ,  C12Q1/68 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10

CPC分类号： C12Q1/6834 ,  B01F9/0001 ,  B01F9/0014 ,  B01F9/0021 ,  B01F2009/0074 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/06 ,  B01L2200/147 ,  B01L2300/1822 ,  B01L2300/1827 ,  B03C1/282 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/26 ,  C12Q1/6813 ,  C12Q1/6832 ,  C12Q2537/10 ,  G01N35/0098 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1065 ,  G01N2035/00356 ,  G01N2035/00524 ,  G01N2035/0437 ,  G01N2035/0455 ,  G01N2035/103 ,  Y10T29/53657 ,  Y10T29/53683 ,  Y10T29/53843 ,  Y10T156/1105 ,  Y10T156/1906 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/113332 ,  Y10T436/114998 ,  Y10T436/119163 ,  Y10T436/2575

摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

摘要翻译： 用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品，在规定温度下规定时间孵育样品，预处理分析物分离程序以及确定目标分析物的存在的站。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及 用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来实现，用于孵化反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。

公开(公告)号：US08888785B2

公开(公告)日：2014-11-18

申请号：US11396490

申请日：2006-04-03

申请人： Kelly Ammann ,  Vincent P. Novak ,  Robert Schneider ,  Ralph E. Burns

发明人： Kelly Ammann ,  Vincent P. Novak ,  Robert Schneider ,  Ralph E. Burns

IPC分类号： A61B17/29 ,  A61B17/17 ,  A61B17/15 ,  A61B17/68 ,  A61B17/16 ,  A61B19/00 ,  A61B17/80

CPC分类号： A61B17/1764 ,  A61B17/15 ,  A61B17/152 ,  A61B17/1675 ,  A61B17/1732 ,  A61B17/68 ,  A61B17/8095 ,  A61B90/03 ,  A61B2017/1602

摘要： An apparatus and method for performing an open wedge osteotomy. The apparatus includes devices for forming an open wedge osteotomy in bone, including a keyed-wedge implant. The method includes the steps of forming a cut in a bone, forming a keyhole in the bone surface at the proximal end of the cut, and positioning a keyed wedge-shaped implant into the cut formed into the bone.

摘要翻译： 用于执行开放性楔形截骨术的装置和方法。 该装置包括用于在骨中形成开放楔形截骨术的装置，包括楔形楔植入物。 该方法包括以下步骤：在骨头中形成切口，在切口的近端处在骨表面中形成锁孔，并将楔形楔形植入物定位到形成骨中的切口中。

公开(公告)号：US20050233370A1

公开(公告)日：2005-10-20

申请号：US11134323

申请日：2005-05-23

申请人： Kelly Ammann ,  Ernest Hansberry

发明人： Kelly Ammann ,  Ernest Hansberry

IPC分类号： B01L99/00 ,  B01F9/00 ,  B01F15/00 ,  B01L7/00 ,  C12M1/00 ,  C12M1/34 ,  C12M1/36 ,  C12P19/34 ,  C12Q1/68 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10

CPC分类号： C12Q1/6834 ,  B01F9/0001 ,  B01F9/0014 ,  B01F9/0021 ,  B01F2009/0074 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/06 ,  B01L2200/147 ,  B01L2300/1822 ,  B01L2300/1827 ,  B03C1/282 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/26 ,  C12Q1/6813 ,  C12Q1/6832 ,  C12Q2537/10 ,  G01N35/0098 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1065 ,  G01N2035/00356 ,  G01N2035/00524 ,  G01N2035/0437 ,  G01N2035/0455 ,  G01N2035/103 ,  Y10T29/53657 ,  Y10T29/53683 ,  Y10T29/53843 ,  Y10T156/1105 ,  Y10T156/1906 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/113332 ,  Y10T436/114998 ,  Y10T436/119163 ,  Y10T436/2575

摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

摘要翻译： 用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品，在规定温度下规定时间孵育样品，预处理分析物分离程序以及确定目标分析物的存在的站。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及 用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行，用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。