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公开(公告)号：US20080239306A1
公开(公告)日：2008-10-02
申请号：US11693277
申请日：2007-03-29
申请人： William Scott Sutherland , Anis Zribi , Long Que , Glenn Scott Claydon , Stacey Joy Kennerly , Ayan Banerjee , Shivappa Ningappa Goravar , Shankar Chandrasekaran , David Cecil Hays , Victor Samper , Dirk Lange , Marko Baller , Min-Yi Shih , Sandip Maity
发明人： William Scott Sutherland , Anis Zribi , Long Que , Glenn Scott Claydon , Stacey Joy Kennerly , Ayan Banerjee , Shivappa Ningappa Goravar , Shankar Chandrasekaran , David Cecil Hays , Victor Samper , Dirk Lange , Marko Baller , Min-Yi Shih , Sandip Maity
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01J3/0232 , G01J3/0237 , G01J3/027 , G01J3/0289 , G01J3/10 , G01J3/1895 , G01J3/44 , G02B26/02 , G02B26/0808 , G02B26/0816
摘要： A system and method for managing optical power for controlling thermal alteration of a sample undergoing spectroscopic analysis is provided. The system includes a moveable laser beam generator for irradiating the sample and a beam shaping device for moving and shaping the laser beam to prevent thermal overload or build up in the sample. The moveable laser beam generator includes at least one beam shaping device selected from the group consisting of at least one optical lens, at least one optical diffractor, at least one optical path difference modulator, at least one moveable mirror, at least one Micro-Electro-Mechanical Systems (MEMS) integrated circuit (IC), and/or a liquid droplet. The system also includes an at least two degree of freedom (2 DOF) moveable substrate platform and a controller for controlling the laser beam generator and the substrate platform, and for analyzing light reflected from the sample.
摘要翻译： 提供了一种用于管理用于控制进行光谱分析的样品的热变化的光功率的系统和方法。 该系统包括用于照射样品的可移动激光束发生器和用于移动和成形激光束的光束整形装置，以防止样品中的热过载或积聚。 可移动激光束发生器包括至少一个光束成形装置，其选自由至少一个光学透镜，至少一个光学衍射器，至少一个光程差调制器，至少一个可动反射镜，至少一个微电极 机电系统（MEMS）集成电路（IC）和/或液滴。 该系统还包括至少两个自由度（2自由度）可移动基板平台和用于控制激光束发生器和基板平台的控制器，并用于分析从样品反射的光。
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公开(公告)号：US07692785B2
公开(公告)日：2010-04-06
申请号：US11693277
申请日：2007-03-29
申请人： Willam Scott Sutherland , Anis Zribi , Long Que , Glenn Scott Claydon , Stacey Joy Kennerly , Ayan Banerjee , Shivappa Ningappa Goravar , Shankar Chandrasekaran , David Cecil Hays , Victor Samper , Dirk Lange , Marko Baller , Min-Yi Shih , Sandip Maity
发明人： Willam Scott Sutherland , Anis Zribi , Long Que , Glenn Scott Claydon , Stacey Joy Kennerly , Ayan Banerjee , Shivappa Ningappa Goravar , Shankar Chandrasekaran , David Cecil Hays , Victor Samper , Dirk Lange , Marko Baller , Min-Yi Shih , Sandip Maity
IPC分类号： G01J3/44
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01J3/0232 , G01J3/0237 , G01J3/027 , G01J3/0289 , G01J3/10 , G01J3/1895 , G01J3/44 , G02B26/02 , G02B26/0808 , G02B26/0816
摘要： A system and method for managing optical power for controlling thermal alteration of a sample undergoing spectroscopic analysis is provided. The system includes a moveable laser beam generator for irradiating the sample and a beam shaping device for moving and shaping the laser beam to prevent thermal overload or build up in the sample. The moveable laser beam generator includes at least one beam shaping device selected from the group consisting of at least one optical lens, at least one optical diffractor, at least one optical path difference modulator, at least one moveable mirror, at least one Micro-Electro-Mechanical Systems (MEMS) integrated circuit (IC), and/or a liquid droplet. The system also includes an at least two degree of freedom (2 DOF) moveable substrate platform and a controller for controlling the laser beam generator and the substrate platform, and for analyzing light reflected from the sample.
