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公开(公告)号:US08735054B1
公开(公告)日:2014-05-27
申请号:US12348188
申请日:2009-01-02
申请人: Wendell Sun , Jerome Connor , Qing-Qing Qiu , Rick Owens , Mark Hayzlett
发明人: Wendell Sun , Jerome Connor , Qing-Qing Qiu , Rick Owens , Mark Hayzlett
IPC分类号: A01N1/00
CPC分类号: A01N1/0294 , A01N1/00 , A01N1/0215
摘要: The present disclosure provides a variety of methods and compositions (e.g., solutions) useful for making, sterilizing, and preserving tissues (e.g., acellular tissue matrices). The disclosure also features the acellular tissue matrices made by the methods, which matrices can be used for a variety of applications such as, but not limited to, treating an injury to, or repairing, a large number of tissues and/or organs (e.g., e.g., fascia, bones, and/or cartilage) in a mammal (e.g., a human).
摘要翻译: 本公开提供了可用于制备,消毒和保存组织(例如,无细胞组织基质)的各种方法和组合物(例如,溶液)。 本公开还具有通过该方法制备的无细胞组织基质,该基质可用于多种应用,例如但不限于治疗大量组织和/或器官的损伤或修复(例如, 例如筋膜,骨骼和/或软骨)在哺乳动物(例如人)中。
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公开(公告)号:US09150318B1
公开(公告)日:2015-10-06
申请号:US12650902
申请日:2009-12-31
申请人: Wendell Sun , Jerome Connor , Qing-Qing Qiu , Rick Owens
发明人: Wendell Sun , Jerome Connor , Qing-Qing Qiu , Rick Owens
CPC分类号: B65B55/02 , A61L2/0029 , A61L2/0035 , A61L2/007 , A61L2430/40 , B65B31/02 , B65B55/08 , B65B55/16 , B65B55/22
摘要: The present disclosure provides a variety of methods and compositions useful for making, sterilizing, and preserving tissues. The disclosure also features the acellular tissue matrices made by the methods.
摘要翻译: 本公开提供了用于制备,灭菌和保存组织的各种方法和组合物。 本公开还具有通过该方法制备的无细胞组织基质。
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公开(公告)号:US20110238186A1
公开(公告)日:2011-09-29
申请号:US13070891
申请日:2011-03-24
申请人: Rick Owens , Wendell Sun , Mike Liu , Yong Mao
发明人: Rick Owens , Wendell Sun , Mike Liu , Yong Mao
CPC分类号: A61F2/0063 , A61L27/3633 , A61L27/48
摘要: Devices and methods for treating or repairing a tissue or organ defect or injury are provided. The devices can include tissue scaffolds produced from acellular tissue matrices and polymers, which have a stable three-dimensional shape and elicit a limited immunologic or inflammatory response.
摘要翻译: 提供了用于治疗或修复组织或器官缺损或损伤的装置和方法。 该装置可以包括由无细胞组织基质和聚合物产生的组织支架,其具有稳定的三维形状并且引起有限的免疫学或炎症反应。
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公开(公告)号:US08784499B2
公开(公告)日:2014-07-22
申请号:US13070891
申请日:2011-03-24
申请人: Rick Owens , Wendell Sun , Mike Liu , Yong Mao
发明人: Rick Owens , Wendell Sun , Mike Liu , Yong Mao
IPC分类号: A61F2/28
CPC分类号: A61F2/0063 , A61L27/3633 , A61L27/48
摘要: Devices and methods for treating or repairing a tissue or organ defect or injury are provided. The devices can include tissue scaffolds produced from acellular tissue matrices and polymers, which have a stable three-dimensional shape and elicit a limited immunologic or inflammatory response.