摘要翻译： 提供了一种用于管理用于控制进行光谱分析的样品的热变化的光功率的系统和方法。 该系统包括用于照射样品的可移动激光束发生器和用于移动和成形激光束的光束整形装置，以防止样品中的热过载或积聚。 可移动激光束发生器包括至少一个光束成形装置，其选自由至少一个光学透镜，至少一个光学衍射器，至少一个光程差调制器，至少一个可动反射镜，至少一个微电极 机电系统（MEMS）集成电路（IC）和/或液滴。 该系统还包括至少两个自由度（2自由度）可移动基板平台和用于控制激光束发生器和基板平台的控制器，并用于分析从样品反射的光。
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3.发明申请公开(公告)号：US20080084565A1
公开(公告)日：2008-04-10
申请号：US11538885
申请日：2006-10-05
申请人： Anis Zribi , Min-Yi Shih , Guiju Song , Ajit Achuthan , Glenn Scott Claydon , Stacey Joy Kennerly , Kuna Venkat Satya Rama Kishore , Jianming Zheng , Kevin George Harding , Hua Xia
发明人： Anis Zribi , Min-Yi Shih , Guiju Song , Ajit Achuthan , Glenn Scott Claydon , Stacey Joy Kennerly , Kuna Venkat Satya Rama Kishore , Jianming Zheng , Kevin George Harding , Hua Xia
IPC分类号： G01B9/02
CPC分类号： G01D5/35303 , G01D5/268 , G01N17/008 , G01N21/45 , G01N21/8422 , G01N2021/458 , G01N2021/9546
摘要： A interferometer-based fouling detection system and method are described. The system may include a fiber optic cable, a light source in communication with the fiber optic cable, at least one photo detector in communication with the fiber optic cable, and at least one interferometric spectrometer. The fiber optic cable may include a long period grating and a fiber Bragg grating or it may include a facet edge. The system may instead include a fiber optic cable, a light source in communication with the fiber optic cable, at least one photo detector in communication with the fiber optic cable, a fiber coupler, a reference probe including a mirror, a sample probe, and an interferometer.
摘要翻译： 描述了基于干涉仪的结垢检测系统和方法。 该系统可以包括光纤电缆，与光纤电缆通信的光源，与光纤电缆通信的至少一个光电检测器，以及至少一个干涉光谱仪。 光纤电缆可以包括长周期光栅和光纤布拉格光栅，或者它可以包括小面边缘。 该系统可以替代地包括光纤电缆，与光纤电缆通信的光源，与光纤电缆通信的至少一个光电检测器，光纤耦合器，包括反射镜的参考探针，样本探针和 干涉仪。
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4.发明授权公开(公告)号：US07428055B2
公开(公告)日：2008-09-23
申请号：US11538885
申请日：2006-10-05
申请人： Anis Zribi , Min-Yi Shih , Guiju Song , Ajit Achuthan , Glenn Scott Claydon , Stacey Joy Kennerly , Kuna Venkat Satya Rama Kishore , Jianming Zheng , Kevin George Harding , Hua Xia
发明人： Anis Zribi , Min-Yi Shih , Guiju Song , Ajit Achuthan , Glenn Scott Claydon , Stacey Joy Kennerly , Kuna Venkat Satya Rama Kishore , Jianming Zheng , Kevin George Harding , Hua Xia
CPC分类号： G01D5/35303 , G01D5/268 , G01N17/008 , G01N21/45 , G01N21/8422 , G01N2021/458 , G01N2021/9546
摘要： A interferometer-based fouling detection system and method are described. The system may include a fiber optic cable, a light source in communication with the fiber optic cable, at least one photo detector in communication with the fiber optic cable, and at least one interferometric spectrometer. The fiber optic cable may include a long period grating and a fiber Bragg grating or it may include a facet edge. The system may instead include a fiber optic cable, a light source in communication with the fiber optic cable, at least one photo detector in communication with the fiber optic cable, a fiber coupler, a reference probe including a mirror, a sample probe, and an interferometer.
摘要翻译： 描述了基于干涉仪的结垢检测系统和方法。 该系统可以包括光纤电缆，与光纤电缆通信的光源，与光纤电缆通信的至少一个光电检测器，以及至少一个干涉光谱仪。 光纤电缆可以包括长周期光栅和光纤布拉格光栅，或者它可以包括小面边缘。 该系统可以替代地包括光纤电缆，与光纤电缆通信的光源，与光纤电缆通信的至少一个光电检测器，光纤耦合器，包括反射镜的参考探针，样本探针和 干涉仪。
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公开(公告)号：US20090201497A1
公开(公告)日：2009-08-13
申请号：US11400947
申请日：2006-04-10
申请人： Anis Zribi , Wei-Cheng Tian , Yuan-Hsiang Lee , Min-Yi Shih
发明人： Anis Zribi , Wei-Cheng Tian , Yuan-Hsiang Lee , Min-Yi Shih
CPC分类号： G01N21/0303 , G01N21/658 , G01N30/74 , G01N2021/651 , G02B6/10 , G02B2006/1213
摘要： An optofluidic device is provided. The device includes a cladding region having a first refractive index, and a channel defined by the cladding region such that the cladding region forms an inner surface or an interface of the channel. The channel is configured to house one or more of a liquid, a solid, a gas, a colloidal, or a suspension sample, wherein the sample has a second refractive index, where the channel is configured to guide radiation, and where the first refractive index is lower than the second refractive index.
摘要翻译： 提供了一种光流体装置。 该器件包括具有第一折射率的包层区域和由包层区域限定的沟道，使得包层区域形成沟道的内表面或界面。 通道被配置成容纳液体，固体，气体，胶体或悬浮样品中的一种或多种，其中样品具有第二折射率，其中通道被构造成引导辐射，并且其中第一折射 指数低于第二折射率。
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公开(公告)号：US20070004975A1
公开(公告)日：2007-01-04
申请号：US11172648
申请日：2005-06-30
申请人： Anis Zribi , Peter Codella , Min-Yi Shih , Ganesh Gangadharan , Rui Chen
发明人： Anis Zribi , Peter Codella , Min-Yi Shih , Ganesh Gangadharan , Rui Chen
IPC分类号： A61B5/00
CPC分类号： A61B5/14546 , A61B5/14532 , A61B5/14558 , G01J3/44 , G01J3/447 , G01N21/21 , G01N21/65
摘要： A method for determining analyte concentration levels is provided. The method includes acquiring radiation scattered off or transmitted by a target, analyzing at least a first portion of the radiation via a first technique to generate a first measurement of analyte concentration levels, and analyzing at least a second portion of the radiation via a second technique to generate a second measurement of analyte concentration levels. The method further determines analyte concentration levels based on at least one of the first measurement or the second measurement. In addition, a system for implementing the method and a probe for measuring and monitoring the analyte concentration levels is provided.
摘要翻译： 提供了一种用于确定分析物浓度水平的方法。 该方法包括获取由目标散射或透射的辐射，经由第一技术分析辐射的至少第一部分以产生分析物浓度水平的第一测量，以及通过第二技术分析辐射的至少第二部分 以产生分析物浓度水平的第二次测量。 该方法还基于第一测量或第二测量中的至少一个来确定分析物浓度水平。 另外，提供了用于实现该方法的系统和用于测量和监测分析物浓度水平的探针。
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公开(公告)号：US07627357B2
公开(公告)日：2009-12-01
申请号：US11172648
申请日：2005-06-30
IPC分类号： A61B5/1455
CPC分类号： A61B5/14546 , A61B5/14532 , A61B5/14558 , G01J3/44 , G01J3/447 , G01N21/21 , G01N21/65
摘要： A method for determining analyte concentration levels is provided. The method includes acquiring radiation scattered off or transmitted by a target, analyzing at least a first portion of the radiation via a first technique to generate a first measurement of analyte concentration levels, and analyzing at least a second portion of the radiation via a second technique to generate a second measurement of analyte concentration levels. The method further determines analyte concentration levels based on at least one of the first measurement or the second measurement. In addition, a system for implementing the method and a probe for measuring and monitoring the analyte concentration levels is provided.
摘要翻译： 提供了一种用于确定分析物浓度水平的方法。 该方法包括获取由目标散射或透射的辐射，经由第一技术分析辐射的至少第一部分以产生分析物浓度水平的第一测量，以及通过第二技术分析辐射的至少第二部分 以产生分析物浓度水平的第二次测量。 该方法还基于第一测量或第二测量中的至少一个来确定分析物浓度水平。 另外，提供了用于实现该方法的系统和用于测量和监测分析物浓度水平的探针。
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公开(公告)号：US07574089B1
公开(公告)日：2009-08-11
申请号：US11400947
申请日：2006-04-10
申请人： Anis Zribi , Wei-Cheng Tian , Yuan-Hsiang Lee , Min-Yi Shih
发明人： Anis Zribi , Wei-Cheng Tian , Yuan-Hsiang Lee , Min-Yi Shih
CPC分类号： G01N21/0303 , G01N21/658 , G01N30/74 , G01N2021/651 , G02B6/10 , G02B2006/1213
摘要： An optofluidic device is provided. The device includes a cladding region having a first refractive index, and a channel defined by the cladding region such that the cladding region forms an inner surface or an interface of the channel. The channel is configured to house one or more of a liquid, a solid, a gas, a colloidal, or a suspension sample, wherein the sample has a second refractive index, where the channel is configured to guide radiation, and where the first refractive index is lower than the second refractive index.