摘要翻译: 提供了用于治疗或修复组织或器官缺损或损伤的装置和方法。 该装置可以包括由无细胞组织基质和聚合物产生的组织支架,其具有稳定的三维形状并且引起有限的免疫学或炎症反应。
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公开(公告)号:US09301020B2
公开(公告)日:2016-03-29
申请号:US12956403
申请日:2010-11-30
申请人: Wendell Sun
发明人: Wendell Sun
IPC分类号: G06F15/16 , H04N21/81 , H04N21/262 , H04N21/44 , H04N21/61 , H04N21/845 , H04L29/06 , H04L29/08
CPC分类号: H04N21/812 , G11B27/10 , H04L29/06 , H04L29/06027 , H04L29/06462 , H04L29/08576 , H04N21/23109 , H04N21/23424 , H04N21/25891 , H04N21/26258 , H04N21/44016 , H04N21/4532 , H04N21/4825 , H04N21/6125 , H04N21/8456
摘要: A content delivery system and method that receives a request for a content stream that includes splice points. The method receives a playlist that includes an ordered list of media segment files that represent the content stream, and splice point tags, where generation of the media segment files aligns segment boundaries with the splice points in the content stream, and where each splice point tag is in a location in the playlist that corresponds to the position of one of the splice points in the content stream. The method identifies an insertion position in the playlist based on the location of the splice point tags, selects an advertisement segment, inserts the advertisement segment at the insertion position to create a modified playlist, removes the splice point tags from the modified playlist, and sends the modified playlist to the video display device.
摘要翻译: 一种内容传送系统和方法,其接收对包含拼接点的内容流的请求。 该方法接收包括表示内容流的媒体段文件的有序列表的播放列表,以及拼接点标签,其中媒体段文件的生成将段边界与内容流中的拼接点对齐,并且其中每个拼接点标签 位于播放列表中与内容流中的一个拼接点的位置相对应的位置。 该方法基于拼接点标签的位置识别播放列表中的插入位置,选择广告段,在插入位置插入广告段以创建修改的播放列表,从修改的播放列表中删除拼接点标签,并发送 修改的播放列表到视频显示设备。
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公开(公告)号:US09259511B2
公开(公告)日:2016-02-16
申请号:US12478435
申请日:2009-06-04
申请人: Wendell Sun
发明人: Wendell Sun
IPC分类号: A61L27/36
CPC分类号: A61L27/3687 , A61L27/3604 , A61L27/362 , F01C21/06 , F03C2/08
摘要: A method of producing a modified acellular tissue matrix (mATM) from an acellular tissue matrix (ATM), where the mATM has a reduced stretchiness relative to the ATM, without substantially compromising its associated structural or functional integrity. The method includes providing an acellular tissue matrix (ATM) and exposing the ATM to elastase for a period of time.
摘要翻译: 从无细胞组织基质(ATM)产生修饰的无细胞组织基质(mATM)的方法,其中mATM相对于ATM具有降低的拉伸性,而基本上不损害其相关的结构或功能完整性。 该方法包括提供无细胞组织基质(ATM)并将ATM暴露于弹性蛋白酶一段时间。
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公开(公告)号:US08451833B2
公开(公告)日:2013-05-28
申请号:US11956652
申请日:2007-12-14
申请人: Raja Kolli , Garrett Mead , John Reister , Christopher J. Shaver , Wendell Sun , Mark Tiedeman
发明人: Raja Kolli , Garrett Mead , John Reister , Christopher J. Shaver , Wendell Sun , Mark Tiedeman
IPC分类号: H04L12/28
CPC分类号: H04L12/2856 , H04L12/289 , H04L29/12207 , H04L29/12933 , H04L61/20 , H04L61/6068
摘要: A transparent routing device disposed within an access network configured in accordance with one or more lower-layer protocols is disclosed herein. The device includes a set of subscriber-side ports. Each of the subscriber-side ports is associated with a plurality of virtual subscriber-side interfaces disposed to effectively terminate a corresponding plurality of subscriber-side connections with subscriber host devices served by the access network. The device further includes at least one network-side port through which communication occurs with an external network in accordance with a higher-layer protocol. A routing table is configured to establish a correspondence between network addresses of the subscriber host devices and the plurality of virtual subscriber-side interfaces. During operation of the device, packets received through the at least one network-side port are forwarded to corresponding ones of the virtual subscriber-side interfaces based upon network addresses of the packets.