摘要翻译： 提供了一种光流体装置。 该器件包括具有第一折射率的包层区域和由包层区域限定的沟道，使得包层区域形成沟道的内表面或界面。 通道被配置成容纳液体，固体，气体，胶体或悬浮样品中的一种或多种，其中样品具有第二折射率，其中通道被构造成引导辐射，并且其中第一折射 指数低于第二折射率。
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公开(公告)号：US07776236B2
公开(公告)日：2010-08-17
申请号：US10628181
申请日：2003-07-25
申请人： Min-Yi Shih , Thomas Bert Gorczyca
发明人： Min-Yi Shih , Thomas Bert Gorczyca
IPC分类号： B29D11/00
CPC分类号： G02B6/138 , G02B6/1221 , G02B6/125
摘要： A method of forming a waveguide including a core region, a cladding region, and an index contrast region situated therebetween includes depositing a polymerizable composite on a substrate to form a layer, patterning the layer to define an exposed area and an unexposed area of the layer, irradiating the exposed area of the layer, and volatilizing the uncured monomer to form the waveguide, wherein the polymerizable composite includes a polymer binder and sufficient quantities of an uncured monomer to diffuse into the exposed area of the layer and form the index contrast region. The resulting waveguide includes an index contrast region which has a lower index of refraction than that of the core and cladding regions.
摘要翻译： 形成包括芯区域，包层区域和位于其间的折射率对比区域的波导的方法包括在基板上沉积可聚合复合物以形成层，图案化该层以限定该层的曝光区域和未曝光区域 照射所述层的暴露区域，并使未固化的单体挥发以形成波导，其中所述可聚合复合材料包括聚合物粘合剂和足够量的未固化的单体以扩散到所述层的暴露区域中并形成所述折射率对比区域。 所得到的波导包括折射率对比度区域，该折射率对比度区域具有比芯部和包层区域更低的折射率。
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公开(公告)号：US20050053346A1
公开(公告)日：2005-03-10
申请号：US10659464
申请日：2003-09-09
申请人： Kung-Li Deng , Thomas Gorczyca , Renato Guida , Matthew Nielsen , Min-Yi Shih , Todd Tolliver
发明人： Kung-Li Deng , Thomas Gorczyca , Renato Guida , Matthew Nielsen , Min-Yi Shih , Todd Tolliver
IPC分类号： G02B6/12 , G02B6/125 , G02B6/138 , G02B6/26 , G02B6/30 , G02B6/32 , G02B6/42 , G02F1/35 , G02B6/10
CPC分类号： G02B6/138 , G02B6/12 , G02B6/125 , G02B6/26 , G02B6/305 , G02B6/32 , G02B6/4212 , G02B6/4214 , G02B6/423 , G02B2006/12173
摘要： A method of forming a waveguide including a core region, a cladding region, and an index contrast region situated therebetween includes depositing a polymerizable composite on a substrate to form a layer, patterning the layer to define an exposed area and an unexposed area of the layer, irradiating the exposed area of the layer, and volatilizing the uncured monomer to form the waveguide, wherein the polymerizable composite includes a polymer binder and sufficient quantities of an uncured monomer to diffuse into the exposed area of the layer and form the index contrast region. The resulting waveguide includes an index contrast region which has a lower index of refraction than that of the core and cladding regions.
摘要翻译： 形成包括芯区域，包层区域和位于其间的折射率对比区域的波导的方法包括在基板上沉积可聚合复合物以形成层，图案化该层以限定该层的曝光区域和未曝光区域 照射所述层的暴露区域，并使未固化的单体挥发以形成波导，其中所述可聚合复合材料包括聚合物粘合剂和足够量的未固化的单体以扩散到所述层的暴露区域中并形成所述折射率对比区域。 所得到的波导包括折射率对比度区域，该折射率对比度区域具有比芯部和包层区域更低的折射率。
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