摘要翻译: 本文公开了布置在根据一个或多个下层协议配置的接入网络内的透明路由设备。 该设备包括一组用户端口。 每个用户侧端口与多个虚拟用户侧接口相关联,多个虚拟用户侧接口被设置为有效地终止与由接入网络服务的用户主机设备相对应的多个用户侧连接。 该设备还包括至少一个网络侧端口,根据较高层协议,与外部网络进行通信的至少一个网络侧端口。 路由表被配置为建立用户主机设备的网络地址与多个虚拟用户侧接口之间的对应关系。 在设备运行期间,基于分组的网络地址,通过至少一个网络侧端口接收到的分组被转发到虚拟用户侧接口中的相应虚拟用户侧接口。
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公开(公告)号:US08036237B2
公开(公告)日:2011-10-11
申请号:US11956640
申请日:2007-12-14
申请人: Raja Kolli , Garrett Mead , John Reister , Christopher J. Shaver , Wendell Sun , Mark Tiedeman
发明人: Raja Kolli , Garrett Mead , John Reister , Christopher J. Shaver , Wendell Sun , Mark Tiedeman
IPC分类号: H04L12/28
CPC分类号: H04L12/2856 , H04L12/2865 , H04L12/2887 , H04L12/289 , H04L29/12207 , H04L29/12933 , H04L61/20 , H04L61/6068
摘要: A transparent routing device disposed within an access network configured in accordance with one or more lower-layer protocols is disclosed herein. The device includes a set of subscriber-side ports. Each of the subscriber-side ports is associated with a plurality of virtual subscriber-side interfaces disposed to effectively terminate a corresponding plurality of subscriber-side connections with subscriber host devices served by the access network. The device further includes at least one network-side port through which communication occurs with an external network in accordance with a higher-layer protocol. A routing table is configured to establish a correspondence between network addresses of the subscriber host devices and the plurality of virtual subscriber-side interfaces. During operation of the device, packets received through the at least one network-side port are forwarded to corresponding ones of the virtual subscriber-side interfaces based upon network addresses of the packets.
摘要翻译: 本文公开了布置在根据一个或多个下层协议配置的接入网络内的透明路由设备。 该设备包括一组用户端口。 每个用户侧端口与多个虚拟用户侧接口相关联,多个虚拟用户侧接口被设置为有效地终止与由接入网络服务的用户主机设备相对应的多个用户侧连接。 该设备还包括至少一个网络侧端口,根据较高层协议,与外部网络进行通信的至少一个网络侧端口。 路由表被配置为建立用户主机设备的网络地址与多个虚拟用户侧接口之间的对应关系。 在设备运行期间,基于分组的网络地址,通过至少一个网络侧端口接收到的分组被转发到虚拟用户侧接口中的相应虚拟用户侧接口。
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公开(公告)号:US10448951B2
公开(公告)日:2019-10-22
申请号:US13029487
申请日:2011-02-17
申请人: Eric Stevenson , Wendell Sun , Aaron Barere
发明人: Eric Stevenson , Wendell Sun , Aaron Barere
摘要: Devices and methods for treating or repairing openings in an body wall are provided. The devices and methods can include acellular tissue matrices. The tissue matrices can be positioned within the abdominal opening and can be used to close the opening.
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公开(公告)号:US09636435B2
公开(公告)日:2017-05-02
申请号:US13177720
申请日:2011-07-07
申请人: Wendell Sun , Gary Monteiro
发明人: Wendell Sun , Gary Monteiro
CPC分类号: A61L27/24 , A61F2/12 , A61F2/186 , A61L27/3604 , A61L27/362 , A61L27/3641 , A61L27/3691 , A61L27/50 , A61L2430/04 , A61L2430/40 , C12N5/0081
摘要: Methods for shaping tissue matrices are provided. The methods can be used to produce shaped tissue products that retain desired biologic properties without using chemical crosslinking agents.
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